JP2004533415A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004533415A5 JP2004533415A5 JP2002567288A JP2002567288A JP2004533415A5 JP 2004533415 A5 JP2004533415 A5 JP 2004533415A5 JP 2002567288 A JP2002567288 A JP 2002567288A JP 2002567288 A JP2002567288 A JP 2002567288A JP 2004533415 A5 JP2004533415 A5 JP 2004533415A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- formula
- enantiomer
- phenyl
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 25
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 12
- 208000020925 Bipolar disease Diseases 0.000 claims 6
- 229910052801 chlorine Inorganic materials 0.000 claims 6
- 239000000460 chlorine Substances 0.000 claims 6
- 125000004093 cyano group Chemical group *C#N 0.000 claims 6
- 239000001257 hydrogen Substances 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 206010026749 Mania Diseases 0.000 claims 4
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 3
- 229910052794 bromium Inorganic materials 0.000 claims 3
- 125000001309 chloro group Chemical group Cl* 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 229910052731 fluorine Inorganic materials 0.000 claims 3
- 239000011737 fluorine Substances 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 125000005843 halogen group Chemical group 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 229910052740 iodine Inorganic materials 0.000 claims 3
- 239000011630 iodine Substances 0.000 claims 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 3
- 125000001424 substituent group Chemical group 0.000 claims 3
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 206010021030 Hypomania Diseases 0.000 claims 1
- 208000028683 bipolar I disease Diseases 0.000 claims 1
- 208000025307 bipolar depression Diseases 0.000 claims 1
- 230000002060 circadian Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27168101P | 2001-02-27 | 2001-02-27 | |
| US10/081,766 US6562867B2 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating bipolar disorder |
| PCT/US2002/005297 WO2002067921A1 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating bipolar disorder |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004533415A JP2004533415A (ja) | 2004-11-04 |
| JP2004533415A5 true JP2004533415A5 (enExample) | 2005-12-22 |
| JP4276837B2 JP4276837B2 (ja) | 2009-06-10 |
Family
ID=26765948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567288A Expired - Lifetime JP4276837B2 (ja) | 2001-02-27 | 2002-02-21 | 双極性障害の予防もしくは治療における使用のためのカルバメート化合物 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6562867B2 (enExample) |
| EP (1) | EP1408953B1 (enExample) |
| JP (1) | JP4276837B2 (enExample) |
| KR (1) | KR100946944B1 (enExample) |
| CN (1) | CN1250215C (enExample) |
| AT (1) | ATE324108T1 (enExample) |
| BR (1) | BR0207644A (enExample) |
| CA (1) | CA2439475C (enExample) |
| CY (1) | CY1105330T1 (enExample) |
| CZ (1) | CZ20032300A3 (enExample) |
| DE (1) | DE60210976T2 (enExample) |
| DK (1) | DK1408953T3 (enExample) |
| ES (1) | ES2262801T3 (enExample) |
| HU (1) | HUP0303243A3 (enExample) |
| IL (1) | IL157590A0 (enExample) |
| MX (1) | MXPA03007717A (enExample) |
| MY (1) | MY129304A (enExample) |
| NO (1) | NO20033802L (enExample) |
| NZ (1) | NZ527988A (enExample) |
| PL (1) | PL364638A1 (enExample) |
| PT (1) | PT1408953E (enExample) |
| RS (1) | RS50677B (enExample) |
| RU (1) | RU2300372C2 (enExample) |
| TW (1) | TWI250872B (enExample) |
| WO (1) | WO2002067921A1 (enExample) |
| ZA (1) | ZA200307465B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL365701A1 (en) * | 2000-07-21 | 2005-01-10 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain |
| MXPA03007720A (es) | 2001-02-27 | 2004-11-12 | Johnson & Johnson | Compuestos de carbamato para su uso en la prevencion o el tratamiento de transtornos de ansiedad. |
| DE60220043T2 (de) * | 2001-02-27 | 2008-01-10 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen |
| WO2003007934A1 (en) | 2001-07-16 | 2003-01-30 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain |
| PT1809273E (pt) * | 2004-09-16 | 2010-05-10 | Janssen Pharmaceutica Nv | Utililização de 2-fenil-1,2-etanodiol-(di)carbamatos para tratamento de epileptogénese |
| PL1890684T3 (pl) | 2005-06-08 | 2014-05-30 | Sk Biopharmaceuticals Co Ltd | Leczenie zaburzeń snu i czuwania |
| US20070021501A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods of treating epileptogenesis |
| CN101568362A (zh) * | 2006-10-30 | 2009-10-28 | 詹森药业有限公司 | 治疗抑郁症的方法 |
| JP2010508354A (ja) * | 2006-10-31 | 2010-03-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 広汎性発達障害の処置 |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| WO2014142547A1 (en) * | 2013-03-12 | 2014-09-18 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compound and a composition for neuroprotection comprising the same |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| CN110290788A (zh) * | 2016-12-14 | 2019-09-27 | 爱思开生物制药株式会社 | 氨基甲酸酯化合物用于预防、缓解或治疗双相障碍的用途 |
| KR20200016889A (ko) | 2017-06-02 | 2020-02-17 | 재즈 파마슈티칼즈 아일랜드 리미티드 | 과다 졸림증을 치료하기 위한 방법 및 조성물 |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3278380A (en) * | 1962-02-06 | 1966-10-11 | Armour Pharma | Methods of calming employing diphenyl hydroxy carbamate compounds |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| ES2135062T3 (es) * | 1994-06-16 | 1999-10-16 | Pfizer | Pirazolo y pirrolopiridinas. |
| US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
-
2002
- 2002-02-21 HU HU0303243A patent/HUP0303243A3/hu unknown
- 2002-02-21 RS YUP-678/03A patent/RS50677B/sr unknown
- 2002-02-21 JP JP2002567288A patent/JP4276837B2/ja not_active Expired - Lifetime
- 2002-02-21 WO PCT/US2002/005297 patent/WO2002067921A1/en not_active Ceased
- 2002-02-21 MX MXPA03007717A patent/MXPA03007717A/es active IP Right Grant
- 2002-02-21 PT PT02724984T patent/PT1408953E/pt unknown
- 2002-02-21 CZ CZ20032300A patent/CZ20032300A3/cs unknown
- 2002-02-21 EP EP02724984A patent/EP1408953B1/en not_active Expired - Lifetime
- 2002-02-21 CA CA2439475A patent/CA2439475C/en not_active Expired - Fee Related
- 2002-02-21 IL IL15759002A patent/IL157590A0/xx not_active IP Right Cessation
- 2002-02-21 BR BR0207644-6A patent/BR0207644A/pt not_active Application Discontinuation
- 2002-02-21 KR KR1020037011296A patent/KR100946944B1/ko not_active Expired - Lifetime
- 2002-02-21 US US10/081,766 patent/US6562867B2/en not_active Expired - Lifetime
- 2002-02-21 AT AT02724984T patent/ATE324108T1/de active
- 2002-02-21 NZ NZ527988A patent/NZ527988A/en unknown
- 2002-02-21 CN CNB028089170A patent/CN1250215C/zh not_active Expired - Fee Related
- 2002-02-21 RU RU2003128997/14A patent/RU2300372C2/ru active
- 2002-02-21 DK DK02724984T patent/DK1408953T3/da active
- 2002-02-21 DE DE60210976T patent/DE60210976T2/de not_active Expired - Lifetime
- 2002-02-21 PL PL02364638A patent/PL364638A1/xx not_active Application Discontinuation
- 2002-02-21 ES ES02724984T patent/ES2262801T3/es not_active Expired - Lifetime
- 2002-02-27 MY MYPI20020691A patent/MY129304A/en unknown
- 2002-02-27 TW TW091103500A patent/TWI250872B/zh active
-
2003
- 2003-08-26 NO NO20033802A patent/NO20033802L/no not_active Application Discontinuation
- 2003-09-25 ZA ZA200307465A patent/ZA200307465B/en unknown
-
2006
- 2006-06-21 CY CY20061100844T patent/CY1105330T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004525905A5 (enExample) | ||
| JP2004527492A5 (enExample) | ||
| JP2006526590A5 (enExample) | ||
| JP2009531376A5 (enExample) | ||
| JP2007511504A5 (enExample) | ||
| JP2010502730A5 (enExample) | ||
| JP2004500426A5 (enExample) | ||
| JP2005511547A5 (enExample) | ||
| RU2003128984A (ru) | Производные карбаматов для использования для лечения боли | |
| JP2006504738A5 (enExample) | ||
| JPWO2023195529A5 (enExample) | ||
| JP2004529114A5 (enExample) | ||
| JP2002527414A5 (enExample) | ||
| RU2003128996A (ru) | Карбаматы для применения для предотвращения или лечения биполярного расстройства | |
| CA2439475A1 (en) | Carbamate compounds for use in preventing or treating bipolar disorder | |
| BR0207831A (pt) | Compostos carbamato para uso na prevenção ou tratamento de distúrbios do movimento | |
| JP2004523556A5 (enExample) | ||
| BR0112713A (pt) | "compostos de carbamato para uso na prevenção ou tratamento de dor neuropática e dor associada a cefaléia em cacho e hemicrânia | |
| BR0207830A (pt) | Compostos de carbamato para uso em prevenir ou tratar distúrbios de ansiedade | |
| RU2003128983A (ru) | Производные карбаматов для предотвращения или лечения психотических нарушений | |
| CA2523253A1 (en) | Methyl indoles and methyl pyrrolopyridines as alpha-1 adrenergic agonists | |
| JP2013507438A5 (enExample) | ||
| JP2005516952A5 (enExample) | ||
| JP2006520807A5 (enExample) | ||
| JP2005529110A5 (enExample) |