CN1250215C - 用于预防或治疗双相性精神障碍的氨基甲酸酯化合物 - Google Patents

用于预防或治疗双相性精神障碍的氨基甲酸酯化合物 Download PDF

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Publication number
CN1250215C
CN1250215C CNB028089170A CN02808917A CN1250215C CN 1250215 C CN1250215 C CN 1250215C CN B028089170 A CNB028089170 A CN B028089170A CN 02808917 A CN02808917 A CN 02808917A CN 1250215 C CN1250215 C CN 1250215C
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CN
China
Prior art keywords
formula
enantiomer
bipolar disorder
use according
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB028089170A
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English (en)
Chinese (zh)
Other versions
CN1505506A (zh
Inventor
C·R·普拉塔-萨拉曼
赵柏羽
R·E·特伊曼
崔溶文
R·戈顿
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
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Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of CN1505506A publication Critical patent/CN1505506A/zh
Application granted granted Critical
Publication of CN1250215C publication Critical patent/CN1250215C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
CNB028089170A 2001-02-27 2002-02-21 用于预防或治疗双相性精神障碍的氨基甲酸酯化合物 Expired - Fee Related CN1250215C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27168101P 2001-02-27 2001-02-27
US60/271,681 2001-02-27
US10/081,766 US6562867B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder
US10/081,766 2002-02-21

Publications (2)

Publication Number Publication Date
CN1505506A CN1505506A (zh) 2004-06-16
CN1250215C true CN1250215C (zh) 2006-04-12

Family

ID=26765948

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028089170A Expired - Fee Related CN1250215C (zh) 2001-02-27 2002-02-21 用于预防或治疗双相性精神障碍的氨基甲酸酯化合物

Country Status (26)

Country Link
US (1) US6562867B2 (enExample)
EP (1) EP1408953B1 (enExample)
JP (1) JP4276837B2 (enExample)
KR (1) KR100946944B1 (enExample)
CN (1) CN1250215C (enExample)
AT (1) ATE324108T1 (enExample)
BR (1) BR0207644A (enExample)
CA (1) CA2439475C (enExample)
CY (1) CY1105330T1 (enExample)
CZ (1) CZ20032300A3 (enExample)
DE (1) DE60210976T2 (enExample)
DK (1) DK1408953T3 (enExample)
ES (1) ES2262801T3 (enExample)
HU (1) HUP0303243A3 (enExample)
IL (1) IL157590A0 (enExample)
MX (1) MXPA03007717A (enExample)
MY (1) MY129304A (enExample)
NO (1) NO20033802L (enExample)
NZ (1) NZ527988A (enExample)
PL (1) PL364638A1 (enExample)
PT (1) PT1408953E (enExample)
RS (1) RS50677B (enExample)
RU (1) RU2300372C2 (enExample)
TW (1) TWI250872B (enExample)
WO (1) WO2002067921A1 (enExample)
ZA (1) ZA200307465B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1250213C (zh) * 2000-07-21 2006-04-12 奥索-麦克尼尔药品公司 用于预防或治疗神经性疼痛和丛集性头痛及有或没有先兆的偏头痛的氨基甲酸酯化合物
CN1503665A (zh) * 2001-02-27 2004-06-09 ����-������ҩƷ��˾ 用于预防或治疗焦虑症的氨基甲酸酯化合物
PT1383489E (pt) * 2001-02-27 2007-06-21 Ortho Mcneil Pharm Inc Compostos carbamato para utilização na prevenção ou tratamento de distúrbios neurodegenerativos
DE60232796D1 (de) 2001-07-16 2009-08-13 Ortho Mcneil Pharm Inc Carbamate verbindungen zur vorbeugung oder behandlung von neuropathischen schmerzen
DK1809273T3 (da) * 2004-09-16 2010-08-02 Janssen Pharmaceutica Nv Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese
RU2417077C2 (ru) 2005-06-08 2011-04-27 Ск Холдингз Ко., Лтд. Способ лечения чрезмерной дневной сонливости (варианты)
US20070021501A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods of treating epileptogenesis
JP2010508355A (ja) * 2006-10-30 2010-03-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 鬱病を処置する方法
EA200970435A1 (ru) * 2006-10-31 2009-10-30 Янссен Фармацевтика, Н. В. Лечение общих расстройств развития
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CN105189450B (zh) * 2013-03-12 2019-09-13 比皮艾思药物研发有限公司 氨基甲酸苯酯化合物及包含该化合物的用于预防或治疗精神障碍的组合物
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
KR102635938B1 (ko) * 2016-12-14 2024-02-13 에스케이바이오팜 주식회사 양극성 장애의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
MY203401A (en) 2017-06-02 2024-06-26 Jazz Pharmaceuticals Ireland Ltd Methods and compositions for treating excessive sleepiness
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
HU219911B (hu) * 1994-06-16 2001-09-28 Pfizer Inc. Pirazolo-piridin-származékok, alkalmazásuk és ezeket tartalmazó gyógyászati készítmények
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
YU67803A (sh) 2006-08-17
TWI250872B (en) 2006-03-11
ES2262801T3 (es) 2006-12-01
WO2002067921A1 (en) 2002-09-06
RS50677B (sr) 2010-06-30
MY129304A (en) 2007-03-30
KR20030087010A (ko) 2003-11-12
EP1408953A1 (en) 2004-04-21
CZ20032300A3 (cs) 2005-01-12
KR100946944B1 (ko) 2010-03-15
JP2004533415A (ja) 2004-11-04
CY1105330T1 (el) 2010-03-03
NO20033802L (no) 2003-10-22
RU2003128997A (ru) 2005-03-20
IL157590A0 (en) 2004-03-28
HUP0303243A2 (hu) 2004-01-28
CN1505506A (zh) 2004-06-16
JP4276837B2 (ja) 2009-06-10
US6562867B2 (en) 2003-05-13
US20020198257A1 (en) 2002-12-26
RU2300372C2 (ru) 2007-06-10
HUP0303243A3 (en) 2012-07-30
DE60210976D1 (de) 2006-06-01
PT1408953E (pt) 2006-07-31
NO20033802D0 (no) 2003-08-26
BR0207644A (pt) 2004-03-09
MXPA03007717A (es) 2005-11-08
NZ527988A (en) 2006-01-27
ZA200307465B (en) 2005-03-17
CA2439475C (en) 2010-05-18
DK1408953T3 (da) 2006-08-21
ATE324108T1 (de) 2006-05-15
PL364638A1 (en) 2004-12-13
HK1063436A1 (en) 2004-12-31
CA2439475A1 (en) 2002-09-06
DE60210976T2 (de) 2007-05-24
EP1408953B1 (en) 2006-04-26

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Granted publication date: 20060412

Termination date: 20120221