CY1105330T1 - Καρβαμιδικα παραγωγα για χρηση στην προληψη ή την αγωγη της διπολικης διαταραχης - Google Patents
Καρβαμιδικα παραγωγα για χρηση στην προληψη ή την αγωγη της διπολικης διαταραχηςInfo
- Publication number
- CY1105330T1 CY1105330T1 CY20061100844T CY061100844T CY1105330T1 CY 1105330 T1 CY1105330 T1 CY 1105330T1 CY 20061100844 T CY20061100844 T CY 20061100844T CY 061100844 T CY061100844 T CY 061100844T CY 1105330 T1 CY1105330 T1 CY 1105330T1
- Authority
- CY
- Cyprus
- Prior art keywords
- alkyl
- prevention
- treatment
- bipolar disorder
- phenyl
- Prior art date
Links
- 208000020925 Bipolar disease Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 150000003672 ureas Chemical class 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σε μία μέθοδο για την πρόληψη ή την αγωγή της διπολικής διαταραχής περιλαμβάνουσα τη χορήγηση σε ένα άτομο το οποίο την έχει ανάγκη μίας θεραπευτικά αποτελεσματικής ποσότητος μίας ενώσεως Τύπου (I): Τύπος (I). όπου το φαινύλιο είναι υποκατασταθέν στο Χ με ένα έως πέντε άτομα αλογόνου επιλεγόμενα από την ομάδα την αποτελούμενη από φθόριο, χλώριο, βρώμιο και ιώδιο· και τα R1 και R2 επιλέγονται ανεξάρτητα από την ομάδα την αποτελούμενη από υδρογόνο και αλκύλιο με C1-C4˙ όπου το αλκύλιο με C1-C4 φέρει προαιρετικά υποκατάσταση με φαινύλιο (όπου το φαινύλιο φέρει προαιρετικά υποκατάσταση με υποκαταστάτες επιλεγόμενους ανεξάρτητα από την ομάδα την αποτελούμενη από αλογόνο, αλκύλιο με C1-C4, αλκοξύλιο με C1-C4, αμίνη, νιτροομάδα και κυάνιο).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27168101P | 2001-02-27 | 2001-02-27 | |
| US10/081,766 US6562867B2 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating bipolar disorder |
| PCT/US2002/005297 WO2002067921A1 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating bipolar disorder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1105330T1 true CY1105330T1 (el) | 2010-03-03 |
Family
ID=26765948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061100844T CY1105330T1 (el) | 2001-02-27 | 2006-06-21 | Καρβαμιδικα παραγωγα για χρηση στην προληψη ή την αγωγη της διπολικης διαταραχης |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6562867B2 (el) |
| EP (1) | EP1408953B1 (el) |
| JP (1) | JP4276837B2 (el) |
| KR (1) | KR100946944B1 (el) |
| CN (1) | CN1250215C (el) |
| AT (1) | ATE324108T1 (el) |
| BR (1) | BR0207644A (el) |
| CA (1) | CA2439475C (el) |
| CY (1) | CY1105330T1 (el) |
| CZ (1) | CZ20032300A3 (el) |
| DE (1) | DE60210976T2 (el) |
| DK (1) | DK1408953T3 (el) |
| ES (1) | ES2262801T3 (el) |
| HK (1) | HK1063436A1 (el) |
| HU (1) | HUP0303243A3 (el) |
| IL (1) | IL157590A0 (el) |
| MX (1) | MXPA03007717A (el) |
| MY (1) | MY129304A (el) |
| NO (1) | NO20033802L (el) |
| NZ (1) | NZ527988A (el) |
| PL (1) | PL364638A1 (el) |
| PT (1) | PT1408953E (el) |
| RS (1) | RS50677B (el) |
| RU (1) | RU2300372C2 (el) |
| TW (1) | TWI250872B (el) |
| WO (1) | WO2002067921A1 (el) |
| ZA (1) | ZA200307465B (el) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100792814B1 (ko) * | 2000-07-21 | 2008-01-14 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 신경병증 통증 및 군발성 및 편두통성 두통-관련 통증의예방 또는 치료를 위해 사용하기 위한 카바메이트 화합물 |
| EP1383489B1 (en) * | 2001-02-27 | 2007-05-09 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating neurodegenerative disorders |
| CN1503665A (zh) | 2001-02-27 | 2004-06-09 | ����-������ҩƷ��˾ | 用于预防或治疗焦虑症的氨基甲酸酯化合物 |
| BR0211244A (pt) | 2001-07-16 | 2004-07-27 | Ortho Mcneil Pharm Inc | Compostos de carbamato para uso na prevenção ou tratamento de dor neuropática e dor associada com cefaléia em salvas e enxaqueca |
| NZ553813A (en) * | 2004-09-16 | 2010-09-30 | Janssen Pharmaceutica Nv | Use of 2-phenyl-1, 2-ethanediol-(DI) carbamates for treating epileptogenesis and epilepsy |
| WO2006133393A1 (en) | 2005-06-08 | 2006-12-14 | Sk Holdings Co., Ltd. | Treatment of sleep-wake disorders |
| US20070021501A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods of treating epileptogenesis |
| MX2009004770A (es) * | 2006-10-30 | 2009-08-17 | Janssen Pharmaceutica Nv | Compuestos de carbamato para usarse en el tratamiento de la depresion. |
| WO2008054984A1 (en) * | 2006-10-31 | 2008-05-08 | Janssen Pharmaceutica, N.V. | Treatment of pervasive developmental disorders |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| US9457003B2 (en) * | 2013-03-12 | 2016-10-04 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compound and a composition for preventing or treating a nerve gas-induced disease comprising the same |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| CA3046297A1 (en) * | 2016-12-14 | 2018-06-21 | Sk Biopharmaceuticals Co., Ltd. | Use of carbamate compounds for prevention, alleviation or treatment of bipolar disorder |
| US10959976B2 (en) | 2017-06-02 | 2021-03-30 | Jazz Pharmaceuticals Ireland Limited | Methods and compositions for treating excessive sleepiness |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3278380A (en) * | 1962-02-06 | 1966-10-11 | Armour Pharma | Methods of calming employing diphenyl hydroxy carbamate compounds |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
-
2002
- 2002-02-21 CN CNB028089170A patent/CN1250215C/zh not_active Expired - Fee Related
- 2002-02-21 DE DE60210976T patent/DE60210976T2/de not_active Expired - Lifetime
- 2002-02-21 NZ NZ527988A patent/NZ527988A/en unknown
- 2002-02-21 DK DK02724984T patent/DK1408953T3/da active
- 2002-02-21 CA CA2439475A patent/CA2439475C/en not_active Expired - Fee Related
- 2002-02-21 EP EP02724984A patent/EP1408953B1/en not_active Expired - Lifetime
- 2002-02-21 MX MXPA03007717A patent/MXPA03007717A/es active IP Right Grant
- 2002-02-21 BR BR0207644-6A patent/BR0207644A/pt not_active Application Discontinuation
- 2002-02-21 RU RU2003128997/14A patent/RU2300372C2/ru active
- 2002-02-21 RS YUP-678/03A patent/RS50677B/sr unknown
- 2002-02-21 PT PT02724984T patent/PT1408953E/pt unknown
- 2002-02-21 CZ CZ20032300A patent/CZ20032300A3/cs unknown
- 2002-02-21 KR KR1020037011296A patent/KR100946944B1/ko active IP Right Grant
- 2002-02-21 US US10/081,766 patent/US6562867B2/en not_active Expired - Lifetime
- 2002-02-21 PL PL02364638A patent/PL364638A1/xx not_active Application Discontinuation
- 2002-02-21 JP JP2002567288A patent/JP4276837B2/ja not_active Expired - Lifetime
- 2002-02-21 ES ES02724984T patent/ES2262801T3/es not_active Expired - Lifetime
- 2002-02-21 WO PCT/US2002/005297 patent/WO2002067921A1/en active IP Right Grant
- 2002-02-21 IL IL15759002A patent/IL157590A0/xx not_active IP Right Cessation
- 2002-02-21 HU HU0303243A patent/HUP0303243A3/hu unknown
- 2002-02-21 AT AT02724984T patent/ATE324108T1/de active
- 2002-02-27 TW TW091103500A patent/TWI250872B/zh active
- 2002-02-27 MY MYPI20020691A patent/MY129304A/en unknown
-
2003
- 2003-08-26 NO NO20033802A patent/NO20033802L/no not_active Application Discontinuation
- 2003-09-25 ZA ZA200307465A patent/ZA200307465B/en unknown
-
2004
- 2004-08-20 HK HK04106261A patent/HK1063436A1/xx not_active IP Right Cessation
-
2006
- 2006-06-21 CY CY20061100844T patent/CY1105330T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1105330T1 (el) | Καρβαμιδικα παραγωγα για χρηση στην προληψη ή την αγωγη της διπολικης διαταραχης | |
| CY1107468T1 (el) | Καρβαμιδικες ενωσεις για χρηση στην προληψη ή την αγωγη διαταραχων του αγχους | |
| CY1111349T1 (el) | Καρβαμιδικες ενωσεις προς χρηση στη θεραπεια του πονου | |
| CY1106753T1 (el) | Καρβαμιδικαι ενωσεις δια χρησιν εις προληψιν ή νοσηλειαν νευροεκφυλιστικων διαταραχων | |
| CY1106924T1 (el) | Ενωσεις καρβαμικου για χρηση οσον αφορα την προληψη ή την αγωγη των διαταραχων κινησης | |
| CY1107199T1 (el) | Καρβαμικες ενωσεις για χρηση στη προληψη ή τη θεραπευτικη αντιμετωπιση της διπολικης διαταραχης | |
| CY1105344T1 (el) | Αμινουχα παραγωγα της διυδρο- 1,3,5 - τριαζινης και οι εφαρμογες τους στη θepαπευτικη | |
| CY1109886T1 (el) | Καινοφανεις ενωσεις ως αντι-φλεγμονωδεις, ανοσοτροποποιητικοι και αντι υπερπλαστικοι παραγοντες | |
| EA200800294A1 (ru) | Способы нейропротекции | |
| NO20071921L (no) | Fremgangsmater for behandling av epileptogenese og epilepsi | |
| CY1113171T1 (el) | Αντιφλεγμονωδεις παραγοντες | |
| EA200800295A1 (ru) | Способы лечения эпилептогенеза | |
| CY1109085T1 (el) | Νεα αλατα | |
| EA200700871A1 (ru) | Способы нейропротекции | |
| TR200401511T4 (tr) | Nöropatik ağrı ve baş ağrısı nöbetleri ve migren tipi baş ağrısı ile ilişkili ağrının önlenmesi veya tedavi edilmesinde kullanılan karbamat bileşikleri. | |
| CY1109429T1 (el) | Καρβαμιδικες ενωσεις για χρηση στην προληψη ή τη θεραπεια του πονου λογω νευροπαθειας | |
| BR0207829A (pt) | Composto de carbamato para uso na prevenção ou tratamento de distúrbios psicóticos | |
| CY1106038T1 (el) | Καρβαμικες ενωσεις για χρηση στην προληψη ή την αγωγη του νeυpοπαθους πονου και του πονου που συνδεεται με την ισταμινογενη κεφαλαλγια και την ημικρανια | |
| CY1110672T1 (el) | Χρηση των 2- φαινυλ-1,2-αιθανοδιολης- (δι) καρβαμικων για θεραπεια επιληπτογενεσης | |
| MY136733A (en) | Carbamate compounds for use in preventing or treating psychotic disorders |