EA200800295A1 - Способы лечения эпилептогенеза - Google Patents
Способы лечения эпилептогенезаInfo
- Publication number
- EA200800295A1 EA200800295A1 EA200800295A EA200800295A EA200800295A1 EA 200800295 A1 EA200800295 A1 EA 200800295A1 EA 200800295 A EA200800295 A EA 200800295A EA 200800295 A EA200800295 A EA 200800295A EA 200800295 A1 EA200800295 A1 EA 200800295A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- group
- groups
- alkyl
- phenyl
- epileptogenesis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Изобретение направлено на создание способа предупреждения, лечения, обращения, ингибирования или приостановки эпилептогенеза у субъекта, заключающегося во введении этому субъекту, нуждающемуся в этом, терапевтически эффективного количества соединения, выбранного из группы, состоящей из формулы (I) и формулы (II), или его фармацевтически приемлемых соли или сложного эфира, в которых фенил замещен в Х атомами галогена, от одного до пяти, выбранными из группы, состоящей из фтора, хлора, брома и йода, a R, R, R, R, Rи Rнезависимо выбраны из группы, состоящей из водорода и C-С-алкила, в которой C-С-алкил является, необязательно, замещенным фенилом (в которой фенил является, необязательно, замещенным заместителями, независимо выбранными из группы, состоящей из галогена, C-С-алкила, C-С-алкоксигруппы, аминогруппы, нитрогруппы и цианогруппы).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69862505P | 2005-07-12 | 2005-07-12 | |
| PCT/US2006/026277 WO2007008551A2 (en) | 2005-07-12 | 2006-07-07 | Use of 2-phenyl-l, 2-ethanedi0l-(di) carbamates for treating epileptogenesis and epilepsy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200800295A1 true EA200800295A1 (ru) | 2008-12-30 |
Family
ID=37637731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200800295A EA200800295A1 (ru) | 2005-07-12 | 2006-07-07 | Способы лечения эпилептогенеза |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070021501A1 (ru) |
| EP (1) | EP1906946A2 (ru) |
| JP (1) | JP2009501223A (ru) |
| KR (1) | KR20080028485A (ru) |
| CN (1) | CN101309680A (ru) |
| AR (1) | AR054550A1 (ru) |
| AU (1) | AU2006269462A1 (ru) |
| BR (1) | BRPI0613010A2 (ru) |
| CA (1) | CA2615127A1 (ru) |
| EA (1) | EA200800295A1 (ru) |
| EC (1) | ECSP088172A (ru) |
| IL (1) | IL188728A0 (ru) |
| NO (1) | NO20080739L (ru) |
| TW (1) | TW200744575A (ru) |
| WO (1) | WO2007008551A2 (ru) |
| ZA (1) | ZA200801402B (ru) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2307035T3 (da) * | 2008-05-16 | 2014-01-20 | Nono Inc | Anvendelse af en PSD-95 inhibitor ved behandlingen af epilepsi |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| JP6062077B2 (ja) | 2013-03-12 | 2017-01-18 | バイオ−ファーム ソリューションズ カンパニー リミテッド | 小児てんかん及びてんかん関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| KR102615486B1 (ko) * | 2015-08-24 | 2023-12-19 | 조게닉스 인터내셔널 리미티드 | 펜플루라민을 사용하여 레녹스-가스토 증후군을 치료하는 방법 |
| US10351519B2 (en) | 2016-02-29 | 2019-07-16 | Bio-Pharm Solutions Co., Ltd. | Sulfamate derivative compounds, processes for preparing them and their uses |
| US20190022166A1 (en) * | 2017-07-18 | 2019-01-24 | Creative Bio-Peptides Inc. | Oral anti-inflammatory peptides to treat epilepsy, seizures and cns disorders |
| CN109920550A (zh) * | 2018-12-25 | 2019-06-21 | 天津大学 | 一种基于dMRI研究青少年肌阵挛性癫痫的方法 |
| CN115501344A (zh) * | 2022-09-29 | 2022-12-23 | 重庆医科大学 | 一种铁螯合剂的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| US6104956A (en) * | 1996-05-31 | 2000-08-15 | Board Of Trustees Of Southern Illinois University | Methods of treating traumatic brain injury by vagus nerve stimulation |
| ATE244564T1 (de) * | 1999-02-09 | 2003-07-15 | Univ Virginia | Felbamat-derivate |
| AU2002242226B2 (en) * | 2001-02-27 | 2006-06-29 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating bipolar disorder |
| IL157590A0 (en) * | 2001-02-27 | 2004-03-28 | Ortho Mcneil Pharm Inc | Carbamate compounds for use in preventing or treating bipolar disorder |
-
2006
- 2006-07-06 US US11/481,626 patent/US20070021501A1/en not_active Abandoned
- 2006-07-07 WO PCT/US2006/026277 patent/WO2007008551A2/en active Application Filing
- 2006-07-07 CN CNA2006800333910A patent/CN101309680A/zh active Pending
- 2006-07-07 EP EP06786434A patent/EP1906946A2/en not_active Withdrawn
- 2006-07-07 KR KR1020087003269A patent/KR20080028485A/ko not_active Application Discontinuation
- 2006-07-07 BR BRPI0613010-0A patent/BRPI0613010A2/pt not_active IP Right Cessation
- 2006-07-07 JP JP2008521432A patent/JP2009501223A/ja not_active Withdrawn
- 2006-07-07 CA CA002615127A patent/CA2615127A1/en not_active Abandoned
- 2006-07-07 EA EA200800295A patent/EA200800295A1/ru unknown
- 2006-07-07 AU AU2006269462A patent/AU2006269462A1/en not_active Abandoned
- 2006-07-11 AR ARP060102976A patent/AR054550A1/es not_active Application Discontinuation
- 2006-07-11 TW TW095125162A patent/TW200744575A/zh unknown
-
2008
- 2008-01-10 IL IL188728A patent/IL188728A0/en unknown
- 2008-02-11 ZA ZA200801402A patent/ZA200801402B/xx unknown
- 2008-02-11 NO NO20080739A patent/NO20080739L/no not_active Application Discontinuation
- 2008-02-12 EC EC2008008172A patent/ECSP088172A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP088172A (es) | 2008-03-26 |
| CN101309680A (zh) | 2008-11-19 |
| IL188728A0 (en) | 2008-11-03 |
| CA2615127A1 (en) | 2007-01-18 |
| WO2007008551A3 (en) | 2008-06-19 |
| JP2009501223A (ja) | 2009-01-15 |
| AU2006269462A1 (en) | 2007-01-18 |
| US20070021501A1 (en) | 2007-01-25 |
| EP1906946A2 (en) | 2008-04-09 |
| NO20080739L (no) | 2008-04-10 |
| KR20080028485A (ko) | 2008-03-31 |
| BRPI0613010A2 (pt) | 2010-12-14 |
| ZA200801402B (en) | 2009-10-28 |
| WO2007008551A2 (en) | 2007-01-18 |
| AR054550A1 (es) | 2007-06-27 |
| TW200744575A (en) | 2007-12-16 |
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