DK2307035T3 - Anvendelse af en PSD-95 inhibitor ved behandlingen af epilepsi - Google Patents

Anvendelse af en PSD-95 inhibitor ved behandlingen af epilepsi

Info

Publication number
DK2307035T3
DK2307035T3 DK09747499.3T DK09747499T DK2307035T3 DK 2307035 T3 DK2307035 T3 DK 2307035T3 DK 09747499 T DK09747499 T DK 09747499T DK 2307035 T3 DK2307035 T3 DK 2307035T3
Authority
DK
Denmark
Prior art keywords
psd
epilepsy
inhibitor
treatment
Prior art date
Application number
DK09747499.3T
Other languages
English (en)
Inventor
James Gurd
Crystal Dykstra
Michael Tymianski
Original Assignee
Nono Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nono Inc filed Critical Nono Inc
Application granted granted Critical
Publication of DK2307035T3 publication Critical patent/DK2307035T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1787—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
DK09747499.3T 2008-05-16 2009-05-13 Anvendelse af en PSD-95 inhibitor ved behandlingen af epilepsi DK2307035T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5410908P 2008-05-16 2008-05-16
PCT/US2009/043831 WO2009140416A2 (en) 2008-05-16 2009-05-13 Treatment for epilepsy

Publications (1)

Publication Number Publication Date
DK2307035T3 true DK2307035T3 (da) 2014-01-20

Family

ID=41319319

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09747499.3T DK2307035T3 (da) 2008-05-16 2009-05-13 Anvendelse af en PSD-95 inhibitor ved behandlingen af epilepsi

Country Status (9)

Country Link
US (1) US9161965B2 (da)
EP (1) EP2307035B1 (da)
JP (2) JP6005357B2 (da)
CN (1) CN102088990A (da)
AU (1) AU2009246316B2 (da)
CA (1) CA2724483C (da)
DK (1) DK2307035T3 (da)
ES (1) ES2446306T3 (da)
WO (1) WO2009140416A2 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595297B2 (en) * 1999-06-02 2009-09-29 Michael Tymianski Method of reducing injury to mammalian cells
US20080216828A1 (en) 2007-03-09 2008-09-11 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
ES2446306T3 (es) 2008-05-16 2014-03-07 Nono Inc. Uso de un inhibidor de psd-95 tratamiento para la epilepsia
CA2739416C (en) 2008-09-03 2017-10-31 Arbor Vita Corporation Agents and methods for treatment of pain
US20140323924A1 (en) * 2013-04-26 2014-10-30 David J. Mishelevich Targeted optogenetic neuromodulation for treatment of clinical conditions
JP6502858B2 (ja) 2013-01-31 2019-04-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 正常状態及び罹患状態での脳動態を特徴づけるためのシステムおよび方法
PL3261640T3 (pl) * 2015-02-25 2022-10-31 The Regents Of The University Of California Agoniści 5ht do leczenia zaburzeń padaczkowych
EP3383429B1 (en) 2015-11-30 2020-10-14 INSERM - Institut National de la Santé et de la Recherche Médicale Nmdar antagonists for the treatment of tumor angiogenesis
JP2019522675A (ja) * 2016-04-27 2019-08-15 ▲拝▼西欧斯（北京）生物技▲術▼有限公司 興奮製神経毒性に関連した損傷の治療方法
DK3450448T3 (da) 2016-04-27 2021-06-07 Biocells Beijing Biotech Co Ltd Terapeutisk peptid til excitatorisk neurotoksicitets-relaterede skader
KR20190104531A (ko) 2016-12-09 2019-09-10 알렉스자 파마스티칼즈, 인크. 간질 치료 방법
BR112020000115A2 (pt) * 2017-07-05 2020-07-07 Biocells (Beijing) Biotech Co., Ltd. sais farmaceuticamente aceitáveis de polipeptídeos e uso dos mesmos
CN111132687B (zh) * 2017-09-30 2023-05-02 拜西欧斯（北京）生物技术有限公司 兴奋性神经毒性相关损伤的治疗肽组合物
CN111712252A (zh) 2017-12-13 2020-09-25 纽约州立大学研究基金会 用于治疗疼痛和提高疼痛敏感性的肽和其它药剂
KR20210065969A (ko) * 2018-09-27 2021-06-04 핀치 테라퓨틱스 홀딩스 엘엘씨 간질 및 관련 장애를 치료하기 위한 조성물 및 방법
CA3153099A1 (en) * 2019-09-17 2021-03-25 Zogenix International Limited Methods of treating epileptic patients with fenfluramine
CN110627877A (zh) * 2019-09-25 2019-12-31 成都奥达生物科技有限公司 一种psd-95抑制剂
CN111285923B (zh) * 2020-03-05 2023-02-03 成都奥达生物科技有限公司 一种psd-95抑制剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060148711A1 (en) * 1999-05-14 2006-07-06 Arbor Vita Corporation Molecular interactions in neurons
US20050019841A1 (en) * 1999-05-14 2005-01-27 Arbor Vita Corporation Modulation of signaling pathways
US7595297B2 (en) * 1999-06-02 2009-09-29 Michael Tymianski Method of reducing injury to mammalian cells
US20050282743A1 (en) * 2001-08-03 2005-12-22 Arbor Vita Corporation Molecular interactions in cells
US20090075377A1 (en) * 2001-08-03 2009-03-19 Arbor Vita Corporation Molecular interactions in cells
EP1709084A4 (en) * 2003-12-23 2008-05-28 Nono Inc POLYPEPTIDES FOR MODULATING BINDING OF TRP-CHANNEL PROTEINS AND TRP-ASSOCIATED PROTEINS
WO2005097090A2 (en) * 2004-04-05 2005-10-20 Icos Corporation AGENTS THAT DISRUPT PSD95 - nNOS INTERACTION, COMPOSITIONS CONTAINING THE SAME, AND THERAPEUTIC USES THEREOF
CA2613012A1 (en) * 2005-06-23 2007-01-04 Arbor Vita Corporation Methods and compositions for modulating cox
US20070021501A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods of treating epileptogenesis
AU2006332535B2 (en) * 2005-12-30 2013-03-14 Nono Inc. Small molecule inhibitors of PDZ interactions
US8633160B2 (en) * 2005-12-30 2014-01-21 Nono Inc. Small molecule inhibitors of PDZ interactions
EP1884521A1 (en) * 2006-07-31 2008-02-06 Xigen S.A. Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins
US8288345B2 (en) * 2007-03-02 2012-10-16 Nono, Inc. Treating stroke and other diseases without inhibiting N-type calcium channels
US8008253B2 (en) * 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
US8080518B2 (en) * 2007-12-05 2011-12-20 Arbor Vita Corporation Co-administration of an agent linked to an internalization peptide with an anti-inflammatory
ES2446306T3 (es) 2008-05-16 2014-03-07 Nono Inc. Uso de un inhibidor de psd-95 tratamiento para la epilepsia
CA2739416C (en) * 2008-09-03 2017-10-31 Arbor Vita Corporation Agents and methods for treatment of pain

Also Published As

Publication number Publication date
EP2307035A4 (en) 2012-04-11
AU2009246316B2 (en) 2014-06-19
JP2011520900A (ja) 2011-07-21
CA2724483A1 (en) 2009-11-19
WO2009140416A2 (en) 2009-11-19
AU2009246316A1 (en) 2009-11-19
EP2307035B1 (en) 2013-12-04
JP2016199553A (ja) 2016-12-01
JP6005357B2 (ja) 2016-10-12
US20100160240A1 (en) 2010-06-24
ES2446306T3 (es) 2014-03-07
CA2724483C (en) 2018-01-02
CN102088990A (zh) 2011-06-08
US9161965B2 (en) 2015-10-20
EP2307035A2 (en) 2011-04-13
WO2009140416A3 (en) 2010-01-14

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