|
WO2002076925A2
(en)
*
|
2001-03-23 |
2002-10-03 |
Eli Lilly And Company |
Non-imidazole aryl alkylamines compounds as histamine h3 receptor antagonists, preparation and therapeutic uses
|
|
US6825198B2
(en)
*
|
2001-06-21 |
2004-11-30 |
Pfizer Inc |
5-HT receptor ligands and uses thereof
|
|
AU2003213184A1
(en)
|
2002-02-22 |
2003-09-09 |
Pharmacia And Upjohn Company |
Pyridyl sulfone derivatives as 5-ht receptor antagonists
|
|
US7314937B2
(en)
|
2002-03-21 |
2008-01-01 |
Eli Lilly And Company |
Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses
|
|
SE0201544D0
(sv)
*
|
2002-05-17 |
2002-05-17 |
Biovitrum Ab |
Novel compounds and thier use
|
|
US6989392B2
(en)
|
2002-06-18 |
2006-01-24 |
Abbott Laboratories |
2-Aminoquinolines as melanin concentrating hormone receptor antagonists
|
|
MXPA04012711A
(es)
*
|
2002-06-19 |
2005-03-23 |
Biovitrum Ab |
Nuevos compuestos, su uso y preparacion.
|
|
US7226925B2
(en)
|
2002-06-19 |
2007-06-05 |
Biovitrum Ab |
Compounds, their use and preparation
|
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
|
GB0215775D0
(en)
*
|
2002-07-06 |
2002-08-14 |
Astex Technology Ltd |
Pharmaceutical compounds
|
|
EP1599468B1
(en)
|
2003-01-14 |
2007-10-03 |
Arena Pharmaceuticals, Inc. |
1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
DE602004013938D1
(de)
*
|
2003-01-29 |
2008-07-03 |
Asterand Uk Ltd |
Hemmstoffe des ep4-rezeptors
|
|
CL2004000826A1
(es)
*
|
2003-04-25 |
2005-03-04 |
Pfizer |
Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129
|
|
AR045047A1
(es)
|
2003-07-11 |
2005-10-12 |
Arena Pharm Inc |
Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
|
|
AR045697A1
(es)
|
2003-07-14 |
2005-11-09 |
Arena Pharm Inc |
Aril y heteroaril derivados fusionados como moduladores del metabolismo y la prevencion y tratamiento de trastornos relacionados con el mismo
|
|
CA2551037A1
(en)
|
2003-09-22 |
2005-03-31 |
Banyu Pharmaceutical Co., Ltd. |
Novel piperidine derivative
|
|
WO2005033105A2
(en)
*
|
2003-09-30 |
2005-04-14 |
Amgen Inc. |
Vanilloid receptor ligands and their use in treatments
|
|
JP4529116B2
(ja)
*
|
2003-10-16 |
2010-08-25 |
東レ・ファインケミカル株式会社 |
高純度トリチルピペラジン誘導体の製造方法
|
|
WO2005053688A1
(en)
|
2003-11-26 |
2005-06-16 |
Alcon, Inc. |
Substituted furo[2,3-g] indazoles for the treatment of glaucoma
|
|
US7338972B1
(en)
|
2003-12-15 |
2008-03-04 |
Alcon, Inc. |
Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
|
|
US20080194574A1
(en)
*
|
2003-12-16 |
2008-08-14 |
Axxima Pharmaceuticals Ag |
Pyrazine Derivatives As Effective Compounds Against Infectious Diseases
|
|
WO2005097127A2
(en)
|
2004-04-02 |
2005-10-20 |
Merck & Co., Inc. |
Method of treating men with metabolic and anthropometric disorders
|
|
EP2248524A3
(en)
|
2004-08-25 |
2011-03-09 |
Takeda Pharmaceutical Company Limited |
Preventives/remedies for stress urinary incontinence and method of screening the same
|
|
CA2584806C
(en)
|
2004-11-01 |
2014-06-17 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and related disorders
|
|
AP2007004144A0
(en)
|
2005-03-31 |
2007-08-31 |
Pfizer Prod Inc |
Cyclopentapyridine and tetrahydroquinoline derivatives
|
|
US7737155B2
(en)
|
2005-05-17 |
2010-06-15 |
Schering Corporation |
Nitrogen-containing heterocyclic compounds and methods of use thereof
|
|
ES2574014T3
(es)
|
2005-05-30 |
2016-06-14 |
Msd K.K. |
Derivado de piperidina novedoso
|
|
AU2006277253A1
(en)
|
2005-08-10 |
2007-02-15 |
Msd K.K. |
Pyridone compound
|
|
EP2330125A3
(en)
|
2005-08-11 |
2012-12-12 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
|
AU2006279680B2
(en)
|
2005-08-11 |
2012-12-06 |
Amylin Pharmaceuticals, Llc |
Hybrid polypeptides with selectable properties
|
|
WO2007024004A1
(ja)
|
2005-08-24 |
2007-03-01 |
Banyu Pharmaceutical Co., Ltd. |
フェニルピリドン誘導体
|
|
AU2006288153A1
(en)
|
2005-09-07 |
2007-03-15 |
Msd K.K. |
Bicyclic aromatic substituted pyridone derivative
|
|
KR20080048502A
(ko)
|
2005-09-29 |
2008-06-02 |
머크 앤드 캄파니 인코포레이티드 |
멜라노코르틴-4 수용체 조절제로서의 아실화스피로피페리딘 유도체
|
|
KR20080059233A
(ko)
|
2005-10-21 |
2008-06-26 |
노파르티스 아게 |
레닌 억제제, 및 항이상지질혈증제 및/또는 항비만제의조합물
|
|
WO2007049798A1
(ja)
|
2005-10-27 |
2007-05-03 |
Banyu Pharmaceutical Co., Ltd. |
新規ベンゾオキサチイン誘導体
|
|
BRPI0618354B8
(pt)
|
2005-11-10 |
2021-05-25 |
Banyu Pharma Co Ltd |
composto e seu uso, composição farmacêutica, preventivo ou remédio
|
|
WO2007132841A1
(ja)
|
2006-05-16 |
2007-11-22 |
Takeda Pharmaceutical Company Limited |
縮合複素環化合物およびその用途
|
|
EP2698157B1
(en)
|
2006-09-22 |
2015-05-20 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
|
US20090247560A1
(en)
|
2006-09-28 |
2009-10-01 |
Banyu Pharmaceutical Co., Ltd. |
Diaryl ketimine derivative
|
|
EP2118279B1
(en)
|
2007-01-16 |
2017-11-22 |
Ipintl, Llc |
Novel composition for treating metabolic syndrome
|
|
WO2008120653A1
(ja)
|
2007-04-02 |
2008-10-09 |
Banyu Pharmaceutical Co., Ltd. |
インドールジオン誘導体
|
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
|
CN103601792B
(zh)
|
2007-06-04 |
2016-06-29 |
协同医药品公司 |
有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂
|
|
JP5520051B2
(ja)
|
2007-11-15 |
2014-06-11 |
武田薬品工業株式会社 |
縮合ピリジン誘導体およびその用途
|
|
WO2009110510A1
(ja)
|
2008-03-06 |
2009-09-11 |
萬有製薬株式会社 |
アルキルアミノピリジン誘導体
|
|
CA2717384A1
(en)
|
2008-03-28 |
2009-10-01 |
Banyu Pharmaceutical Co., Ltd. |
Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
|
|
CA2666036C
(en)
|
2008-05-16 |
2017-09-12 |
Chien-Hung Chen |
Novel compositions and methods for treating hyperproliferative diseases
|
|
US20110071129A1
(en)
|
2008-06-19 |
2011-03-24 |
Makoto Ando |
Spirodiamine-diaryl ketoxime derivative
|
|
ES2624828T3
(es)
|
2008-07-16 |
2017-07-17 |
Synergy Pharmaceuticals Inc. |
Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
|
|
JPWO2010013595A1
(ja)
|
2008-07-30 |
2012-01-12 |
Msd株式会社 |
5員−5員又は5員−6員縮環シクロアルキルアミン誘導体
|
|
MX2011004258A
(es)
|
2008-10-22 |
2011-06-01 |
Merck Sharp & Dohme |
Derivados de bencimidazol ciclicos novedosos utiles como agentes anti-diabeticos.
|
|
BRPI0919876A8
(pt)
|
2008-10-30 |
2016-02-10 |
Merck Sharp & Dohme |
Composto, composição farmacêutica, uso de um composto, e, método para intensificar a qualidade do sono, para tratar insônia, e para tratar ou controlar obesidade em um paciente mamífero que necessita do mesmo.
|
|
CA2741672A1
(en)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
EP2379562A1
(en)
|
2008-12-16 |
2011-10-26 |
Schering Corporation |
Bicyclic pyranone derivatives as nicotinic acid receptor agonists
|
|
US20110245209A1
(en)
|
2008-12-16 |
2011-10-06 |
Schering Corporation |
Pyridopyrimidine derivatives and methods of use thereof
|
|
WO2011071136A1
(ja)
|
2009-12-11 |
2011-06-16 |
アステラス製薬株式会社 |
線維筋痛症治療剤
|
|
CA2786314A1
(en)
|
2010-02-25 |
2011-09-01 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
WO2012030953A1
(en)
|
2010-09-01 |
2012-03-08 |
Arena Pharmaceuticals, Inc. |
5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
AU2011305525B2
(en)
|
2010-09-22 |
2016-08-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the GPR119 receptor and the treatment of disorders related thereto
|
|
SG192941A1
(en)
|
2011-02-25 |
2013-09-30 |
Merck Sharp & Dohme |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
|
MX357121B
(es)
|
2011-03-01 |
2018-06-27 |
Synergy Pharmaceuticals Inc Star |
Proceso de preparacion de agonistas c de guanilato ciclasa.
|
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
|
JP6242810B2
(ja)
*
|
2011-12-28 |
2017-12-06 |
グローバル・ブラッド・セラピューティクス・インコーポレイテッドGlobal Blood Therapeutics,Inc. |
置換ベンズアルデヒド化合物および組織酸素化の増加におけるそれらの使用方法
|
|
WO2013102145A1
(en)
|
2011-12-28 |
2013-07-04 |
Global Blood Therapeutics, Inc. |
Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
|
|
MX2014014308A
(es)
*
|
2012-05-30 |
2015-02-12 |
Hoffmann La Roche |
Pirrolidino heterociclos.
|
|
KR20150036245A
(ko)
|
2012-08-02 |
2015-04-07 |
머크 샤프 앤드 돔 코포레이션 |
항당뇨병 트리시클릭 화합물
|
|
EP2970119B1
(en)
|
2013-03-14 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
|
US9486494B2
(en)
|
2013-03-15 |
2016-11-08 |
Synergy Pharmaceuticals, Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
|
MX379228B
(es)
|
2013-03-15 |
2025-03-10 |
Global Blood Therapeutics Inc |
Compuestos y usos de estos para la modulación de la hemoglobina.
|
|
CN105246477A
(zh)
|
2013-03-15 |
2016-01-13 |
全球血液疗法股份有限公司 |
化合物及其用于调节血红蛋白的用途
|
|
US8952171B2
(en)
|
2013-03-15 |
2015-02-10 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
EA037091B1
(ru)
|
2013-03-15 |
2021-02-04 |
Глобал Блад Терапьютикс, Инк. |
Соединения и их применения для модуляции гемоглобина
|
|
WO2014151206A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
|
EP4424697A3
(en)
|
2013-06-05 |
2024-12-25 |
Bausch Health Ireland Limited |
Ultra-pure agonists of guanylate cyclase c, method of making and using same
|
|
WO2015066344A1
(en)
|
2013-11-01 |
2015-05-07 |
Arena Pharmaceuticals, Inc. |
5-ht2c receptor agonists and compositions and methods of use
|
|
CN114213390A
(zh)
|
2014-02-07 |
2022-03-22 |
全球血液疗法股份有限公司 |
一种化合物的结晶多晶型物
|
|
JP6769963B2
(ja)
|
2014-08-29 |
2020-10-14 |
ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ |
α−アミノ−β−カルボキシムコン酸セミアルデヒド脱炭酸酵素の阻害剤
|
|
CN116850181A
(zh)
|
2015-01-06 |
2023-10-10 |
艾尼纳制药公司 |
治疗与s1p1受体有关的病症的方法
|
|
AU2016284162A1
(en)
|
2015-06-22 |
2018-02-01 |
Arena Pharmaceuticals, Inc. |
Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(Compound1) for use in SIP1 receptor-associated disorders
|
|
FI3383392T3
(fi)
|
2015-12-04 |
2025-09-11 |
Global Blood Therapeutics Inc |
Annosteluohjelmat 2-hydroksi-6-((2-(1-isopropyyli-1h-pyratsol-5-yyli)pyridin-3-yyli)metoksi)bentsaldehydille
|
|
AU2017342083A1
(en)
|
2016-10-14 |
2019-04-11 |
Tes Pharma S.R.L. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
|
AU2018220521A1
(en)
|
2017-02-16 |
2019-09-05 |
Arena Pharmaceuticals, Inc. |
Compounds and methods for treatment of primary biliary cholangitis
|
|
WO2019131902A1
(ja)
|
2017-12-27 |
2019-07-04 |
武田薬品工業株式会社 |
腹圧性尿失禁および便失禁の治療薬
|
|
WO2019236757A1
(en)
|
2018-06-06 |
2019-12-12 |
Arena Pharmaceuticals, Inc. |
Methods of treating conditions related to the s1p1 receptor
|
|
WO2020072377A1
(en)
|
2018-10-01 |
2020-04-09 |
Global Blood Therapeutics, Inc. |
Modulators of hemoglobin for the treatment of sickle cell disease
|
|
CA3119509A1
(en)
|
2018-11-20 |
2020-05-28 |
Tes Pharma S.R.L |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxxylase
|
|
WO2020167706A1
(en)
|
2019-02-13 |
2020-08-20 |
Merck Sharp & Dohme Corp. |
5-alkyl pyrrolidine orexin receptor agonists
|
|
WO2020167701A1
(en)
|
2019-02-13 |
2020-08-20 |
Merck Sharp & Dohme Corp. |
Pyrrolidine orexin receptor agonists
|
|
US20220340546A1
(en)
*
|
2019-06-14 |
2022-10-27 |
Disarm Therapeutics, Inc. |
Inhibitors of sarm1
|
|
WO2021026047A1
(en)
|
2019-08-08 |
2021-02-11 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
|
PE20231384A1
(es)
|
2020-08-18 |
2023-09-12 |
Merck Sharp And Dohme Llc |
Agonistas de bicicloheptano pirrolidina de los receptores de orexina
|