JP2004532027A5 - - Google Patents
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- Publication number
- JP2004532027A5 JP2004532027A5 JP2002582264A JP2002582264A JP2004532027A5 JP 2004532027 A5 JP2004532027 A5 JP 2004532027A5 JP 2002582264 A JP2002582264 A JP 2002582264A JP 2002582264 A JP2002582264 A JP 2002582264A JP 2004532027 A5 JP2004532027 A5 JP 2004532027A5
- Authority
- JP
- Japan
- Prior art keywords
- reverse primer
- nucleic acid
- forward primer
- amplification product
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003729 nucleotide group Chemical group 0.000 claims 29
- 230000003321 amplification Effects 0.000 claims 27
- 238000003199 nucleic acid amplification method Methods 0.000 claims 27
- 239000002773 nucleotide Substances 0.000 claims 27
- 238000000034 method Methods 0.000 claims 26
- 150000007523 nucleic acids Chemical class 0.000 claims 26
- 239000000523 sample Substances 0.000 claims 23
- 108020004707 nucleic acids Proteins 0.000 claims 14
- 102000039446 nucleic acids Human genes 0.000 claims 14
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 9
- 230000000295 complement effect Effects 0.000 claims 8
- 241000700605 Viruses Species 0.000 claims 3
- 241000711549 Hepacivirus C Species 0.000 claims 2
- 241000725303 Human immunodeficiency virus Species 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 238000003752 polymerase chain reaction Methods 0.000 claims 2
- YZEUHQHUFTYLPH-UHFFFAOYSA-N 2-nitroimidazole Chemical compound [O-][N+](=O)C1=NC=CN1 YZEUHQHUFTYLPH-UHFFFAOYSA-N 0.000 claims 1
- WCKQPPQRFNHPRJ-UHFFFAOYSA-N 4-[[4-(dimethylamino)phenyl]diazenyl]benzoic acid Chemical compound C1=CC(N(C)C)=CC=C1N=NC1=CC=C(C(O)=O)C=C1 WCKQPPQRFNHPRJ-UHFFFAOYSA-N 0.000 claims 1
- 241000700721 Hepatitis B virus Species 0.000 claims 1
- RDXLYGJSWZYTFJ-UHFFFAOYSA-N Niridazole Chemical compound S1C([N+](=O)[O-])=CN=C1N1C(=O)NCC1 RDXLYGJSWZYTFJ-UHFFFAOYSA-N 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- -1 anthroquinone Chemical compound 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- FDZZZRQASAIRJF-UHFFFAOYSA-M malachite green Chemical compound [Cl-].C1=CC(N(C)C)=CC=C1C(C=1C=CC=CC=1)=C1C=CC(=[N+](C)C)C=C1 FDZZZRQASAIRJF-UHFFFAOYSA-M 0.000 claims 1
- 229940107698 malachite green Drugs 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 229960005130 niridazole Drugs 0.000 claims 1
- 238000010223 real-time analysis Methods 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28433401P | 2001-04-17 | 2001-04-17 | |
| PCT/US2002/012035 WO2002083927A2 (en) | 2001-04-17 | 2002-04-17 | Universal multi-variant detection system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004532027A JP2004532027A (ja) | 2004-10-21 |
| JP2004532027A5 true JP2004532027A5 (https=) | 2005-12-22 |
| JP4271944B2 JP4271944B2 (ja) | 2009-06-03 |
Family
ID=23089805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582264A Expired - Fee Related JP4271944B2 (ja) | 2001-04-17 | 2002-04-17 | ユニバーサルマルチ変異体検出システム |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US7348164B2 (https=) |
| EP (1) | EP1390544B1 (https=) |
| JP (1) | JP4271944B2 (https=) |
| KR (1) | KR20040018354A (https=) |
| CN (1) | CN1279182C (https=) |
| AT (1) | ATE346958T1 (https=) |
| AU (1) | AU2002307359B2 (https=) |
| CA (1) | CA2444174A1 (https=) |
| DE (1) | DE60216445T2 (https=) |
| ES (1) | ES2278043T3 (https=) |
| WO (1) | WO2002083927A2 (https=) |
| ZA (1) | ZA200308906B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2444174A1 (en) * | 2001-04-17 | 2002-10-24 | The New York Blood Center, Inc. | Universal multi-variant detection system |
| EP2251441B1 (en) * | 2004-02-10 | 2013-05-08 | F. Hoffmann-La Roche AG | Detection of parvovirus B19 |
| AU2011253599B2 (en) * | 2004-09-30 | 2013-12-12 | Gen-Probe Incorporated | Assay for detecting and quantifying HIV-1 |
| DK2975139T3 (da) * | 2004-09-30 | 2019-12-09 | Gen Probe Inc | Assay til at detektere og kvantificere hiv-1 |
| US7833716B2 (en) | 2006-06-06 | 2010-11-16 | Gen-Probe Incorporated | Tagged oligonucleotides and their use in nucleic acid amplification methods |
| EP3095873B1 (en) | 2006-12-21 | 2018-04-18 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| WO2010105275A2 (en) | 2009-03-13 | 2010-09-16 | Cornell University | Method to assess human allograft status from microrna expression levels |
| US8512955B2 (en) | 2009-07-01 | 2013-08-20 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| US9746479B2 (en) | 2010-03-09 | 2017-08-29 | Cornell University | Methods and compositions to predict and detect acute rejection |
| US9932628B2 (en) | 2012-07-27 | 2018-04-03 | Gen-Probe Incorporated | Dual reference calibration method and system for quantifying polynucleotides |
| KR101377824B1 (ko) * | 2012-11-19 | 2014-04-01 | 가톨릭대학교 산학협력단 | 수인성 바이러스 검출용 프라이머 및 이를 포함하는 검출 키트 |
| CN103901000B (zh) * | 2012-12-26 | 2016-09-28 | 江南大学 | 一种基于荧光共振能量转移检测伏马菌毒素b1的方法 |
| US9758828B2 (en) | 2013-01-31 | 2017-09-12 | Cornell University | Methods to detect, treat and prevent acute cellular rejection in kidney allografts |
| US9982301B2 (en) | 2014-01-07 | 2018-05-29 | Cornell University | Urine mRNA profile and acute dysfunction of kidney allograft |
| US20170032100A1 (en) | 2014-04-10 | 2017-02-02 | The Trustees Of The University Of Pennslyvania | Use of micro-ribonucleic acid (mirna) to diagnose transplant rejection and tolerance of immunosuppression therapy |
| CA2978696A1 (en) | 2015-02-03 | 2016-08-11 | The Trustees Of The University Of Pennsylvania | Novel methods for early identification of bone healing ability in injured patients |
| WO2017212023A1 (en) * | 2016-06-10 | 2017-12-14 | Roche Diagnostics Gmbh | Compositions and methods for detection of hepatitis c virus genotype 3 |
| CN110699353A (zh) * | 2019-07-26 | 2020-01-17 | 安徽大学 | 一种靶向端粒的核酸探针 |
| CN120265769A (zh) * | 2023-10-08 | 2025-07-04 | 迈克生物股份有限公司 | 引物探针组合物、核酸检测方法及应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US6007983A (en) * | 1995-12-22 | 1999-12-28 | Visible Genetics Inc. | Method and kit for evaluation of HIV mutations |
| AU713667B2 (en) * | 1996-04-12 | 1999-12-09 | Phri Properties, Inc. | Detection probes, kits and assays |
| US6117635A (en) * | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
| WO2000068436A1 (en) * | 1999-05-07 | 2000-11-16 | Nationales Zentrum Für Retroviren | Detection system for human immunodeficiency virus based on nucleic acid amplification |
| US6759193B2 (en) | 1999-07-28 | 2004-07-06 | The Government Of The Republic Of Singapore | Detection of human hepatitis B virus surface antigen mutants by specific amplification and its application on gene chip |
| CA2444174A1 (en) * | 2001-04-17 | 2002-10-24 | The New York Blood Center, Inc. | Universal multi-variant detection system |
-
2002
- 2002-04-17 CA CA002444174A patent/CA2444174A1/en not_active Abandoned
- 2002-04-17 US US10/399,843 patent/US7348164B2/en not_active Expired - Lifetime
- 2002-04-17 ES ES02762133T patent/ES2278043T3/es not_active Expired - Lifetime
- 2002-04-17 JP JP2002582264A patent/JP4271944B2/ja not_active Expired - Fee Related
- 2002-04-17 CN CNB028102681A patent/CN1279182C/zh not_active Expired - Fee Related
- 2002-04-17 WO PCT/US2002/012035 patent/WO2002083927A2/en not_active Ceased
- 2002-04-17 DE DE60216445T patent/DE60216445T2/de not_active Expired - Lifetime
- 2002-04-17 AU AU2002307359A patent/AU2002307359B2/en not_active Ceased
- 2002-04-17 EP EP02762133A patent/EP1390544B1/en not_active Expired - Lifetime
- 2002-04-17 AT AT02762133T patent/ATE346958T1/de not_active IP Right Cessation
- 2002-04-17 KR KR10-2003-7013577A patent/KR20040018354A/ko not_active Abandoned
-
2003
- 2003-11-14 ZA ZA200308906A patent/ZA200308906B/en unknown
-
2008
- 2008-01-28 US US12/011,603 patent/US8192939B2/en not_active Expired - Fee Related
-
2012
- 2012-04-26 US US13/457,123 patent/US20120258446A1/en not_active Abandoned
-
2013
- 2013-04-04 US US13/857,069 patent/US20130288231A1/en not_active Abandoned
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