KR20040018354A - 범용 다수-변이체 검출 시스템 - Google Patents

범용 다수-변이체 검출 시스템 Download PDF

Info

Publication number
KR20040018354A
KR20040018354A KR10-2003-7013577A KR20037013577A KR20040018354A KR 20040018354 A KR20040018354 A KR 20040018354A KR 20037013577 A KR20037013577 A KR 20037013577A KR 20040018354 A KR20040018354 A KR 20040018354A
Authority
KR
South Korea
Prior art keywords
nucleic acid
reverse primer
sequence
forward primer
primer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
KR10-2003-7013577A
Other languages
English (en)
Korean (ko)
Inventor
린다 앤드루스
카멘 니콜라 니콜스
Original Assignee
더 뉴욕 블러드 센터, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 더 뉴욕 블러드 센터, 인코포레이티드 filed Critical 더 뉴욕 블러드 센터, 인코포레이티드
Publication of KR20040018354A publication Critical patent/KR20040018354A/ko
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • C12Q1/707Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Small-Scale Networks (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR10-2003-7013577A 2001-04-17 2002-04-17 범용 다수-변이체 검출 시스템 Abandoned KR20040018354A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28433401P 2001-04-17 2001-04-17
US60/284,334 2001-04-17
PCT/US2002/012035 WO2002083927A2 (en) 2001-04-17 2002-04-17 Universal multi-variant detection system

Publications (1)

Publication Number Publication Date
KR20040018354A true KR20040018354A (ko) 2004-03-03

Family

ID=23089805

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2003-7013577A Abandoned KR20040018354A (ko) 2001-04-17 2002-04-17 범용 다수-변이체 검출 시스템

Country Status (12)

Country Link
US (4) US7348164B2 (https=)
EP (1) EP1390544B1 (https=)
JP (1) JP4271944B2 (https=)
KR (1) KR20040018354A (https=)
CN (1) CN1279182C (https=)
AT (1) ATE346958T1 (https=)
AU (1) AU2002307359B2 (https=)
CA (1) CA2444174A1 (https=)
DE (1) DE60216445T2 (https=)
ES (1) ES2278043T3 (https=)
WO (1) WO2002083927A2 (https=)
ZA (1) ZA200308906B (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2444174A1 (en) * 2001-04-17 2002-10-24 The New York Blood Center, Inc. Universal multi-variant detection system
EP2251441B1 (en) * 2004-02-10 2013-05-08 F. Hoffmann-La Roche AG Detection of parvovirus B19
AU2011253599B2 (en) * 2004-09-30 2013-12-12 Gen-Probe Incorporated Assay for detecting and quantifying HIV-1
DK2975139T3 (da) * 2004-09-30 2019-12-09 Gen Probe Inc Assay til at detektere og kvantificere hiv-1
US7833716B2 (en) 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
EP3095873B1 (en) 2006-12-21 2018-04-18 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
WO2010105275A2 (en) 2009-03-13 2010-09-16 Cornell University Method to assess human allograft status from microrna expression levels
US8512955B2 (en) 2009-07-01 2013-08-20 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
US9746479B2 (en) 2010-03-09 2017-08-29 Cornell University Methods and compositions to predict and detect acute rejection
US9932628B2 (en) 2012-07-27 2018-04-03 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
KR101377824B1 (ko) * 2012-11-19 2014-04-01 가톨릭대학교 산학협력단 수인성 바이러스 검출용 프라이머 및 이를 포함하는 검출 키트
CN103901000B (zh) * 2012-12-26 2016-09-28 江南大学 一种基于荧光共振能量转移检测伏马菌毒素b1的方法
US9758828B2 (en) 2013-01-31 2017-09-12 Cornell University Methods to detect, treat and prevent acute cellular rejection in kidney allografts
US9982301B2 (en) 2014-01-07 2018-05-29 Cornell University Urine mRNA profile and acute dysfunction of kidney allograft
US20170032100A1 (en) 2014-04-10 2017-02-02 The Trustees Of The University Of Pennslyvania Use of micro-ribonucleic acid (mirna) to diagnose transplant rejection and tolerance of immunosuppression therapy
CA2978696A1 (en) 2015-02-03 2016-08-11 The Trustees Of The University Of Pennsylvania Novel methods for early identification of bone healing ability in injured patients
WO2017212023A1 (en) * 2016-06-10 2017-12-14 Roche Diagnostics Gmbh Compositions and methods for detection of hepatitis c virus genotype 3
CN110699353A (zh) * 2019-07-26 2020-01-17 安徽大学 一种靶向端粒的核酸探针
CN120265769A (zh) * 2023-10-08 2025-07-04 迈克生物股份有限公司 引物探针组合物、核酸检测方法及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US6007983A (en) * 1995-12-22 1999-12-28 Visible Genetics Inc. Method and kit for evaluation of HIV mutations
AU713667B2 (en) * 1996-04-12 1999-12-09 Phri Properties, Inc. Detection probes, kits and assays
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
WO2000068436A1 (en) * 1999-05-07 2000-11-16 Nationales Zentrum Für Retroviren Detection system for human immunodeficiency virus based on nucleic acid amplification
US6759193B2 (en) 1999-07-28 2004-07-06 The Government Of The Republic Of Singapore Detection of human hepatitis B virus surface antigen mutants by specific amplification and its application on gene chip
CA2444174A1 (en) * 2001-04-17 2002-10-24 The New York Blood Center, Inc. Universal multi-variant detection system

Also Published As

Publication number Publication date
US20130288231A1 (en) 2013-10-31
JP2004532027A (ja) 2004-10-21
AU2002307359B2 (en) 2007-09-13
ATE346958T1 (de) 2006-12-15
US7348164B2 (en) 2008-03-25
ES2278043T3 (es) 2007-08-01
WO2002083927A2 (en) 2002-10-24
ZA200308906B (en) 2004-11-23
HK1065825A1 (zh) 2005-03-04
EP1390544A2 (en) 2004-02-25
EP1390544A4 (en) 2004-07-14
DE60216445D1 (de) 2007-01-11
US20120258446A1 (en) 2012-10-11
CN1279182C (zh) 2006-10-11
US20110053138A1 (en) 2011-03-03
EP1390544B1 (en) 2006-11-29
JP4271944B2 (ja) 2009-06-03
WO2002083927A3 (en) 2003-03-20
US8192939B2 (en) 2012-06-05
US20040053284A1 (en) 2004-03-18
CN1509338A (zh) 2004-06-30
CA2444174A1 (en) 2002-10-24
DE60216445T2 (de) 2007-10-31

Similar Documents

Publication Publication Date Title
US8192939B2 (en) Universal multi-variant detection system
JP5205346B2 (ja) Hiv−1の増幅及び検出試薬
AU2002307359A1 (en) Universal multi-variant detection system
US10655190B2 (en) Compositions and methods for detection of Zika virus
US9080218B2 (en) HIV type and subtype detection
JP2020092721A (ja) ターゲット核酸検出のための二重プローブアッセイ
CA2913729C (en) Real-time pcr point mutation assays for detecting hiv-1 resistance to antiviral drugs
US20250340957A1 (en) Assays for the Detection of SARS-CoV2 Mutants
KR102653475B1 (ko) 코로나 바이러스 동시 검출용 조성물 및 검출 방법
WO2017164741A2 (en) Detection of zika virus nucleic acid
US20240240273A1 (en) Compositions and Methods for Detecting Hepatitis Delta Virus by a Dual-Target Assay
JP6956800B2 (ja) アデノウイルス、メタニューモウイルス、および/またはライノウイルス核酸を検出するための組成物、方法、およびキット
KR102741691B1 (ko) SARS-CoV-2 변이 선별용 다중 LAMP 조성물 및 이의 용도
US12421560B2 (en) Assays for the detection of SARS-CoV-2 mutants
JP2019524123A (ja) 核酸の増幅及び検出/定量の効率を改良するためのヘルパーオリゴヌクレオチド
AU2016202864B2 (en) Assay for detecting and quantifying HIV-1
HK1065825B (en) Universal multi-variant detection system

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20031017

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20070322

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20080430

Patent event code: PE09021S01D

E90F Notification of reason for final refusal
PE0902 Notice of grounds for rejection

Comment text: Final Notice of Reason for Refusal

Patent event date: 20081030

Patent event code: PE09021S02D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20090630

NORF Unpaid initial registration fee
PC1904 Unpaid initial registration fee