JP2004529890A5 - - Google Patents
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- Publication number
- JP2004529890A5 JP2004529890A5 JP2002569118A JP2002569118A JP2004529890A5 JP 2004529890 A5 JP2004529890 A5 JP 2004529890A5 JP 2002569118 A JP2002569118 A JP 2002569118A JP 2002569118 A JP2002569118 A JP 2002569118A JP 2004529890 A5 JP2004529890 A5 JP 2004529890A5
- Authority
- JP
- Japan
- Prior art keywords
- nicotine
- substrate layer
- layer
- skin
- methacrylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000010410 layer Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 11
- 229920001577 copolymer Polymers 0.000 claims 8
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 7
- 229960002715 nicotine Drugs 0.000 claims 7
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 7
- 239000000758 substrate Substances 0.000 claims 7
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 2
- -1 aluminum ions Chemical class 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims 1
- 229910052782 aluminium Inorganic materials 0.000 claims 1
- 239000012752 auxiliary agent Substances 0.000 claims 1
- 210000003169 central nervous system Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011241 protective layer Substances 0.000 claims 1
- 230000003014 reinforcing effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 231100000245 skin permeability Toxicity 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000010936 titanium Substances 0.000 claims 1
- 229910052719 titanium Inorganic materials 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10110391A DE10110391A1 (de) | 2001-03-03 | 2001-03-03 | Hochflexibles Nikotin transdermales therapeutisches System mit Nikotin als Wirkstoff |
| PCT/EP2002/001728 WO2002069940A2 (de) | 2001-03-03 | 2002-02-19 | Hochflexibles transdermales therapeutisches system mit nikotin als wirkstoff |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004529890A JP2004529890A (ja) | 2004-09-30 |
| JP2004529890A5 true JP2004529890A5 (https=) | 2006-08-03 |
Family
ID=7676278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002569118A Pending JP2004529890A (ja) | 2001-03-03 | 2002-02-19 | 活性成分としてのニコチンを有する可撓性の著しい皮膚透過性治療系 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8226974B2 (https=) |
| EP (1) | EP1372619B1 (https=) |
| JP (1) | JP2004529890A (https=) |
| KR (1) | KR100873257B1 (https=) |
| CN (1) | CN1330305C (https=) |
| AR (1) | AR035688A1 (https=) |
| AU (1) | AU2002308289B2 (https=) |
| BR (1) | BR0207738A (https=) |
| CA (1) | CA2440012C (https=) |
| CZ (1) | CZ20032379A3 (https=) |
| DE (1) | DE10110391A1 (https=) |
| ES (1) | ES2386886T3 (https=) |
| HU (1) | HUP0303311A3 (https=) |
| IL (2) | IL157692A0 (https=) |
| MX (1) | MXPA03007903A (https=) |
| NZ (1) | NZ527824A (https=) |
| PL (1) | PL205582B1 (https=) |
| RU (1) | RU2302856C2 (https=) |
| TW (1) | TWI264312B (https=) |
| WO (1) | WO2002069940A2 (https=) |
| ZA (1) | ZA200306194B (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE20321052U1 (de) * | 2002-05-28 | 2005-09-22 | LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH | Pflaster, enthaltend Fentanylum |
| BRPI0412752B8 (pt) * | 2003-07-24 | 2021-05-25 | Glaxosmithkline Llc | composição de filme de dissolução oral |
| RU2263503C1 (ru) * | 2004-04-23 | 2005-11-10 | Каш Тенгиз | Способ получения препарата и препарат для трансдермального введения никотина |
| ITMI20041628A1 (it) | 2004-08-06 | 2004-11-06 | Bouty S P A | Sistema terapeutico a rilascio controllato per uso topico transdermico |
| DE102005010255A1 (de) † | 2005-03-07 | 2006-09-14 | Lts Lohmann Therapie-Systeme Ag | Faserfreies transdermales therapeutisches System und Verfahren zu seiner Herstellung |
| JP5000932B2 (ja) * | 2005-06-21 | 2012-08-15 | 日東電工株式会社 | ニコチン含有経皮吸収製剤 |
| IL177071A0 (en) * | 2005-08-01 | 2006-12-10 | Nitto Denko Corp | Method of preparing a nicotine transdermal preparation |
| EP1774964B1 (en) * | 2005-10-13 | 2014-08-06 | Nitto Denko Corporation | Nicotine transdermal preparation and production method thereof |
| JP2009519246A (ja) * | 2005-12-08 | 2009-05-14 | フェルティン ファルマ | 経皮タバコアルカロイドパッチ |
| WO2007065428A1 (en) * | 2005-12-08 | 2007-06-14 | Fertin Pharma | Low flexural strength transdermal tobacco alkaloid patch |
| DE102006026060B4 (de) * | 2006-01-12 | 2013-01-31 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System enthaltend als Wirkstoff Nikotin und Verfahren zur Herstellung solcher Systeme |
| DE102006054733A1 (de) * | 2006-11-21 | 2008-05-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit |
| WO2008145119A1 (en) * | 2007-05-31 | 2008-12-04 | Fertin Pharma A/S | Transdermal tobacco alkaloid reservoir patch |
| KR101883410B1 (ko) * | 2011-04-22 | 2018-07-30 | 아이큐어 주식회사 | 경피 흡수 제제 및 그 제조방법 |
| FR2987561B1 (fr) * | 2012-03-02 | 2014-04-11 | Pf Medicament | Dispositif transdermique comprenant des micro-particules poreuses |
| CA2981397C (en) * | 2015-04-08 | 2023-04-04 | Lts Lohmann Therapie-Systeme Ag | Electrically heatable plaster |
| EP3346998B1 (en) * | 2015-08-17 | 2025-04-16 | Sidmak Laboratories (India) PVT. Ltd. | Topical film delivery system |
| DE102018220589A1 (de) * | 2018-11-29 | 2020-06-04 | Lts Lohmann Therapie-Systeme Ag | Transdermales System mit Überpflaster und Ringsystem |
| DE102020112143B4 (de) | 2020-05-05 | 2022-03-17 | Lts Lohmann Therapie-Systeme Ag | Nicotin - Corona |
| CA3203975A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| CA3216359A1 (en) | 2021-04-07 | 2022-10-13 | Battelle Memorial Institute | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers |
| AU2024353375A1 (en) | 2023-09-29 | 2026-04-09 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4278018A (en) * | 1979-11-16 | 1981-07-14 | Ncr Canada Ltd. - Ncr Canada Ltee | Printing means |
| JPS61251619A (ja) | 1985-04-30 | 1986-11-08 | Nitto Electric Ind Co Ltd | ニコチン含有テ−プ製剤 |
| DE3629304A1 (de) | 1986-08-28 | 1988-03-24 | Lohmann Gmbh & Co Kg | Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung |
| US6139868A (en) * | 1986-08-28 | 2000-10-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system, its use and production process |
| DE3727232A1 (de) * | 1987-08-14 | 1989-02-23 | Lohmann Therapie Syst Lts | Verfahren zur herstellung einer darreichungs- und/oder dosierungsform fuer arzneimittelwirkstoffe |
| US4943435A (en) | 1987-10-05 | 1990-07-24 | Pharmetrix Corporation | Prolonged activity nicotine patch |
| US4915950A (en) * | 1988-02-12 | 1990-04-10 | Cygnus Research Corporation | Printed transdermal drug delivery device |
| US5364630A (en) | 1988-06-14 | 1994-11-15 | Alza Corporation | Subsaturated nicotine transdermal therapeutic system |
| DE3827561C1 (https=) | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
| DE3843238C1 (https=) * | 1988-12-22 | 1990-02-22 | Lohmann Therapie Syst Lts | |
| DE3908432A1 (de) | 1989-03-14 | 1990-09-27 | Lohmann Therapie Syst Lts | Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung |
| EP0484543B1 (en) | 1990-04-24 | 1995-12-13 | Teijin Limited | Plaster |
| CA2075517C (en) * | 1992-04-01 | 1997-03-11 | John Wick | Transdermal patch incorporating a polymer film incorporated with an active agent |
| CA2142871A1 (en) | 1992-08-25 | 1994-03-03 | Jesus Miranda | Printed transdermal drug delivery device |
| WO1995001766A1 (en) | 1993-07-09 | 1995-01-19 | Cygnus Therapeutic Systems | Method and device for providing nicotine replacement therapy transdermally/transbuccally |
| DE4332094C2 (de) * | 1993-09-22 | 1995-09-07 | Lohmann Therapie Syst Lts | Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung |
| JP3021661B2 (ja) * | 1994-03-07 | 2000-03-15 | セラテック・インコーポレーテッド | 薬剤含有接着複合体の経皮放出デバイス |
| DE4416927C1 (de) | 1994-05-13 | 1995-08-31 | Lohmann Therapie Syst Lts | Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung |
| KR0155193B1 (ko) * | 1994-10-04 | 1998-10-15 | 신재인 | 중하중 취급 및 미끄럼 방지용 전방향 바퀴 |
| FR2732223B1 (fr) * | 1995-03-30 | 1997-06-13 | Sanofi Sa | Composition pharmaceutique pour administration transdermique |
| DE19653605C2 (de) * | 1996-12-20 | 2002-11-28 | Roehm Gmbh | Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems |
| DE19653606A1 (de) * | 1996-12-20 | 1998-06-25 | Roehm Gmbh | Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher |
| DE19826592A1 (de) * | 1998-06-15 | 1999-12-16 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung eines aus einzelnen Schichten bestehenden Laminats |
| NZ525878A (en) | 1998-12-07 | 2004-12-24 | Elan Pharma Int Ltd | A method of treating nicotine dependance with mecamylamine |
| DE19918106A1 (de) * | 1999-04-22 | 2000-10-26 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern |
-
2001
- 2001-03-03 DE DE10110391A patent/DE10110391A1/de not_active Ceased
-
2002
- 2002-02-19 KR KR1020037011540A patent/KR100873257B1/ko not_active Expired - Fee Related
- 2002-02-19 US US10/469,163 patent/US8226974B2/en not_active Expired - Fee Related
- 2002-02-19 IL IL15769202A patent/IL157692A0/xx unknown
- 2002-02-19 AU AU2002308289A patent/AU2002308289B2/en not_active Ceased
- 2002-02-19 MX MXPA03007903A patent/MXPA03007903A/es active IP Right Grant
- 2002-02-19 WO PCT/EP2002/001728 patent/WO2002069940A2/de not_active Ceased
- 2002-02-19 PL PL363697A patent/PL205582B1/pl unknown
- 2002-02-19 NZ NZ527824A patent/NZ527824A/en not_active IP Right Cessation
- 2002-02-19 EP EP02748317A patent/EP1372619B1/de not_active Expired - Lifetime
- 2002-02-19 BR BR0207738-8A patent/BR0207738A/pt not_active Application Discontinuation
- 2002-02-19 CN CNB028059018A patent/CN1330305C/zh not_active Expired - Fee Related
- 2002-02-19 RU RU2003129636/15A patent/RU2302856C2/ru active
- 2002-02-19 CA CA2440012A patent/CA2440012C/en not_active Expired - Lifetime
- 2002-02-19 JP JP2002569118A patent/JP2004529890A/ja active Pending
- 2002-02-19 CZ CZ20032379A patent/CZ20032379A3/cs unknown
- 2002-02-19 HU HU0303311A patent/HUP0303311A3/hu unknown
- 2002-02-19 ES ES02748317T patent/ES2386886T3/es not_active Expired - Lifetime
- 2002-02-28 AR ARP020100725A patent/AR035688A1/es unknown
- 2002-03-01 TW TW091103842A patent/TWI264312B/zh not_active IP Right Cessation
-
2003
- 2003-08-11 ZA ZA200306194A patent/ZA200306194B/en unknown
- 2003-09-01 IL IL157692A patent/IL157692A/en not_active IP Right Cessation
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