TWI264312B - Highly flexible transdermal therapeutic system with nicotine as active ingredient - Google Patents

Highly flexible transdermal therapeutic system with nicotine as active ingredient

Info

Publication number
TWI264312B
TWI264312B TW091103842A TW91103842A TWI264312B TW I264312 B TWI264312 B TW I264312B TW 091103842 A TW091103842 A TW 091103842A TW 91103842 A TW91103842 A TW 91103842A TW I264312 B TWI264312 B TW I264312B
Authority
TW
Taiwan
Prior art keywords
nicotine
active ingredient
transdermal therapeutic
highly flexible
therapeutic system
Prior art date
Application number
TW091103842A
Other languages
English (en)
Chinese (zh)
Inventor
Stefan Bracht
Sabine Warnus
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Application granted granted Critical
Publication of TWI264312B publication Critical patent/TWI264312B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW091103842A 2001-03-03 2002-03-01 Highly flexible transdermal therapeutic system with nicotine as active ingredient TWI264312B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10110391A DE10110391A1 (de) 2001-03-03 2001-03-03 Hochflexibles Nikotin transdermales therapeutisches System mit Nikotin als Wirkstoff

Publications (1)

Publication Number Publication Date
TWI264312B true TWI264312B (en) 2006-10-21

Family

ID=7676278

Family Applications (1)

Application Number Title Priority Date Filing Date
TW091103842A TWI264312B (en) 2001-03-03 2002-03-01 Highly flexible transdermal therapeutic system with nicotine as active ingredient

Country Status (21)

Country Link
US (1) US8226974B2 (https=)
EP (1) EP1372619B1 (https=)
JP (1) JP2004529890A (https=)
KR (1) KR100873257B1 (https=)
CN (1) CN1330305C (https=)
AR (1) AR035688A1 (https=)
AU (1) AU2002308289B2 (https=)
BR (1) BR0207738A (https=)
CA (1) CA2440012C (https=)
CZ (1) CZ20032379A3 (https=)
DE (1) DE10110391A1 (https=)
ES (1) ES2386886T3 (https=)
HU (1) HUP0303311A3 (https=)
IL (2) IL157692A0 (https=)
MX (1) MXPA03007903A (https=)
NZ (1) NZ527824A (https=)
PL (1) PL205582B1 (https=)
RU (1) RU2302856C2 (https=)
TW (1) TWI264312B (https=)
WO (1) WO2002069940A2 (https=)
ZA (1) ZA200306194B (https=)

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DE20321052U1 (de) * 2002-05-28 2005-09-22 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Pflaster, enthaltend Fentanylum
BRPI0412752B8 (pt) * 2003-07-24 2021-05-25 Glaxosmithkline Llc composição de filme de dissolução oral
RU2263503C1 (ru) * 2004-04-23 2005-11-10 Каш Тенгиз Способ получения препарата и препарат для трансдермального введения никотина
ITMI20041628A1 (it) 2004-08-06 2004-11-06 Bouty S P A Sistema terapeutico a rilascio controllato per uso topico transdermico
DE102005010255A1 (de) † 2005-03-07 2006-09-14 Lts Lohmann Therapie-Systeme Ag Faserfreies transdermales therapeutisches System und Verfahren zu seiner Herstellung
JP5000932B2 (ja) * 2005-06-21 2012-08-15 日東電工株式会社 ニコチン含有経皮吸収製剤
IL177071A0 (en) * 2005-08-01 2006-12-10 Nitto Denko Corp Method of preparing a nicotine transdermal preparation
EP1774964B1 (en) * 2005-10-13 2014-08-06 Nitto Denko Corporation Nicotine transdermal preparation and production method thereof
JP2009519246A (ja) * 2005-12-08 2009-05-14 フェルティン ファルマ 経皮タバコアルカロイドパッチ
WO2007065428A1 (en) * 2005-12-08 2007-06-14 Fertin Pharma Low flexural strength transdermal tobacco alkaloid patch
DE102006026060B4 (de) * 2006-01-12 2013-01-31 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System enthaltend als Wirkstoff Nikotin und Verfahren zur Herstellung solcher Systeme
DE102006054733A1 (de) * 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit
WO2008145119A1 (en) * 2007-05-31 2008-12-04 Fertin Pharma A/S Transdermal tobacco alkaloid reservoir patch
KR101883410B1 (ko) * 2011-04-22 2018-07-30 아이큐어 주식회사 경피 흡수 제제 및 그 제조방법
FR2987561B1 (fr) * 2012-03-02 2014-04-11 Pf Medicament Dispositif transdermique comprenant des micro-particules poreuses
CA2981397C (en) * 2015-04-08 2023-04-04 Lts Lohmann Therapie-Systeme Ag Electrically heatable plaster
EP3346998B1 (en) * 2015-08-17 2025-04-16 Sidmak Laboratories (India) PVT. Ltd. Topical film delivery system
DE102018220589A1 (de) * 2018-11-29 2020-06-04 Lts Lohmann Therapie-Systeme Ag Transdermales System mit Überpflaster und Ringsystem
DE102020112143B4 (de) 2020-05-05 2022-03-17 Lts Lohmann Therapie-Systeme Ag Nicotin - Corona
CA3203975A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
CA3216359A1 (en) 2021-04-07 2022-10-13 Battelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
AU2024353375A1 (en) 2023-09-29 2026-04-09 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
WO2025122954A1 (en) 2023-12-08 2025-06-12 Battelle Memorial Institute Use of dna origami nanostructures for molecular information based data storage systems

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US4278018A (en) * 1979-11-16 1981-07-14 Ncr Canada Ltd. - Ncr Canada Ltee Printing means
JPS61251619A (ja) 1985-04-30 1986-11-08 Nitto Electric Ind Co Ltd ニコチン含有テ−プ製剤
DE3629304A1 (de) 1986-08-28 1988-03-24 Lohmann Gmbh & Co Kg Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung
US6139868A (en) * 1986-08-28 2000-10-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
DE3727232A1 (de) * 1987-08-14 1989-02-23 Lohmann Therapie Syst Lts Verfahren zur herstellung einer darreichungs- und/oder dosierungsform fuer arzneimittelwirkstoffe
US4943435A (en) 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
US4915950A (en) * 1988-02-12 1990-04-10 Cygnus Research Corporation Printed transdermal drug delivery device
US5364630A (en) 1988-06-14 1994-11-15 Alza Corporation Subsaturated nicotine transdermal therapeutic system
DE3827561C1 (https=) 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
DE3843238C1 (https=) * 1988-12-22 1990-02-22 Lohmann Therapie Syst Lts
DE3908432A1 (de) 1989-03-14 1990-09-27 Lohmann Therapie Syst Lts Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung
EP0484543B1 (en) 1990-04-24 1995-12-13 Teijin Limited Plaster
CA2075517C (en) * 1992-04-01 1997-03-11 John Wick Transdermal patch incorporating a polymer film incorporated with an active agent
CA2142871A1 (en) 1992-08-25 1994-03-03 Jesus Miranda Printed transdermal drug delivery device
WO1995001766A1 (en) 1993-07-09 1995-01-19 Cygnus Therapeutic Systems Method and device for providing nicotine replacement therapy transdermally/transbuccally
DE4332094C2 (de) * 1993-09-22 1995-09-07 Lohmann Therapie Syst Lts Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung
JP3021661B2 (ja) * 1994-03-07 2000-03-15 セラテック・インコーポレーテッド 薬剤含有接着複合体の経皮放出デバイス
DE4416927C1 (de) 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
KR0155193B1 (ko) * 1994-10-04 1998-10-15 신재인 중하중 취급 및 미끄럼 방지용 전방향 바퀴
FR2732223B1 (fr) * 1995-03-30 1997-06-13 Sanofi Sa Composition pharmaceutique pour administration transdermique
DE19653605C2 (de) * 1996-12-20 2002-11-28 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems
DE19653606A1 (de) * 1996-12-20 1998-06-25 Roehm Gmbh Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher
DE19826592A1 (de) * 1998-06-15 1999-12-16 Lohmann Therapie Syst Lts Verfahren zur Herstellung eines aus einzelnen Schichten bestehenden Laminats
NZ525878A (en) 1998-12-07 2004-12-24 Elan Pharma Int Ltd A method of treating nicotine dependance with mecamylamine
DE19918106A1 (de) * 1999-04-22 2000-10-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern

Also Published As

Publication number Publication date
WO2002069940A3 (de) 2003-01-09
BR0207738A (pt) 2004-03-09
NZ527824A (en) 2005-05-27
CZ20032379A3 (cs) 2004-02-18
WO2002069940A2 (de) 2002-09-12
CN1330305C (zh) 2007-08-08
RU2003129636A (ru) 2005-01-27
US8226974B2 (en) 2012-07-24
DE10110391A1 (de) 2002-09-26
RU2302856C2 (ru) 2007-07-20
KR20030082952A (ko) 2003-10-23
CA2440012A1 (en) 2002-09-12
ZA200306194B (en) 2004-02-17
IL157692A0 (en) 2004-03-28
EP1372619B1 (de) 2012-05-30
AU2002308289B2 (en) 2006-07-20
JP2004529890A (ja) 2004-09-30
HUP0303311A3 (en) 2010-04-28
KR100873257B1 (ko) 2008-12-11
ES2386886T3 (es) 2012-09-04
MXPA03007903A (es) 2003-12-04
CA2440012C (en) 2011-05-31
PL363697A1 (en) 2004-11-29
EP1372619A2 (de) 2004-01-02
HUP0303311A2 (hu) 2004-01-28
CN1494421A (zh) 2004-05-05
IL157692A (en) 2012-06-28
PL205582B1 (pl) 2010-05-31
AR035688A1 (es) 2004-06-23
US20040096490A1 (en) 2004-05-20

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees