HUP0303311A2 - Hatóanyagként nikotint tartalmazó nagy flexibilitású transzdermális terápiás rendszer - Google Patents

Hatóanyagként nikotint tartalmazó nagy flexibilitású transzdermális terápiás rendszer

Info

Publication number
HUP0303311A2
HUP0303311A2 HU0303311A HUP0303311A HUP0303311A2 HU P0303311 A2 HUP0303311 A2 HU P0303311A2 HU 0303311 A HU0303311 A HU 0303311A HU P0303311 A HUP0303311 A HU P0303311A HU P0303311 A2 HUP0303311 A2 HU P0303311A2
Authority
HU
Hungary
Prior art keywords
nicotine
therapeutic system
transdermal therapeutic
active substance
highly flexible
Prior art date
Application number
HU0303311A
Other languages
English (en)
Inventor
Stefan Bracht
Sabine Warnus
Original Assignee
Lts Lohmann Therapie-Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie-Systeme Ag filed Critical Lts Lohmann Therapie-Systeme Ag
Publication of HUP0303311A2 publication Critical patent/HUP0303311A2/hu
Publication of HUP0303311A3 publication Critical patent/HUP0303311A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgya nikotint tartalmazó transzdermális terápiásrendszer, amely nikotin vonatkozásában át nem eresztő hátsó rétegből(1), egy a hátsó réteghez közvetlenül csatlakozó, nikotintartalmúközbenső mátrixrétegből (2), egy további nikotintartalmúmátrixrétegből (3) és egy leválasztható védőrétegből (4) áll, ahol amátrixrétegek (met-)akrilát-kopolimerekből vannak felépítve. Atalálmány szerint a rétegek vastagsága összességben legfeljebb 250 mmés a nikotintartalom legalább 1,5 mg/m2 alkalmazási felület. Ó
HU0303311A 2001-03-03 2002-02-19 Highly flexible transdermal therapeutic system having nicotine as active substance HUP0303311A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10110391A DE10110391A1 (de) 2001-03-03 2001-03-03 Hochflexibles Nikotin transdermales therapeutisches System mit Nikotin als Wirkstoff
PCT/EP2002/001728 WO2002069940A2 (de) 2001-03-03 2002-02-19 Hochflexibles transdermales therapeutisches system mit nikotin als wirkstoff

Publications (2)

Publication Number Publication Date
HUP0303311A2 true HUP0303311A2 (hu) 2004-01-28
HUP0303311A3 HUP0303311A3 (en) 2010-04-28

Family

ID=7676278

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303311A HUP0303311A3 (en) 2001-03-03 2002-02-19 Highly flexible transdermal therapeutic system having nicotine as active substance

Country Status (21)

Country Link
US (1) US8226974B2 (hu)
EP (1) EP1372619B1 (hu)
JP (1) JP2004529890A (hu)
KR (1) KR100873257B1 (hu)
CN (1) CN1330305C (hu)
AR (1) AR035688A1 (hu)
AU (1) AU2002308289B2 (hu)
BR (1) BR0207738A (hu)
CA (1) CA2440012C (hu)
CZ (1) CZ20032379A3 (hu)
DE (1) DE10110391A1 (hu)
ES (1) ES2386886T3 (hu)
HU (1) HUP0303311A3 (hu)
IL (2) IL157692A0 (hu)
MX (1) MXPA03007903A (hu)
NZ (1) NZ527824A (hu)
PL (1) PL205582B1 (hu)
RU (1) RU2302856C2 (hu)
TW (1) TWI264312B (hu)
WO (1) WO2002069940A2 (hu)
ZA (1) ZA200306194B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1509210A1 (de) * 2002-05-28 2005-03-02 LABTEC GESELLSCHAFT FüR TECHNOLOGISCHE FORSCHUNG UND ENTWICKLUNG MBH Pflaster, enthaltend fentanylum
HUE037508T2 (hu) * 2003-07-24 2018-09-28 Glaxosmithkline Llc Szájban oldódó filmek
ITMI20041628A1 (it) 2004-08-06 2004-11-06 Bouty S P A Sistema terapeutico a rilascio controllato per uso topico transdermico
DE102005010255A1 (de) 2005-03-07 2006-09-14 Lts Lohmann Therapie-Systeme Ag Faserfreies transdermales therapeutisches System und Verfahren zu seiner Herstellung
JP5000932B2 (ja) * 2005-06-21 2012-08-15 日東電工株式会社 ニコチン含有経皮吸収製剤
IL177071A0 (en) * 2005-08-01 2006-12-10 Nitto Denko Corp Method of preparing a nicotine transdermal preparation
EP1774964B1 (en) * 2005-10-13 2014-08-06 Nitto Denko Corporation Nicotine transdermal preparation and production method thereof
US20090169606A1 (en) * 2005-12-08 2009-07-02 Fertin Pharma Low Flexural Strength Transdermal Tobacco Alkaloid Patch
US20090246264A1 (en) * 2005-12-08 2009-10-01 Fertin Pharma Transdermal Tobacco Alkaloid Patch
DE102006026060B4 (de) * 2006-01-12 2013-01-31 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System enthaltend als Wirkstoff Nikotin und Verfahren zur Herstellung solcher Systeme
DE102006054733A1 (de) * 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit
EP2167055A1 (en) * 2007-05-31 2010-03-31 Fertin Pharma A/S Transdermal tobacco alkaloid reservoir patch
KR101883410B1 (ko) * 2011-04-22 2018-07-30 아이큐어 주식회사 경피 흡수 제제 및 그 제조방법
FR2987561B1 (fr) * 2012-03-02 2014-04-11 Pf Medicament Dispositif transdermique comprenant des micro-particules poreuses
US11364153B2 (en) * 2015-04-08 2022-06-21 Lts Lohmann Therapie-System Ag Electrically-heatable plaster
CA3033570C (en) * 2015-08-17 2022-12-06 Sidmak Laboratories (India) Pvt. Ltd. Topical film delivery system
DE102018220589A1 (de) * 2018-11-29 2020-06-04 Lts Lohmann Therapie-Systeme Ag Transdermales System mit Überpflaster und Ringsystem
DE102020112143B4 (de) 2020-05-05 2022-03-17 Lts Lohmann Therapie-Systeme Ag Nicotin - Corona

Family Cites Families (23)

* Cited by examiner, † Cited by third party
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US4278018A (en) * 1979-11-16 1981-07-14 Ncr Canada Ltd. - Ncr Canada Ltee Printing means
JPS61251619A (ja) * 1985-04-30 1986-11-08 Nitto Electric Ind Co Ltd ニコチン含有テ−プ製剤
DE3629304A1 (de) 1986-08-28 1988-03-24 Lohmann Gmbh & Co Kg Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung
US6139868A (en) * 1986-08-28 2000-10-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
DE3727232A1 (de) 1987-08-14 1989-02-23 Lohmann Therapie Syst Lts Verfahren zur herstellung einer darreichungs- und/oder dosierungsform fuer arzneimittelwirkstoffe
US4943435A (en) * 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
US4915950A (en) * 1988-02-12 1990-04-10 Cygnus Research Corporation Printed transdermal drug delivery device
US5364630A (en) 1988-06-14 1994-11-15 Alza Corporation Subsaturated nicotine transdermal therapeutic system
DE3827561C1 (hu) 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
DE3908432A1 (de) 1989-03-14 1990-09-27 Lohmann Therapie Syst Lts Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung
KR950005865B1 (ko) 1990-04-23 1995-06-02 데이진 가부시끼가이샤 첩부제
CA2075517C (en) 1992-04-01 1997-03-11 John Wick Transdermal patch incorporating a polymer film incorporated with an active agent
CA2142871A1 (en) 1992-08-25 1994-03-03 Jesus Miranda Printed transdermal drug delivery device
WO1995001766A1 (en) * 1993-07-09 1995-01-19 Cygnus Therapeutic Systems Method and device for providing nicotine replacement therapy transdermally/transbuccally
DE4332094C2 (de) * 1993-09-22 1995-09-07 Lohmann Therapie Syst Lts Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung
AU676430B2 (en) * 1994-03-07 1997-03-06 Theratech, Inc. Drug-containing adhesive composite transdermal delivery device
DE4416927C1 (de) 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
KR0155193B1 (ko) * 1994-10-04 1998-10-15 신재인 중하중 취급 및 미끄럼 방지용 전방향 바퀴
DE19653605C2 (de) * 1996-12-20 2002-11-28 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems
DE19653606A1 (de) * 1996-12-20 1998-06-25 Roehm Gmbh Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher
DE19826592A1 (de) * 1998-06-15 1999-12-16 Lohmann Therapie Syst Lts Verfahren zur Herstellung eines aus einzelnen Schichten bestehenden Laminats
DE69916492T3 (de) 1998-12-07 2008-08-14 J. Dev Ltd., Athlone Pflaster zur transdermalen applikation von flüchtigen, flüssigen wirkstoffen
DE19918106A1 (de) * 1999-04-22 2000-10-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern

Also Published As

Publication number Publication date
TWI264312B (en) 2006-10-21
CA2440012A1 (en) 2002-09-12
KR100873257B1 (ko) 2008-12-11
CZ20032379A3 (cs) 2004-02-18
WO2002069940A3 (de) 2003-01-09
US20040096490A1 (en) 2004-05-20
CN1494421A (zh) 2004-05-05
NZ527824A (en) 2005-05-27
JP2004529890A (ja) 2004-09-30
CN1330305C (zh) 2007-08-08
RU2302856C2 (ru) 2007-07-20
BR0207738A (pt) 2004-03-09
KR20030082952A (ko) 2003-10-23
MXPA03007903A (es) 2003-12-04
AU2002308289B2 (en) 2006-07-20
EP1372619B1 (de) 2012-05-30
DE10110391A1 (de) 2002-09-26
US8226974B2 (en) 2012-07-24
AR035688A1 (es) 2004-06-23
RU2003129636A (ru) 2005-01-27
WO2002069940A2 (de) 2002-09-12
IL157692A (en) 2012-06-28
EP1372619A2 (de) 2004-01-02
PL205582B1 (pl) 2010-05-31
IL157692A0 (en) 2004-03-28
PL363697A1 (en) 2004-11-29
HUP0303311A3 (en) 2010-04-28
CA2440012C (en) 2011-05-31
ES2386886T3 (es) 2012-09-04
ZA200306194B (en) 2004-02-17

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees