HUP0001748A2 - Transzdermális eszköz tesztoszteron felszabadítására - Google Patents

Transzdermális eszköz tesztoszteron felszabadítására

Info

Publication number
HUP0001748A2
HUP0001748A2 HU0001748A HUP0001748A HUP0001748A2 HU P0001748 A2 HUP0001748 A2 HU P0001748A2 HU 0001748 A HU0001748 A HU 0001748A HU P0001748 A HUP0001748 A HU P0001748A HU P0001748 A2 HUP0001748 A2 HU P0001748A2
Authority
HU
Hungary
Prior art keywords
testosterone
delivery
subject
transdermal device
release
Prior art date
Application number
HU0001748A
Other languages
English (en)
Inventor
John C. Hedenstrom
Michael L. Husberg
Shari L. Myszka
Matthew T. Scholz
Original Assignee
Minnesota Mining And Manufacturing Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining And Manufacturing Co. filed Critical Minnesota Mining And Manufacturing Co.
Publication of HUP0001748A2 publication Critical patent/HUP0001748A2/hu
Publication of HUP0001748A3 publication Critical patent/HUP0001748A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Abstract

A találmány tárgya eszköz tesztoszteron transzdermálisfelszabadítására. Az eszköz hátoldalának egyik felületén tapadórétegethordoz, amely (a) nyomásérzékeny, bőrre tapadó anyagból; (b)terápiásan hatásos mennyiségű tesztoszteronból, és (c) terpénttartalmazó, a felszabadulást elősegítő segédanyagból áll. A találmánytárgyát képezi továbbá egy eljárás tesztoszteronhiánnyal kapcsolatoskóros állapot kezelésére alkalmas gyógyszerkészítmény előállítására. Ó
HU0001748A 1997-02-28 1998-02-27 Transdermal device for the delivery of testosterone HUP0001748A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3927497P 1997-02-28 1997-02-28

Publications (2)

Publication Number Publication Date
HUP0001748A2 true HUP0001748A2 (hu) 2000-12-28
HUP0001748A3 HUP0001748A3 (en) 2001-03-28

Family

ID=21904596

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001748A HUP0001748A3 (en) 1997-02-28 1998-02-27 Transdermal device for the delivery of testosterone

Country Status (16)

Country Link
US (1) US6132760A (hu)
EP (1) EP0979072B1 (hu)
JP (1) JP2001517216A (hu)
KR (1) KR20000075804A (hu)
AT (1) ATE293960T1 (hu)
AU (1) AU735944B2 (hu)
BR (1) BR9807786A (hu)
CA (1) CA2281876A1 (hu)
DE (1) DE69829961T2 (hu)
HU (1) HUP0001748A3 (hu)
NO (1) NO994042L (hu)
NZ (1) NZ337135A (hu)
PL (1) PL335410A1 (hu)
SK (1) SK116199A3 (hu)
TR (1) TR199902104T2 (hu)
WO (1) WO1998037871A1 (hu)

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FR2793689B1 (fr) * 1999-05-19 2001-08-24 Pf Medicament Dispositif transdermique pour l'administration de testosterone ou d'un de ses derives
US6673363B2 (en) 1999-12-16 2004-01-06 Dermatrends, Inc. Transdermal and topical administration of local anesthetic agents using basic enhancers
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US6586000B2 (en) * 1999-12-16 2003-07-01 Dermatrends, Inc. Hydroxide-releasing agents as skin permeation enhancers
US6582724B2 (en) * 1999-12-16 2003-06-24 Dermatrends, Inc. Dual enhancer composition for topical and transdermal drug delivery
US6562369B2 (en) 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of androgenic drugs hydroxide-releasing agents as permeation enhancers
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
WO2002024157A2 (en) * 2000-09-19 2002-03-28 National Starch And Chemical Investment Holding Corporation Acryl adhesive useful in transdermal drug delivery systems
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
EP1390383B1 (en) * 2001-05-11 2012-02-29 Isis Pharmaceuticals, Inc. Antisense permeation enhancers
KR100517637B1 (ko) * 2001-12-21 2005-09-28 씨제이 주식회사 섬수 정제 엑스 및 인삼 정제 엑스를 함께 함유하면서다른 정유 생약 성분은 함유하지 않는 조루증의 예방 및치료용 조성물
US20040062794A1 (en) * 2002-09-30 2004-04-01 Lee Shulman 17Beta- estradiol/levonorgestrel transdermal patch for hormone replacement therapy
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
ME00276B (me) 2003-04-30 2011-05-10 Purdue Pharma Lp Transdermalni dozni oblik otporan na promjene koje sadrže komponentu aktivnog sredstva i komponentu suprotnog sredstva na mjestu koji je ispod sloja aktivnog sredstva
US20040259852A1 (en) * 2003-06-18 2004-12-23 White Hillary D. Trandsdermal compositions and methods for treatment of fibromyalgia and chronic fatigue syndrome
US8883769B2 (en) * 2003-06-18 2014-11-11 White Mountain Pharma, Inc. Methods for the treatment of fibromyalgia and chronic fatigue syndrome
JP2007524616A (ja) * 2003-06-20 2007-08-30 ヴァイラル・ジェノミックス・インコーポレーテッド Ｈｉｖを処置するための組成物および方法
AU2004291043A1 (en) * 2003-11-18 2005-06-02 3M Innovative Properties Company Olanzapine containing transdermal drug delivery compositions
JP4567998B2 (ja) * 2004-03-22 2010-10-27 コスメディ製薬株式会社 親水性粘着剤を用いた親水性皮膚外用粘着剤組成物および親水性貼付剤
AU2006299833B2 (en) 2005-10-12 2012-04-12 Besins Healthcare Luxembourg Sarl Improved testosterone gel and method of use
US20080132475A1 (en) * 2006-12-05 2008-06-05 Charles Gerald Connor Treatment for dry eye
US20100016264A1 (en) * 2007-12-05 2010-01-21 Connor Charles G Treatment for dry eye using testosterone and progestagen
FR2924942B1 (fr) * 2007-12-14 2012-06-15 Pf Medicament Compositions pharmaceutiques transcutanees contenant une hormone steroidienne
US8445037B2 (en) * 2008-10-28 2013-05-21 A. M. Todd Company Volatile distillate by-product of mint oil that promotes absorption and/or bioavailability of compounds of bio-medical and nutritional interest
EP2640398A4 (en) 2010-11-18 2014-05-14 White Mountain Pharma Inc METHODS FOR TREATING CHRONIC OR REFRACTORY PAIN AND / OR INCREASING PAIN THRESHOLD IN A SUBJECT, AND ASSOCIATED PHARMACEUTICAL COMPOSITIONS
US20170007464A1 (en) * 2013-12-20 2017-01-12 3M Innovative Properties Company Antimicrobial pressure-sensitive adhesive system
UY35923A (es) * 2013-12-30 2015-07-31 Rhodia Operations ?composiciones pesticidas agrícolas?.
US11813354B1 (en) 2019-01-11 2023-11-14 Shear Kershman Laboratories, Inc Trans-mucosal delivery system for testosterone

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AU622162B2 (en) * 1988-04-22 1992-04-02 Ciba-Geigy Ag Transdermal monolith systems
WO1991005529A1 (en) * 1989-10-13 1991-05-02 Watson Laboratories, Inc. Drug delivery systems and matrix therefor
US5240932A (en) * 1990-03-30 1993-08-31 Yasunori Morimoto Percutaneously absorbable compositions of morphine or analogous analgesics of morphine
US5152997A (en) * 1990-12-11 1992-10-06 Theratech, Inc. Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels
US5164190A (en) * 1990-12-11 1992-11-17 Theratech, Inc. Subsaturated transdermal drug delivery device exhibiting enhanced drug flux
EP0491076A1 (en) * 1990-12-19 1992-06-24 Theratech, Inc. Penetration enhancement with multi-component system of N-aliphatic pyrrolidones with lower alcohols
US5211952A (en) * 1991-04-12 1993-05-18 University Of Southern California Contraceptive methods and formulations for use therein
US5340586A (en) * 1991-04-12 1994-08-23 University Of Southern California Methods and formulations for use in treating oophorectomized women
DE4210165A1 (de) * 1991-07-30 1993-02-04 Schering Ag Transdermale therapeutische systeme
US5676968A (en) * 1991-10-31 1997-10-14 Schering Aktiengesellschaft Transdermal therapeutic systems with crystallization inhibitors
US5230897A (en) * 1991-10-31 1993-07-27 G. D. Searle & Co. Transdermal pentamidine
CA2075517C (en) * 1992-04-01 1997-03-11 John Wick Transdermal patch incorporating a polymer film incorporated with an active agent
JP3548195B2 (ja) * 1993-05-27 2004-07-28 リンテック株式会社 経皮吸収型製剤
US5460820B1 (en) * 1993-08-03 1999-08-03 Theratech Inc Method for providing testosterone and optionally estrogen replacement therapy to women
JP3908795B2 (ja) * 1994-11-29 2007-04-25 久光製薬株式会社 ケトチフェン含有経皮投与製剤

Also Published As

Publication number Publication date
KR20000075804A (ko) 2000-12-26
EP0979072A1 (en) 2000-02-16
NZ337135A (en) 2001-07-27
AU735944B2 (en) 2001-07-19
JP2001517216A (ja) 2001-10-02
DE69829961D1 (de) 2005-06-02
ATE293960T1 (de) 2005-05-15
NO994042L (no) 1999-10-26
CA2281876A1 (en) 1998-09-03
TR199902104T2 (xx) 2000-04-21
SK116199A3 (en) 2000-01-18
BR9807786A (pt) 2000-02-22
EP0979072B1 (en) 2005-04-27
US6132760A (en) 2000-10-17
WO1998037871A1 (en) 1998-09-03
DE69829961T2 (de) 2006-02-23
NO994042D0 (no) 1999-08-20
HUP0001748A3 (en) 2001-03-28
PL335410A1 (en) 2000-04-25
AU6539098A (en) 1998-09-18

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