JP2004529884A5 - - Google Patents
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- Publication number
- JP2004529884A5 JP2004529884A5 JP2002567231A JP2002567231A JP2004529884A5 JP 2004529884 A5 JP2004529884 A5 JP 2004529884A5 JP 2002567231 A JP2002567231 A JP 2002567231A JP 2002567231 A JP2002567231 A JP 2002567231A JP 2004529884 A5 JP2004529884 A5 JP 2004529884A5
- Authority
- JP
- Japan
- Prior art keywords
- radiopharmaceutical composition
- formula
- substituted
- radiopharmaceutical
- biomolecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 13
- 229940121896 radiopharmaceutical Drugs 0.000 claims 13
- 239000012217 radiopharmaceutical Substances 0.000 claims 13
- 230000002799 radiopharmaceutical effect Effects 0.000 claims 13
- 239000002738 chelating agent Substances 0.000 claims 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 3
- 239000002184 metal Substances 0.000 claims 3
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 2
- 125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000000084 colloidal system Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 229940127043 diagnostic radiopharmaceutical Drugs 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 229940127044 therapeutic radiopharmaceutical Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27138901P | 2001-02-26 | 2001-02-26 | |
| PCT/US2002/005155 WO2002067859A2 (en) | 2001-02-26 | 2002-02-22 | Ascorbic acid analogs for metalloradiopharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004529884A JP2004529884A (ja) | 2004-09-30 |
| JP2004529884A5 true JP2004529884A5 (https=) | 2005-12-22 |
Family
ID=23035343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567231A Pending JP2004529884A (ja) | 2001-02-26 | 2002-02-22 | 金属放射性医薬のためのアスコルビン酸類似体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6713042B2 (https=) |
| EP (1) | EP1365813A4 (https=) |
| JP (1) | JP2004529884A (https=) |
| CN (1) | CN1503680A (https=) |
| AU (1) | AU2002253999A1 (https=) |
| BR (1) | BR0207315A (https=) |
| CA (1) | CA2438204A1 (https=) |
| CZ (1) | CZ20032597A3 (https=) |
| HU (1) | HUP0304083A2 (https=) |
| IL (1) | IL157359A0 (https=) |
| MX (1) | MXPA03007595A (https=) |
| WO (1) | WO2002067859A2 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10305463A1 (de) * | 2003-02-04 | 2004-08-12 | Schering Ag | Enantiomerenreines (4S,8S)- und (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triza-3N,6N,9N-tricarboxymethyl-1,11-undecandisäure und deren Abkömmlinge, Verfahren zu deren Herstellung und Verwendung zur Herstellung pharmazeutischer Mittel |
| US20050089470A1 (en) * | 2003-10-24 | 2005-04-28 | Johnson Bruce F. | Labeled peptides for lectin-like oxidized low-density lipoprotein receptor (LOX-1) |
| US20050089471A1 (en) * | 2003-10-24 | 2005-04-28 | Johnson Bruce F. | Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1) |
| US20060210479A1 (en) * | 2004-08-10 | 2006-09-21 | Dow Global Technologies Inc. | Targeting chelants and chelates |
| GB0427392D0 (en) * | 2004-12-15 | 2005-01-19 | Amersham Plc | Stabilised 99mTc compositions |
| TW200803903A (en) * | 2006-04-28 | 2008-01-16 | Nihon Mediphysics Co Ltd | Novel compound having affinity to amyloid |
| US8303935B2 (en) * | 2006-05-19 | 2012-11-06 | Nihon Medi-Physics Co., Ltd. | Alkoxy substituted imidazo[1,2-a]pyridines having affinity for amyloid |
| WO2007148755A1 (ja) * | 2006-06-21 | 2007-12-27 | Nihon Medi-Physics Co., Ltd. | 新規アミロイド親和性化合物 |
| CA2654369C (en) * | 2006-06-21 | 2014-10-14 | Ge Healthcare Limited | Radiopharmaceutical products |
| US20100056826A1 (en) * | 2006-11-09 | 2010-03-04 | Nihon Medi-Physicis Co., Ltd. | Radioactive diagnostic imaging agent |
| US20090252680A1 (en) * | 2006-11-17 | 2009-10-08 | Nihon- Medi-Physics Co., Ltd | Novel compound with affinity for amyloid |
| CA2670436A1 (en) * | 2006-11-30 | 2008-06-05 | Nihon Medi-Physics Co., Ltd. | Novel compound having affinity for amyloid |
| PT2106808T (pt) * | 2006-12-21 | 2018-03-26 | Nihon Mediphysics Co Ltd | Agente de imagiologia de diagnóstico radioativo compreendendo ácido 1-amino-3-[18f]fluoro-ciclobutanocarboxílico |
| JP5258583B2 (ja) | 2007-02-13 | 2013-08-07 | 日本メジフィジックス株式会社 | 放射性画像診断剤の製造方法 |
| GB0718386D0 (en) * | 2007-09-21 | 2007-10-31 | Ge Healthcare As | Improved radiopharmaceutical formulation |
| KR20100091965A (ko) * | 2007-10-24 | 2010-08-19 | 니혼 메디피직스 가부시키가이샤 | 신규 아밀로이드 친화성 화합물 |
| EP2216052A4 (en) * | 2007-10-30 | 2012-11-21 | Nihon Mediphysics Co Ltd | USE OF A NEW COMPOUND WITH AFFINITY FOR AMYLOID AND METHOD FOR THE PRODUCTION THEREOF |
| WO2009057576A1 (ja) * | 2007-10-30 | 2009-05-07 | Nihon Medi-Physics Co., Ltd. | 新規アミロイド親和性化合物の使用及び製造方法 |
| CA2706111C (en) * | 2007-12-04 | 2013-06-18 | Bracco Imaging S.P.A. | Homogenization of a radiopharmaceutical using sonification and/or rotor-stator technology to produce a homogenous suspension, emulsion, mixture or solid suspension of immiscible ingredients |
| RU2011112946A (ru) * | 2008-09-05 | 2012-10-10 | Молекьюлар Инсайт Фармасьютикалз, Инк. (Us) | Фармацевтическая композиция радиойодированного бензамидного производного и способы ее получения |
| FR2942227B1 (fr) * | 2009-02-13 | 2011-04-15 | Guerbet Sa | Utilisation de tampons pour la complexation de radionucleides |
| KR20160030589A (ko) | 2009-04-15 | 2016-03-18 | 랜티우스 메디컬 이메징, 인크. | 아스코르브산을 사용한 방사성 약제 조성물의 안정화 |
| US9321095B2 (en) | 2010-06-30 | 2016-04-26 | General Electric Company | Apparatuses and methods for cutting porous substrates |
| WO2013093099A1 (en) * | 2011-12-22 | 2013-06-27 | Piramal Imaging Sa | Stabilization of peptidic radiopharmaceuticals using uric acid or derivatives thereof |
| WO2013176522A1 (ko) * | 2012-05-24 | 2013-11-28 | 서강대학교산학협력단 | 카트리지를 이용한 방사성의약품 제조방법 |
| US20140147381A1 (en) * | 2012-11-29 | 2014-05-29 | Gregory David Espenan | 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment |
| CA2901231C (en) * | 2013-02-15 | 2020-06-23 | Thomas Jefferson University | Kit comprising lyophilized compositions for tumor imaging |
| JP6500105B2 (ja) * | 2014-11-27 | 2019-04-10 | セルトリオン・インコーポレイテッド | ペプチドが結合された安定したアスコルビン酸誘導体、その製造方法、及びそれを含む化粧料組成物 |
| TWI604853B (zh) * | 2016-05-03 | 2017-11-11 | 行政院原子能委員會核能研究所 | 放射免疫複合體、診療劑及套組 |
| CN107167540B (zh) * | 2017-07-08 | 2019-07-30 | 万舒（北京）医药科技有限公司 | 测定人尿液生物样品中的DTPA-Zn的方法 |
| KR102207372B1 (ko) * | 2020-03-31 | 2021-01-27 | 재단법인 아산사회복지재단 | 방사성 의약품의 안정화제 및 이를 포함하는 방사성 의약 조성물 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL42204A (en) * | 1972-05-08 | 1976-09-30 | Solco Basel Ag | Process and apparatus for the manufacture of injectable radionuclide preparations |
| US4504462A (en) * | 1982-06-10 | 1985-03-12 | Mallinckrodt, Inc. | Process for making a lyophilized product for use in skeletal imaging |
| US4707353A (en) * | 1982-12-08 | 1987-11-17 | Mallinckrodt, Inc. | Radiographic imaging agents |
| US5985240A (en) * | 1989-08-09 | 1999-11-16 | Rhomed Incorporated | Peptide radiopharmaceutical applications |
| DE69007229T2 (de) * | 1989-10-09 | 1994-06-16 | Unilever Nv | Verfahren zur Herstellung von essbaren Aufstrichen und Anlage dafür. |
| DK0600992T3 (da) * | 1991-08-29 | 2000-10-09 | Mallinckrodt Medical Inc | Anvendelse af gentissyre eller gentisylalkohol til stabilisering af radiomærkede peptider og proteiner |
| GB9417873D0 (en) * | 1994-09-06 | 1994-10-26 | Sandoz Ltd | Organic compounds |
| US6066309A (en) | 1996-02-02 | 2000-05-23 | Rhomed Incorporated | Post-labeling stabilization of radiolabeled proteins and peptides |
| AU2526497A (en) * | 1996-02-02 | 1997-08-22 | Rhomed Incorporated | Post-labeling stabilization of radiolabeled proteins and peptides |
| US5961955A (en) * | 1997-06-03 | 1999-10-05 | Coulter Pharmaceutical, Inc. | Radioprotectant for peptides labeled with radioisotope |
| CA2413538A1 (en) * | 2000-07-06 | 2002-01-17 | Bristol-Myers Squibb Pharma Company | Stable radiopharmaceutical compositions and methods for preparation thereof |
-
2002
- 2002-02-22 CZ CZ20032597A patent/CZ20032597A3/cs unknown
- 2002-02-22 HU HU0304083A patent/HUP0304083A2/hu unknown
- 2002-02-22 CN CNA028087186A patent/CN1503680A/zh active Pending
- 2002-02-22 CA CA002438204A patent/CA2438204A1/en not_active Abandoned
- 2002-02-22 WO PCT/US2002/005155 patent/WO2002067859A2/en not_active Ceased
- 2002-02-22 MX MXPA03007595A patent/MXPA03007595A/es active IP Right Grant
- 2002-02-22 IL IL15735902A patent/IL157359A0/xx unknown
- 2002-02-22 EP EP02723206A patent/EP1365813A4/en not_active Withdrawn
- 2002-02-22 AU AU2002253999A patent/AU2002253999A1/en not_active Abandoned
- 2002-02-22 US US10/081,258 patent/US6713042B2/en not_active Expired - Fee Related
- 2002-02-22 BR BR0207315-3A patent/BR0207315A/pt not_active IP Right Cessation
- 2002-02-22 JP JP2002567231A patent/JP2004529884A/ja active Pending
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