JP2004525190A5 - - Google Patents
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- Publication number
- JP2004525190A5 JP2004525190A5 JP2002586832A JP2002586832A JP2004525190A5 JP 2004525190 A5 JP2004525190 A5 JP 2004525190A5 JP 2002586832 A JP2002586832 A JP 2002586832A JP 2002586832 A JP2002586832 A JP 2002586832A JP 2004525190 A5 JP2004525190 A5 JP 2004525190A5
- Authority
- JP
- Japan
- Prior art keywords
- dental composition
- composition according
- liposome
- potassium
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 20
- 239000002502 liposome Substances 0.000 claims 7
- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims 4
- 210000005036 nerve Anatomy 0.000 claims 4
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 4
- 210000005239 tubule Anatomy 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims 2
- 229940090898 Desensitizer Drugs 0.000 claims 2
- 239000005770 Eugenol Substances 0.000 claims 2
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims 2
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims 2
- 125000000129 anionic group Chemical group 0.000 claims 2
- 229960002504 capsaicin Drugs 0.000 claims 2
- 235000017663 capsaicin Nutrition 0.000 claims 2
- 239000003975 dentin desensitizing agent Substances 0.000 claims 2
- 229960002217 eugenol Drugs 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 claims 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 claims 2
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 201000002170 dentin sensitivity Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000009610 hypersensitivity Effects 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 235000010755 mineral Nutrition 0.000 claims 1
- 239000011736 potassium bicarbonate Substances 0.000 claims 1
- 235000015497 potassium bicarbonate Nutrition 0.000 claims 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 claims 1
- 239000001103 potassium chloride Substances 0.000 claims 1
- 235000011164 potassium chloride Nutrition 0.000 claims 1
- 239000001508 potassium citrate Substances 0.000 claims 1
- 229960002635 potassium citrate Drugs 0.000 claims 1
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 claims 1
- 235000011082 potassium citrates Nutrition 0.000 claims 1
- 239000011698 potassium fluoride Substances 0.000 claims 1
- 235000003270 potassium fluoride Nutrition 0.000 claims 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 claims 1
- 239000004323 potassium nitrate Substances 0.000 claims 1
- 235000010333 potassium nitrate Nutrition 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
- 239000011775 sodium fluoride Substances 0.000 claims 1
- 235000013024 sodium fluoride Nutrition 0.000 claims 1
- 229960000414 sodium fluoride Drugs 0.000 claims 1
- ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 claims 1
- 229960002799 stannous fluoride Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/848,138 US6416745B1 (en) | 2001-05-03 | 2001-05-03 | Dental composition for treating hypersensitive teeth |
| PCT/US2002/013978 WO2002089690A2 (en) | 2001-05-03 | 2002-05-03 | Dental composition for treating hypersensitive teeth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004525190A JP2004525190A (ja) | 2004-08-19 |
| JP2004525190A5 true JP2004525190A5 (cg-RX-API-DMAC7.html) | 2005-12-22 |
| JP3946644B2 JP3946644B2 (ja) | 2007-07-18 |
Family
ID=25302447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002586832A Expired - Fee Related JP3946644B2 (ja) | 2001-05-03 | 2002-05-03 | 過敏性の歯を治療するための歯の組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6416745B1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1390004B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP3946644B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE435053T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002308581A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0209368A (cg-RX-API-DMAC7.html) |
| DE (1) | DE60232790D1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002089690A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6416745B1 (en) * | 2001-05-03 | 2002-07-09 | Block Drug Company, Inc. | Dental composition for treating hypersensitive teeth |
| EP1432403B1 (en) * | 2001-10-03 | 2010-07-28 | Celator Pharmaceuticals, Inc. | Liposome loading with metal ions |
| US6814794B2 (en) * | 2002-11-06 | 2004-11-09 | Ultradent Products, Inc. | Temporary dental cements having reduced tooth sensitivity |
| US20040146464A1 (en) * | 2003-01-23 | 2004-07-29 | Bernstein Joel E. | Compositions and method for daily tooth and gum care |
| US20040146831A1 (en) * | 2003-01-23 | 2004-07-29 | Kerrhawe Sa | Unit dose delivery system for dental sensitivity product |
| US20040185027A1 (en) * | 2003-02-21 | 2004-09-23 | Reierson Robert Lee | Anti-sensitivity, anti-caries, anti-staining, anti-plaque, ultra-mild oral hygiene agent |
| AU2005270010A1 (en) * | 2004-07-02 | 2006-02-09 | Discus Dental, Llc. | Dental compositions with sensitivity relief |
| WO2006071659A1 (en) * | 2004-12-29 | 2006-07-06 | Trustees Of Boston University | Delivery of h2 antagonists |
| US20070258916A1 (en) * | 2006-04-14 | 2007-11-08 | Oregon Health & Science University | Oral compositions for treating tooth hypersensitivity |
| RU2362543C1 (ru) * | 2007-12-12 | 2009-07-27 | Закрытое Акционерное Общество "Лиэп" | Дентальная липосомальная композиция и зубная паста, включающая указанную липосомальную композицию |
| AU2009212333C1 (en) * | 2008-02-08 | 2012-07-19 | Colgate-Palmolive Company | Compositions and devices |
| US20100047742A1 (en) * | 2008-08-25 | 2010-02-25 | Pitcock Jr William Henry | Tubule-blocking silica materials for dentifrices |
| US8905760B2 (en) * | 2008-11-04 | 2014-12-09 | Duane C. Keller | Methods and systems for progressively treating and controlling oral periopathogens causing systemic inflammations |
| US8956161B2 (en) | 2008-11-04 | 2015-02-17 | Duane C Keller | Article and method for controlling oral-originated systemic disease |
| RU2496481C2 (ru) | 2008-11-10 | 2013-10-27 | Колгейт-Палмолив Компани | Капсулы, стабильные при хранении |
| AR076178A1 (es) * | 2009-04-01 | 2011-05-26 | Colgate Palmolive Co | Composiciones dentifricas de accion doble para prevenir la hipersensibilidad y promover la remineralizacion |
| US20110206749A1 (en) * | 2010-02-19 | 2011-08-25 | J.M. Huber Corporation | Silica materials for reducing oral malador |
| US8658139B1 (en) | 2010-02-27 | 2014-02-25 | Squigle, Inc. | Prevention and treatment of oral diseases |
| US20110236444A1 (en) * | 2010-03-25 | 2011-09-29 | Darsillo Michael S | Antimicrobial Silica Composites |
| US20120003162A1 (en) | 2010-06-30 | 2012-01-05 | Mcneil-Ppc, Inc. | Methods of Preparing Non-Alcohol Bioactive Esential Oil Mouth Rinses |
| US9084902B2 (en) | 2010-06-30 | 2015-07-21 | Mcneil-Ppc, Inc. | Non-alchohol bioactive essential oil mouth rinses |
| US8591229B2 (en) | 2010-12-16 | 2013-11-26 | Duane C. Keller | Devices and methods for creating a positive pressure environment for treatment of oral biofilms associated with periodontal disease |
| US10485867B2 (en) * | 2013-09-19 | 2019-11-26 | Allovate, Llc | Toothpaste for delivery of allergens to oral mucosa |
| AU2015346374A1 (en) | 2014-11-11 | 2017-04-27 | Johnson & Johnson Consumer Inc. | Amino acid derivatives and their uses |
| EP3217952B9 (en) | 2014-11-11 | 2019-09-04 | Johnson & Johnson Consumer Inc. | Amino acid derivatives and their uses |
| US9326924B1 (en) | 2015-02-26 | 2016-05-03 | Johnson & Johnson Consumer Inc. | Compositions comprising combinations of organic acids |
| US9326925B1 (en) | 2015-02-26 | 2016-05-03 | Johnson & Johnson Consumer Inc. | Compositions comprising combinations of organic acids |
| EP3261610B1 (en) | 2015-02-26 | 2019-12-18 | Johnson & Johnson Consumer Inc. | Compositions comprising combinations of organic acids |
| US9974722B2 (en) | 2016-10-20 | 2018-05-22 | Johnson & Johnson Consumer Inc. | Reduced-ethanol mouth rinse formulations |
| US20190175487A1 (en) | 2017-12-07 | 2019-06-13 | Johnson & Johnson Consumer Inc. | Oral Care Compositions |
| US20190175486A1 (en) | 2017-12-07 | 2019-06-13 | Johnson & Johnson Consumer Inc. | Oral Care Compositions |
| WO2020021481A1 (en) | 2018-07-27 | 2020-01-30 | Johnson & Johnson Vision Care, Inc. | Compositions and methods for treating the eye |
| US11166997B2 (en) | 2018-07-27 | 2021-11-09 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| CA3106898A1 (en) | 2018-07-27 | 2020-01-30 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| CN109010240A (zh) * | 2018-10-25 | 2018-12-18 | 大连丹特生物技术有限公司 | 一种缓解牙齿敏感的药用组合物及其制备方法和应用 |
| US20210023153A1 (en) | 2019-07-23 | 2021-01-28 | Johnson & Johnson Consumer Inc. | Compositions and Methods for Treating the Oral Cavity |
| US11969451B2 (en) | 2019-11-19 | 2024-04-30 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| CN114469863B (zh) * | 2021-11-26 | 2023-09-26 | 南方医科大学南方医院 | 甾醇脂质体作为牙髓和牙本质药物传递系统的应用 |
| GB202214700D0 (en) * | 2022-10-06 | 2022-11-23 | GlaxoSmithKline Consumer Healthcare UK IP Ltd | Dentifrice composition |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3863006A (en) | 1973-01-29 | 1975-01-28 | Milton Hodosh | Method for desensitizing teeth |
| US4767615A (en) | 1984-05-03 | 1988-08-30 | Technology Unlimited, Inc. | Dental therapy by vesicle delivery |
| US4634589A (en) | 1984-05-18 | 1987-01-06 | Wurttembergische Parfumerie-Fabrik Gmbh | Dentifrice for hypersensitive teeth |
| DE3886775T2 (de) * | 1988-08-22 | 1994-04-14 | Technology Unlimited Inc | Zahnbehandlung durch freisetzung von vesikeln. |
| US5104661A (en) * | 1989-08-14 | 1992-04-14 | Technology Unlimited, Inc. | Reverse loading of liposomes |
| GB9022298D0 (en) * | 1990-10-15 | 1990-11-28 | Unilever Plc | Treatment composition |
| AU652778B2 (en) * | 1990-10-15 | 1994-09-08 | Quest International B.V. | Treatment composition |
| FR2676362B3 (fr) * | 1991-05-17 | 1993-08-13 | Oreal | Procede pour accroitre l'activite d'au moins un actif dans une composition a usage cosmetique et/ou dermopharmaceutique et composition pour la mise en óoeuvre dudit procede. |
| US5211939A (en) | 1991-09-13 | 1993-05-18 | Gillette Canada | Method for desensitizing teeth |
| US5270031A (en) | 1991-12-20 | 1993-12-14 | Block Drug Company Inc. | Dentinal desensitizing compositions |
| DE4306475A1 (de) * | 1993-03-02 | 1994-09-08 | Ensenat Pedro Gonzalez | Liposomen, enthaltend Chlorhexidindiacetat oder Chlorhexidindigluconat |
| US5853755A (en) * | 1993-07-28 | 1998-12-29 | Pharmaderm Laboratories Ltd. | Biphasic multilamellar lipid vesicles |
| US5874075A (en) * | 1993-10-06 | 1999-02-23 | Amgen Inc. | Stable protein: phospholipid compositions and methods |
| ATE241394T1 (de) * | 1994-04-08 | 2003-06-15 | Atrix Lab Inc | Beigeordnetes polymersystem zur verwendung mit einer medizinischen vorrichtung |
| FI104881B (fi) | 1994-10-06 | 2000-04-28 | Bioxid Oy | Uusien bioaktiivista piipitoista lasia sisältävien koostumusten valmistusmenetelmä |
| US5589159A (en) | 1995-04-11 | 1996-12-31 | Block Drug Company Inc. | Dispersible particulate system for desensitizing teeth |
| US6261597B1 (en) * | 1995-08-31 | 2001-07-17 | Seymour J. Kurtz | Method for treating periodontal disease |
| US5735942A (en) | 1996-02-07 | 1998-04-07 | Usbiomaterials Corporation | Compositions containing bioactive glass and their use in treating tooth hypersensitivity |
| US6045823A (en) * | 1996-09-19 | 2000-04-04 | Dragoco Gerberding & Co. Ag | Process for producing solid anhydrous composition, and pharmaceutical and cosmetic products comprising same |
| US5935599A (en) * | 1996-10-28 | 1999-08-10 | The Board Of Trustees Of The University Of Illinois | Polymer-associated liposomes for drug delivery and method of manufacturing the same |
| US5922332A (en) * | 1997-09-17 | 1999-07-13 | Fossel; Eric T. | Topical delivery of arginine to overcome pain |
| US6228347B1 (en) * | 1997-12-01 | 2001-05-08 | Thione International, Inc. | Antioxidant gel for gingival conditions |
| AU4143999A (en) * | 1998-05-15 | 1999-12-06 | Unilever Plc | Oral composition comprising capsules |
| DE19922193B4 (de) * | 1999-05-12 | 2004-12-02 | Sonnenberg, Frank, Dipl.-Biol. | Wasserlösliches Konzentrat, bestehend aus ätherischen Ölen mikroverkapselt in einem Liposomensystem, ein Verfahren zu seiner Herstellung und die Verwendung |
| AR030713A1 (es) * | 2000-08-21 | 2003-09-03 | Block Drug Co | Composicion dental para reducir la hipersensibilidad dentinal debida a la presencia de superficie dentinal expuesta y de tubulos dentinales abiertos, uso de una combinacion sinergica de una cantidad desensibilizadora de al menos un agente de bloqueo de los tubulos y un agente desensibilizador del ne |
| US6416745B1 (en) * | 2001-05-03 | 2002-07-09 | Block Drug Company, Inc. | Dental composition for treating hypersensitive teeth |
-
2001
- 2001-05-03 US US09/848,138 patent/US6416745B1/en not_active Expired - Fee Related
-
2002
- 2002-05-03 AU AU2002308581A patent/AU2002308581A1/en not_active Abandoned
- 2002-05-03 JP JP2002586832A patent/JP3946644B2/ja not_active Expired - Fee Related
- 2002-05-03 DE DE60232790T patent/DE60232790D1/de not_active Expired - Lifetime
- 2002-05-03 BR BR0209368-5A patent/BR0209368A/pt not_active IP Right Cessation
- 2002-05-03 WO PCT/US2002/013978 patent/WO2002089690A2/en not_active Ceased
- 2002-05-03 EP EP02769323A patent/EP1390004B1/en not_active Expired - Lifetime
- 2002-05-03 AT AT02769323T patent/ATE435053T1/de not_active IP Right Cessation
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