JP2004523275A - 治療能力のある薬剤の送達 - Google Patents

治療能力のある薬剤の送達 Download PDF

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JP2004523275A
JP2004523275A JP2002557301A JP2002557301A JP2004523275A JP 2004523275 A JP2004523275 A JP 2004523275A JP 2002557301 A JP2002557301 A JP 2002557301A JP 2002557301 A JP2002557301 A JP 2002557301A JP 2004523275 A JP2004523275 A JP 2004523275A
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day
release
therapeutically
compound
therapeutically active
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JP2002557301A
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Japanese (ja)
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JP2004523275A5 (enExample
Inventor
モタシム サーハン
ジョン ヤン
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アバンテク バスキュラー コーポレーション
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27567288&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2004523275(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/783,254 external-priority patent/US20020082678A1/en
Priority claimed from US09/783,253 external-priority patent/US6939375B2/en
Priority claimed from US09/782,927 external-priority patent/US6471980B2/en
Priority claimed from US09/782,804 external-priority patent/US7018405B2/en
Priority claimed from US10/002,595 external-priority patent/US20020082679A1/en
Application filed by アバンテク バスキュラー コーポレーション filed Critical アバンテク バスキュラー コーポレーション
Publication of JP2004523275A publication Critical patent/JP2004523275A/ja
Publication of JP2004523275A5 publication Critical patent/JP2004523275A5/ja
Pending legal-status Critical Current

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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A—HUMAN NECESSITIES
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A—HUMAN NECESSITIES
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    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/0054—V-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Surgery (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
JP2002557301A 2000-12-22 2001-12-18 治療能力のある薬剤の送達 Pending JP2004523275A (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US25802400P 2000-12-22 2000-12-22
US09/783,254 US20020082678A1 (en) 2000-12-22 2001-02-13 Intravascular delivery of mizoribine
US09/783,253 US6939375B2 (en) 2000-12-22 2001-02-13 Apparatus and methods for controlled substance delivery from implanted prostheses
US09/782,927 US6471980B2 (en) 2000-12-22 2001-02-13 Intravascular delivery of mycophenolic acid
US09/782,804 US7018405B2 (en) 2000-12-22 2001-02-13 Intravascular delivery of methylprednisolone
US30838101P 2001-07-26 2001-07-26
US10/002,595 US20020082679A1 (en) 2000-12-22 2001-11-01 Delivery or therapeutic capable agents
PCT/US2001/049366 WO2002056790A2 (en) 2000-12-22 2001-12-18 Delivery of therapeutic capable agents

Publications (2)

Publication Number Publication Date
JP2004523275A true JP2004523275A (ja) 2004-08-05
JP2004523275A5 JP2004523275A5 (enExample) 2005-05-26

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ID=27567288

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Application Number Title Priority Date Filing Date
JP2002557301A Pending JP2004523275A (ja) 2000-12-22 2001-12-18 治療能力のある薬剤の送達

Country Status (6)

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EP (1) EP1355588B1 (enExample)
JP (1) JP2004523275A (enExample)
AT (1) ATE369817T1 (enExample)
AU (1) AU2002249826A1 (enExample)
DE (1) DE60130032D1 (enExample)
WO (1) WO2002056790A2 (enExample)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005521477A (ja) * 2002-03-27 2005-07-21 アドヴァンスド カーディオヴァスキュラー システムズ， インコーポレイテッド ４０−ｏ−（２−ヒドロキシ）エチル−ラパマイシン塗布ステント
WO2006027994A1 (ja) * 2004-09-08 2006-03-16 Kaneka Corporation 生体留置用ステント
WO2006046561A1 (ja) * 2004-10-26 2006-05-04 Asahi Intecc Co., Ltd. 生体内留置器具
JP2007284454A (ja) * 2001-02-19 2007-11-01 Novartis Ag 癌の処置
JPWO2006027994A1 (ja) * 2004-09-08 2008-05-08 株式会社カネカ 生体留置用ステント
JP2009505776A (ja) * 2005-08-30 2009-02-12 ボストン・サイエンティフィク・サイムド・インコーポレーテッド 生体吸収性ステント
JP2009518127A (ja) * 2005-12-06 2009-05-07 タイコ ヘルスケア グループ リミテッド パートナーシップ 生体適合性外科用組成物
JP2009538183A (ja) * 2006-05-22 2009-11-05 アボット カーディオヴァスキュラー システムズ インコーポレイテッド 分解可能な医療デバイス
JP2010520785A (ja) * 2007-03-09 2010-06-17 アイコン メディカル コーポレーション 医療用具用生体吸収性コーティング
WO2011024831A1 (ja) 2009-08-26 2011-03-03 国立大学法人九州大学 管腔内留置用医療デバイス及びその製造方法
JP2013500334A (ja) * 2009-07-29 2013-01-07 メドトロニック，インコーポレイテッド 痛みおよび／または炎症の処置のための可逆的相転移物質を有する埋め込み式薬物デポー
JP2014176740A (ja) * 2005-04-05 2014-09-25 Elixir Medical Corp 分解性の移植可能な医療装置
JP2018531135A (ja) * 2015-10-12 2018-10-25 リフロー メディカル インコーポレイテッド 突出する薬剤送達フィーチャーを有するステント、ならびに、関連のシステムおよび方法
JP2021502859A (ja) * 2017-11-15 2021-02-04 アルキオーネ・ライフサイエンシズ・インコーポレイテッドＡｌｃｙｏｎｅ Ｌｉｆｅｓｃｉｅｎｃｅｓ， Ｉｎｃ． 薬物送達システムおよび方法
US11241322B2 (en) 2014-10-28 2022-02-08 Jimro Co., Ltd. Drug-eluting stent

Families Citing this family (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6776792B1 (en) 1997-04-24 2004-08-17 Advanced Cardiovascular Systems Inc. Coated endovascular stent
US7985415B2 (en) 1997-09-10 2011-07-26 Rutgers, The State University Of New Jersey Medical devices employing novel polymers
US20030129215A1 (en) * 1998-09-24 2003-07-10 T-Ram, Inc. Medical devices containing rapamycin analogs
US6890546B2 (en) * 1998-09-24 2005-05-10 Abbott Laboratories Medical devices containing rapamycin analogs
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6908624B2 (en) 1999-12-23 2005-06-21 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US9320829B2 (en) 2000-03-15 2016-04-26 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US8460367B2 (en) 2000-03-15 2013-06-11 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US6451373B1 (en) 2000-08-04 2002-09-17 Advanced Cardiovascular Systems, Inc. Method of forming a therapeutic coating onto a surface of an implantable prosthesis
AU2001271417B2 (en) 2000-08-30 2006-10-05 Johns Hopkins University Devices for intraocular drug delivery
US6953560B1 (en) 2000-09-28 2005-10-11 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
US6783793B1 (en) 2000-10-26 2004-08-31 Advanced Cardiovascular Systems, Inc. Selective coating of medical devices
US6663662B2 (en) 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
US6780424B2 (en) 2001-03-30 2004-08-24 Charles David Claude Controlled morphologies in polymer drug for release of drugs from polymer films
US6613083B2 (en) † 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US6743462B1 (en) 2001-05-31 2004-06-01 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating implantable devices
US8741378B1 (en) 2001-06-27 2014-06-03 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device
US6565659B1 (en) 2001-06-28 2003-05-20 Advanced Cardiovascular Systems, Inc. Stent mounting assembly and a method of using the same to coat a stent
US7285304B1 (en) 2003-06-25 2007-10-23 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US7223282B1 (en) 2001-09-27 2007-05-29 Advanced Cardiovascular Systems, Inc. Remote activation of an implantable device
US6753071B1 (en) 2001-09-27 2004-06-22 Advanced Cardiovascular Systems, Inc. Rate-reducing membrane for release of an agent
GB0125443D0 (en) 2001-10-23 2001-12-12 Novartis Ag Organic Compounds
US6709514B1 (en) 2001-12-28 2004-03-23 Advanced Cardiovascular Systems, Inc. Rotary coating apparatus for coating implantable medical devices
US7070798B1 (en) 2002-06-21 2006-07-04 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine
US7056523B1 (en) 2002-06-21 2006-06-06 Advanced Cardiovascular Systems, Inc. Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine
US6994867B1 (en) 2002-06-21 2006-02-07 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing L-arginine
US7011842B1 (en) 2002-06-21 2006-03-14 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of making the same
US8506617B1 (en) 2002-06-21 2013-08-13 Advanced Cardiovascular Systems, Inc. Micronized peptide coated stent
US7217426B1 (en) 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
US7033602B1 (en) 2002-06-21 2006-04-25 Advanced Cardiovascular Systems, Inc. Polycationic peptide coatings and methods of coating implantable medical devices
CN1684725A (zh) * 2002-09-26 2005-10-19 血管技术国际股份公司 血管周包裹物
US7087263B2 (en) 2002-10-09 2006-08-08 Advanced Cardiovascular Systems, Inc. Rare limiting barriers for implantable medical devices
US7544678B2 (en) 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
US6896965B1 (en) 2002-11-12 2005-05-24 Advanced Cardiovascular Systems, Inc. Rate limiting barriers for implantable devices
US20040098106A1 (en) * 2002-11-14 2004-05-20 Williams Michael S. Intraluminal prostheses and carbon dioxide-assisted methods of impregnating same with pharmacological agents
JP2006506208A (ja) * 2002-11-15 2006-02-23 サインコア，リミテッド・ライアビリティ・カンパニー ポリマー製体内プロテーゼおよび製造方法
CN1735404A (zh) * 2002-11-18 2006-02-15 波利梅里斯公司 使用新聚合物的医疗装置
US6982004B1 (en) 2002-11-26 2006-01-03 Advanced Cardiovascular Systems, Inc. Electrostatic loading of drugs on implantable medical devices
US7758880B2 (en) 2002-12-11 2010-07-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications
US7776926B1 (en) 2002-12-11 2010-08-17 Advanced Cardiovascular Systems, Inc. Biocompatible coating for implantable medical devices
US7074276B1 (en) 2002-12-12 2006-07-11 Advanced Cardiovascular Systems, Inc. Clamp mandrel fixture and a method of using the same to minimize coating defects
US7094256B1 (en) 2002-12-16 2006-08-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical device containing polycationic peptides
EP2253339B1 (en) 2003-02-21 2011-12-28 Sorin Biomedica Cardio S.r.l. A process for producing stents and corresponding stent
US7063884B2 (en) 2003-02-26 2006-06-20 Advanced Cardiovascular Systems, Inc. Stent coating
US7563483B2 (en) 2003-02-26 2009-07-21 Advanced Cardiovascular Systems Inc. Methods for fabricating a coating for implantable medical devices
US6926919B1 (en) 2003-02-26 2005-08-09 Advanced Cardiovascular Systems, Inc. Method for fabricating a coating for a medical device
US7279174B2 (en) 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
DE10329260A1 (de) * 2003-06-23 2005-01-13 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Stent mit einem Beschichtungssystem
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
US7056591B1 (en) 2003-07-30 2006-06-06 Advanced Cardiovascular Systems, Inc. Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same
US7431959B1 (en) 2003-07-31 2008-10-07 Advanced Cardiovascular Systems Inc. Method and system for irradiation of a drug eluting implantable medical device
CA2533339A1 (en) * 2003-08-05 2005-02-10 Kaneka Corporation Stent to be placed in vivo
US20050060020A1 (en) * 2003-09-17 2005-03-17 Scimed Life Systems, Inc. Covered stent with biologically active material
US7441513B1 (en) 2003-09-26 2008-10-28 Advanced Cardiovascular Systems, Inc. Plasma-generated coating apparatus for medical devices and a method of coating deposition
US7198675B2 (en) 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
US7318932B2 (en) 2003-09-30 2008-01-15 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same
US7329413B1 (en) 2003-11-06 2008-02-12 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
US7560492B1 (en) 2003-11-25 2009-07-14 Advanced Cardiovascular Systems, Inc. Polysulfone block copolymers as drug-eluting coating material
US7220816B2 (en) 2003-12-16 2007-05-22 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same
US7435788B2 (en) 2003-12-19 2008-10-14 Advanced Cardiovascular Systems, Inc. Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
US7563324B1 (en) 2003-12-29 2009-07-21 Advanced Cardiovascular Systems Inc. System and method for coating an implantable medical device
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7553377B1 (en) 2004-04-27 2009-06-30 Advanced Cardiovascular Systems, Inc. Apparatus and method for electrostatic coating of an abluminal stent surface
US8293890B2 (en) 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
US9561309B2 (en) 2004-05-27 2017-02-07 Advanced Cardiovascular Systems, Inc. Antifouling heparin coatings
US7563780B1 (en) 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
US20060009839A1 (en) * 2004-07-12 2006-01-12 Scimed Life Systems, Inc. Composite vascular graft including bioactive agent coating and biodegradable sheath
US20060020328A1 (en) * 2004-07-23 2006-01-26 Tan Sharon M L Composite vascular graft having bioactive agent
US7494665B1 (en) 2004-07-30 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymers containing siloxane monomers
US7311980B1 (en) 2004-08-02 2007-12-25 Advanced Cardiovascular Systems, Inc. Polyactive/polylactic acid coatings for an implantable device
US7244443B2 (en) 2004-08-31 2007-07-17 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrophilic monomers
US7901451B2 (en) 2004-09-24 2011-03-08 Biosensors International Group, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US7166680B2 (en) 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
US8603634B2 (en) 2004-10-27 2013-12-10 Abbott Cardiovascular Systems Inc. End-capped poly(ester amide) copolymers
US7390497B2 (en) 2004-10-29 2008-06-24 Advanced Cardiovascular Systems, Inc. Poly(ester amide) filler blends for modulation of coating properties
US7481835B1 (en) 2004-10-29 2009-01-27 Advanced Cardiovascular Systems, Inc. Encapsulated covered stent
US7214759B2 (en) 2004-11-24 2007-05-08 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
US7588642B1 (en) 2004-11-29 2009-09-15 Advanced Cardiovascular Systems, Inc. Abluminal stent coating apparatus and method using a brush assembly
US7632307B2 (en) 2004-12-16 2009-12-15 Advanced Cardiovascular Systems, Inc. Abluminal, multilayer coating constructs for drug-delivery stents
US7604818B2 (en) 2004-12-22 2009-10-20 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrocarbon monomers
US7419504B2 (en) 2004-12-27 2008-09-02 Advanced Cardiovascular Systems, Inc. Poly(ester amide) block copolymers
US7202325B2 (en) 2005-01-14 2007-04-10 Advanced Cardiovascular Systems, Inc. Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles
EP1846505B1 (en) 2005-02-09 2015-11-11 Covidien LP Synthetic sealants
US8044234B2 (en) 2005-05-05 2011-10-25 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US7637941B1 (en) 2005-05-11 2009-12-29 Advanced Cardiovascular Systems, Inc. Endothelial cell binding coatings for rapid encapsulation of bioerodable stents
US7622070B2 (en) 2005-06-20 2009-11-24 Advanced Cardiovascular Systems, Inc. Method of manufacturing an implantable polymeric medical device
US9028467B2 (en) 2005-11-09 2015-05-12 The Invention Science Fund I, Llc Osmotic pump with remotely controlled osmotic pressure generation
US9067047B2 (en) 2005-11-09 2015-06-30 The Invention Science Fund I, Llc Injectable controlled release fluid delivery system
US8998884B2 (en) 2005-11-09 2015-04-07 The Invention Science Fund I, Llc Remote controlled in situ reaction method
US8992511B2 (en) 2005-11-09 2015-03-31 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US8273071B2 (en) 2006-01-18 2012-09-25 The Invention Science Fund I, Llc Remote controller for substance delivery system
US8083710B2 (en) 2006-03-09 2011-12-27 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US7942867B2 (en) 2005-11-09 2011-05-17 The Invention Science Fund I, Llc Remotely controlled substance delivery device
US8936590B2 (en) 2005-11-09 2015-01-20 The Invention Science Fund I, Llc Acoustically controlled reaction device
US20070112421A1 (en) * 2005-11-14 2007-05-17 O'brien Barry Medical device with a grooved surface
JP5088894B2 (ja) 2005-12-06 2012-12-05 タイコ ヘルスケア グループ リミテッド パートナーシップ 生体適合性組織封止剤および接着剤
WO2007067622A2 (en) 2005-12-06 2007-06-14 Tyco Healthcare Group Lp Carbodiimide crosslinking of functionalized polethylene glycols
EP1960447A4 (en) 2005-12-08 2010-12-01 Tyco Healthcare BIOCOMPATIBLE SURGICAL COMPOSITIONS
US7591841B2 (en) 2005-12-16 2009-09-22 Advanced Cardiovascular Systems, Inc. Implantable devices for accelerated healing
US7638156B1 (en) 2005-12-19 2009-12-29 Advanced Cardiovascular Systems, Inc. Apparatus and method for selectively coating a medical article
US7601383B2 (en) 2006-02-28 2009-10-13 Advanced Cardiovascular Systems, Inc. Coating construct containing poly (vinyl alcohol)
US20080140057A1 (en) 2006-03-09 2008-06-12 Searete Llc, A Limited Liability Corporation Of State Of The Delaware Injectable controlled release fluid delivery system
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
EP2012794B1 (en) * 2006-04-13 2014-09-17 The Trustees of Columbia University in the City of New York Compositions and intraluminal devices for inhibiting vascular stenosis
US9561351B2 (en) 2006-05-31 2017-02-07 Advanced Cardiovascular Systems, Inc. Drug delivery spiral coil construct
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
JP2009542359A (ja) 2006-06-29 2009-12-03 ボストン サイエンティフィック リミテッド 選択的被覆部を備えた医療装置
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
CN101557814B (zh) 2006-09-13 2015-05-20 万能医药公司 大环内酯化合物及它们的使用方法
US8088789B2 (en) 2006-09-13 2012-01-03 Elixir Medical Corporation Macrocyclic lactone compounds and methods for their use
US10695327B2 (en) 2006-09-13 2020-06-30 Elixir Medical Corporation Macrocyclic lactone compounds and methods for their use
WO2008033711A2 (en) 2006-09-14 2008-03-20 Boston Scientific Limited Medical devices with drug-eluting coating
US20080097591A1 (en) 2006-10-20 2008-04-24 Biosensors International Group Drug-delivery endovascular stent and method of use
US8067055B2 (en) * 2006-10-20 2011-11-29 Biosensors International Group, Ltd. Drug-delivery endovascular stent and method of use
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US9056155B1 (en) 2007-05-29 2015-06-16 Abbott Cardiovascular Systems Inc. Coatings having an elastic primer layer
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US9284409B2 (en) 2007-07-19 2016-03-15 Boston Scientific Scimed, Inc. Endoprosthesis having a non-fouling surface
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US8221822B2 (en) 2007-07-31 2012-07-17 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
JP2010535541A (ja) 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド 広い表面積を有する医療器具用のコーティング
CN101411878B (zh) * 2007-10-17 2010-09-22 中国科学院化学研究所 一种在生物降解性材料上锚定生长因子的方法
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
JP5581311B2 (ja) 2008-04-22 2014-08-27 ボストン サイエンティフィック サイムド，インコーポレイテッド 無機材料のコーティングを有する医療デバイス及びその製造方法
US8263704B2 (en) 2008-04-23 2012-09-11 Tyco Healthcare Group Lp Bioabsorbable surgical composition
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
KR101104901B1 (ko) * 2008-05-23 2012-01-12 김영곤 능동 약물 방출형 서모 로드의 제조방법 및 이에 의해제조된 서모 로드
WO2009155328A2 (en) 2008-06-18 2009-12-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US8685433B2 (en) 2010-03-31 2014-04-01 Abbott Cardiovascular Systems Inc. Absorbable coating for implantable device
WO2012095865A2 (en) * 2011-01-11 2012-07-19 Manish Doshi Biodegradable medical devices and method to control degradation of the biodegradable medical devices
US9700441B2 (en) 2012-10-31 2017-07-11 W. L. Gore & Associates, Inc. Devices and methods related to deposited support structures
US10959715B2 (en) 2012-10-31 2021-03-30 W. L. Gore & Associates, Inc. Devices and methods related to deposited support structures
US11744594B2 (en) 2012-11-16 2023-09-05 W.L. Gore & Associates, Inc. Space filling devices
EP3589243B1 (en) 2017-02-28 2024-09-11 University College Cork - National University of Ireland, Cork An intravascular cell therapy device
WO2019147613A1 (en) * 2018-01-23 2019-08-01 The Regents Of The University Of California Downstream delivery of agents in solid organ transplantation
DE102019132549B4 (de) * 2019-11-29 2022-04-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Immunmodulatoranordnung zur Behandlung von Krebserkrankungen und Verfahren zur topischen Einkopplung von in Betrag und Richtung wechselnder Energie
US12133936B2 (en) 2021-01-06 2024-11-05 Medtronic, Inc Surgical system and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0533816B1 (en) * 1990-06-15 1995-06-14 Cortrak Medical, Inc. Drug delivery apparatus
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US5419760A (en) * 1993-01-08 1995-05-30 Pdt Systems, Inc. Medicament dispensing stent for prevention of restenosis of a blood vessel
US5464650A (en) * 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US6299604B1 (en) * 1998-08-20 2001-10-09 Cook Incorporated Coated implantable medical device

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007284454A (ja) * 2001-02-19 2007-11-01 Novartis Ag 癌の処置
JP2005521477A (ja) * 2002-03-27 2005-07-21 アドヴァンスド カーディオヴァスキュラー システムズ， インコーポレイテッド ４０−ｏ−（２−ヒドロキシ）エチル−ラパマイシン塗布ステント
US8961588B2 (en) 2002-03-27 2015-02-24 Advanced Cardiovascular Systems, Inc. Method of coating a stent with a release polymer for 40-O-(2-hydroxy)ethyl-rapamycin
US8173199B2 (en) 2002-03-27 2012-05-08 Advanced Cardiovascular Systems, Inc. 40-O-(2-hydroxy)ethyl-rapamycin coated stent
JP4894519B2 (ja) * 2004-09-08 2012-03-14 株式会社カネカ 生体留置用ステント
WO2006027994A1 (ja) * 2004-09-08 2006-03-16 Kaneka Corporation 生体留置用ステント
JPWO2006027994A1 (ja) * 2004-09-08 2008-05-08 株式会社カネカ 生体留置用ステント
WO2006046561A1 (ja) * 2004-10-26 2006-05-04 Asahi Intecc Co., Ltd. 生体内留置器具
JP2014176740A (ja) * 2005-04-05 2014-09-25 Elixir Medical Corp 分解性の移植可能な医療装置
JP2009505776A (ja) * 2005-08-30 2009-02-12 ボストン・サイエンティフィク・サイムド・インコーポレーテッド 生体吸収性ステント
JP2009518127A (ja) * 2005-12-06 2009-05-07 タイコ ヘルスケア グループ リミテッド パートナーシップ 生体適合性外科用組成物
JP2009538183A (ja) * 2006-05-22 2009-11-05 アボット カーディオヴァスキュラー システムズ インコーポレイテッド 分解可能な医療デバイス
JP2010520785A (ja) * 2007-03-09 2010-06-17 アイコン メディカル コーポレーション 医療用具用生体吸収性コーティング
JP2013500334A (ja) * 2009-07-29 2013-01-07 メドトロニック，インコーポレイテッド 痛みおよび／または炎症の処置のための可逆的相転移物質を有する埋め込み式薬物デポー
WO2011024831A1 (ja) 2009-08-26 2011-03-03 国立大学法人九州大学 管腔内留置用医療デバイス及びその製造方法
US11241322B2 (en) 2014-10-28 2022-02-08 Jimro Co., Ltd. Drug-eluting stent
JP2018531135A (ja) * 2015-10-12 2018-10-25 リフロー メディカル インコーポレイテッド 突出する薬剤送達フィーチャーを有するステント、ならびに、関連のシステムおよび方法
US11253379B2 (en) 2015-10-12 2022-02-22 Reflow Medical, Inc. Stents having protruding drug-delivery features and associated systems and methods
JP2021502859A (ja) * 2017-11-15 2021-02-04 アルキオーネ・ライフサイエンシズ・インコーポレイテッドＡｌｃｙｏｎｅ Ｌｉｆｅｓｃｉｅｎｃｅｓ， Ｉｎｃ． 薬物送達システムおよび方法
JP7322017B2 (ja) 2017-11-15 2023-08-07 アルキオーネ セラピューティクス、インコーポレイテッド 薬物送達システムおよび方法

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