JP2004521964A5 - - Google Patents
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- JP2004521964A5 JP2004521964A5 JP2003542156A JP2003542156A JP2004521964A5 JP 2004521964 A5 JP2004521964 A5 JP 2004521964A5 JP 2003542156 A JP2003542156 A JP 2003542156A JP 2003542156 A JP2003542156 A JP 2003542156A JP 2004521964 A5 JP2004521964 A5 JP 2004521964A5
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- JP
- Japan
- Prior art keywords
- compound
- methoxyphenyl
- triazole
- mmol
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000003839 salts Chemical class 0.000 claims description 26
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- 125000003545 alkoxy group Chemical group 0.000 claims description 8
- 229910052736 halogen Inorganic materials 0.000 claims description 7
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- JGNJBTJUEOKTJR-UHFFFAOYSA-N 1,5-bis(4-methoxyphenyl)-3-propan-2-yloxy-1,2,4-triazole Chemical compound C1=CC(OC)=CC=C1C1=NC(OC(C)C)=NN1C1=CC=C(OC)C=C1 JGNJBTJUEOKTJR-UHFFFAOYSA-N 0.000 claims description 2
- GRGAGIRZLRLUOU-UHFFFAOYSA-N 3-(fluoromethoxy)-1,5-bis(4-methoxyphenyl)-1,2,4-triazole Chemical compound C1=CC(OC)=CC=C1C1=NC(OCF)=NN1C1=CC=C(OC)C=C1 GRGAGIRZLRLUOU-UHFFFAOYSA-N 0.000 claims description 2
- LWBGBGKQKIMGQC-UHFFFAOYSA-N 3-ethoxy-1,5-bis(4-methoxyphenyl)-1,2,4-triazole Chemical compound C=1C=C(OC)C=CC=1N1N=C(OCC)N=C1C1=CC=C(OC)C=C1 LWBGBGKQKIMGQC-UHFFFAOYSA-N 0.000 claims description 2
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| WO2012170839A2 (en) * | 2011-06-09 | 2012-12-13 | Cardeus Pharmaceuticals, Inc. | Treatment of neuroinflammatory disease with selective cox1 inhibitors |
| EA201590916A1 (ru) * | 2012-11-09 | 2016-02-29 | Корнэлл Юниверсити | Низкомолекулярные ингибиторы malt1 |
| CN113329754A (zh) | 2018-11-20 | 2021-08-31 | 麻雀制药股份有限公司 | 用于施用皮质类固醇的方法 |
| CN115611901B (zh) * | 2021-07-16 | 2024-04-30 | 华南理工大学 | 一种氮杂䓬类化合物或其药学上可接受的盐及其制备方法和应用 |
| IL316907A (en) | 2022-05-16 | 2025-01-01 | Sparrow Pharmaceuticals Inc | METHODS AND COMPOSITIONS FOR TREATING GLUCOCORTICOD EXCESS |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0051084A1 (en) | 1980-11-04 | 1982-05-12 | American Cyanamid Company | Substituted 1H-1,2,4-triazoles |
| HU193891B (en) * | 1984-02-07 | 1987-12-28 | Gyogyszerkutato Intezet | Process for production of new derivatives of 1,2,4-triasole |
| FI850995A7 (fi) | 1984-03-16 | 1985-09-17 | Ciba Geigy Ag | Menetelmä uusien 3-merkapto-1,2,4 -triatsasykloalkadieenijohdannaisten valmistamiseksi. |
| FI850994L (fi) | 1984-03-16 | 1985-09-17 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya 1,2,4-triazacykloalkadienderivat. |
| AU581216B2 (en) | 1984-04-17 | 1989-02-16 | Henkel Corporation | Production of d-alpha-tocopherol from natural plant sources |
| JPS60233066A (ja) * | 1984-05-07 | 1985-11-19 | Nippon Nohyaku Co Ltd | １．５−ジフエニルトリアゾ−ル誘導体及びその製造方法 |
| CA2327185A1 (en) | 1998-04-08 | 1999-10-14 | Abbott Laboratories | Pyrazole inhibitors of cytokine production |
| ES2221426T3 (es) | 1998-08-20 | 2004-12-16 | Smithkline Beecham Corporation | Nuevos compuestos de triazol sustituidos. |
| EP1099695A1 (en) | 1999-11-09 | 2001-05-16 | Laboratoire Theramex S.A. | 5-aryl-1H-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them |
| AUPR878201A0 (en) * | 2001-11-09 | 2001-12-06 | Fujisawa Pharmaceutical Co., Ltd. | New compounds |
-
2001
- 2001-11-09 AU AUPR8782A patent/AUPR878201A0/en not_active Abandoned
-
2002
- 2002-10-25 TW TW091124998A patent/TWI300713B/zh not_active IP Right Cessation
- 2002-10-30 AT AT02779943T patent/ATE427940T1/de active
- 2002-10-30 PT PT02779943T patent/PT1442026E/pt unknown
- 2002-10-30 DE DE60231897T patent/DE60231897D1/de not_active Expired - Lifetime
- 2002-10-30 DK DK02779943T patent/DK1442026T3/da active
- 2002-10-30 KR KR10-2003-7002474A patent/KR100511884B1/ko not_active Expired - Fee Related
- 2002-10-30 US US10/344,416 patent/US6927230B2/en not_active Expired - Lifetime
- 2002-10-30 CA CA2465757A patent/CA2465757C/en not_active Expired - Fee Related
- 2002-10-30 CN CNB028269004A patent/CN100338042C/zh not_active Expired - Fee Related
- 2002-10-30 ES ES02779943T patent/ES2325318T3/es not_active Expired - Lifetime
- 2002-10-30 EP EP02779943A patent/EP1442026B9/en not_active Expired - Lifetime
- 2002-10-30 JP JP2003542156A patent/JP3972208B2/ja not_active Expired - Fee Related
- 2002-10-30 WO PCT/JP2002/011314 patent/WO2003040110A1/en not_active Ceased
- 2002-11-08 AR ARP020104295A patent/AR037347A1/es not_active Application Discontinuation
-
2007
- 2007-02-02 JP JP2007024703A patent/JP2007169290A/ja not_active Withdrawn
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