JP2004521960A5 - - Google Patents
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- Publication number
- JP2004521960A5 JP2004521960A5 JP2003522543A JP2003522543A JP2004521960A5 JP 2004521960 A5 JP2004521960 A5 JP 2004521960A5 JP 2003522543 A JP2003522543 A JP 2003522543A JP 2003522543 A JP2003522543 A JP 2003522543A JP 2004521960 A5 JP2004521960 A5 JP 2004521960A5
- Authority
- JP
- Japan
- Prior art keywords
- keto
- prostaglandin compound
- dihydro
- alkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 125000001931 aliphatic group Chemical group 0.000 claims 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 125000003118 aryl group Chemical group 0.000 claims 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
- 125000004043 oxo group Chemical group O=* 0.000 claims 4
- 229920006395 saturated elastomer Polymers 0.000 claims 4
- -1 13,14-dihydro-15-keto-prostaglandin compound Chemical class 0.000 claims 2
- 208000010412 Glaucoma Diseases 0.000 claims 2
- 206010030043 Ocular hypertension Diseases 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000004104 aryloxy group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 125000005843 halogen group Chemical group 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 2
- 125000004434 sulfur atom Chemical group 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31411001P | 2001-08-23 | 2001-08-23 | |
| PCT/JP2002/008446 WO2003018025A1 (en) | 2001-08-23 | 2002-08-22 | Method and composition for treatment of ocular hypertension and glaucoma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004521960A JP2004521960A (ja) | 2004-07-22 |
| JP2004521960A5 true JP2004521960A5 (enExample) | 2005-03-17 |
Family
ID=23218598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003522543A Withdrawn JP2004521960A (ja) | 2001-08-23 | 2002-08-22 | 高眼圧症および緑内障の処置のための方法および組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20030060511A1 (enExample) |
| EP (1) | EP1420793A1 (enExample) |
| JP (1) | JP2004521960A (enExample) |
| KR (1) | KR20040029012A (enExample) |
| CN (1) | CN1575178A (enExample) |
| AR (1) | AR036276A1 (enExample) |
| BR (1) | BR0205932A (enExample) |
| CA (1) | CA2458230A1 (enExample) |
| MX (1) | MXPA04001604A (enExample) |
| NO (1) | NO20031779D0 (enExample) |
| WO (1) | WO2003018025A1 (enExample) |
| ZA (1) | ZA200302911B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003082257A2 (en) * | 2002-03-28 | 2003-10-09 | Sucampo Ag | Method for treating ocular hypertension and glaucoma |
| AR043161A1 (es) * | 2003-02-14 | 2005-07-20 | Sucampo Pharmaceuticals Inc | Composicion oftalmica para tratar hipertension ocular y glaucoma |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| WO2012137987A1 (en) * | 2011-04-07 | 2012-10-11 | Sucampo Ag | Method for treating asthenopia |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932389A (en) * | 1974-12-11 | 1976-01-13 | Pfizer Inc. | 2-Descarboxy-2-(tetrazol-5-yl)-11-desoxy-15-substituted-.omega.-pentanorprostaglandins |
| US5212200A (en) * | 1987-09-18 | 1993-05-18 | R-Tech Ueno, Ltd. | Ocular hypotensive agents |
| US5296504A (en) * | 1988-09-06 | 1994-03-22 | Kabi Pharmacia | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| EP0569046B1 (en) * | 1988-09-06 | 2002-11-13 | Pharmacia Aktiebolag | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| US5321128A (en) * | 1988-09-06 | 1994-06-14 | Kabi Pharmacia Ab | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| US6187813B1 (en) * | 1990-04-10 | 2001-02-13 | Pharmacia & Upjohn Aktiebolag | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| ATE162074T1 (de) * | 1988-10-01 | 1998-01-15 | R Tech Ueno Ltd | Oculare hypotensive mittel |
| US5194429A (en) * | 1988-10-01 | 1993-03-16 | K.K. Ueno Seiyaku Oyo Kenkyujo | Ocular hypotensive agents |
| TW249226B (enExample) * | 1990-04-04 | 1995-06-11 | Aderk Ueno Kk | |
| US5208256A (en) * | 1990-05-22 | 1993-05-04 | R-Tech Ueno, Ltd. | Treatment of ocular hypertension with a synergistic combination for ocular administration |
| CA2046069C (en) * | 1990-07-10 | 2002-04-09 | Ryuji Ueno | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds |
| AU687906B2 (en) * | 1993-12-15 | 1998-03-05 | Alcon Laboratories, Inc. | Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension |
| TW420611B (en) * | 1995-03-10 | 2001-02-01 | R Tech Ueno Ltd | Pharmaceutical composition containing prostanoic acid compounds for the treatment of optic nerve disorder |
| AU7680096A (en) * | 1995-12-22 | 1997-07-17 | Alcon Laboratories, Inc. | Combinations of dp and fp type prostaglandins for lowering iop |
| US6458836B1 (en) * | 2000-03-16 | 2002-10-01 | Sucampo, A.G. | Treatment of ocular hypertension and glaucoma |
| US20020035148A1 (en) * | 2000-07-20 | 2002-03-21 | Ryuji Ueno | Treatment of ocular hypertension |
-
2002
- 2002-08-22 MX MXPA04001604A patent/MXPA04001604A/es unknown
- 2002-08-22 CA CA002458230A patent/CA2458230A1/en not_active Abandoned
- 2002-08-22 CN CNA028209214A patent/CN1575178A/zh active Pending
- 2002-08-22 KR KR10-2004-7002670A patent/KR20040029012A/ko not_active Withdrawn
- 2002-08-22 BR BR0205932-0A patent/BR0205932A/pt not_active Application Discontinuation
- 2002-08-22 WO PCT/JP2002/008446 patent/WO2003018025A1/en not_active Ceased
- 2002-08-22 AR ARP020103150A patent/AR036276A1/es unknown
- 2002-08-22 JP JP2003522543A patent/JP2004521960A/ja not_active Withdrawn
- 2002-08-22 EP EP02760691A patent/EP1420793A1/en not_active Withdrawn
- 2002-08-22 US US10/224,923 patent/US20030060511A1/en not_active Abandoned
-
2003
- 2003-04-14 ZA ZA200302911A patent/ZA200302911B/xx unknown
- 2003-04-22 NO NO20031779A patent/NO20031779D0/no not_active Application Discontinuation
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