JP2004519475A5 - - Google Patents
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- Publication number
- JP2004519475A5 JP2004519475A5 JP2002567137A JP2002567137A JP2004519475A5 JP 2004519475 A5 JP2004519475 A5 JP 2004519475A5 JP 2002567137 A JP2002567137 A JP 2002567137A JP 2002567137 A JP2002567137 A JP 2002567137A JP 2004519475 A5 JP2004519475 A5 JP 2004519475A5
- Authority
- JP
- Japan
- Prior art keywords
- interferon
- pharmaceutical composition
- composition according
- antibody
- antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26054101P | 2001-01-09 | 2001-01-09 | |
| PCT/US2002/000343 WO2002067760A2 (en) | 2001-01-09 | 2002-01-08 | Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009063336A Division JP2009132736A (ja) | 2001-01-09 | 2009-03-16 | 対象における自己免疫疾患の治療法及びinvitro診断アッセイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004519475A JP2004519475A (ja) | 2004-07-02 |
| JP2004519475A5 true JP2004519475A5 (https=) | 2007-05-10 |
| JP4394350B2 JP4394350B2 (ja) | 2010-01-06 |
Family
ID=22989575
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567137A Expired - Fee Related JP4394350B2 (ja) | 2001-01-09 | 2002-01-08 | 対象における自己免疫疾患の治療法及びinvitro診断アッセイ |
| JP2009063336A Withdrawn JP2009132736A (ja) | 2001-01-09 | 2009-03-16 | 対象における自己免疫疾患の治療法及びinvitro診断アッセイ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009063336A Withdrawn JP2009132736A (ja) | 2001-01-09 | 2009-03-16 | 対象における自己免疫疾患の治療法及びinvitro診断アッセイ |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US7544357B2 (https=) |
| EP (2) | EP2236156A3 (https=) |
| JP (2) | JP4394350B2 (https=) |
| KR (1) | KR100951409B1 (https=) |
| CN (2) | CN101612402A (https=) |
| AT (1) | ATE502648T1 (https=) |
| AU (1) | AU2002246955B2 (https=) |
| BR (1) | BR0206364A (https=) |
| CA (1) | CA2433806C (https=) |
| DE (1) | DE60239522D1 (https=) |
| DK (1) | DK1351707T3 (https=) |
| ES (1) | ES2363761T3 (https=) |
| MX (1) | MXPA03006100A (https=) |
| WO (1) | WO2002067760A2 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0206364A (pt) * | 2001-01-09 | 2005-08-16 | Baylor Res Inst | Métodos para tratar doenças auto-imunes em um indivìduo e testes diagnósticos in vitro |
| WO2005060992A1 (en) * | 2003-12-24 | 2005-07-07 | The Walter And Eliza Hall Institute Of Medical Research | Therapeutic agents and uses therefor |
| HUE035082T2 (en) | 2004-06-21 | 2018-05-02 | Squibb & Sons Llc | Interferon alpha receptor 1 antibodies and their use |
| CN103251953A (zh) * | 2004-07-19 | 2013-08-21 | 约翰·霍普金斯大学 | 供免疫抑制的flt3抑制剂 |
| BRPI0516470A (pt) * | 2004-10-07 | 2008-09-09 | Universitot Zuerich | uso de um agente de bloqueio do interferon tipo i, e, método de prevenção e tratamento da psorìase |
| US7888481B2 (en) * | 2005-02-10 | 2011-02-15 | Baylor Research Institute | Anti-interferon alpha monoclonal antibodies and methods for use |
| WO2006086586A2 (en) * | 2005-02-10 | 2006-08-17 | Baylor Research Institute | Anti-interferon alpha monoclonal antibodies and methods for use |
| EP2076590A4 (en) * | 2007-05-03 | 2011-06-01 | Medimmune Llc | SELF-IMMUNE DISEASE SELF-ANTIBODY MARKERS |
| DK2240781T3 (en) | 2008-01-18 | 2018-03-26 | Harvard College | METHODS FOR DETECTING DISEASE OR STATE SIGNATURES IN BODY FLUIDS |
| HRP20160855T1 (hr) | 2008-02-08 | 2016-09-23 | Medimmune, Llc | Anti-ifnar1 protutijela sa smanjenim afinitetom fc liganda |
| MX2010012052A (es) | 2008-05-07 | 2010-12-14 | Novo Nordisk As | Anticuerpos humanizados contra interferon-alfa humano. |
| WO2010055510A2 (en) * | 2008-11-12 | 2010-05-20 | Yeda Research And Development Co. Ltd. | Diagnosis of multiple sclerosis |
| CN101812119B (zh) * | 2009-02-25 | 2012-02-01 | 上海荣盛生物药业有限公司 | 与免疫抗体相结合的多肽及其应用 |
| CA2806304A1 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting prenatal or pregnancy-related diseases or conditions |
| AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
| EP2596134B1 (en) | 2010-07-23 | 2020-04-08 | President and Fellows of Harvard College | Methods of detecting diseases or conditions using phagocytic cells |
| CN103384824B (zh) * | 2010-12-06 | 2016-02-03 | Thd股份公司 | 癌症诊断方法及其用途 |
| US9823246B2 (en) | 2011-12-28 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon |
| EP2749639B1 (en) * | 2012-02-10 | 2016-10-12 | Hakushinkouseikai Foundation | Proliferating agent for monocyte, culture medium for proliferating monocyte, method for producing monocyte, method for producing dendritic cell, and method for producing dendritic cell vaccine |
| EP2965077B1 (en) | 2013-03-09 | 2022-07-13 | Harry Stylli | Methods of detecting cancer |
| US11585814B2 (en) | 2013-03-09 | 2023-02-21 | Immunis.Ai, Inc. | Methods of detecting prostate cancer |
| KR101536697B1 (ko) * | 2013-11-29 | 2015-07-14 | 아주대학교산학협력단 | 베체트병 진단용 조성물 |
| MA40636A (fr) | 2014-09-11 | 2015-09-11 | Colleen Kelly | Procédés pour détecter le cancer de la prostate |
| EP3215846B1 (en) | 2014-11-05 | 2020-03-11 | Nirmidas Biotech, Inc. | Metal composites for enhanced imaging |
| JP7308034B2 (ja) | 2016-07-01 | 2023-07-13 | リゾルブ セラピューティクス, エルエルシー | 最適化二重ヌクレアーゼ融合物および方法 |
| BR112020003670A2 (pt) | 2017-08-22 | 2020-09-01 | Sanabio, Llc | receptores de interferon solúveis e usos dos mesmos |
| WO2019160976A1 (en) * | 2018-02-14 | 2019-08-22 | Viela Bio, Inc. | Antibodies to feline mcdonough sarcoma (fms)-like tyrosine kinase 3 receptor ligand (flt3l) and uses thereof for treating autoimmune and inflammatory diseases |
| WO2019204634A1 (en) * | 2018-04-20 | 2019-10-24 | Stc. Unm | Rap1-gtp, rac1-gtp and fms-like tyrosine kinase 3 ligand (flt3-l) as biomarkers for early detection of sepsis |
| WO2019241158A1 (en) * | 2018-06-11 | 2019-12-19 | Univerity Of Washington | Compositions and methods for treating inflammatory diseases |
| CN113238061B (zh) * | 2021-07-09 | 2021-10-01 | 中南大学湘雅医院 | 以cd180阴性b细胞指示重症肌无力病情的试剂盒及应用 |
| CN115032396B (zh) * | 2022-06-29 | 2025-02-21 | 深圳市康尔诺生物技术有限公司 | 一种用于预测或判断受试者的肿瘤免疫治疗效果的生物标志物及其应用 |
| CN115678982A (zh) * | 2022-09-09 | 2023-02-03 | 中山大学 | 一种用于慢性自身免疫病诊断和/或病种判断的试剂盒 |
| TW202430564A (zh) * | 2022-10-20 | 2024-08-01 | 英商葛蘭素史密斯克藍智慧財產權有限公司 | 抗原結合蛋白 |
| WO2025015182A2 (en) * | 2023-07-12 | 2025-01-16 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Compositions and methods for treatment of autoimmunity |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423147A (en) * | 1980-04-11 | 1983-12-27 | Secher David S | Monoclonal antibody to interferon-α |
| NZ198445A (en) * | 1980-09-25 | 1984-05-31 | Genentech Inc | Production of human fibroblast interferon by recombinant dna technology |
| US4414150A (en) * | 1980-11-10 | 1983-11-08 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US4456748A (en) * | 1981-02-23 | 1984-06-26 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US4605394A (en) * | 1982-12-03 | 1986-08-12 | Simon V. Skurkovich | Methods for the treatment of pathological conditions by removing interferon from the organism |
| US4362155A (en) * | 1981-03-24 | 1982-12-07 | Skurkovich Simon V | Method and apparatus for the treatment of autoimmune and allergic diseases |
| US4824432A (en) * | 1981-03-24 | 1989-04-25 | S.V.S. Laboratories, Inc. | Method for treating AIDS and other immune deficiencies and immune disorders |
| DE3211263A1 (de) * | 1981-03-31 | 1983-01-27 | Otsuka Pharmaceutical Co. Ltd., Tokyo | Human-interferon verwandte peptide, antigene und antikoerper, sowie verfahren zu deren herstellung |
| US4678751A (en) * | 1981-09-25 | 1987-07-07 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US5096705A (en) * | 1981-10-19 | 1992-03-17 | Genentech, Inc. | Human immune interferon |
| AU561343B2 (en) * | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
| US5582824A (en) * | 1981-10-19 | 1996-12-10 | Genentech, Inc. | Recombinant DES-CYS-TYR-CYS human immune interferon |
| US5827694A (en) * | 1982-03-08 | 1998-10-27 | Genentech, Inc. | DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides |
| US5831023A (en) * | 1982-11-01 | 1998-11-03 | Genentech, Inc. | Recombinant animal interferon polypeptides |
| US4534906A (en) * | 1982-11-01 | 1985-08-13 | Genentech, Inc. | Removal of impurities from human leukocyte interferon preparations |
| EP0139676B1 (en) * | 1983-02-04 | 1992-11-25 | Cytoclonal Pharmaceutics Inc. | Production and characterization of hybridoma antibodies directed specifically against common determinant(s) present among closely related, but distinct proteins |
| GB2148299B (en) * | 1983-09-01 | 1988-01-06 | Hybritech Inc | Antibody compositions of therapeutic agents having an extended serum half-life |
| US4855238A (en) * | 1983-12-16 | 1989-08-08 | Genentech, Inc. | Recombinant gamma interferons having enhanced stability and methods therefor |
| US5082658A (en) * | 1984-01-16 | 1992-01-21 | Genentech, Inc. | Gamma interferon-interleukin-2 synergism |
| FR2560212B1 (fr) * | 1984-02-24 | 1989-12-29 | Unicet | Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps |
| US4650674A (en) * | 1984-07-05 | 1987-03-17 | Genentech, Inc. | Synergistic cytotoxic composition |
| US5196323A (en) * | 1985-04-27 | 1993-03-23 | Boehringer Ingelheim International Gmbh | Process for preparing and purifying alpha-interferon |
| US4828830A (en) * | 1986-01-24 | 1989-05-09 | Genentech, Inc. | Method and composition for prophylaxis and treatment of viral infections |
| JPS6330426A (ja) * | 1986-07-25 | 1988-02-09 | Mitsubishi Chem Ind Ltd | 自己免疫性疾患治療薬 |
| US4851219A (en) * | 1986-11-18 | 1989-07-25 | Genentech, Inc. | Method for the treatment of chronic myelogenous leukemia |
| US4987071A (en) * | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US4944941A (en) * | 1987-08-07 | 1990-07-31 | Genentech, Inc. | Methods and compositions for the treatment of lung conditions |
| US5254678A (en) * | 1987-12-15 | 1993-10-19 | Gene Shears Pty. Limited | Ribozymes |
| AU2844889A (en) | 1988-01-22 | 1989-07-27 | Collagen Corporation | Method for suppressing the growth of normal and cancer cells |
| CA1340323C (en) | 1988-09-20 | 1999-01-19 | Arnold E. Hampel | Rna catalyst for cleaving specific rna sequences |
| US5168053A (en) * | 1989-03-24 | 1992-12-01 | Yale University | Cleavage of targeted RNA by RNAase P |
| US5889151A (en) * | 1989-10-20 | 1999-03-30 | Societe Leb-Tech | Purified human alpha interferon receptor |
| US5919452A (en) * | 1991-03-18 | 1999-07-06 | New York University | Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies |
| AU653937B2 (en) * | 1991-04-17 | 1994-10-20 | Medisup International N.V. | Water-soluble polypeptides having high affinity for interferons alpha and beta |
| US5227158A (en) * | 1991-06-10 | 1993-07-13 | Genentech, Inc. | Method of stimulating hepatocyte proliferation by administration of hepatocyte growth factor and gamma-interferon |
| JPH06510061A (ja) * | 1991-08-30 | 1994-11-10 | ジェネンテク,インコーポレイテッド | Iddmの治療法 |
| US5248499A (en) * | 1991-10-07 | 1993-09-28 | Genentech, Inc. | Control of microbial infections in transplant patients |
| EP0563487A1 (en) * | 1992-03-31 | 1993-10-06 | Laboratoire Europeen De Biotechnologie S.A. | Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon |
| US5821078A (en) * | 1992-09-03 | 1998-10-13 | Yeda Research And Development Co. Ltd. | Nucleic acid encoding interferon-α/β binding protein |
| US5888511A (en) * | 1993-02-26 | 1999-03-30 | Advanced Biotherapy Concepts, Inc. | Treatment of autoimmune diseases, including AIDS |
| NZ314644A (en) * | 1993-05-24 | 2000-11-24 | Immunex Corp | Use of flt3-ligands as a growth stimulator of stem cells in the transplantation of tissue |
| US5554512A (en) | 1993-05-24 | 1996-09-10 | Immunex Corporation | Ligands for flt3 receptors |
| US6630143B1 (en) * | 1993-05-24 | 2003-10-07 | Immunex Corporation | Antibodies against flt3 ligand |
| CA2171955A1 (en) * | 1993-09-17 | 1995-03-23 | Michael G. Tovey | Pharmaceutical composition comprising monoclonal antibodies against the interferon receptor, with neutralizing activity against type i interferon |
| US5959085A (en) * | 1993-11-23 | 1999-09-28 | Schering Corporation | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
| US5780027A (en) * | 1995-07-14 | 1998-07-14 | Meiogen Biotechnology Corporation | Methods of treatment of down syndrome by interferon antagonists |
| IL118096A0 (en) * | 1996-05-01 | 1996-09-12 | Yeda Res & Dev | Antibodies against interferon alpha/beta receptor |
| US6713609B1 (en) * | 1996-07-16 | 2004-03-30 | Genentech, Inc. | Monoclonal antibodies to type I interferon receptor |
| US5859183A (en) * | 1997-02-13 | 1999-01-12 | The Rockefeller University | Altered telomere repeat binding factor |
| US20030018174A1 (en) * | 1997-10-06 | 2003-01-23 | Genentech, Inc. | Monoclonal antibodies to IFNAR2 |
| ATE428769T1 (de) * | 1997-10-27 | 2009-05-15 | Univ Rockefeller | Methode und zusammensetzung zur herstellung von reifen dendritischen zellen |
| EP1037995A1 (en) * | 1997-12-08 | 2000-09-27 | Genentech, Inc. | Human interferon-epsilon: a type 1 interferon |
| ZA9811070B (en) * | 1997-12-08 | 2000-07-03 | Genentech Inc | Type I interferons. |
| US6291661B1 (en) * | 1998-07-02 | 2001-09-18 | Immunex Corporation | flt3-L mutants and method of use |
| US6673908B1 (en) * | 1999-02-22 | 2004-01-06 | Nuvelo, Inc. | Tumor necrosis factor receptor 2 |
| DE69926920T2 (de) | 1999-12-30 | 2006-06-29 | Imclone Systems, Inc. | Konservierungsfaktoren von Vorläuferzellen und damit verbundene Verfahren und Produkte |
| GB0001710D0 (en) | 2000-01-25 | 2000-03-15 | Pharma Pacific Pty Ltd | Therapeutic treatment |
| US6846486B1 (en) * | 2000-02-24 | 2005-01-25 | Advanced Biotherapy Concepts, Inc. | Method of treating allergy by administering an anti-histamine antibody |
| WO2002024874A2 (en) * | 2000-09-21 | 2002-03-28 | Schering Corporation | Methods for preparing interferon producing dentitric cells |
| BR0206364A (pt) * | 2001-01-09 | 2005-08-16 | Baylor Res Inst | Métodos para tratar doenças auto-imunes em um indivìduo e testes diagnósticos in vitro |
| US7087726B2 (en) * | 2001-02-22 | 2006-08-08 | Genentech, Inc. | Anti-interferon-α antibodies |
| FR2822845B1 (fr) * | 2001-03-30 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides comportant des polymorphismes de type snp fonctionnels dans la sequence nucleotidique du gene ifn-alpha-21 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques |
| US6554512B2 (en) * | 2001-04-26 | 2003-04-29 | Zih Corp. | Printer for printing deformable flat supports and its loader |
| KR100872210B1 (ko) | 2003-04-23 | 2008-12-05 | 메다렉스, 인코포레이티드 | 인터페론 알파 수용체-1 (ifnar-1)에 대한 인체화항체 |
| NZ547157A (en) * | 2003-12-10 | 2009-07-31 | Medarex Inc | Interferon Alpha Antibodies and their uses |
| BRPI0516470A (pt) | 2004-10-07 | 2008-09-09 | Universitot Zuerich | uso de um agente de bloqueio do interferon tipo i, e, método de prevenção e tratamento da psorìase |
-
2002
- 2002-01-08 BR BR0206364-6A patent/BR0206364A/pt not_active Application Discontinuation
- 2002-01-08 WO PCT/US2002/000343 patent/WO2002067760A2/en not_active Ceased
- 2002-01-08 KR KR1020037009204A patent/KR100951409B1/ko not_active Expired - Lifetime
- 2002-01-08 MX MXPA03006100A patent/MXPA03006100A/es active IP Right Grant
- 2002-01-08 CN CN200910160480A patent/CN101612402A/zh active Pending
- 2002-01-08 JP JP2002567137A patent/JP4394350B2/ja not_active Expired - Fee Related
- 2002-01-08 CN CNB028035569A patent/CN100536919C/zh not_active Expired - Lifetime
- 2002-01-08 US US10/466,023 patent/US7544357B2/en not_active Expired - Lifetime
- 2002-01-08 EP EP10163628A patent/EP2236156A3/en not_active Withdrawn
- 2002-01-08 US US10/042,644 patent/US20020160974A1/en not_active Abandoned
- 2002-01-08 DE DE60239522T patent/DE60239522D1/de not_active Expired - Lifetime
- 2002-01-08 AU AU2002246955A patent/AU2002246955B2/en not_active Expired
- 2002-01-08 ES ES02714705T patent/ES2363761T3/es not_active Expired - Lifetime
- 2002-01-08 AT AT02714705T patent/ATE502648T1/de active
- 2002-01-08 EP EP02714705A patent/EP1351707B9/en not_active Revoked
- 2002-01-08 DK DK02714705.7T patent/DK1351707T3/da active
- 2002-01-08 CA CA2433806A patent/CA2433806C/en not_active Expired - Lifetime
-
2009
- 2009-03-16 JP JP2009063336A patent/JP2009132736A/ja not_active Withdrawn
- 2009-05-04 US US12/435,267 patent/US20090263474A1/en not_active Abandoned
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