JP2004519475A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004519475A5 JP2004519475A5 JP2002567137A JP2002567137A JP2004519475A5 JP 2004519475 A5 JP2004519475 A5 JP 2004519475A5 JP 2002567137 A JP2002567137 A JP 2002567137A JP 2002567137 A JP2002567137 A JP 2002567137A JP 2004519475 A5 JP2004519475 A5 JP 2004519475A5
- Authority
- JP
- Japan
- Prior art keywords
- interferon
- pharmaceutical composition
- composition according
- antibody
- antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26054101P | 2001-01-09 | 2001-01-09 | |
| PCT/US2002/000343 WO2002067760A2 (en) | 2001-01-09 | 2002-01-08 | Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009063336A Division JP2009132736A (ja) | 2001-01-09 | 2009-03-16 | 対象における自己免疫疾患の治療法及びinvitro診断アッセイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004519475A JP2004519475A (ja) | 2004-07-02 |
| JP2004519475A5 true JP2004519475A5 (https=) | 2007-05-10 |
| JP4394350B2 JP4394350B2 (ja) | 2010-01-06 |
Family
ID=22989575
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567137A Expired - Fee Related JP4394350B2 (ja) | 2001-01-09 | 2002-01-08 | 対象における自己免疫疾患の治療法及びinvitro診断アッセイ |
| JP2009063336A Withdrawn JP2009132736A (ja) | 2001-01-09 | 2009-03-16 | 対象における自己免疫疾患の治療法及びinvitro診断アッセイ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009063336A Withdrawn JP2009132736A (ja) | 2001-01-09 | 2009-03-16 | 対象における自己免疫疾患の治療法及びinvitro診断アッセイ |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20020160974A1 (https=) |
| EP (2) | EP1351707B9 (https=) |
| JP (2) | JP4394350B2 (https=) |
| KR (1) | KR100951409B1 (https=) |
| CN (2) | CN100536919C (https=) |
| AT (1) | ATE502648T1 (https=) |
| AU (1) | AU2002246955B2 (https=) |
| BR (1) | BR0206364A (https=) |
| CA (1) | CA2433806C (https=) |
| DE (1) | DE60239522D1 (https=) |
| DK (1) | DK1351707T3 (https=) |
| ES (1) | ES2363761T3 (https=) |
| MX (1) | MXPA03006100A (https=) |
| WO (1) | WO2002067760A2 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1351707B9 (en) * | 2001-01-09 | 2012-01-25 | Baylor Research Institute | Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays |
| EP1701736A4 (en) * | 2003-12-24 | 2008-05-07 | Inst Medical W & E Hall | THERAPEUTIC AGENTS AND USES |
| US7662381B2 (en) | 2004-06-21 | 2010-02-16 | Medarex, Inc. | Interferon alpha receptor 1 antibodies and their uses |
| CN103251953A (zh) * | 2004-07-19 | 2013-08-21 | 约翰·霍普金斯大学 | 供免疫抑制的flt3抑制剂 |
| CN101056654A (zh) * | 2004-10-07 | 2007-10-17 | 苏黎士大学 | 用于预防和治疗银屑病的i型干扰素阻断剂 |
| CN101155831B (zh) * | 2005-02-10 | 2015-08-19 | 贝勒研究院 | 抗干扰素α单克隆抗体及其使用方法 |
| US7888481B2 (en) * | 2005-02-10 | 2011-02-15 | Baylor Research Institute | Anti-interferon alpha monoclonal antibodies and methods for use |
| CA2686861A1 (en) * | 2007-05-03 | 2008-11-13 | Medimmune, Llc | Interferon alpha-induced pharmacodynamic markers |
| MX340916B (es) | 2008-01-18 | 2016-07-29 | President And Fellows Of Harvard College * | Metodos para detectar señales de identificacion de enfermedad o condiciones en fluidos corporales. |
| KR20160070165A (ko) | 2008-02-08 | 2016-06-17 | 메디뮨 엘엘씨 | Fc 리간드 친화성이 감소된 항-IFNAR1 항체 |
| CN102083859B (zh) | 2008-05-07 | 2014-09-17 | 阿哥斯医疗公司 | 人源化抗人干扰素-α抗体 |
| EP2353004B1 (en) | 2008-11-12 | 2018-01-03 | Yeda Research and Development Co. Ltd. | Diagnosis of multiple sclerosis |
| CN101812119B (zh) * | 2009-02-25 | 2012-02-01 | 上海荣盛生物药业有限公司 | 与免疫抗体相结合的多肽及其应用 |
| AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
| US20130203624A1 (en) | 2010-07-23 | 2013-08-08 | President And Fellows Of Harvard College | Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions |
| TW201209171A (en) | 2010-07-23 | 2012-03-01 | Harvard College | Methods of detecting diseases or conditions using phagocytic cells |
| CN103384824B (zh) * | 2010-12-06 | 2016-02-03 | Thd股份公司 | 癌症诊断方法及其用途 |
| US9823246B2 (en) | 2011-12-28 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon |
| DE13746292T1 (de) * | 2012-02-10 | 2014-10-30 | Hakushinkouseikai Foundation | Proliferationsmittel für monozyten, kulturmedium zur proliferation von monozyten, verfahren zur herstellung von monozyten, verfahren zur herstellung dendritischer zellen und verfahren zur herstellung eines impfstoffs mit dendritischen zellen |
| WO2014164362A1 (en) | 2013-03-09 | 2014-10-09 | Harry Stylli | Methods of detecting prostate cancer |
| NZ771629A (en) | 2013-03-09 | 2022-12-23 | Harry Stylli | Methods of detecting cancer |
| KR101536697B1 (ko) * | 2013-11-29 | 2015-07-14 | 아주대학교산학협력단 | 베체트병 진단용 조성물 |
| US10626464B2 (en) | 2014-09-11 | 2020-04-21 | Cell Mdx, Llc | Methods of detecting prostate cancer |
| US20160146799A1 (en) | 2014-11-05 | 2016-05-26 | Nirmidas Biotech, Inc. | Metal composites for enhanced imaging |
| CA3029627A1 (en) | 2016-07-01 | 2018-01-04 | Resolve Therapeutics, Llc | Optimized binuclease fusions and methods |
| CA3073537A1 (en) | 2017-08-22 | 2019-02-28 | Sanabio, Llc | Soluble interferon receptors and uses thereof |
| KR20250139415A (ko) * | 2018-02-14 | 2025-09-23 | 호라이즌 테라퓨틱스 아일랜드 디에이씨 | 고양이 맥도너 육종(fms)-유사 티로신 키나제 3 수용체 리간드(flt3l)에 대한 항체 및 자가면역 및 염증 질환을 치료하기 위한 이의 용도 |
| US12123881B2 (en) * | 2018-04-20 | 2024-10-22 | Unm Rainforest Innovations | Rap1-Gtp, Rac1-GTP and FMS-like tyrosine kinase 3 ligand (FLT3-L) as biomarkers for early detection of sepsis |
| WO2019241158A1 (en) * | 2018-06-11 | 2019-12-19 | Univerity Of Washington | Compositions and methods for treating inflammatory diseases |
| CN113238061B (zh) * | 2021-07-09 | 2021-10-01 | 中南大学湘雅医院 | 以cd180阴性b细胞指示重症肌无力病情的试剂盒及应用 |
| CN115032396B (zh) * | 2022-06-29 | 2025-02-21 | 深圳市康尔诺生物技术有限公司 | 一种用于预测或判断受试者的肿瘤免疫治疗效果的生物标志物及其应用 |
| CN115678982A (zh) * | 2022-09-09 | 2023-02-03 | 中山大学 | 一种用于慢性自身免疫病诊断和/或病种判断的试剂盒 |
| AR130792A1 (es) * | 2022-10-20 | 2025-01-22 | Glaxosmithkline Intellectual Property No 3 Ltd | Proteínas de unión a antígeno |
| WO2025015182A2 (en) * | 2023-07-12 | 2025-01-16 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Compositions and methods for treatment of autoimmunity |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423147A (en) * | 1980-04-11 | 1983-12-27 | Secher David S | Monoclonal antibody to interferon-α |
| GR81946B (https=) * | 1980-09-25 | 1984-12-12 | Genentech Inc | |
| US4456748A (en) * | 1981-02-23 | 1984-06-26 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US4414150A (en) * | 1980-11-10 | 1983-11-08 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US4362155A (en) * | 1981-03-24 | 1982-12-07 | Skurkovich Simon V | Method and apparatus for the treatment of autoimmune and allergic diseases |
| US4605394A (en) * | 1982-12-03 | 1986-08-12 | Simon V. Skurkovich | Methods for the treatment of pathological conditions by removing interferon from the organism |
| US4824432A (en) * | 1981-03-24 | 1989-04-25 | S.V.S. Laboratories, Inc. | Method for treating AIDS and other immune deficiencies and immune disorders |
| DE3211263A1 (de) * | 1981-03-31 | 1983-01-27 | Otsuka Pharmaceutical Co. Ltd., Tokyo | Human-interferon verwandte peptide, antigene und antikoerper, sowie verfahren zu deren herstellung |
| US4678751A (en) * | 1981-09-25 | 1987-07-07 | Genentech, Inc. | Hybrid human leukocyte interferons |
| US5582824A (en) * | 1981-10-19 | 1996-12-10 | Genentech, Inc. | Recombinant DES-CYS-TYR-CYS human immune interferon |
| AU561343B2 (en) * | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
| US5096705A (en) * | 1981-10-19 | 1992-03-17 | Genentech, Inc. | Human immune interferon |
| US5827694A (en) * | 1982-03-08 | 1998-10-27 | Genentech, Inc. | DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides |
| US5831023A (en) * | 1982-11-01 | 1998-11-03 | Genentech, Inc. | Recombinant animal interferon polypeptides |
| US4534906A (en) * | 1982-11-01 | 1985-08-13 | Genentech, Inc. | Removal of impurities from human leukocyte interferon preparations |
| EP0139676B1 (en) * | 1983-02-04 | 1992-11-25 | Cytoclonal Pharmaceutics Inc. | Production and characterization of hybridoma antibodies directed specifically against common determinant(s) present among closely related, but distinct proteins |
| GB2148299B (en) * | 1983-09-01 | 1988-01-06 | Hybritech Inc | Antibody compositions of therapeutic agents having an extended serum half-life |
| US4855238A (en) * | 1983-12-16 | 1989-08-08 | Genentech, Inc. | Recombinant gamma interferons having enhanced stability and methods therefor |
| US5082658A (en) * | 1984-01-16 | 1992-01-21 | Genentech, Inc. | Gamma interferon-interleukin-2 synergism |
| FR2560212B1 (fr) * | 1984-02-24 | 1989-12-29 | Unicet | Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps |
| US4650674A (en) * | 1984-07-05 | 1987-03-17 | Genentech, Inc. | Synergistic cytotoxic composition |
| US5196323A (en) * | 1985-04-27 | 1993-03-23 | Boehringer Ingelheim International Gmbh | Process for preparing and purifying alpha-interferon |
| US4828830A (en) * | 1986-01-24 | 1989-05-09 | Genentech, Inc. | Method and composition for prophylaxis and treatment of viral infections |
| JPS6330426A (ja) * | 1986-07-25 | 1988-02-09 | Mitsubishi Chem Ind Ltd | 自己免疫性疾患治療薬 |
| US4851219A (en) * | 1986-11-18 | 1989-07-25 | Genentech, Inc. | Method for the treatment of chronic myelogenous leukemia |
| US4987071A (en) * | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US4944941A (en) * | 1987-08-07 | 1990-07-31 | Genentech, Inc. | Methods and compositions for the treatment of lung conditions |
| US5254678A (en) * | 1987-12-15 | 1993-10-19 | Gene Shears Pty. Limited | Ribozymes |
| AU2844889A (en) | 1988-01-22 | 1989-07-27 | Collagen Corporation | Method for suppressing the growth of normal and cancer cells |
| CA1340323C (en) | 1988-09-20 | 1999-01-19 | Arnold E. Hampel | Rna catalyst for cleaving specific rna sequences |
| US5168053A (en) * | 1989-03-24 | 1992-12-01 | Yale University | Cleavage of targeted RNA by RNAase P |
| US5889151A (en) * | 1989-10-20 | 1999-03-30 | Societe Leb-Tech | Purified human alpha interferon receptor |
| US5919452A (en) * | 1991-03-18 | 1999-07-06 | New York University | Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies |
| ES2133285T3 (es) * | 1991-04-17 | 1999-09-16 | Medisup Int Nv | Polipeptidos hidrosolubles que tienen una alta afinidad para los interferones alfa y beta. |
| US5227158A (en) * | 1991-06-10 | 1993-07-13 | Genentech, Inc. | Method of stimulating hepatocyte proliferation by administration of hepatocyte growth factor and gamma-interferon |
| DK0601052T3 (da) * | 1991-08-30 | 1996-11-18 | Genentech Inc | Terapeutisk fremgangsmåde til behandling af IDDM |
| US5248499A (en) * | 1991-10-07 | 1993-09-28 | Genentech, Inc. | Control of microbial infections in transplant patients |
| EP0563487A1 (en) * | 1992-03-31 | 1993-10-06 | Laboratoire Europeen De Biotechnologie S.A. | Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon |
| US5821078A (en) * | 1992-09-03 | 1998-10-13 | Yeda Research And Development Co. Ltd. | Nucleic acid encoding interferon-α/β binding protein |
| US5888511A (en) * | 1993-02-26 | 1999-03-30 | Advanced Biotherapy Concepts, Inc. | Treatment of autoimmune diseases, including AIDS |
| CZ307995A3 (en) | 1993-05-24 | 1996-10-16 | Immunex Corp | Ligands for flt3 receptors |
| US5554512A (en) | 1993-05-24 | 1996-09-10 | Immunex Corporation | Ligands for flt3 receptors |
| US6630143B1 (en) * | 1993-05-24 | 2003-10-07 | Immunex Corporation | Antibodies against flt3 ligand |
| EP0725654A1 (en) * | 1993-09-17 | 1996-08-14 | Laboratoire Europeen De Biotechnologie S.A. | Pharmaceutical composition comprising monoclonal antibodies against the interferon receptor, with neutralizing activity against type i interferon |
| US5959085A (en) * | 1993-11-23 | 1999-09-28 | Schering Corporation | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
| US5780027A (en) * | 1995-07-14 | 1998-07-14 | Meiogen Biotechnology Corporation | Methods of treatment of down syndrome by interferon antagonists |
| IL118096A0 (en) | 1996-05-01 | 1996-09-12 | Yeda Res & Dev | Antibodies against interferon alpha/beta receptor |
| US6713609B1 (en) * | 1996-07-16 | 2004-03-30 | Genentech, Inc. | Monoclonal antibodies to type I interferon receptor |
| US5859183A (en) * | 1997-02-13 | 1999-01-12 | The Rockefeller University | Altered telomere repeat binding factor |
| US20030018174A1 (en) * | 1997-10-06 | 2003-01-23 | Genentech, Inc. | Monoclonal antibodies to IFNAR2 |
| DE69840739D1 (de) * | 1997-10-27 | 2009-05-28 | Merix Bioscience Inc | Methode und Zusammensetzung zur Herstellung von reifen dendritischen Zellen |
| EP1037995A1 (en) * | 1997-12-08 | 2000-09-27 | Genentech, Inc. | Human interferon-epsilon: a type 1 interferon |
| ZA9811070B (en) * | 1997-12-08 | 2000-07-03 | Genentech Inc | Type I interferons. |
| US6291661B1 (en) * | 1998-07-02 | 2001-09-18 | Immunex Corporation | flt3-L mutants and method of use |
| US6673908B1 (en) * | 1999-02-22 | 2004-01-06 | Nuvelo, Inc. | Tumor necrosis factor receptor 2 |
| AU784361C (en) | 1999-12-30 | 2007-03-15 | Imclone Systems Incorporated | Progenitor cell preservation factors and related methods and products |
| GB0001710D0 (en) * | 2000-01-25 | 2000-03-15 | Pharma Pacific Pty Ltd | Therapeutic treatment |
| US6846486B1 (en) * | 2000-02-24 | 2005-01-25 | Advanced Biotherapy Concepts, Inc. | Method of treating allergy by administering an anti-histamine antibody |
| US6660523B2 (en) * | 2000-09-21 | 2003-12-09 | Schering Corporation | Dendritic cells; methods |
| EP1351707B9 (en) * | 2001-01-09 | 2012-01-25 | Baylor Research Institute | Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays |
| US7087726B2 (en) * | 2001-02-22 | 2006-08-08 | Genentech, Inc. | Anti-interferon-α antibodies |
| FR2822845B1 (fr) * | 2001-03-30 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides comportant des polymorphismes de type snp fonctionnels dans la sequence nucleotidique du gene ifn-alpha-21 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques |
| US6554512B2 (en) * | 2001-04-26 | 2003-04-29 | Zih Corp. | Printer for printing deformable flat supports and its loader |
| JP2007525458A (ja) | 2003-04-23 | 2007-09-06 | メダレックス インコーポレイテッド | インターフェロンα受容体−1(IFNAR−1)に対するヒト化抗体 |
| KR101225299B1 (ko) * | 2003-12-10 | 2013-01-24 | 메다렉스, 인코포레이티드 | 인터페론 알파 항체 및 그의 용도 |
| CN101056654A (zh) | 2004-10-07 | 2007-10-17 | 苏黎士大学 | 用于预防和治疗银屑病的i型干扰素阻断剂 |
-
2002
- 2002-01-08 EP EP02714705A patent/EP1351707B9/en not_active Revoked
- 2002-01-08 CA CA2433806A patent/CA2433806C/en not_active Expired - Lifetime
- 2002-01-08 US US10/042,644 patent/US20020160974A1/en not_active Abandoned
- 2002-01-08 KR KR1020037009204A patent/KR100951409B1/ko not_active Expired - Lifetime
- 2002-01-08 BR BR0206364-6A patent/BR0206364A/pt not_active Application Discontinuation
- 2002-01-08 CN CNB028035569A patent/CN100536919C/zh not_active Expired - Lifetime
- 2002-01-08 MX MXPA03006100A patent/MXPA03006100A/es active IP Right Grant
- 2002-01-08 DK DK02714705.7T patent/DK1351707T3/da active
- 2002-01-08 AT AT02714705T patent/ATE502648T1/de active
- 2002-01-08 WO PCT/US2002/000343 patent/WO2002067760A2/en not_active Ceased
- 2002-01-08 EP EP10163628A patent/EP2236156A3/en not_active Withdrawn
- 2002-01-08 ES ES02714705T patent/ES2363761T3/es not_active Expired - Lifetime
- 2002-01-08 DE DE60239522T patent/DE60239522D1/de not_active Expired - Lifetime
- 2002-01-08 AU AU2002246955A patent/AU2002246955B2/en not_active Expired
- 2002-01-08 CN CN200910160480A patent/CN101612402A/zh active Pending
- 2002-01-08 US US10/466,023 patent/US7544357B2/en not_active Expired - Lifetime
- 2002-01-08 JP JP2002567137A patent/JP4394350B2/ja not_active Expired - Fee Related
-
2009
- 2009-03-16 JP JP2009063336A patent/JP2009132736A/ja not_active Withdrawn
- 2009-05-04 US US12/435,267 patent/US20090263474A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004519475A5 (https=) | ||
| CA2433806A1 (en) | Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays | |
| Saschenbrecker et al. | Serological diagnosis of autoimmune bullous skin diseases | |
| Wadhwa et al. | Strategies for detection, measurement and characterization of unwanted antibodies induced by therapeutic biologicals | |
| Tahara et al. | A sensitive sandwich ELISA for measuring thrombopoietin in human serum: serum thrombopoietin levels in healthy volunteers and in patients with haemopoietic disorders | |
| Corti et al. | Tumor Necrosis Factor (TNF) α quantification by ELISA and bioassay: Effects of TNFα-soluble TNF receptor (p55) complex dissociation during assay incubations | |
| Porta et al. | Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma | |
| Suh et al. | Approaches for the detection and analysis of antidrug antibodies to biopharmaceuticals: A review | |
| JP2013163673A5 (https=) | ||
| CA2434512A1 (en) | Marker for inflammatory conditions | |
| Kasum et al. | Importance of macroprolactinemia in hyperprolactinemia | |
| RU2011118477A (ru) | Способы и композиции для диагностики и лечения аутоиммунной болезни, возникающей вследствие рассеянного склероза | |
| Thorpe et al. | Current methods for detecting antibodies against erythropoietin and other recombinant proteins | |
| Castagna et al. | Hepcidin assay in serum by SELDI-TOF-MS and other approaches | |
| Kakkar et al. | Population PK and IgE pharmacodynamic analysis of a fully human monoclonal antibody against IL4 receptor | |
| Thorpe et al. | Assays for detecting and diagnosing antibody-mediated pure red cell aplasia (PRCA): an assessment of available procedures | |
| Torres et al. | Hypersensitivity reactions to beta-lactams | |
| Meager et al. | Detection of anti-cytokine antibodies and their clinical relevance | |
| Liparoto et al. | Biosensor analysis of the interleukin‐2 receptor complex | |
| WO2003098185A2 (en) | Systems and methods for identifying organ transplant risk | |
| US9927443B2 (en) | Risk assessment for therapeutic drugs | |
| JP2022545312A (ja) | 関節リウマチの診断及び処置の方法 | |
| Groome et al. | Enzyme immunoassays for inhibins, activins and follistatins | |
| US20060003384A1 (en) | Detection of measurement of antibodies to antigenic proteins in biological tissues or samples | |
| Myler et al. | Biotherapeutic bioanalysis: a multi-indication case study review |