JP2004519453A5 - - Google Patents
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- Publication number
- JP2004519453A5 JP2004519453A5 JP2002554134A JP2002554134A JP2004519453A5 JP 2004519453 A5 JP2004519453 A5 JP 2004519453A5 JP 2002554134 A JP2002554134 A JP 2002554134A JP 2002554134 A JP2002554134 A JP 2002554134A JP 2004519453 A5 JP2004519453 A5 JP 2004519453A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- administered
- lipopolysaccharide
- antigens
- immunogenic nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 6
- 102000036639 antigens Human genes 0.000 claims 6
- 108091007433 antigens Proteins 0.000 claims 6
- 239000002158 endotoxin Substances 0.000 claims 5
- 230000002163 immunogen Effects 0.000 claims 5
- 229920006008 lipopolysaccharide Polymers 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 239000013543 active substance Substances 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 1
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 claims 1
- 229930010555 Inosine Natural products 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 108010039918 Polylysine Proteins 0.000 claims 1
- 230000001363 autoimmune Effects 0.000 claims 1
- 244000052616 bacterial pathogen Species 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 229960003786 inosine Drugs 0.000 claims 1
- 244000052769 pathogen Species 0.000 claims 1
- 229920000724 poly(L-arginine) polymer Polymers 0.000 claims 1
- 108010011110 polyarginine Proteins 0.000 claims 1
- 229920000656 polylysine Polymers 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- 244000052613 viral pathogen Species 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2001/000087 WO2001054720A1 (en) | 2000-01-28 | 2001-01-05 | Pharmaceutical composition for immunomodulation and preparation of vaccines comprising an antigen and an immunogenic oligodeoxynucleotide and a polycationic polymer as adjuvants |
| AT6702001 | 2001-04-25 | ||
| PCT/EP2002/000071 WO2002053185A2 (en) | 2001-01-05 | 2002-01-07 | Anti-inflammatory use of polycationic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004519453A JP2004519453A (ja) | 2004-07-02 |
| JP2004519453A5 true JP2004519453A5 (https=) | 2005-12-22 |
Family
ID=25608381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002554134A Pending JP2004519453A (ja) | 2001-01-05 | 2002-01-07 | ポリカチオン性化合物の用途 |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1347776A2 (https=) |
| JP (1) | JP2004519453A (https=) |
| WO (1) | WO2002053185A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004011650A2 (en) | 2002-07-24 | 2004-02-05 | Intercell Ag | Antigens encoded by alternative reading frame from pathogenic viruses |
| WO2004024182A2 (en) | 2002-09-13 | 2004-03-25 | Intercell Ag | Method for isolating hepatitis c virus peptides |
| EP1608402B1 (en) * | 2003-03-24 | 2010-10-20 | Intercell AG | Improved vaccines |
| CN1764473A (zh) * | 2003-03-24 | 2006-04-26 | 英特塞尔股份公司 | 矾与Th1免疫应答诱导佐剂用于增强免疫应答的用途 |
| KR20080034973A (ko) | 2005-07-29 | 2008-04-22 | 산또리 가부시키가이샤 | 후코이단 또는 후코이단 가수분해 생성물과 면역 부활소재를 함유하는 조성물 |
| IN2012DN02345A (https=) | 2009-09-16 | 2015-08-21 | Univ Duke | |
| WO2011101465A1 (en) | 2010-02-19 | 2011-08-25 | Intercell Ag | Ic31 nanoparticles |
| WO2017079537A1 (en) | 2015-11-04 | 2017-05-11 | Duke University | Polycationic polymers for use in treating and detecting cancer |
| US12447464B2 (en) | 2016-12-22 | 2025-10-21 | Duke University | Polycationic microfibers and methods of using the same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1290141A (https=) * | 1968-05-31 | 1972-09-20 | ||
| JPH09176038A (ja) * | 1995-09-18 | 1997-07-08 | Hisamitsu Pharmaceut Co Inc | 抗炎症性アンチセンス薬物 |
| RS50101B (sr) * | 1996-02-24 | 2009-01-22 | Boehringer Ingelheim International Gmbh., | Farmaceutski preparati za imunomodulaciju |
| CA2332127A1 (en) * | 1998-06-26 | 2000-01-06 | N.V. Nutricia | Pharmaceutical preparations for use in combatting or preventing surface infections caused by microorganisms |
| JP2000256196A (ja) * | 1999-03-05 | 2000-09-19 | Pias Arise Kk | 抗炎症，抗アレルギー剤 |
| PT1187629E (pt) * | 1999-04-19 | 2005-02-28 | Glaxosmithkline Biolog Sa | Composicao adjuvante que compreende saponina e um oligonucleotido imunoestimulador |
| JP2001199903A (ja) * | 1999-11-09 | 2001-07-24 | Eizo Mori | 核酸含有複合体 |
| AT410173B (de) * | 2000-06-08 | 2003-02-25 | Cistem Biotechnologies Gmbh | Antigene zusammensetzung |
| RU2413520C2 (ru) * | 2000-06-08 | 2011-03-10 | Интерселл Аг | Вакцинная композиция, содержащая иммуностимулирующие олигодезоксинуклеотиды |
-
2002
- 2002-01-07 JP JP2002554134A patent/JP2004519453A/ja active Pending
- 2002-01-07 EP EP02702238A patent/EP1347776A2/en not_active Withdrawn
- 2002-01-07 WO PCT/EP2002/000071 patent/WO2002053185A2/en not_active Ceased
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