JP2005237328A5 - - Google Patents

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Publication number
JP2005237328A5
JP2005237328A5 JP2004053795A JP2004053795A JP2005237328A5 JP 2005237328 A5 JP2005237328 A5 JP 2005237328A5 JP 2004053795 A JP2004053795 A JP 2004053795A JP 2004053795 A JP2004053795 A JP 2004053795A JP 2005237328 A5 JP2005237328 A5 JP 2005237328A5
Authority
JP
Japan
Prior art keywords
base sequence
immunostimulatory oligonucleotide
immunomodulator
seq
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004053795A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005237328A (ja
JP3976742B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority to JP2004053795A priority Critical patent/JP3976742B2/ja
Priority claimed from JP2004053795A external-priority patent/JP3976742B2/ja
Priority to US10/590,761 priority patent/US7718623B2/en
Priority to PCT/JP2005/003693 priority patent/WO2005083076A1/ja
Publication of JP2005237328A publication Critical patent/JP2005237328A/ja
Publication of JP2005237328A5 publication Critical patent/JP2005237328A5/ja
Application granted granted Critical
Publication of JP3976742B2 publication Critical patent/JP3976742B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2004053795A 2004-02-27 2004-02-27 インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド Expired - Lifetime JP3976742B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2004053795A JP3976742B2 (ja) 2004-02-27 2004-02-27 インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド
US10/590,761 US7718623B2 (en) 2004-02-27 2005-02-25 Immunostimulatory oligonucleotide that induces interferon alpha
PCT/JP2005/003693 WO2005083076A1 (ja) 2004-02-27 2005-02-25 インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004053795A JP3976742B2 (ja) 2004-02-27 2004-02-27 インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド

Publications (3)

Publication Number Publication Date
JP2005237328A JP2005237328A (ja) 2005-09-08
JP2005237328A5 true JP2005237328A5 (https=) 2006-10-12
JP3976742B2 JP3976742B2 (ja) 2007-09-19

Family

ID=34908763

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004053795A Expired - Lifetime JP3976742B2 (ja) 2004-02-27 2004-02-27 インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド

Country Status (3)

Country Link
US (1) US7718623B2 (https=)
JP (1) JP3976742B2 (https=)
WO (1) WO2005083076A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4817599B2 (ja) * 2003-12-25 2011-11-16 独立行政法人科学技術振興機構 免疫活性増強剤とこれを用いた免疫活性の増強方法
CN101460620B (zh) * 2006-05-31 2012-02-15 东丽株式会社 免疫刺激寡核苷酸及其药物用途
JP5280432B2 (ja) * 2007-04-27 2013-09-04 ヒュンジン ヤン 比重の増加した細胞培養用支持体及びその製造方法
WO2009069448A1 (ja) * 2007-11-28 2009-06-04 Toray Industries, Inc. 日本脳炎ワクチン用のアジュバント及び日本脳炎ワクチン
WO2009069447A1 (ja) * 2007-11-28 2009-06-04 Toray Industries, Inc. インフルエンザワクチン用のアジュバント及びインフルエンザワクチン
WO2009069682A1 (ja) * 2007-11-28 2009-06-04 Toray Industries, Inc. 肝炎の治療剤又は予防剤
CN102282155B (zh) 2008-12-02 2017-06-09 日本波涛生命科学公司 磷原子修饰的核酸的合成方法
RU2612521C2 (ru) 2009-07-06 2017-03-09 Онтории, Инк. Новые пролекарства нуклеиновых кислот и способы их применения
JP5868324B2 (ja) 2010-09-24 2016-02-24 株式会社Wave Life Sciences Japan 不斉補助基
GB201021867D0 (en) * 2010-12-23 2011-02-02 Mologen Ag Non-coding immunomodulatory DNA construct
JP5906019B2 (ja) * 2011-03-31 2016-04-20 国立大学法人福井大学 免疫刺激ｇ９．１の抗結核ブースターワクチン創出への応用
CN103796657B (zh) 2011-07-19 2017-07-11 波涛生命科学有限公司 合成官能化核酸的方法
US12268718B2 (en) 2012-01-16 2025-04-08 Labyrinth Holdings Llc Control of cellular redox levels
CA3208225A1 (en) 2012-01-16 2013-07-25 Elizabeth Mckenna Compositions and methods for the treatment of hepatitic diseases and disorders
AR091569A1 (es) 2012-06-28 2015-02-11 Intervet Int Bv Receptores de tipo toll
PL2872485T3 (pl) 2012-07-13 2021-05-31 Wave Life Sciences Ltd. Asymetryczna grupa pomocnicza
KR102213609B1 (ko) 2012-07-13 2021-02-08 웨이브 라이프 사이언시스 리미티드 키랄 제어
CA2879066C (en) * 2012-07-13 2019-08-13 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant
JP2015535829A (ja) 2012-09-21 2015-12-17 マッケーナ、エリザベス 天然に存在するＣｐＧオリゴヌクレオチド組成物およびその治療的適用
JPWO2015108047A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
US10322173B2 (en) 2014-01-15 2019-06-18 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
JPWO2015108048A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
BR112016016400A2 (pt) 2014-01-16 2017-10-03 Wave Life Sciences Ltd Composições de oligonucleotídeos quiralmente controlados, seu uso, sua composição farmacêutica, e métodos
LU92821B1 (en) 2015-09-09 2017-03-20 Mologen Ag Combination comprising immunostimulatory oligonucleotides
GB2542425A (en) 2015-09-21 2017-03-22 Mologen Ag Means for the treatment of HIV
WO2023049275A2 (en) * 2021-09-23 2023-03-30 Arnay Sciences, Llc Cyclic structured oligonucleotides as therapeutic agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0468520A3 (en) * 1990-07-27 1992-07-01 Mitsui Toatsu Chemicals, Inc. Immunostimulatory remedies containing palindromic dna sequences
EP1003850B1 (en) 1997-06-06 2009-05-27 The Regents of the University of California Inhibitors of dna immunostimulatory sequence activity
AU760549B2 (en) 1998-04-03 2003-05-15 University Of Iowa Research Foundation, The Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines
AU783118B2 (en) 1999-09-27 2005-09-29 Coley Pharmaceutical Gmbh Methods related to immunostimulatory nucleic acid-induced interferon
US7585847B2 (en) * 2000-02-03 2009-09-08 Coley Pharmaceutical Group, Inc. Immunostimulatory nucleic acids for the treatment of asthma and allergy
WO2002002172A1 (en) * 2000-06-30 2002-01-10 Univ Jefferson Dna palindrome - oligoguanylic acid compositions and uses thereof
US20030050268A1 (en) * 2001-03-29 2003-03-13 Krieg Arthur M. Immunostimulatory nucleic acid for treatment of non-allergic inflammatory diseases
CA2492823A1 (en) 2001-09-14 2003-03-27 Cytos Biotechnology Ag In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles
DE60234375D1 (de) * 2001-09-14 2009-12-24 Cytos Biotechnology Ag VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
BR0311995A (pt) * 2002-06-20 2005-04-05 Cytos Biotechnology Ag Partìculas semelhantes a vìrus empacotadas para o uso como adjuvantes: método de preparação e uso

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