JP2004518661A - 細菌感染の治療用ピペラジン誘導体 - Google Patents

細菌感染の治療用ピペラジン誘導体 Download PDF

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Publication number
JP2004518661A
JP2004518661A JP2002551557A JP2002551557A JP2004518661A JP 2004518661 A JP2004518661 A JP 2004518661A JP 2002551557 A JP2002551557 A JP 2002551557A JP 2002551557 A JP2002551557 A JP 2002551557A JP 2004518661 A JP2004518661 A JP 2004518661A
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JP
Japan
Prior art keywords
alkyl
alkenyl
hydroxy
substituted
group
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2002551557A
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English (en)
Japanese (ja)
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JP2004518661A5 (https=
Inventor
カトリーヌ・ジュヌヴィエーヴ・イヴェット・ダルトワ
ロジャー・エドワード・マークウェル
マルセル・モルヴァン
ギィ・マルゲリット・マリー・ジェラール・ナドレ
ニール・デイビッド・ピアソン
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SmithKline Beecham Ltd
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SmithKline Beecham Ltd
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Filing date
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Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of JP2004518661A publication Critical patent/JP2004518661A/ja
Publication of JP2004518661A5 publication Critical patent/JP2004518661A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2002551557A 2000-12-20 2001-12-19 細菌感染の治療用ピペラジン誘導体 Pending JP2004518661A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0031088.8A GB0031088D0 (en) 2000-12-20 2000-12-20 Medicaments
PCT/GB2001/005653 WO2002050061A1 (en) 2000-12-20 2001-12-19 Piperazine derivatives for treatment of bacterial infections

Publications (2)

Publication Number Publication Date
JP2004518661A true JP2004518661A (ja) 2004-06-24
JP2004518661A5 JP2004518661A5 (https=) 2005-12-22

Family

ID=9905481

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002551557A Pending JP2004518661A (ja) 2000-12-20 2001-12-19 細菌感染の治療用ピペラジン誘導体

Country Status (9)

Country Link
US (1) US20040077655A1 (https=)
EP (1) EP1343780B1 (https=)
JP (1) JP2004518661A (https=)
AT (1) ATE340171T1 (https=)
AU (1) AU2002222287A1 (https=)
DE (1) DE60123276T2 (https=)
ES (1) ES2269301T3 (https=)
GB (1) GB0031088D0 (https=)
WO (1) WO2002050061A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005502623A (ja) * 2001-07-02 2005-01-27 ノボ　ノルディスク　アクティーゼルスカブ 置換ピペラジンおよびジアゼパン
JP2006312625A (ja) * 2005-04-08 2006-11-16 Toyama Chem Co Ltd ２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体

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GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
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US6632810B2 (en) * 2001-06-29 2003-10-14 Kowa Co., Ltd. Cyclic diamine compound with condensed-ring groups
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WO2003064431A2 (en) * 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
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CN1172919C (zh) * 2002-06-03 2004-10-27 上海医药工业研究院 芳烷醇哌嗪衍生物及其在制备抗抑郁症药物中的应用
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JP2008528598A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
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CN101874032B (zh) 2007-11-26 2013-02-06 富山化学工业株式会社 二氮杂萘衍生物一水合物及其制备方法
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ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
US8673920B2 (en) 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
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US8999990B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
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Cited By (2)

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Publication number Priority date Publication date Assignee Title
JP2005502623A (ja) * 2001-07-02 2005-01-27 ノボ　ノルディスク　アクティーゼルスカブ 置換ピペラジンおよびジアゼパン
JP2006312625A (ja) * 2005-04-08 2006-11-16 Toyama Chem Co Ltd ２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体

Also Published As

Publication number Publication date
EP1343780A1 (en) 2003-09-17
WO2002050061A1 (en) 2002-06-27
GB0031088D0 (en) 2001-01-31
DE60123276T2 (de) 2007-09-27
EP1343780B1 (en) 2006-09-20
AU2002222287A1 (en) 2002-07-01
ATE340171T1 (de) 2006-10-15
WO2002050061A8 (en) 2002-07-25
DE60123276D1 (de) 2006-11-02
ES2269301T3 (es) 2007-04-01
US20040077655A1 (en) 2004-04-22

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