DE60123276D1 - Piperazinderivate zur behandlung bakterieller infektionen - Google Patents

Piperazinderivate zur behandlung bakterieller infektionen

Info

Publication number
DE60123276D1
DE60123276D1 DE60123276T DE60123276T DE60123276D1 DE 60123276 D1 DE60123276 D1 DE 60123276D1 DE 60123276 T DE60123276 T DE 60123276T DE 60123276 T DE60123276 T DE 60123276T DE 60123276 D1 DE60123276 D1 DE 60123276D1
Authority
DE
Germany
Prior art keywords
treatment
bacterial infections
piperazine derivatives
derivatives
piperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60123276T
Other languages
English (en)
Other versions
DE60123276T2 (de
Inventor
Catherine Genevieve Yv Dartois
Roger Edward Markwell
Marcel Morvan
Guy Marguerite Marie Ge Nadler
Neil David Pearson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of DE60123276D1 publication Critical patent/DE60123276D1/de
Application granted granted Critical
Publication of DE60123276T2 publication Critical patent/DE60123276T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60123276T 2000-12-20 2001-12-19 Piperazinderivate zur behandlung bakterieller infektionen Expired - Fee Related DE60123276T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0031088.8A GB0031088D0 (en) 2000-12-20 2000-12-20 Medicaments
GB0031088 2000-12-20
PCT/GB2001/005653 WO2002050061A1 (en) 2000-12-20 2001-12-19 Piperazine derivatives for treatment of bacterial infections

Publications (2)

Publication Number Publication Date
DE60123276D1 true DE60123276D1 (de) 2006-11-02
DE60123276T2 DE60123276T2 (de) 2007-09-27

Family

ID=9905481

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60123276T Expired - Fee Related DE60123276T2 (de) 2000-12-20 2001-12-19 Piperazinderivate zur behandlung bakterieller infektionen

Country Status (9)

Country Link
US (1) US20040077655A1 (de)
EP (1) EP1343780B1 (de)
JP (1) JP2004518661A (de)
AT (1) ATE340171T1 (de)
AU (1) AU2002222287A1 (de)
DE (1) DE60123276T2 (de)
ES (1) ES2269301T3 (de)
GB (1) GB0031088D0 (de)
WO (1) WO2002050061A1 (de)

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WO2007138974A1 (ja) 2006-05-26 2007-12-06 Toyama Chemical Co., Ltd. 新規な複素環化合物またはその塩ならびにその中間体
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WO2014099633A2 (en) 2012-12-19 2014-06-26 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2956142B1 (de) 2013-02-18 2017-09-20 Merck Sharp & Dohme Corp. Inhibitoren des renalen kaliumkanals der äusseren medulla
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Also Published As

Publication number Publication date
JP2004518661A (ja) 2004-06-24
US20040077655A1 (en) 2004-04-22
WO2002050061A1 (en) 2002-06-27
EP1343780A1 (de) 2003-09-17
AU2002222287A1 (en) 2002-07-01
GB0031088D0 (en) 2001-01-31
WO2002050061A8 (en) 2002-07-25
ATE340171T1 (de) 2006-10-15
DE60123276T2 (de) 2007-09-27
EP1343780B1 (de) 2006-09-20
ES2269301T3 (es) 2007-04-01

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: DARTOIS, C.G.Y., BRENTFORD, MIDDLESEX, GB

Inventor name: MARKWELL, ROGER EDWARD, HARLOW, ESSEX, GB

Inventor name: MORVAN, MARCEL, BRENTFORD, MIDDLESEX, GB

Inventor name: NADLER, G.M.G., BRENTFORD, MIDDLESEX, GB

Inventor name: PEARSON, NEIL DAVID, HARLOW, ESSEX, GB

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee