JP2004517898A - Ｓｒｃ族のチエノピリミジン系阻害剤 - Google Patents

Ｓｒｃ族のチエノピリミジン系阻害剤 Download PDF

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Publication number
JP2004517898A
JP2004517898A JP2002557948A JP2002557948A JP2004517898A JP 2004517898 A JP2004517898 A JP 2004517898A JP 2002557948 A JP2002557948 A JP 2002557948A JP 2002557948 A JP2002557948 A JP 2002557948A JP 2004517898 A JP2004517898 A JP 2004517898A
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hydrazone
pyrimidin
methylthieno
phenyl
hydroxy
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Pending
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JP2002557948A
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Japanese (ja)
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JP2004517898A5 (https=
Inventor
ミケル エイ． ベニッシュ，
マイケル ロウレス，
レイモンド ジェイ． エイ． バッド，
Original Assignee
ボード・オブ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム
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Publication of JP2004517898A publication Critical patent/JP2004517898A/ja
Publication of JP2004517898A5 publication Critical patent/JP2004517898A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2002557948A 2000-10-23 2001-10-23 Ｓｒｃ族のチエノピリミジン系阻害剤 Pending JP2004517898A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/694,145 US6503914B1 (en) 2000-10-23 2000-10-23 Thienopyrimidine-based inhibitors of the Src family
PCT/US2001/050198 WO2002057271A2 (en) 2000-10-23 2001-10-23 Thienopyrimidine-based inhibitors of the src family

Publications (2)

Publication Number Publication Date
JP2004517898A true JP2004517898A (ja) 2004-06-17
JP2004517898A5 JP2004517898A5 (https=) 2005-06-02

Family

ID=24787577

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002557948A Pending JP2004517898A (ja) 2000-10-23 2001-10-23 Ｓｒｃ族のチエノピリミジン系阻害剤

Country Status (8)

Country Link
US (3) US6503914B1 (https=)
EP (1) EP1409491A2 (https=)
JP (1) JP2004517898A (https=)
KR (1) KR20030040554A (https=)
AU (1) AU2002246817B2 (https=)
CA (1) CA2426775A1 (https=)
MX (1) MXPA03003580A (https=)
WO (1) WO2002057271A2 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008528502A (ja) * 2005-01-21 2008-07-31 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ タンパク質合成の調節
JP2009518364A (ja) * 2005-12-08 2009-05-07 ラボラトワール セローノ ソシエテ アノニム 増殖を抑えるピリミジル、縮合ピリミジル、ピリジルヒドラゾン
JP2009530401A (ja) * 2006-03-24 2009-08-27 ザ・フェインスタイン・インスティチュート・フォー・メディカル・リサーチ フェノールヒドラゾンマクロファージ転移阻害因子阻害剤
JP2014152148A (ja) * 2013-02-12 2014-08-25 Kumamoto Health Science Univ ポリフェノール化合物
JP2018535980A (ja) * 2015-12-03 2018-12-06 チョーチアン チアンフェン−イエン バイオテクノロジー カンパニー リミテッド チエノ−ピリミジン誘導体およびその使用
JP2019501889A (ja) * 2015-12-03 2019-01-24 シャンハイ イオン ビオテック カンパニー リミテッド 複素環式化合物およびその使用

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008528502A (ja) * 2005-01-21 2008-07-31 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ タンパク質合成の調節
JP2009518364A (ja) * 2005-12-08 2009-05-07 ラボラトワール セローノ ソシエテ アノニム 増殖を抑えるピリミジル、縮合ピリミジル、ピリジルヒドラゾン
JP2009530401A (ja) * 2006-03-24 2009-08-27 ザ・フェインスタイン・インスティチュート・フォー・メディカル・リサーチ フェノールヒドラゾンマクロファージ転移阻害因子阻害剤
JP2014152148A (ja) * 2013-02-12 2014-08-25 Kumamoto Health Science Univ ポリフェノール化合物
JP2018535980A (ja) * 2015-12-03 2018-12-06 チョーチアン チアンフェン−イエン バイオテクノロジー カンパニー リミテッド チエノ−ピリミジン誘導体およびその使用
JP2019501889A (ja) * 2015-12-03 2019-01-24 シャンハイ イオン ビオテック カンパニー リミテッド 複素環式化合物およびその使用

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Publication number Publication date
WO2002057271A2 (en) 2002-07-25
AU2002246817B2 (en) 2007-07-26
CA2426775A1 (en) 2002-07-25
EP1409491A2 (en) 2004-04-21
US20040077663A1 (en) 2004-04-22
US7285556B2 (en) 2007-10-23
MXPA03003580A (es) 2005-04-08
WO2002057271A3 (en) 2003-01-30
USRE39267E1 (en) 2006-09-05
KR20030040554A (ko) 2003-05-22
US6503914B1 (en) 2003-01-07

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