JP2004509914A - 微粒子組成物およびその製造方法 - Google Patents

微粒子組成物およびその製造方法 Download PDF

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Publication number
JP2004509914A
JP2004509914A JP2002530042A JP2002530042A JP2004509914A JP 2004509914 A JP2004509914 A JP 2004509914A JP 2002530042 A JP2002530042 A JP 2002530042A JP 2002530042 A JP2002530042 A JP 2002530042A JP 2004509914 A JP2004509914 A JP 2004509914A
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Prior art keywords
surfactant
polymer
poly
lactide
composition
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JP2002530042A
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Japanese (ja)
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JP2004509914A5 (https=
Inventor
ファン，　ジア−ワ
シン，　マンモハン
オハガン，　デレック
ホラ，　マニンダー
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カイロン　コーポレイション
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Publication of JP2004509914A publication Critical patent/JP2004509914A/ja
Publication of JP2004509914A5 publication Critical patent/JP2004509914A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Biological Depolymerization Polymers (AREA)
JP2002530042A 2000-09-28 2001-09-28 微粒子組成物およびその製造方法 Withdrawn JP2004509914A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23607700P 2000-09-28 2000-09-28
PCT/US2001/030541 WO2002026212A2 (en) 2000-09-28 2001-09-28 Microparticle compositions and methods for the manufacture thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013098678A Division JP2013147514A (ja) 2000-09-28 2013-05-08 微粒子組成物およびその製造方法

Publications (2)

Publication Number Publication Date
JP2004509914A true JP2004509914A (ja) 2004-04-02
JP2004509914A5 JP2004509914A5 (https=) 2012-09-06

Family

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Family Applications (2)

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JP2002530042A Withdrawn JP2004509914A (ja) 2000-09-28 2001-09-28 微粒子組成物およびその製造方法
JP2013098678A Pending JP2013147514A (ja) 2000-09-28 2013-05-08 微粒子組成物およびその製造方法

Family Applications After (1)

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JP2013098678A Pending JP2013147514A (ja) 2000-09-28 2013-05-08 微粒子組成物およびその製造方法

Country Status (14)

Country Link
US (2) US6753015B2 (https=)
EP (1) EP1322292B1 (https=)
JP (2) JP2004509914A (https=)
CN (2) CN1535140A (https=)
AT (1) ATE350015T1 (https=)
AU (2) AU9489801A (https=)
BR (1) BR0114304A (https=)
CA (1) CA2420621C (https=)
DE (1) DE60125795T2 (https=)
ES (1) ES2278786T3 (https=)
MX (1) MXPA03002643A (https=)
RU (1) RU2257198C2 (https=)
WO (1) WO2002026212A2 (https=)
ZA (1) ZA200301743B (https=)

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Publication number Priority date Publication date Assignee Title
JP2006169336A (ja) * 2004-12-15 2006-06-29 Nissan Motor Co Ltd 情報化核酸含有透明樹脂組成物
JP2006169337A (ja) * 2004-12-15 2006-06-29 Nissan Motor Co Ltd 不透明樹脂組成物

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US6977245B2 (en) 1999-04-12 2005-12-20 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
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US8466116B2 (en) 2001-12-20 2013-06-18 The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of CpG oligodeoxynucleotides to induce epithelial cell growth
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006169336A (ja) * 2004-12-15 2006-06-29 Nissan Motor Co Ltd 情報化核酸含有透明樹脂組成物
JP2006169337A (ja) * 2004-12-15 2006-06-29 Nissan Motor Co Ltd 不透明樹脂組成物

Also Published As

Publication number Publication date
AU9489801A (en) 2002-04-08
US7846479B2 (en) 2010-12-07
RU2257198C2 (ru) 2005-07-27
ATE350015T1 (de) 2007-01-15
ES2278786T3 (es) 2007-08-16
CA2420621A1 (en) 2002-04-04
EP1322292A2 (en) 2003-07-02
JP2013147514A (ja) 2013-08-01
DE60125795D1 (de) 2007-02-15
DE60125795T2 (de) 2007-10-18
CN101428006A (zh) 2009-05-13
US6753015B2 (en) 2004-06-22
MXPA03002643A (es) 2003-06-19
CA2420621C (en) 2011-05-24
CN1535140A (zh) 2004-10-06
BR0114304A (pt) 2003-07-29
EP1322292B1 (en) 2007-01-03
US20020136776A1 (en) 2002-09-26
ZA200301743B (en) 2004-10-04
AU2001294898B2 (en) 2006-02-02
WO2002026212A2 (en) 2002-04-04
US20040156913A1 (en) 2004-08-12
WO2002026212A3 (en) 2003-03-27

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