CN1535140A - 微粒体组合物及其生产方法 - Google Patents

微粒体组合物及其生产方法 Download PDF

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Publication number
CN1535140A
CN1535140A CNA018165575A CN01816557A CN1535140A CN 1535140 A CN1535140 A CN 1535140A CN A018165575 A CNA018165575 A CN A018165575A CN 01816557 A CN01816557 A CN 01816557A CN 1535140 A CN1535140 A CN 1535140A
Authority
CN
China
Prior art keywords
detergent
composition
microsomal
lactide
poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA018165575A
Other languages
English (en)
Chinese (zh)
Inventor
J-H
J·-H·方
M·辛格
����ڸ�
D·奥黑根
M·霍拉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NOVARTIS VACCINES and DIAGNOSTIC Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of CN1535140A publication Critical patent/CN1535140A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Biological Depolymerization Polymers (AREA)
CNA018165575A 2000-09-28 2001-09-28 微粒体组合物及其生产方法 Pending CN1535140A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23607700P 2000-09-28 2000-09-28
US60/236,077 2000-09-28

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA2008101750512A Division CN101428006A (zh) 2000-09-28 2001-09-28 微粒体组合物及其生产方法

Publications (1)

Publication Number Publication Date
CN1535140A true CN1535140A (zh) 2004-10-06

Family

ID=22888043

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA018165575A Pending CN1535140A (zh) 2000-09-28 2001-09-28 微粒体组合物及其生产方法
CNA2008101750512A Pending CN101428006A (zh) 2000-09-28 2001-09-28 微粒体组合物及其生产方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2008101750512A Pending CN101428006A (zh) 2000-09-28 2001-09-28 微粒体组合物及其生产方法

Country Status (14)

Country Link
US (2) US6753015B2 (https=)
EP (1) EP1322292B1 (https=)
JP (2) JP2004509914A (https=)
CN (2) CN1535140A (https=)
AT (1) ATE350015T1 (https=)
AU (2) AU9489801A (https=)
BR (1) BR0114304A (https=)
CA (1) CA2420621C (https=)
DE (1) DE60125795T2 (https=)
ES (1) ES2278786T3 (https=)
MX (1) MXPA03002643A (https=)
RU (1) RU2257198C2 (https=)
WO (1) WO2002026212A2 (https=)
ZA (1) ZA200301743B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114617959A (zh) * 2015-09-03 2022-06-14 诺瓦瓦克斯股份有限公司 具有改进的稳定性和免疫原性的疫苗组合物

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Cited By (2)

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CN114617959A (zh) * 2015-09-03 2022-06-14 诺瓦瓦克斯股份有限公司 具有改进的稳定性和免疫原性的疫苗组合物
US12257297B2 (en) 2015-09-03 2025-03-25 Novavax, Inc. Vaccine compositions having improved stability and immunogenicity

Also Published As

Publication number Publication date
AU9489801A (en) 2002-04-08
US7846479B2 (en) 2010-12-07
RU2257198C2 (ru) 2005-07-27
ATE350015T1 (de) 2007-01-15
JP2004509914A (ja) 2004-04-02
ES2278786T3 (es) 2007-08-16
CA2420621A1 (en) 2002-04-04
EP1322292A2 (en) 2003-07-02
JP2013147514A (ja) 2013-08-01
DE60125795D1 (de) 2007-02-15
DE60125795T2 (de) 2007-10-18
CN101428006A (zh) 2009-05-13
US6753015B2 (en) 2004-06-22
MXPA03002643A (es) 2003-06-19
CA2420621C (en) 2011-05-24
BR0114304A (pt) 2003-07-29
EP1322292B1 (en) 2007-01-03
US20020136776A1 (en) 2002-09-26
ZA200301743B (en) 2004-10-04
AU2001294898B2 (en) 2006-02-02
WO2002026212A2 (en) 2002-04-04
US20040156913A1 (en) 2004-08-12
WO2002026212A3 (en) 2003-03-27

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Open date: 20041006