JP2004505036A - 肺気腫の治療のための１３−ｃｉｓ−レチノイン酸の使用 - Google Patents

肺気腫の治療のための１３−ｃｉｓ−レチノイン酸の使用 Download PDF

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Publication number
JP2004505036A
JP2004505036A JP2002515232A JP2002515232A JP2004505036A JP 2004505036 A JP2004505036 A JP 2004505036A JP 2002515232 A JP2002515232 A JP 2002515232A JP 2002515232 A JP2002515232 A JP 2002515232A JP 2004505036 A JP2004505036 A JP 2004505036A
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JP
Japan
Prior art keywords
emphysema
cis
retinoic acid
pharmaceutically acceptable
solvate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002515232A
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English (en)
Japanese (ja)
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JP2004505036A5 (enExample
Inventor
ベローニ，ポーラ・ナネット
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2004505036A publication Critical patent/JP2004505036A/ja
Publication of JP2004505036A5 publication Critical patent/JP2004505036A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002515232A 2000-08-02 2001-07-23 肺気腫の治療のための１３−ｃｉｓ−レチノイン酸の使用 Pending JP2004505036A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/631,151 US6339107B1 (en) 2000-08-02 2000-08-02 Methods for treatment of Emphysema using 13-cis retinoic acid
PCT/EP2001/008484 WO2002009679A2 (en) 2000-08-02 2001-07-23 Use of 13-cis retinoic acid for the treatment of emphysema

Publications (2)

Publication Number Publication Date
JP2004505036A true JP2004505036A (ja) 2004-02-19
JP2004505036A5 JP2004505036A5 (enExample) 2005-03-03

Family

ID=24529991

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002515232A Pending JP2004505036A (ja) 2000-08-02 2001-07-23 肺気腫の治療のための１３−ｃｉｓ−レチノイン酸の使用

Country Status (7)

Country Link
US (2) US6339107B1 (enExample)
EP (1) EP1307187B1 (enExample)
JP (1) JP2004505036A (enExample)
AU (1) AU2001289726A1 (enExample)
DE (1) DE60130661T2 (enExample)
ES (1) ES2292620T3 (enExample)
WO (1) WO2002009679A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006025395A1 (ja) * 2004-08-31 2006-03-09 Yasuhiko Shimizu キャリアフリーの細胞増殖因子を用いた慢性閉塞性肺疾患に対する医薬および処置システム
JP2016504358A (ja) * 2012-12-27 2016-02-12 マイクロドース セラピューテクス，インコーポレイテッド オキシブチニンを投与するための方法および組成物
JPWO2017043616A1 (ja) * 2015-09-10 2018-06-28 国立大学法人 岡山大学 炎症性呼吸器疾患の予防又は治療用医薬組成物

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US6720001B2 (en) * 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
US6339107B1 (en) * 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
CA2440763C (en) * 2001-03-22 2010-05-25 Battelle Memorial Institute Liquid formations for electrohydrodymanic spraying containing polymer and suspended particles
CA2464346A1 (en) * 2001-10-30 2003-05-08 Nektar Therapeutics Al, Corporation Water-soluble polymer conjugates of retinoic acid
US20030185762A1 (en) * 2002-03-22 2003-10-02 Cowan Siu Man L. Highly aqueous liquid carrier formulations
WO2004022042A1 (en) * 2002-09-06 2004-03-18 Oregon Health And Science University Effect of vitamin a gel on paranasal sinus mucosal regeneration
WO2006079209A1 (en) * 2005-01-26 2006-08-03 The University Of British Columbia Pulmonary compositions comprising a vitamin a compound and a surfactant and uses thereof
US20080027031A1 (en) * 2006-03-08 2008-01-31 Kinemed, Inc. Retinoids and Related Compounds for the Treatment of Neuroinflammatory Conditions, Diseases and Disorders
US20070254025A1 (en) * 2006-04-27 2007-11-01 Cronk Peter J Oral contraceptive and acne medication combination and treatment of acne with reduced side effects
US20070254858A1 (en) * 2006-04-27 2007-11-01 Cronk Peter J Contraceptive and Acne Medication Combination and Treatment of Acne and Other Diseases with Reduced Side Effects
BRPI1010972A2 (pt) 2009-05-20 2019-04-16 Ranbaxy Laboratories Limited composição tópica sob a forma de uma solução e método para tratar acne ou outros distúrbios relacionados à pele
US10022348B2 (en) 2009-05-20 2018-07-17 Sun Pharmaceutical Industries Limited Topical solution of isotretinoin
CN102802729A (zh) * 2009-05-20 2012-11-28 兰贝克赛实验室有限公司 异维a酸的液体剂型
CN113372368B (zh) * 2020-03-09 2022-04-12 苏州爱科百发生物医药技术有限公司 一种弹性蛋白酶抑制剂前药及其用途
IL315396A (en) * 2022-03-08 2024-11-01 Mastery Biotech Co Ltd Pharmaceutical composition including retinoic acid and carbohydrate and use thereof
WO2023168607A1 (en) * 2022-03-08 2023-09-14 Mastery Biotech Co., Ltd. Novel retinoic acid compound, pharmaceutical composition including thereof and use thereof

Family Cites Families (20)

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GB334585A (en) * 1929-06-06 1930-09-08 British Glues And Chemicals Lt Improvements in or relating to the separation of solids from liquids
ZA791659B (en) 1978-04-17 1980-04-30 Ici Ltd Process and apparatus for spraying liquid
GB8504253D0 (en) 1985-02-19 1985-03-20 Ici Plc Electrostatic spraying apparatus
IL90069A (en) 1988-04-26 1994-04-12 Us Health The use of 31 cysts of retinoic acid in the preparation of a drug for the treatment of congenital conjunctivitis
DE3815221C2 (de) 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
GB9116909D0 (en) * 1991-08-06 1991-09-18 Salford Ultrafine Chem & Res Morphine derivatives
TW272187B (enExample) 1992-05-20 1996-03-11 Hoffmann La Roche
GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
GB9226717D0 (en) 1992-12-22 1993-02-17 Coffee Ronald A Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories
GB9406255D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9406171D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9410658D0 (en) 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
AU690438B2 (en) 1995-03-14 1998-04-23 Siemens Aktiengesellschaft Ultrasonic atomizer device with removable precision dosating unit
DE69621604T2 (de) 1995-03-14 2002-11-28 Siemens Ag Ultraschall-zerstäuber mit abnehmbarer präzisionsdosiereinheit
US6515022B2 (en) * 1996-04-19 2003-02-04 Sloan-Kettering Institute For Cancer Research Use of inhaled retinoids in the treatment of lung diseases
US6251941B1 (en) 1996-04-19 2001-06-26 Sloan-Kettering Institute For Cancer Research Use of inhaled retinoids in the prevention of cancer
US5998486A (en) 1997-07-08 1999-12-07 Georgetown University School Of Medicine Treatment of emphysema with retinoic acid or other retinoids by inducing formation of gas-exchange units (alveoli)
US5954047A (en) 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
AU750539B2 (en) 1998-03-16 2002-07-18 Novartis Ag Aerosolized active agent delivery
US6339107B1 (en) * 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006025395A1 (ja) * 2004-08-31 2006-03-09 Yasuhiko Shimizu キャリアフリーの細胞増殖因子を用いた慢性閉塞性肺疾患に対する医薬および処置システム
JPWO2006025395A1 (ja) * 2004-08-31 2008-05-08 慶彦 清水 キャリアフリーの細胞増殖因子を用いた慢性閉塞性肺疾患に対する医薬および処置システム
JP2016504358A (ja) * 2012-12-27 2016-02-12 マイクロドース セラピューテクス，インコーポレイテッド オキシブチニンを投与するための方法および組成物
JPWO2017043616A1 (ja) * 2015-09-10 2018-06-28 国立大学法人 岡山大学 炎症性呼吸器疾患の予防又は治療用医薬組成物

Also Published As

Publication number Publication date
WO2002009679A2 (en) 2002-02-07
US20020049252A1 (en) 2002-04-25
DE60130661T2 (de) 2008-07-03
EP1307187A2 (en) 2003-05-07
DE60130661D1 (de) 2007-11-08
AU2001289726A1 (en) 2002-02-13
ES2292620T3 (es) 2008-03-16
US6339107B1 (en) 2002-01-15
EP1307187B1 (en) 2007-09-26
WO2002009679A3 (en) 2002-04-18
US6794416B2 (en) 2004-09-21

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