DE60130661T2 - Verwendung der 13-cis retinsäure zur behandlung von emphysemen - Google Patents
Verwendung der 13-cis retinsäure zur behandlung von emphysemen Download PDFInfo
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- DE60130661T2 DE60130661T2 DE60130661T DE60130661T DE60130661T2 DE 60130661 T2 DE60130661 T2 DE 60130661T2 DE 60130661 T DE60130661 T DE 60130661T DE 60130661 T DE60130661 T DE 60130661T DE 60130661 T2 DE60130661 T2 DE 60130661T2
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- Prior art keywords
- retinoic acid
- cis
- emphysema
- treatment
- hydrate
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
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- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/631,151 US6339107B1 (en) | 2000-08-02 | 2000-08-02 | Methods for treatment of Emphysema using 13-cis retinoic acid |
| US631151 | 2000-08-02 | ||
| PCT/EP2001/008484 WO2002009679A2 (en) | 2000-08-02 | 2001-07-23 | Use of 13-cis retinoic acid for the treatment of emphysema |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60130661D1 DE60130661D1 (de) | 2007-11-08 |
| DE60130661T2 true DE60130661T2 (de) | 2008-07-03 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60130661T Expired - Fee Related DE60130661T2 (de) | 2000-08-02 | 2001-07-23 | Verwendung der 13-cis retinsäure zur behandlung von emphysemen |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6339107B1 (enExample) |
| EP (1) | EP1307187B1 (enExample) |
| JP (1) | JP2004505036A (enExample) |
| AU (1) | AU2001289726A1 (enExample) |
| DE (1) | DE60130661T2 (enExample) |
| ES (1) | ES2292620T3 (enExample) |
| WO (1) | WO2002009679A2 (enExample) |
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| US6720001B2 (en) * | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
| US6339107B1 (en) * | 2000-08-02 | 2002-01-15 | Syntex (U.S.A.) Llc | Methods for treatment of Emphysema using 13-cis retinoic acid |
| EP1370238B1 (en) * | 2001-03-22 | 2008-11-12 | Battelle Memorial Institute | Liquid formulations for electrohydrodynamic spraying containing polymer and suspended particles |
| ES2284959T3 (es) * | 2001-10-30 | 2007-11-16 | Nektar Therapeutics Al, Corporation | Conjugados polimericos solubles en agua de acido retinoico. |
| US20030185762A1 (en) * | 2002-03-22 | 2003-10-02 | Cowan Siu Man L. | Highly aqueous liquid carrier formulations |
| US20040122110A1 (en) * | 2002-09-06 | 2004-06-24 | Maccabee Mendy S. | Effect of vitamin A gel on paranasal sinus mucosal regeneration |
| WO2006025395A1 (ja) * | 2004-08-31 | 2006-03-09 | Yasuhiko Shimizu | キャリアフリーの細胞増殖因子を用いた慢性閉塞性肺疾患に対する医薬および処置システム |
| WO2006079209A1 (en) * | 2005-01-26 | 2006-08-03 | The University Of British Columbia | Pulmonary compositions comprising a vitamin a compound and a surfactant and uses thereof |
| US20080027031A1 (en) * | 2006-03-08 | 2008-01-31 | Kinemed, Inc. | Retinoids and Related Compounds for the Treatment of Neuroinflammatory Conditions, Diseases and Disorders |
| US20070254858A1 (en) * | 2006-04-27 | 2007-11-01 | Cronk Peter J | Contraceptive and Acne Medication Combination and Treatment of Acne and Other Diseases with Reduced Side Effects |
| US20070254025A1 (en) * | 2006-04-27 | 2007-11-01 | Cronk Peter J | Oral contraceptive and acne medication combination and treatment of acne with reduced side effects |
| US20120259013A1 (en) * | 2009-05-20 | 2012-10-11 | Ranbaxy Laboratories Limited | Liquid dosage forms of isotretinoin |
| WO2010134048A2 (en) | 2009-05-20 | 2010-11-25 | Ranbaxy Laboratories Limited | Topical retinoid solutions |
| US10022348B2 (en) | 2009-05-20 | 2018-07-17 | Sun Pharmaceutical Industries Limited | Topical solution of isotretinoin |
| EA201591218A1 (ru) * | 2012-12-27 | 2015-11-30 | Майкродоуз Терапьютикс, Инк. | Способы и композиции для введения оксибутинина |
| US11026932B2 (en) | 2015-09-10 | 2021-06-08 | National University Corporation Okayama University | Medicinal composition for preventing or treating inflammatory respiratory disease |
| CN113372368B (zh) | 2020-03-09 | 2022-04-12 | 苏州爱科百发生物医药技术有限公司 | 一种弹性蛋白酶抑制剂前药及其用途 |
| IL315396A (en) * | 2022-03-08 | 2024-11-01 | Mastery Biotech Co Ltd | Pharmaceutical composition including retinoic acid and carbohydrate and use thereof |
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| GB334585A (en) * | 1929-06-06 | 1930-09-08 | British Glues And Chemicals Lt | Improvements in or relating to the separation of solids from liquids |
| ZA791659B (en) | 1978-04-17 | 1980-04-30 | Ici Ltd | Process and apparatus for spraying liquid |
| GB8504253D0 (en) | 1985-02-19 | 1985-03-20 | Ici Plc | Electrostatic spraying apparatus |
| IL90069A (en) | 1988-04-26 | 1994-04-12 | Us Health | The use of 31 cysts of retinoic acid in the preparation of a drug for the treatment of congenital conjunctivitis |
| DE3815221C2 (de) | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
| GB9116909D0 (en) * | 1991-08-06 | 1991-09-18 | Salford Ultrafine Chem & Res | Morphine derivatives |
| TW272187B (enExample) | 1992-05-20 | 1996-03-11 | Hoffmann La Roche | |
| GB9225098D0 (en) | 1992-12-01 | 1993-01-20 | Coffee Ronald A | Charged droplet spray mixer |
| GB9226717D0 (en) | 1992-12-22 | 1993-02-17 | Coffee Ronald A | Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories |
| GB9406255D0 (en) | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
| GB9406171D0 (en) | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
| GB9410658D0 (en) | 1994-05-27 | 1994-07-13 | Electrosols Ltd | Dispensing device |
| ES2177771T3 (es) | 1995-03-14 | 2002-12-16 | Siemens Ag | Dispositivo atomizador ultrasonico con unidad desmontable de dosificacion de precision. |
| ZA962077B (en) | 1995-03-14 | 1997-03-26 | Siemens Ag | Ultrasonic atomizer device with removable precision dosating unit |
| US6515022B2 (en) * | 1996-04-19 | 2003-02-04 | Sloan-Kettering Institute For Cancer Research | Use of inhaled retinoids in the treatment of lung diseases |
| US6251941B1 (en) | 1996-04-19 | 2001-06-26 | Sloan-Kettering Institute For Cancer Research | Use of inhaled retinoids in the prevention of cancer |
| US5998486A (en) | 1997-07-08 | 1999-12-07 | Georgetown University School Of Medicine | Treatment of emphysema with retinoic acid or other retinoids by inducing formation of gas-exchange units (alveoli) |
| NZ504021A (en) | 1997-10-17 | 2003-04-29 | Systemic Pulmonary Delivery Lt | Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication |
| EP1066074A1 (en) | 1998-03-16 | 2001-01-10 | Inhale Therapeutic Systems, Inc. | Aerosolized active agent delivery |
| US6339107B1 (en) * | 2000-08-02 | 2002-01-15 | Syntex (U.S.A.) Llc | Methods for treatment of Emphysema using 13-cis retinoic acid |
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| EP1307187B1 (en) | 2007-09-26 |
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| US6339107B1 (en) | 2002-01-15 |
| US6794416B2 (en) | 2004-09-21 |
| EP1307187A2 (en) | 2003-05-07 |
| US20020049252A1 (en) | 2002-04-25 |
| WO2002009679A2 (en) | 2002-02-07 |
| JP2004505036A (ja) | 2004-02-19 |
| WO2002009679A3 (en) | 2002-04-18 |
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