JP2004502446A5 - - Google Patents

Info

Publication number

JP2004502446A5

JP2004502446A5 JP2002509358A JP2002509358A JP2004502446A5 JP 2004502446 A5 JP2004502446 A5 JP 2004502446A5 JP 2002509358 A JP2002509358 A JP 2002509358A JP 2002509358 A JP2002509358 A JP 2002509358A JP 2004502446 A5 JP2004502446 A5 JP 2004502446A5

Authority

JP

Japan

Prior art keywords

polypeptide

polynucleotide

seq

amino acid

nos

Prior art date

2001-07-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

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• 229920001184 polypeptide Polymers 0.000 description 16
• 102000004196 processed proteins & peptides Human genes 0.000 description 16
• 108090000765 processed proteins & peptides Proteins 0.000 description 16
• 239000002157 polynucleotide Substances 0.000 description 12
• 102000040430 polynucleotide Human genes 0.000 description 11
• 108091033319 polynucleotide Proteins 0.000 description 11
• 229960005486 vaccine Drugs 0.000 description 6
• 125000003275 alpha amino acid group Chemical group 0.000 description 4
• 238000000034 method Methods 0.000 description 4
• 230000001225 therapeutic effect Effects 0.000 description 4
• 239000002253 acid Substances 0.000 description 3
• -1 amino Chemical group 0.000 description 3
• 239000002773 nucleotide Substances 0.000 description 3
• 125000003729 nucleotide group Chemical group 0.000 description 3
• 238000011321 prophylaxis Methods 0.000 description 3
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 2
• 150000001413 amino acids Chemical class 0.000 description 2
• 230000028993 immune response Effects 0.000 description 2
• 230000001939 inductive effect Effects 0.000 description 2
• 208000031729 Bacteremia Diseases 0.000 description 1
• 201000000297 Erysipelas Diseases 0.000 description 1
• 206010016228 Fasciitis Diseases 0.000 description 1
• 206010021531 Impetigo Diseases 0.000 description 1
• 201000007100 Pharyngitis Diseases 0.000 description 1
• 206010039587 Scarlet Fever Diseases 0.000 description 1
• 206010040070 Septic Shock Diseases 0.000 description 1
• 206010044248 Toxic shock syndrome Diseases 0.000 description 1
• 231100000650 Toxic shock syndrome Toxicity 0.000 description 1
• 239000002671 adjuvant Substances 0.000 description 1
• 230000000295 complement effect Effects 0.000 description 1
• 239000003085 diluting agent Substances 0.000 description 1
• 239000003814 drug Substances 0.000 description 1
• 239000003937 drug carrier Substances 0.000 description 1
• 208000015181 infectious disease Diseases 0.000 description 1
• 238000004519 manufacturing process Methods 0.000 description 1
• 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 description 1
• 230000000069 prophylactic effect Effects 0.000 description 1
• 230000003248 secreting effect Effects 0.000 description 1