CA2413576C - Streptococcus pyogenes antigens - Google Patents

Info

Publication number

CA2413576C

CA2413576C CA2413576A CA2413576A CA2413576C CA 2413576 C CA2413576 C CA 2413576C CA 2413576 A CA2413576 A CA 2413576A CA 2413576 A CA2413576 A CA 2413576A CA 2413576 C CA2413576 C CA 2413576C

Authority

CA

Canada

Prior art keywords

ala

ser

thr

pro

val

Prior art date

2000-07-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired - Fee Related

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• 239000000427 antigen Substances 0.000 title abstract description 19
• 108091007433 antigens Proteins 0.000 title abstract description 19
• 102000036639 antigens Human genes 0.000 title abstract description 19
• 102000004196 processed proteins & peptides Human genes 0.000 claims description 117
• 108090000765 processed proteins & peptides Proteins 0.000 claims description 117
• 229920001184 polypeptide Polymers 0.000 claims description 115
• 108091033319 polynucleotide Proteins 0.000 claims description 43
• 102000040430 polynucleotide Human genes 0.000 claims description 43
• 239000002157 polynucleotide Substances 0.000 claims description 43
• 125000003275 alpha amino acid group Chemical group 0.000 claims description 28
• 208000015181 infectious disease Diseases 0.000 claims description 23
• 239000013598 vector Substances 0.000 claims description 18
• 238000000034 method Methods 0.000 claims description 16
• 239000000203 mixture Substances 0.000 claims description 15
• 229960005486 vaccine Drugs 0.000 claims description 15
• 239000002773 nucleotide Substances 0.000 claims description 11
• 125000003729 nucleotide group Chemical group 0.000 claims description 11
• 239000002671 adjuvant Substances 0.000 claims description 9
• 238000011282 treatment Methods 0.000 claims description 7
• 241000282414 Homo sapiens Species 0.000 claims description 6
• 230000000295 complement effect Effects 0.000 claims description 6
• 238000004519 manufacturing process Methods 0.000 claims description 6
• 206010040070 Septic Shock Diseases 0.000 claims description 4
• 206010044248 Toxic shock syndrome Diseases 0.000 claims description 4
• 231100000650 Toxic shock syndrome Toxicity 0.000 claims description 4
• 230000028993 immune response Effects 0.000 claims description 4
• 230000008569 process Effects 0.000 claims description 4
• 208000031729 Bacteremia Diseases 0.000 claims description 3
• 201000000297 Erysipelas Diseases 0.000 claims description 3
• 206010021531 Impetigo Diseases 0.000 claims description 3
• 206010028885 Necrotising fasciitis Diseases 0.000 claims description 3
• 201000007100 Pharyngitis Diseases 0.000 claims description 3
• 206010039587 Scarlet Fever Diseases 0.000 claims description 3
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• 230000003248 secreting effect Effects 0.000 claims description 3
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