JP2004131495A5 - - Google Patents
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- Publication number
- JP2004131495A5 JP2004131495A5 JP2003323310A JP2003323310A JP2004131495A5 JP 2004131495 A5 JP2004131495 A5 JP 2004131495A5 JP 2003323310 A JP2003323310 A JP 2003323310A JP 2003323310 A JP2003323310 A JP 2003323310A JP 2004131495 A5 JP2004131495 A5 JP 2004131495A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- group
- substituted
- composition according
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- 125000004432 carbon atom Chemical group C* 0.000 claims 10
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 10
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 10
- -1 polyoxyethylene group Polymers 0.000 claims 10
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- 150000001412 amines Chemical class 0.000 claims 6
- 150000001408 amides Chemical class 0.000 claims 5
- 239000003961 penetration enhancing agent Substances 0.000 claims 5
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 4
- 235000014113 dietary fatty acids Nutrition 0.000 claims 4
- 229930195729 fatty acid Natural products 0.000 claims 4
- 239000000194 fatty acid Substances 0.000 claims 4
- 150000004665 fatty acids Chemical class 0.000 claims 3
- 230000000699 topical effect Effects 0.000 claims 3
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 claims 2
- ZRVUJXDFFKFLMG-UHFFFAOYSA-N Meloxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=NC=C(C)S1 ZRVUJXDFFKFLMG-UHFFFAOYSA-N 0.000 claims 2
- 208000002193 Pain Diseases 0.000 claims 2
- 102100038280 Prostaglandin G/H synthase 2 Human genes 0.000 claims 2
- 108050003267 Prostaglandin G/H synthase 2 Proteins 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000002532 enzyme inhibitor Substances 0.000 claims 2
- 239000003349 gelling agent Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229960001929 meloxicam Drugs 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 235000007586 terpenes Nutrition 0.000 claims 2
- 239000002562 thickening agent Substances 0.000 claims 2
- 230000037317 transdermal delivery Effects 0.000 claims 2
- QGLWBTPVKHMVHM-KTKRTIGZSA-N (z)-octadec-9-en-1-amine Chemical compound CCCCCCCC\C=C/CCCCCCCCN QGLWBTPVKHMVHM-KTKRTIGZSA-N 0.000 claims 1
- KQIXMZWXFFHRAQ-UHFFFAOYSA-N 1-(2-hydroxybutylamino)butan-2-ol Chemical compound CCC(O)CNCC(O)CC KQIXMZWXFFHRAQ-UHFFFAOYSA-N 0.000 claims 1
- BFIAIMMAHAIVFT-UHFFFAOYSA-N 1-[bis(2-hydroxybutyl)amino]butan-2-ol Chemical compound CCC(O)CN(CC(O)CC)CC(O)CC BFIAIMMAHAIVFT-UHFFFAOYSA-N 0.000 claims 1
- BLFRQYKZFKYQLO-UHFFFAOYSA-N 4-aminobutan-1-ol Chemical compound NCCCCO BLFRQYKZFKYQLO-UHFFFAOYSA-N 0.000 claims 1
- 208000008035 Back Pain Diseases 0.000 claims 1
- 235000013162 Cocos nucifera Nutrition 0.000 claims 1
- 244000060011 Cocos nucifera Species 0.000 claims 1
- 201000011275 Epicondylitis Diseases 0.000 claims 1
- 208000008930 Low Back Pain Diseases 0.000 claims 1
- 208000000112 Myalgia Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010034464 Periarthritis Diseases 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 1
- WUGQZFFCHPXWKQ-UHFFFAOYSA-N Propanolamine Chemical compound NCCCO WUGQZFFCHPXWKQ-UHFFFAOYSA-N 0.000 claims 1
- 208000002240 Tennis Elbow Diseases 0.000 claims 1
- 208000004760 Tenosynovitis Diseases 0.000 claims 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims 1
- SLINHMUFWFWBMU-UHFFFAOYSA-N Triisopropanolamine Chemical compound CC(O)CN(CC(C)O)CC(C)O SLINHMUFWFWBMU-UHFFFAOYSA-N 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 125000006165 cyclic alkyl group Chemical group 0.000 claims 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 claims 1
- LVTYICIALWPMFW-UHFFFAOYSA-N diisopropanolamine Chemical compound CC(O)CNCC(C)O LVTYICIALWPMFW-UHFFFAOYSA-N 0.000 claims 1
- 229940043276 diisopropanolamine Drugs 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 229940125532 enzyme inhibitor Drugs 0.000 claims 1
- 235000019441 ethanol Nutrition 0.000 claims 1
- 150000002191 fatty alcohols Chemical class 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- OXROWJKCGCOJDO-JLHYYAGUSA-N lornoxicam Chemical compound O=C1C=2SC(Cl)=CC=2S(=O)(=O)N(C)\C1=C(\O)NC1=CC=CC=N1 OXROWJKCGCOJDO-JLHYYAGUSA-N 0.000 claims 1
- 229960002202 lornoxicam Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 206010034674 peritonitis Diseases 0.000 claims 1
- 229960002702 piroxicam Drugs 0.000 claims 1
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 231100000245 skin permeability Toxicity 0.000 claims 1
- 230000003637 steroidlike Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 229960002871 tenoxicam Drugs 0.000 claims 1
- WZWYJBNHTWCXIM-UHFFFAOYSA-N tenoxicam Chemical compound O=C1C=2SC=CC=2S(=O)(=O)N(C)C1=C(O)NC1=CC=CC=N1 WZWYJBNHTWCXIM-UHFFFAOYSA-N 0.000 claims 1
- 150000003505 terpenes Chemical class 0.000 claims 1
- 230000000472 traumatic effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003323310A JP2004131495A (ja) | 2002-09-17 | 2003-09-16 | 非ステロイド系抗炎症剤の局所送達用医薬組成物 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002309012 | 2002-09-17 | ||
| JP2003323310A JP2004131495A (ja) | 2002-09-17 | 2003-09-16 | 非ステロイド系抗炎症剤の局所送達用医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004131495A JP2004131495A (ja) | 2004-04-30 |
| JP2004131495A5 true JP2004131495A5 (enExample) | 2006-10-26 |
Family
ID=32301814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003323310A Pending JP2004131495A (ja) | 2002-09-17 | 2003-09-16 | 非ステロイド系抗炎症剤の局所送達用医薬組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2004131495A (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005123046A1 (en) * | 2004-06-15 | 2005-12-29 | Amorepacific Corporation | Novel transdermal preparation and its producing method |
| PL1824493T3 (pl) * | 2004-12-06 | 2009-01-30 | Janssen Pharmaceutica Nv | Zawiesina zawierająca meloksykam do podawania doustnego |
| KR100835074B1 (ko) * | 2006-09-27 | 2008-06-03 | 조선대학교산학협력단 | 멜록시캄 경피 흡수제 조성물 및 그의 제조 방법 |
| JP2009280509A (ja) * | 2008-05-20 | 2009-12-03 | Kowa Co | 鎮痛・抗炎症剤含有外用剤 |
| JP5622410B2 (ja) * | 2010-03-12 | 2014-11-12 | 帝國製薬株式会社 | ケトプロフェン含有水性貼付剤 |
| JP5723843B2 (ja) * | 2012-09-26 | 2015-05-27 | 三洋化成工業株式会社 | 脂肪族アミンアルキレンオキサイド付加物含有組成物 |
| CN122182527A (zh) | 2016-05-05 | 2026-06-12 | 阿奎斯蒂弗医疗股份有限公司 | 增强递送的肾上腺素组合物 |
| JP7431724B2 (ja) * | 2017-09-27 | 2024-02-15 | アクエスティブ セラピューティクス インコーポレイテッド | 増強された透過を有する医薬組成物 |
| WO2023076281A1 (en) | 2021-10-25 | 2023-05-04 | Aquestive Therapeutics, Inc. | Oral and nasal compositions and methods of treatment |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0753671B2 (ja) * | 1985-12-26 | 1995-06-07 | 積水化学工業株式会社 | 経皮・経粘膜製剤 |
| JPH0755911B2 (ja) * | 1987-02-26 | 1995-06-14 | 株式会社資生堂 | 経皮吸収促進剤及びこれを含有する皮膚外用製剤 |
| JP2507158B2 (ja) * | 1990-08-23 | 1996-06-12 | 積水化学工業株式会社 | 経皮吸収製剤 |
| JPH085806B2 (ja) * | 1990-11-29 | 1996-01-24 | 積水化学工業株式会社 | 経皮吸収製剤 |
| JPH0624965A (ja) * | 1992-01-14 | 1994-02-01 | Hisamitsu Pharmaceut Co Inc | テニダップ含有シップ剤 |
| JPH07118145A (ja) * | 1993-10-25 | 1995-05-09 | Suntory Ltd | 皮膚損傷治療用外用剤 |
| JP2936408B2 (ja) * | 1997-03-27 | 1999-08-23 | 富山化学工業株式会社 | オキシカム系抗炎症剤の外用剤 |
| KR20010023256A (ko) * | 1997-08-27 | 2001-03-26 | 헥살 아게 | 용해도와 생체 이용성이 개선된 신규의 멜록시캄 의약조성물 |
| JP2000143540A (ja) * | 1998-11-06 | 2000-05-23 | Bristol Myers Squibb Co | 非ステロイド系消炎鎮痛薬含有外用剤 |
-
2003
- 2003-09-16 JP JP2003323310A patent/JP2004131495A/ja active Pending
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