JP2003529593A5 - - Google Patents
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- Publication number
- JP2003529593A5 JP2003529593A5 JP2001572483A JP2001572483A JP2003529593A5 JP 2003529593 A5 JP2003529593 A5 JP 2003529593A5 JP 2001572483 A JP2001572483 A JP 2001572483A JP 2001572483 A JP2001572483 A JP 2001572483A JP 2003529593 A5 JP2003529593 A5 JP 2003529593A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxymutilin
- ester
- carbamic acid
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC(CC([C@](C[C@@](*=O)O)*1)C(C)[C@]([C@](C)(*)C2)O)[C@@]1(C)[C@@]2OCNC(*)=O Chemical compound CC(CC([C@](C[C@@](*=O)O)*1)C(C)[C@]([C@](C)(*)C2)O)[C@@]1(C)[C@@]2OCNC(*)=O 0.000 description 9
- UDMSAJCHCPRAST-ISTVENEXSA-N CC(/C=N\C(\C)=C/N)N Chemical compound CC(/C=N\C(\C)=C/N)N UDMSAJCHCPRAST-ISTVENEXSA-N 0.000 description 1
- YKGUXRUBAFSWAN-QVXLNCAUSA-N CC(C)/C=C(\C=C/N)/N Chemical compound CC(C)/C=C(\C=C/N)/N YKGUXRUBAFSWAN-QVXLNCAUSA-N 0.000 description 1
- BOFGYEXXHNKKLA-UHFFFAOYSA-N CC1=CC=CNC1 Chemical compound CC1=CC=CNC1 BOFGYEXXHNKKLA-UHFFFAOYSA-N 0.000 description 1
- MHUGUFYRWAUTBP-UHFFFAOYSA-N Cc(cn1)cc(N)c1OC Chemical compound Cc(cn1)cc(N)c1OC MHUGUFYRWAUTBP-UHFFFAOYSA-N 0.000 description 1
- IWHCRXIOIHHNHX-UHFFFAOYSA-N Cc1c2nccc[n]2nc1 Chemical compound Cc1c2nccc[n]2nc1 IWHCRXIOIHHNHX-UHFFFAOYSA-N 0.000 description 1
- LKYQLOSMAQQSRZ-UHFFFAOYSA-N Cc1c[s]c(C2CCNCC2)n1 Chemical compound Cc1c[s]c(C2CCNCC2)n1 LKYQLOSMAQQSRZ-UHFFFAOYSA-N 0.000 description 1
- QVFHSGHXKXLQGN-UHFFFAOYSA-N Cc1cc(CC=C)c(N=C)nc1 Chemical compound Cc1cc(CC=C)c(N=C)nc1 QVFHSGHXKXLQGN-UHFFFAOYSA-N 0.000 description 1
- DBZRHTFNKRSZTF-UHFFFAOYSA-N Cc1ccnc(C=N)c1 Chemical compound Cc1ccnc(C=N)c1 DBZRHTFNKRSZTF-UHFFFAOYSA-N 0.000 description 1
- GUABFMPMKJGSBQ-UHFFFAOYSA-N Cc1cnc(N)[s]1 Chemical compound Cc1cnc(N)[s]1 GUABFMPMKJGSBQ-UHFFFAOYSA-N 0.000 description 1
- MHZNCOBCMWBPPM-UHFFFAOYSA-N Cc1cnc(N)nc1 Chemical compound Cc1cnc(N)nc1 MHZNCOBCMWBPPM-UHFFFAOYSA-N 0.000 description 1
- TWGNOYAGHYUFFR-UHFFFAOYSA-N Cc1cncnc1 Chemical compound Cc1cncnc1 TWGNOYAGHYUFFR-UHFFFAOYSA-N 0.000 description 1
- NWAGBIGYWRXBAI-UHFFFAOYSA-N Nc1nc(I)c[s]1 Chemical compound Nc1nc(I)c[s]1 NWAGBIGYWRXBAI-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0008260.2 | 2000-04-04 | ||
| GBGB0008260.2A GB0008260D0 (en) | 2000-04-04 | 2000-04-04 | Novel compounds |
| GB0027182.5 | 2000-11-04 | ||
| GB0027182A GB0027182D0 (en) | 2000-11-04 | 2000-11-04 | Novel comounds |
| PCT/EP2001/003594 WO2001074788A1 (en) | 2000-04-04 | 2001-03-29 | 2-hydroxy-mutilin carbamate derivatives for antibacterial use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003529593A JP2003529593A (ja) | 2003-10-07 |
| JP2003529593A5 true JP2003529593A5 (enExample) | 2008-05-15 |
Family
ID=26244040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001572483A Pending JP2003529593A (ja) | 2000-04-04 | 2001-03-29 | 抗菌剤として用いるための２−ヒドロキシムチリンカルバメート誘導体 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6972297B2 (enExample) |
| EP (1) | EP1268443B1 (enExample) |
| JP (1) | JP2003529593A (enExample) |
| KR (1) | KR100758441B1 (enExample) |
| CN (1) | CN1210267C (enExample) |
| AR (1) | AR030203A1 (enExample) |
| AT (1) | ATE437860T1 (enExample) |
| AU (2) | AU6382701A (enExample) |
| BR (1) | BR0109809A (enExample) |
| CA (1) | CA2405132A1 (enExample) |
| CO (1) | CO5280223A1 (enExample) |
| CZ (1) | CZ20023290A3 (enExample) |
| DE (1) | DE60139382D1 (enExample) |
| ES (1) | ES2328109T3 (enExample) |
| HU (1) | HUP0300370A3 (enExample) |
| IL (1) | IL151887A0 (enExample) |
| MX (1) | MXPA02009816A (enExample) |
| NO (1) | NO324229B1 (enExample) |
| NZ (1) | NZ521536A (enExample) |
| PL (1) | PL358666A1 (enExample) |
| WO (1) | WO2001074788A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0024811D0 (en) | 2000-10-10 | 2000-11-22 | Smithkline Beecham Plc | Novel compounds |
| US7176310B1 (en) | 2002-04-09 | 2007-02-13 | Ucb Sa | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents |
| GB0209262D0 (en) * | 2002-04-23 | 2002-06-05 | Biochemie Gmbh | Organic compounds |
| DE60317208T2 (de) * | 2002-07-24 | 2008-08-07 | Nabriva Therapeutics Forschungs Gmbh | Pleuromutilinderivate als antimikrobielle mittel |
| GB0218578D0 (en) * | 2002-08-09 | 2002-09-18 | Glaxo Group Ltd | Novel method |
| GB0308114D0 (en) * | 2003-04-08 | 2003-05-14 | Glaxo Group Ltd | Novel compounds |
| FR2856685B1 (fr) * | 2003-06-25 | 2005-09-23 | Merck Sante Sas | Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| US20090291987A1 (en) * | 2004-12-13 | 2009-11-26 | Glaxo Group Limited | Novel polymorph of (5-amino-6-methoxy-3-pyridincarbonyl) carbamic acid 2-(s)-hydroxymutilin 14-ester |
| CN101120001A (zh) * | 2004-12-27 | 2008-02-06 | 杏林制药株式会社 | 12位取代姆替林衍生物 |
| US20080139626A1 (en) * | 2005-03-10 | 2008-06-12 | Rittenhouse Stephen F | Novel Method |
| TW200738701A (en) | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
| KR100695541B1 (ko) * | 2005-10-31 | 2007-03-16 | 한국단자공업 주식회사 | 연결터미널 |
| WO2007079173A2 (en) * | 2005-12-30 | 2007-07-12 | Emergent Biosolutions Inc. | Novel 2-heteroaryloxy-phenol derivatives as antibacterial agents |
| US8222407B2 (en) * | 2007-05-24 | 2012-07-17 | Kyorin Pharmaceutical Co., Ltd. | Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position |
| EP2014640A1 (en) * | 2007-07-13 | 2009-01-14 | Nabriva Therapeutics AG | Pleuromutilin derivatives |
| JP2010100582A (ja) * | 2008-10-24 | 2010-05-06 | Kyorin Pharmaceut Co Ltd | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| EP2253617A1 (de) | 2009-05-20 | 2010-11-24 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| HRP20210010T1 (hr) * | 2015-06-17 | 2021-03-05 | Nabriva Therapeutics GmbH | Injekcijske farmaceutske formulacije lefamulina |
| CN113543827B (zh) * | 2019-02-27 | 2025-01-21 | 奥蒂卡拉股份有限公司 | 用于治疗鼻、鼻腔鼻窦和鼻咽组织感染和/或炎症的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997025309A1 (en) | 1996-01-03 | 1997-07-17 | Smithkline Beecham Plc | Carbamoyloxy derivatives of mutiline and their use as antibacterials |
| HUP0001741A3 (en) * | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
| UY25225A1 (es) | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
| FR2771008B1 (fr) | 1997-11-17 | 2000-04-28 | Hoechst Marion Roussel Inc | Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose |
| GB9817029D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Plc | Novel compounds |
-
2001
- 2001-03-29 WO PCT/EP2001/003594 patent/WO2001074788A1/en not_active Ceased
- 2001-03-29 NZ NZ521536A patent/NZ521536A/en unknown
- 2001-03-29 ES ES01938069T patent/ES2328109T3/es not_active Expired - Lifetime
- 2001-03-29 AU AU6382701A patent/AU6382701A/xx not_active Withdrawn
- 2001-03-29 AU AU2001263827A patent/AU2001263827B2/en not_active Ceased
- 2001-03-29 MX MXPA02009816A patent/MXPA02009816A/es active IP Right Grant
- 2001-03-29 AT AT01938069T patent/ATE437860T1/de not_active IP Right Cessation
- 2001-03-29 DE DE60139382T patent/DE60139382D1/de not_active Expired - Lifetime
- 2001-03-29 KR KR1020027013202A patent/KR100758441B1/ko not_active Expired - Fee Related
- 2001-03-29 EP EP01938069A patent/EP1268443B1/en not_active Expired - Lifetime
- 2001-03-29 HU HU0300370A patent/HUP0300370A3/hu unknown
- 2001-03-29 BR BR0109809-8A patent/BR0109809A/pt not_active Application Discontinuation
- 2001-03-29 CZ CZ20023290A patent/CZ20023290A3/cs unknown
- 2001-03-29 CA CA002405132A patent/CA2405132A1/en not_active Abandoned
- 2001-03-29 JP JP2001572483A patent/JP2003529593A/ja active Pending
- 2001-03-29 US US10/240,908 patent/US6972297B2/en not_active Expired - Fee Related
- 2001-03-29 IL IL15188701A patent/IL151887A0/xx unknown
- 2001-03-29 CN CNB018091989A patent/CN1210267C/zh not_active Expired - Fee Related
- 2001-03-29 PL PL01358666A patent/PL358666A1/xx not_active Application Discontinuation
- 2001-03-30 AR ARP010101559A patent/AR030203A1/es not_active Application Discontinuation
- 2001-03-30 CO CO01025487A patent/CO5280223A1/es not_active Application Discontinuation
-
2002
- 2002-10-02 NO NO20024745A patent/NO324229B1/no unknown
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