JP2003527311A5 - - Google Patents
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- JP2003527311A5 JP2003527311A5 JP2000614293A JP2000614293A JP2003527311A5 JP 2003527311 A5 JP2003527311 A5 JP 2003527311A5 JP 2000614293 A JP2000614293 A JP 2000614293A JP 2000614293 A JP2000614293 A JP 2000614293A JP 2003527311 A5 JP2003527311 A5 JP 2003527311A5
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- JP
- Japan
- Prior art keywords
- composition
- tissue
- amino acid
- acid sequence
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/301,808 US6664227B1 (en) | 1996-03-01 | 1999-04-28 | Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains |
| US09/301,808 | 1999-04-28 | ||
| PCT/US2000/011612 WO2000064944A1 (en) | 1999-04-28 | 2000-04-28 | Treatment of fibrosis by antagonism of il-13 and il-13 receptor chains |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011002569A Division JP2011078432A (ja) | 1999-04-28 | 2011-01-07 | Ｉｌ−１３およびｉｌ−１３レセプター鎖の拮抗による線維症の処置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003527311A JP2003527311A (ja) | 2003-09-16 |
| JP2003527311A5 true JP2003527311A5 (https=) | 2007-06-21 |
| JP4988988B2 JP4988988B2 (ja) | 2012-08-01 |
Family
ID=23164976
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000614293A Expired - Lifetime JP4988988B2 (ja) | 1999-04-28 | 2000-04-28 | Ｉｌ−１３およびｉｌ−１３レセプター鎖の拮抗による線維症の処置 |
| JP2011002569A Withdrawn JP2011078432A (ja) | 1999-04-28 | 2011-01-07 | Ｉｌ−１３およびｉｌ−１３レセプター鎖の拮抗による線維症の処置 |
| JP2013232738A Withdrawn JP2014087345A (ja) | 1999-04-28 | 2013-11-11 | Ｉｌ−１３およびｉｌ−１３レセプター鎖の拮抗による線維症の処置 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011002569A Withdrawn JP2011078432A (ja) | 1999-04-28 | 2011-01-07 | Ｉｌ−１３およびｉｌ−１３レセプター鎖の拮抗による線維症の処置 |
| JP2013232738A Withdrawn JP2014087345A (ja) | 1999-04-28 | 2013-11-11 | Ｉｌ−１３およびｉｌ−１３レセプター鎖の拮抗による線維症の処置 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US6664227B1 (https=) |
| EP (2) | EP1173484B1 (https=) |
| JP (3) | JP4988988B2 (https=) |
| KR (1) | KR100862931B1 (https=) |
| CN (1) | CN1348465A (https=) |
| AT (1) | ATE515513T1 (https=) |
| AU (1) | AU780991B2 (https=) |
| BR (1) | BR0010061A (https=) |
| CA (1) | CA2370306C (https=) |
| DK (1) | DK1173484T3 (https=) |
| HU (1) | HU230582B1 (https=) |
| IL (2) | IL146082A0 (https=) |
| MX (1) | MXPA01011023A (https=) |
| NZ (1) | NZ515464A (https=) |
| PT (1) | PT1173484E (https=) |
| WO (1) | WO2000064944A1 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7553487B2 (en) | 1998-12-14 | 2009-06-30 | Genetics Institute, Llc | Method and compositions for treating asthma |
| MXPA01006006A (es) | 1998-12-14 | 2004-08-12 | Genetics Inst | Cadena receptora de citocina. |
| GB0105360D0 (en) * | 2001-03-03 | 2001-04-18 | Glaxo Group Ltd | Chimaeric immunogens |
| US7541040B2 (en) * | 2001-12-04 | 2009-06-02 | The United States Of America As Represented By The Department Of Health And Human Serivces | Chimeric molecule for the treatment of th2-like cytokine mediated disorders |
| AU2003223497A1 (en) * | 2002-04-05 | 2003-10-27 | Centocor, Inc. | Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses |
| ES2365210T3 (es) * | 2002-06-14 | 2011-09-26 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health | Procedimientos de tratamiento y prevención de colitis en la que se implican la il-13 y los linfocitos t citolíticos naturales. |
| US20070104710A1 (en) * | 2002-06-28 | 2007-05-10 | Domants Limited | Ligand that has binding specificity for IL-4 and/or IL-13 |
| US20110223168A1 (en) * | 2002-12-27 | 2011-09-15 | Greg Winter | Ligand that has binding specificity for il-4 and/or il-13 |
| EP1444989A1 (en) * | 2003-02-07 | 2004-08-11 | Giorgio Dr. Stassi | Sensitizing cells for apoptosis by selectively blocking cytokines |
| GB0407315D0 (en) | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| PL3718564T3 (pl) * | 2003-12-23 | 2024-03-18 | Genentech, Inc. | Nowe przeciwciała anty-IL 13 i ich zastosowania |
| EP1713441A2 (en) * | 2004-02-12 | 2006-10-25 | Nektar Therapeutics | Interleukin-13 antagonist powders, spray-dried particles, and methods |
| EP1734970B1 (en) | 2004-03-12 | 2014-12-31 | Intercept Pharmaceuticals, Inc. | Treatment of fibrosis using fxr ligands |
| MXPA06014091A (es) * | 2004-06-04 | 2007-01-31 | Wyeth Corp | Inhibidores de proteinas regiii como substancias terapeuticas para el asma. |
| US7501121B2 (en) * | 2004-06-17 | 2009-03-10 | Wyeth | IL-13 binding agents |
| US20090098142A1 (en) * | 2004-06-09 | 2009-04-16 | Kasaian Marion T | Methods and compositions for treating and monitoring treatment of IL-13-associated disorders |
| AR049390A1 (es) * | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| EP1824886B1 (en) | 2004-11-17 | 2010-12-22 | Amgen Inc. | Fully human monoclonal antibodies to il-13 |
| JP4465469B2 (ja) * | 2005-02-21 | 2010-05-19 | 国立大学法人佐賀大学 | 循環器病マーカーとしてのインターロイキン１３ |
| WO2006124451A2 (en) * | 2005-05-11 | 2006-11-23 | Centocor, Inc. | Anti-il-13 antibodies, compositions, methods and uses |
| US7666622B2 (en) * | 2005-10-19 | 2010-02-23 | Regeneron Pharmaceuticals, Inc. | Monomeric self-associating fusion polypeptides and therapeutic uses thereof |
| WO2007045477A2 (en) | 2005-10-21 | 2007-04-26 | Novartis Ag | Human antibodies against il-13 and therapeutic uses |
| WO2007147600A2 (en) * | 2006-06-21 | 2007-12-27 | Apogenix Gmbh | Differential il-4 and/or il-10 cytokine expression in human cancer |
| US20100086515A1 (en) * | 2006-07-06 | 2010-04-08 | Apogenix Gmbh | Human il-4 muteins in cancer therapy |
| GB0615881D0 (en) * | 2006-08-10 | 2006-09-20 | Univ Southampton | Novel peptide for treatment of asthma |
| JP2010502224A (ja) * | 2006-09-08 | 2010-01-28 | アボット・ラボラトリーズ | インターロイキン１３結合タンパク質 |
| EA200970588A1 (ru) * | 2006-12-15 | 2009-12-30 | Сентокор Орто Байотек Инк. | Способы и композиции для лечения патологий, связанных с опосредуемым il-4 или il-13 фиброзом |
| AR066240A1 (es) * | 2007-04-23 | 2009-08-05 | Wyeth Corp | Metodos y composiciones para tratar y monitorear el tratamiento de trastornos asociados con il-13 |
| EP2050764A1 (en) | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| US8092804B2 (en) | 2007-12-21 | 2012-01-10 | Medimmune Limited | Binding members for interleukin-4 receptor alpha (IL-4Rα)-173 |
| CN101318013B (zh) * | 2008-07-17 | 2013-04-10 | 四川大学 | Il-4在制备治疗慢性肝纤维化的药物组合物中的用途 |
| EA201170357A1 (ru) | 2008-08-20 | 2012-05-30 | Сентокор Орто Байотек Инк. | Инженерные антитела к il-13: композиции, способы и применение |
| GB0904214D0 (en) | 2009-03-11 | 2009-04-22 | Ucb Pharma Sa | Biological products |
| TWI719112B (zh) | 2011-03-16 | 2021-02-21 | 賽諾菲公司 | 雙重ｖ區類抗體蛋白質之用途 |
| PT2953948T (pt) | 2013-02-07 | 2017-12-12 | Scifluor Life Sciences Inc | Antagonistas de integrina fluorada |
| RU2016107435A (ru) | 2013-09-13 | 2017-10-18 | Дженентек, Инк. | Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты |
| CN120904322A (zh) | 2013-09-13 | 2025-11-07 | 豪夫迈·罗氏有限公司 | 包含纯化的重组多肽的方法和组合物 |
| TW201628647A (zh) * | 2014-06-27 | 2016-08-16 | 賽諾菲公司 | 抗－ｉｌ４－ｉｌ１３雙特異性抗體 |
| EP3194446B1 (en) | 2014-09-18 | 2022-10-26 | Cedars-Sinai Medical Center | Compositions and methods for treating fibrosis |
| AU2015346150B2 (en) * | 2014-11-14 | 2021-08-19 | Regeneron Pharmaceuticals, Inc. | Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist |
| US9790222B2 (en) | 2015-02-19 | 2017-10-17 | Scifluor Life Sciences, Inc. | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof |
| BR112017023432A2 (pt) | 2015-04-30 | 2018-07-24 | Scifluor Life Sciences Inc | Derivados de ácido propiônico tetra- hidronaftiridinila e usos do mesmo |
| CN105052892A (zh) * | 2015-07-20 | 2015-11-18 | 山东省齐鲁干细胞工程有限公司 | 一种无dmso的冷冻保护剂与冷冻保存卵巢的方法 |
| EP3433615A1 (en) | 2016-03-21 | 2019-01-30 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Methods for diagnosis and treatment of solar lentigo |
| US10118929B2 (en) | 2016-04-27 | 2018-11-06 | Scifluor Life Sciences, Inc. | Nonanoic and decanoic acid derivatives and uses thereof |
| CN110540590B (zh) | 2018-05-29 | 2023-08-18 | 康诺亚生物医药科技（成都）有限公司 | 一种自免疫抑制物的开发和应用 |
| WO2021249555A1 (en) * | 2020-06-12 | 2021-12-16 | Beijing Vdjbio Co., Ltd. | Fusion polypeptide |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4737323A (en) | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| GB8927546D0 (en) | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| WO1994004680A1 (en) | 1992-08-21 | 1994-03-03 | Schering Corporation | Human interleukin-13 |
| HUT76369A (en) | 1994-07-29 | 1997-08-28 | Smithkline Beecham Corp | Novel soluble protein compounds |
| US5710023A (en) | 1996-03-01 | 1998-01-20 | Genetics Institute, Inc. | IL-13 cytokine receptor chain |
| WO1997033913A1 (en) | 1996-03-13 | 1997-09-18 | Zymogenetics, Inc. | Cytokine-receptor expressed in testis cells |
| WO1997047741A1 (en) | 1996-06-12 | 1997-12-18 | Smithkline Beecham Corporation | Hr-1 receptor |
| EP0812913A3 (en) | 1996-06-12 | 1999-08-04 | Smithkline Beecham Corporation | HR-1 receptor, a receptor of the cytokine receptors family |
| WO1997047742A1 (en) | 1996-06-12 | 1997-12-18 | Smithkline Beecham Corporation | Hr-1 receptor |
| WO1998010638A1 (en) | 1996-09-10 | 1998-03-19 | Amrad Operations Pty. Ltd. | Therapeutic molecules |
-
1999
- 1999-04-28 US US09/301,808 patent/US6664227B1/en not_active Expired - Lifetime
-
2000
- 2000-04-28 BR BR0010061-7A patent/BR0010061A/pt not_active Application Discontinuation
- 2000-04-28 CA CA2370306A patent/CA2370306C/en not_active Expired - Lifetime
- 2000-04-28 KR KR1020017013820A patent/KR100862931B1/ko not_active Expired - Fee Related
- 2000-04-28 MX MXPA01011023A patent/MXPA01011023A/es active IP Right Grant
- 2000-04-28 EP EP00928591A patent/EP1173484B1/en not_active Revoked
- 2000-04-28 AT AT00928591T patent/ATE515513T1/de active
- 2000-04-28 IL IL14608200A patent/IL146082A0/xx unknown
- 2000-04-28 CN CN00806772A patent/CN1348465A/zh active Pending
- 2000-04-28 WO PCT/US2000/011612 patent/WO2000064944A1/en not_active Ceased
- 2000-04-28 NZ NZ515464A patent/NZ515464A/xx not_active IP Right Cessation
- 2000-04-28 HU HU0200862A patent/HU230582B1/hu unknown
- 2000-04-28 EP EP09169462A patent/EP2123674A1/en not_active Ceased
- 2000-04-28 PT PT00928591T patent/PT1173484E/pt unknown
- 2000-04-28 AU AU46805/00A patent/AU780991B2/en not_active Expired
- 2000-04-28 DK DK00928591.7T patent/DK1173484T3/da active
- 2000-04-28 JP JP2000614293A patent/JP4988988B2/ja not_active Expired - Lifetime
-
2001
- 2001-10-21 IL IL146082A patent/IL146082A/en not_active IP Right Cessation
-
2003
- 2003-09-25 US US10/671,034 patent/US7282206B2/en not_active Expired - Lifetime
-
2011
- 2011-01-07 JP JP2011002569A patent/JP2011078432A/ja not_active Withdrawn
-
2013
- 2013-11-11 JP JP2013232738A patent/JP2014087345A/ja not_active Withdrawn
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