KR100862931B1 - Ｉｌ-13 및 ｉｌ-13 수용체 사슬의 길항작용에 의한섬유증의 치료 방법 - Google Patents

Ｉｌ-13 및 ｉｌ-13 수용체 사슬의 길항작용에 의한섬유증의 치료 방법 Download PDF

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KR100862931B1
KR100862931B1 KR1020017013820A KR20017013820A KR100862931B1 KR 100862931 B1 KR100862931 B1 KR 100862931B1 KR 1020017013820 A KR1020017013820 A KR 1020017013820A KR 20017013820 A KR20017013820 A KR 20017013820A KR 100862931 B1 KR100862931 B1 KR 100862931B1
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tissue
pharmaceutical composition
fibrosis
mammalian subject
seq
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KR20020026426A (ko
Inventor
윈토마스에이
치아라몽트모니카지
콜린스마리
도날드슨데브라
피츠로리
네벤탐린
위터스매튜제이
우드클리브
Original Assignee
제네틱스 인스티튜트, 엘엘씨
더 거번먼트 오브 더 유나이티드 스테이츠 오브 어메리카 애즈 레프리젠티드 바이 더 세크러터리 오브 더 디파트먼트 오브 헬쓰 앤드 휴먼 써비시즈
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Application filed by 제네틱스 인스티튜트, 엘엘씨, 더 거번먼트 오브 더 유나이티드 스테이츠 오브 어메리카 애즈 레프리젠티드 바이 더 세크러터리 오브 더 디파트먼트 오브 헬쓰 앤드 휴먼 써비시즈 filed Critical 제네틱스 인스티튜트, 엘엘씨
Publication of KR20020026426A publication Critical patent/KR20020026426A/ko
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    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Biochemistry (AREA)
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  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cardiology (AREA)
KR1020017013820A 1999-04-28 2000-04-28 Ｉｌ-13 및 ｉｌ-13 수용체 사슬의 길항작용에 의한섬유증의 치료 방법 Expired - Fee Related KR100862931B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/301,808 US6664227B1 (en) 1996-03-01 1999-04-28 Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains
US09/301,808 1999-04-28

Publications (2)

Publication Number Publication Date
KR20020026426A KR20020026426A (ko) 2002-04-10
KR100862931B1 true KR100862931B1 (ko) 2008-10-13

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ID=23164976

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KR1020017013820A Expired - Fee Related KR100862931B1 (ko) 1999-04-28 2000-04-28 Ｉｌ-13 및 ｉｌ-13 수용체 사슬의 길항작용에 의한섬유증의 치료 방법

Country Status (16)

Country Link
US (2) US6664227B1 (https=)
EP (2) EP1173484B1 (https=)
JP (3) JP4988988B2 (https=)
KR (1) KR100862931B1 (https=)
CN (1) CN1348465A (https=)
AT (1) ATE515513T1 (https=)
AU (1) AU780991B2 (https=)
BR (1) BR0010061A (https=)
CA (1) CA2370306C (https=)
DK (1) DK1173484T3 (https=)
HU (1) HU230582B1 (https=)
IL (2) IL146082A0 (https=)
MX (1) MXPA01011023A (https=)
NZ (1) NZ515464A (https=)
PT (1) PT1173484E (https=)
WO (1) WO2000064944A1 (https=)

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WO2006124451A2 (en) * 2005-05-11 2006-11-23 Centocor, Inc. Anti-il-13 antibodies, compositions, methods and uses
US7666622B2 (en) * 2005-10-19 2010-02-23 Regeneron Pharmaceuticals, Inc. Monomeric self-associating fusion polypeptides and therapeutic uses thereof
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WO1997031946A1 (en) * 1996-03-01 1997-09-04 Genetics Institute, Inc. Il-13 binding chain of il-13 receptor

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HUP0200862A3 (en) 2004-11-29
HU230582B1 (hu) 2017-01-30
JP2003527311A (ja) 2003-09-16
NZ515464A (en) 2004-02-27
HUP0200862A2 (hu) 2002-07-29
EP2123674A1 (en) 2009-11-25
BR0010061A (pt) 2003-02-25
JP2011078432A (ja) 2011-04-21
AU780991B2 (en) 2005-04-28
EP1173484B1 (en) 2011-07-06
DK1173484T3 (da) 2011-10-03
MXPA01011023A (es) 2002-05-06
IL146082A0 (en) 2002-07-25
PT1173484E (pt) 2011-09-29
KR20020026426A (ko) 2002-04-10
US7282206B2 (en) 2007-10-16
CN1348465A (zh) 2002-05-08
AU4680500A (en) 2000-11-10
WO2000064944A1 (en) 2000-11-02
CA2370306C (en) 2014-06-17
CA2370306A1 (en) 2000-11-02
IL146082A (en) 2014-08-31
JP2014087345A (ja) 2014-05-15
JP4988988B2 (ja) 2012-08-01
US6664227B1 (en) 2003-12-16
EP1173484A1 (en) 2002-01-23
ATE515513T1 (de) 2011-07-15
US20050096268A1 (en) 2005-05-05
EP1173484A4 (en) 2003-05-21

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