JP2003525902A - 耐性および依存症を治療するための代謝共役型グルタミン酸受容体アンタゴニスト - Google Patents
耐性および依存症を治療するための代謝共役型グルタミン酸受容体アンタゴニストInfo
- Publication number
- JP2003525902A JP2003525902A JP2001564765A JP2001564765A JP2003525902A JP 2003525902 A JP2003525902 A JP 2003525902A JP 2001564765 A JP2001564765 A JP 2001564765A JP 2001564765 A JP2001564765 A JP 2001564765A JP 2003525902 A JP2003525902 A JP 2003525902A
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- Prior art keywords
- addiction
- mglur5
- product
- substance
- antagonist
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2020529975A (ja) * | 2017-07-31 | 2020-10-15 | ノバルティス アーゲー | コカイン使用の低減又はコカイン使用再燃の予防におけるマボグルラントの使用 |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2498022C (en) * | 2002-09-10 | 2012-10-23 | Novartis Ag | Combination of mglur antagonists for the treatment of addictive disorders |
| PL2982372T3 (pl) | 2005-04-05 | 2020-12-28 | Yale University | Środki modulujące stężenie glutaminianu stosowane w leczeniu zaburzeń psychicznych |
| US20060264381A1 (en) * | 2005-05-05 | 2006-11-23 | Bear Mark F | Methods of treating obsessive compulsive disorder |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| US7678363B2 (en) | 2005-08-26 | 2010-03-16 | Braincells Inc | Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs |
| WO2007035823A2 (en) * | 2005-09-20 | 2007-03-29 | Molecular Neuroimaging, Llc | Partial mglur5 antagonists and methods of use thereof |
| EP2377530A3 (en) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| EP1942879A1 (en) | 2005-10-31 | 2008-07-16 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| DE102005062985A1 (de) * | 2005-12-28 | 2007-07-05 | Grünenthal GmbH | Substituierte bis(hetero)aromatische N-Ethylpropiolamide und ihre Verwendung zur Herstellung von Arzneimitteln |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| WO2007134136A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| RS55585B1 (sr) | 2006-11-22 | 2017-06-30 | Clinical Research Associates LLC | Postupci za lečenje daunovog sindroma, krhkog x sindroma i autizma |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| EP2544688B1 (en) | 2010-03-02 | 2016-09-07 | President and Fellows of Harvard College | Methods and compositions for treatment of angelman syndrome |
| WO2011150380A1 (en) | 2010-05-28 | 2011-12-01 | Xenoport, Inc. | Methods of treatment of fragile x syndrome, down's syndrome, autism and related disorders |
| US20120016021A1 (en) | 2010-07-15 | 2012-01-19 | Xenoport, Inc. | Methods of treating fragile x syndrome, down's syndrome, autism and related disorders |
| WO2012054724A1 (en) | 2010-10-21 | 2012-04-26 | Massachusetts Institute Of Technology | Methods of treating seizure disorders |
| US20130123254A1 (en) * | 2011-09-30 | 2013-05-16 | Barbara Biemans | Pharmaceutically acceptable mglur5 positive allosteric modulators and their methods of identification |
| GB201312800D0 (en) | 2013-07-17 | 2013-08-28 | Heptares Therapeutics Ltd | mGlu5 modulators |
| EP3661501A1 (en) | 2017-07-31 | 2020-06-10 | Novartis AG | Use of mavoglurant in the reduction of alcohol use or in preventing relapse into alcohol use |
| CN115942979A (zh) * | 2020-07-17 | 2023-04-07 | 诺华股份有限公司 | 在减少阿片类物质使用的治疗中使用的mglur5拮抗剂玛沃谷兰 |
| WO2022130136A1 (en) * | 2020-12-14 | 2022-06-23 | Novartis Ag | Use of mglur5 antagonists for treating gambling disorder |
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| US5958459A (en) * | 1991-12-24 | 1999-09-28 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
| US5543698A (en) * | 1994-09-27 | 1996-08-06 | Allen-Bradley Company, Inc. | Method and apparatus used with AC motor for detecting unbalance |
| GB9609976D0 (en) * | 1996-05-13 | 1996-07-17 | Lilly Industries Ltd | Pharmaceutical compounds |
| WO1998040407A1 (en) * | 1997-03-14 | 1998-09-17 | Johns Hopkins University | Synaptic activation protein compositions and method |
| TW544448B (en) * | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
| US6057368A (en) * | 1998-08-05 | 2000-05-02 | Brookhaven Science Associates Llc | Treatment of addiction and addiction-related behavior |
| DE69913548T2 (de) * | 1998-10-02 | 2004-09-23 | Novartis Ag | Mglur5 antagonisten zur behandlung von schmerzen und angstzuständen |
| TW593241B (en) * | 1999-04-20 | 2004-06-21 | Hoffmann La Roche | Carbamic acid derivatives |
| AU4797400A (en) * | 1999-05-17 | 2000-12-05 | Eli Lilly And Company | Metabotropic glutamate receptor antagonists |
| US6666209B2 (en) * | 2001-02-20 | 2003-12-23 | 3M Innovative Properties Company | Method and system of calibrating air flow in a respirator system |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020529975A (ja) * | 2017-07-31 | 2020-10-15 | ノバルティス アーゲー | コカイン使用の低減又はコカイン使用再燃の予防におけるマボグルラントの使用 |
| JP2023109917A (ja) * | 2017-07-31 | 2023-08-08 | ノバルティス アーゲー | コカイン使用の低減又はコカイン使用再燃の予防におけるマボグルラントの使用 |
| US11878001B2 (en) | 2017-07-31 | 2024-01-23 | Novartis Ag | Use of mavoglurant in the reduction of cocaine use or in preventing relapse into cocaine use |
| JP7645037B2 (ja) | 2017-07-31 | 2025-03-13 | ノバルティス アーゲー | コカイン使用の低減又はコカイン使用再燃の予防におけるマボグルラントの使用 |
Also Published As
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|---|---|
| TR200401862T4 (tr) | 2004-10-21 |
| DE60103384D1 (de) | 2004-06-24 |
| PT1267869E (pt) | 2004-10-29 |
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| CA2402341A1 (en) | 2001-09-13 |
| DK1267869T3 (da) | 2004-09-20 |
| DE60103384T2 (de) | 2005-06-16 |
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| AU783869B2 (en) | 2005-12-15 |
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| US20030195139A1 (en) | 2003-10-16 |
| CN1427720A (zh) | 2003-07-02 |
| EP1267869A1 (en) | 2003-01-02 |
| EP1267869B1 (en) | 2004-05-19 |
| HK1053262A1 (en) | 2003-10-17 |
| ATE267013T1 (de) | 2004-06-15 |
| WO2001066113A1 (en) | 2001-09-13 |
| AU3763401A (en) | 2001-09-17 |
| ES2220727T3 (es) | 2004-12-16 |
| GB0005700D0 (en) | 2000-05-03 |
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