JP2003525902A - 耐性および依存症を治療するための代謝共役型グルタミン酸受容体アンタゴニスト - Google Patents
耐性および依存症を治療するための代謝共役型グルタミン酸受容体アンタゴニストInfo
- Publication number
- JP2003525902A JP2003525902A JP2001564765A JP2001564765A JP2003525902A JP 2003525902 A JP2003525902 A JP 2003525902A JP 2001564765 A JP2001564765 A JP 2001564765A JP 2001564765 A JP2001564765 A JP 2001564765A JP 2003525902 A JP2003525902 A JP 2003525902A
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- Prior art keywords
- addiction
- mglur5
- product
- substance
- antagonist
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
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Landscapes
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2020529975A (ja) * | 2017-07-31 | 2020-10-15 | ノバルティス アーゲー | コカイン使用の低減又はコカイン使用再燃の予防におけるマボグルラントの使用 |
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| WO2004024150A2 (en) * | 2002-09-10 | 2004-03-25 | Novartis Ag | Mglu receptors antagonists for treating disorders associated with mglu receptors including addiction and depression |
| DK2201963T3 (en) * | 2005-04-05 | 2016-02-15 | Univ Yale | Glutamate-modulating agents in the treatment of mental disorders |
| US20060264381A1 (en) * | 2005-05-05 | 2006-11-23 | Bear Mark F | Methods of treating obsessive compulsive disorder |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| WO2007035823A2 (en) * | 2005-09-20 | 2007-03-29 | Molecular Neuroimaging, Llc | Partial mglur5 antagonists and methods of use thereof |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| DE102005062985A1 (de) * | 2005-12-28 | 2007-07-05 | Grünenthal GmbH | Substituierte bis(hetero)aromatische N-Ethylpropiolamide und ihre Verwendung zur Herstellung von Arzneimitteln |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2026813A2 (en) | 2006-05-09 | 2009-02-25 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| WO2007134136A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US7998971B2 (en) | 2006-09-08 | 2011-08-16 | Braincells Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| ES2610508T3 (es) | 2006-11-22 | 2017-04-27 | Clinical Research Associates, Llc | Métodos para tratar el síndrome de Down, el síndrome del cromosoma X frágil y el autismo |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| US20130058915A1 (en) | 2010-03-02 | 2013-03-07 | Children's Medica Center Corporation | Methods and compositions for treatment of angelman syndrome and autism spectrum disorders |
| US20110294879A1 (en) | 2010-05-28 | 2011-12-01 | Xenoport, Inc. | Method of treatment of fragile x syndrome, down's syndrome, autism and related disorders |
| WO2012009646A1 (en) | 2010-07-15 | 2012-01-19 | Xenoport, Inc. | Methods of treating fragile x syndrome, down's syndrome, autism and related disorders |
| WO2012054724A1 (en) | 2010-10-21 | 2012-04-26 | Massachusetts Institute Of Technology | Methods of treating seizure disorders |
| US20130123254A1 (en) * | 2011-09-30 | 2013-05-16 | Barbara Biemans | Pharmaceutically acceptable mglur5 positive allosteric modulators and their methods of identification |
| GB201312800D0 (en) | 2013-07-17 | 2013-08-28 | Heptares Therapeutics Ltd | mGlu5 modulators |
| EP3661501B1 (en) | 2017-07-31 | 2026-01-07 | Novartis AG | Use of mavoglurant in the reduction of alcohol use or in preventing relapse into alcohol use |
| KR102850517B1 (ko) * | 2020-07-17 | 2025-08-25 | 노파르티스 아게 | 오피오이드 사용 감소 치료에 사용하기 위한 mglur5 길항제 마보글루란트 |
| US20240082215A1 (en) * | 2020-12-14 | 2024-03-14 | Novartis Ag | Use of mglur5 antagonists for treating gambling disorder |
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| US5958459A (en) * | 1991-12-24 | 1999-09-28 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
| US5543698A (en) * | 1994-09-27 | 1996-08-06 | Allen-Bradley Company, Inc. | Method and apparatus used with AC motor for detecting unbalance |
| GB9609976D0 (en) * | 1996-05-13 | 1996-07-17 | Lilly Industries Ltd | Pharmaceutical compounds |
| JP4127861B2 (ja) * | 1997-03-14 | 2008-07-30 | ジョンズ ホプキンス ユニバーシティー | シナプス活性化タンパク質組成物および方法 |
| TW544448B (en) * | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
| US6057368A (en) * | 1998-08-05 | 2000-05-02 | Brookhaven Science Associates Llc | Treatment of addiction and addiction-related behavior |
| ID29095A (id) * | 1998-10-02 | 2001-07-26 | Novartis Ag Cs | Antagonis mglur5 untuk pengobatan rasa sakit dan kegelisahan |
| TW593241B (en) * | 1999-04-20 | 2004-06-21 | Hoffmann La Roche | Carbamic acid derivatives |
| AU4797400A (en) * | 1999-05-17 | 2000-12-05 | Eli Lilly And Company | Metabotropic glutamate receptor antagonists |
| US6666209B2 (en) * | 2001-02-20 | 2003-12-23 | 3M Innovative Properties Company | Method and system of calibrating air flow in a respirator system |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020529975A (ja) * | 2017-07-31 | 2020-10-15 | ノバルティス アーゲー | コカイン使用の低減又はコカイン使用再燃の予防におけるマボグルラントの使用 |
| JP2023109917A (ja) * | 2017-07-31 | 2023-08-08 | ノバルティス アーゲー | コカイン使用の低減又はコカイン使用再燃の予防におけるマボグルラントの使用 |
| US11878001B2 (en) | 2017-07-31 | 2024-01-23 | Novartis Ag | Use of mavoglurant in the reduction of cocaine use or in preventing relapse into cocaine use |
| JP7645037B2 (ja) | 2017-07-31 | 2025-03-13 | ノバルティス アーゲー | コカイン使用の低減又はコカイン使用再燃の予防におけるマボグルラントの使用 |
Also Published As
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|---|---|
| TR200401862T4 (tr) | 2004-10-21 |
| DE60103384D1 (de) | 2004-06-24 |
| SE1267869T5 (enExample) | 2004-09-07 |
| EP1267869A1 (en) | 2003-01-02 |
| PT1267869E (pt) | 2004-10-29 |
| ATE267013T1 (de) | 2004-06-15 |
| GB0005700D0 (en) | 2000-05-03 |
| CN1427720A (zh) | 2003-07-02 |
| DE60103384T2 (de) | 2005-06-16 |
| DK1267869T3 (da) | 2004-09-20 |
| EP1267869B1 (en) | 2004-05-19 |
| NZ521228A (en) | 2004-04-30 |
| AU783869B2 (en) | 2005-12-15 |
| WO2001066113A1 (en) | 2001-09-13 |
| US20030195139A1 (en) | 2003-10-16 |
| CA2402341A1 (en) | 2001-09-13 |
| AU3763401A (en) | 2001-09-17 |
| ES2220727T3 (es) | 2004-12-16 |
| HK1053262A1 (en) | 2003-10-17 |
| SE1267869T3 (enExample) | 2004-08-31 |
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