JP2003523338A5 - - Google Patents
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- Publication number
- JP2003523338A5 JP2003523338A5 JP2001560195A JP2001560195A JP2003523338A5 JP 2003523338 A5 JP2003523338 A5 JP 2003523338A5 JP 2001560195 A JP2001560195 A JP 2001560195A JP 2001560195 A JP2001560195 A JP 2001560195A JP 2003523338 A5 JP2003523338 A5 JP 2003523338A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- compound
- formula
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052799 carbon Inorganic materials 0.000 description 15
- 150000001875 compounds Chemical class 0.000 description 12
- 125000003118 aryl group Chemical group 0.000 description 8
- 229910052736 halogen Inorganic materials 0.000 description 6
- 150000002367 halogens Chemical class 0.000 description 6
- 150000003839 salts Chemical class 0.000 description 5
- 125000006615 aromatic heterocyclic group Chemical group 0.000 description 4
- 239000000203 mixture Substances 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 125000000304 alkynyl group Chemical group 0.000 description 2
- 125000000623 heterocyclic group Chemical group 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002648 combination therapy Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0003629A GB0003629D0 (en) | 2000-02-16 | 2000-02-16 | Antitumour agent |
| GB0003629.3 | 2000-02-16 | ||
| GB0021774A GB0021774D0 (en) | 2000-09-05 | 2000-09-05 | Anti-tumour compound |
| GB0021774.5 | 2000-09-05 | ||
| PCT/GB2001/000655 WO2001060810A1 (en) | 2000-02-16 | 2001-02-16 | Oxy-and amino-substituted tetrahydrofuryl derivatives with antitumour activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003523338A JP2003523338A (ja) | 2003-08-05 |
| JP2003523338A5 true JP2003523338A5 (enExample) | 2008-03-27 |
Family
ID=26243662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001560195A Pending JP2003523338A (ja) | 2000-02-16 | 2001-02-16 | 抗腫瘍活性を有するオキシ−及びアミノ−置換テトラヒドロフリル誘導体 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6864283B2 (enExample) |
| EP (1) | EP1255746B1 (enExample) |
| JP (1) | JP2003523338A (enExample) |
| KR (1) | KR20020092958A (enExample) |
| CN (1) | CN1318409C (enExample) |
| AT (1) | ATE316524T1 (enExample) |
| AU (2) | AU2001233873B2 (enExample) |
| BR (1) | BR0108448A (enExample) |
| CA (1) | CA2400612C (enExample) |
| CZ (1) | CZ20022791A3 (enExample) |
| DE (1) | DE60116855T2 (enExample) |
| ES (1) | ES2256199T3 (enExample) |
| IL (1) | IL151241A (enExample) |
| MX (1) | MXPA02007995A (enExample) |
| PL (1) | PL357193A1 (enExample) |
| RU (1) | RU2002124591A (enExample) |
| WO (1) | WO2001060810A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02007995A (es) | 2000-02-16 | 2003-05-23 | Ruffles Graham Keith | Derivados de tetrahidrofurilo sustituidos por oxy y amino con actividad antitumoral. |
| CN102229585A (zh) * | 2011-04-26 | 2011-11-02 | 中国人民解放军第二军医大学 | 具有抗肿瘤活性的γ-丁内酯聚酮类化合物 |
| TWI807411B (zh) | 2017-04-27 | 2023-07-01 | 西班牙商瑪製藥股份有限公司 | 抗腫瘤化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5583160A (en) * | 1989-02-03 | 1996-12-10 | The Biomembrane Institute | Methylsphingosine used to treat apoptosis |
| CA2007507C (en) | 1989-02-03 | 1998-05-19 | Yasuyuki Igarashi | Sphingosine and n-methyl-sphingosine as inhibitor of cell growth |
| US6107520A (en) * | 1997-04-15 | 2000-08-22 | The Board Of Trustees Of The University Of Illinois | Spisulosine compounds |
| MXPA02007995A (es) | 2000-02-16 | 2003-05-23 | Ruffles Graham Keith | Derivados de tetrahidrofurilo sustituidos por oxy y amino con actividad antitumoral. |
-
2001
- 2001-02-16 MX MXPA02007995A patent/MXPA02007995A/es active IP Right Grant
- 2001-02-16 KR KR1020027010697A patent/KR20020092958A/ko not_active Ceased
- 2001-02-16 WO PCT/GB2001/000655 patent/WO2001060810A1/en not_active Ceased
- 2001-02-16 US US10/203,918 patent/US6864283B2/en not_active Expired - Fee Related
- 2001-02-16 BR BR0108448-8A patent/BR0108448A/pt not_active IP Right Cessation
- 2001-02-16 AU AU2001233873A patent/AU2001233873B2/en not_active Ceased
- 2001-02-16 AT AT01905903T patent/ATE316524T1/de not_active IP Right Cessation
- 2001-02-16 JP JP2001560195A patent/JP2003523338A/ja active Pending
- 2001-02-16 ES ES01905903T patent/ES2256199T3/es not_active Expired - Lifetime
- 2001-02-16 DE DE60116855T patent/DE60116855T2/de not_active Expired - Lifetime
- 2001-02-16 AU AU3387301A patent/AU3387301A/xx active Pending
- 2001-02-16 RU RU2002124591/04A patent/RU2002124591A/ru not_active Application Discontinuation
- 2001-02-16 CN CNB018080421A patent/CN1318409C/zh not_active Expired - Fee Related
- 2001-02-16 EP EP01905903A patent/EP1255746B1/en not_active Expired - Lifetime
- 2001-02-16 PL PL01357193A patent/PL357193A1/xx not_active Application Discontinuation
- 2001-02-16 CZ CZ20022791A patent/CZ20022791A3/cs unknown
- 2001-02-16 CA CA2400612A patent/CA2400612C/en not_active Expired - Fee Related
-
2002
- 2002-08-13 IL IL151241A patent/IL151241A/en not_active IP Right Cessation
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