JP2003514935A - ポリ（ジアリルアミン）ポリマー類の使用 - Google Patents

ポリ（ジアリルアミン）ポリマー類の使用

Info

Publication number
JP2003514935A
JP2003514935A JP2001538997A JP2001538997A JP2003514935A JP 2003514935 A JP2003514935 A JP 2003514935A JP 2001538997 A JP2001538997 A JP 2001538997A JP 2001538997 A JP2001538997 A JP 2001538997A JP 2003514935 A JP2003514935 A JP 2003514935A
Authority
JP
Japan
Prior art keywords
polymer
formula
diallylamine
poly
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001538997A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003514935A5 (enExample
Inventor
グツドバイ，ジヨン・ウイリアム
ホール，アラン・ウイリアム
ミレン，ポール・エドワード・ヤング
ブラツクウツド，キース・モーリイ
Original Assignee
キネテイツク・リミテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by キネテイツク・リミテツド filed Critical キネテイツク・リミテツド
Publication of JP2003514935A publication Critical patent/JP2003514935A/ja
Publication of JP2003514935A5 publication Critical patent/JP2003514935A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/0605—Polycondensates containing five-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
    • C08G73/0611—Polycondensates containing five-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms with only one nitrogen atom in the ring, e.g. polypyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/12—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2001538997A 1999-11-17 2000-11-10 ポリ（ジアリルアミン）ポリマー類の使用 Pending JP2003514935A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9927088.6 1999-11-17
GBGB9927088.6A GB9927088D0 (en) 1999-11-17 1999-11-17 Use of poly(diallylamine) polymers
PCT/GB2000/004308 WO2001036510A2 (en) 1999-11-17 2000-11-10 Use of poly(diallylamine) polymers

Publications (2)

Publication Number Publication Date
JP2003514935A true JP2003514935A (ja) 2003-04-22
JP2003514935A5 JP2003514935A5 (enExample) 2007-12-20

Family

ID=10864611

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001538997A Pending JP2003514935A (ja) 1999-11-17 2000-11-10 ポリ（ジアリルアミン）ポリマー類の使用

Country Status (9)

Country Link
US (1) US7767229B1 (enExample)
EP (1) EP1265942B1 (enExample)
JP (1) JP2003514935A (enExample)
AT (1) ATE287911T1 (enExample)
AU (1) AU772653B2 (enExample)
CA (1) CA2391539C (enExample)
DE (1) DE60017805T2 (enExample)
GB (1) GB9927088D0 (enExample)
WO (1) WO2001036510A2 (enExample)

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Publication number Priority date Publication date Assignee Title
GB0606016D0 (en) * 2006-03-25 2006-05-03 Ionic Polymer Solutions Ltd Quaternary ammonium compounds and their uses
GB0613013D0 (en) 2006-06-30 2006-08-09 Novel Polymer Solutions Ltd Polymeric Materials and Methods for Manufacturing Them
DE102010002141A1 (de) 2010-02-19 2011-08-25 Momentive Performance Materials GmbH, 51373 Integrale Bestrahlungseinheit
WO2012017233A1 (en) 2010-08-02 2012-02-09 Novel Polymer Solutions Limited Methods of coating a low surface energy substrate
JP5986081B2 (ja) 2010-08-02 2016-09-06 シンター ファイン ケミカルズ リミテッド 複合部材及びその製造方法
WO2012017235A1 (en) 2010-08-02 2012-02-09 Novel Polymer Solutions Limited Covered floors and methods of adhering flooring to a floor
MX366925B (es) 2010-11-04 2019-07-31 Albireo Ab Inhibidores de ibat para el tratamiento de enfermedades hepaticas.
GB201105453D0 (en) 2011-03-31 2011-05-18 Novel Polymer Solutions Ltd Window frames, structural elements for a roofed construction and methods of assembling same
CN103732374B (zh) 2011-08-18 2018-10-30 迈图高新材料股份有限公司 照射和成型单元
GB201115823D0 (en) 2011-09-13 2011-10-26 Novel Polymer Solutions Ltd Mineral processing
WO2013186185A1 (de) 2012-06-11 2013-12-19 Momentive Performance Materials Gmbh Verfahren zur herstellung von kunststoff-verbundformkörpern
KR102633597B1 (ko) 2013-06-05 2024-02-06 트리시다, 인크. 경구 투여를 위한 양성자-결합 중합체
CA2952406A1 (en) 2014-06-25 2015-12-30 Ea Pharma Co., Ltd. Solid formulation and method for preventing or reducing coloration thereof
IL322207A (en) 2014-12-10 2025-09-01 Tricida Inc Proton-binding polymers for oral administration
CN108601744B (zh) 2016-02-09 2022-01-04 阿尔比里奥公司 口服考来烯胺制剂及其用途
JP6954927B2 (ja) 2016-02-09 2021-10-27 アルビレオ・アクチボラグ 経口コレスチラミン製剤及びその使用
CA3011595C (en) 2016-02-09 2024-01-02 Albireo Ab Cholestyramine pellets and methods for preparation thereof
IL262660B2 (en) 2016-05-06 2024-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
CN111032019B (zh) 2017-08-09 2022-07-05 阿尔比里奥公司 考来烯胺颗粒、口服考来烯胺制剂及其用途
US10934380B1 (en) 2017-09-25 2021-03-02 Tricida, Inc. Crosslinked poly(allylamine) polymer pharmaceutical compositions
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
JP7391048B2 (ja) 2018-06-05 2023-12-04 アルビレオ・アクチボラグ ベンゾチア（ジ）アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
KR20210024033A (ko) 2018-06-20 2021-03-04 알비레오 에이비 오데빅시바트의 약학 제제
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
SG11202108566VA (en) 2019-02-06 2021-09-29 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
CN113453753B (zh) 2019-02-06 2024-07-23 阿尔比里奥公司 苯并硫氮杂环庚三烯化合物及其用作胆汁酸调节剂的用途
CN114786772B (zh) 2019-12-04 2024-04-09 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
CA3158181A1 (en) 2019-12-04 2021-06-10 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
WO2021110885A1 (en) 2019-12-04 2021-06-10 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
JP7665621B2 (ja) 2019-12-04 2025-04-21 アルビレオ・アクチボラグ ベンゾチアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
CA3158195A1 (en) 2019-12-04 2021-06-10 Per-Goran Gillberg Benzothia(di)azepine compounds and their use as bile acid modulators
ES3002777T3 (en) 2020-08-03 2025-03-07 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
AU2021379076A1 (en) 2020-11-12 2023-06-08 Albireo Ab Odevixibat for treating progressive familial intrahepatic cholestasis (pfic)
BR112023010799A2 (pt) 2020-12-04 2023-10-03 Albireo Ab Compostos de benzotia(di)azepina e seus usos como moduladores de ácidos biliares
CN117412955A (zh) 2021-06-03 2024-01-16 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5035279A (enExample) * 1973-06-12 1975-04-03
JPS51136774A (en) * 1975-05-07 1976-11-26 Ici Australia Ltd Polymerization method of allyl amine monomer mixture
JPS6422924A (en) * 1987-06-25 1989-01-25 Hercules Inc Method for lowering serum cholesterol by polydiarylmethylamine derivative
WO1998029107A2 (en) * 1996-12-30 1998-07-09 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
WO1999022744A1 (en) * 1997-11-05 1999-05-14 Geltex Pharmaceuticals, Inc. Use of aliphatic polyamines for reducing oxalate
WO1999022721A2 (en) * 1997-11-05 1999-05-14 Geltex Pharmaceuticals, Inc. Unsubstituted polydiallylamine for treating hypercholesterolemia
JP2000034325A (ja) * 1998-07-02 2000-02-02 Natl Starch & Chem Investment Holding Corp アリル化アミド化合物製のパッケ―ジ封入剤
JP2000143597A (ja) * 1998-07-02 2000-05-23 Natl Starch & Chem Investment Holding Corp アリル化アミド化合物および前記化合物から製造されるダイアタッチ接着剤
JP2002521531A (ja) * 1998-07-25 2002-07-16 イギリス国 ポリマー製造
JP2002521529A (ja) * 1998-07-25 2002-07-16 イギリス国 単量体及び、それらから得られる網状高分子

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE520401A (enExample) * 1952-06-03
JPS5747302A (en) * 1980-09-03 1982-03-18 Mitsubishi Petrochem Co Ltd Preparation of crosslinkable electrolytic polymer
JPS62257481A (ja) 1986-04-30 1987-11-10 三洋化成工業株式会社 染料固着剤
JPH021358A (ja) * 1988-03-01 1990-01-05 Sanyo Chem Ind Ltd インクジェット記録紙用薬剤
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5035279A (enExample) * 1973-06-12 1975-04-03
JPS51136774A (en) * 1975-05-07 1976-11-26 Ici Australia Ltd Polymerization method of allyl amine monomer mixture
JPS6422924A (en) * 1987-06-25 1989-01-25 Hercules Inc Method for lowering serum cholesterol by polydiarylmethylamine derivative
WO1998029107A2 (en) * 1996-12-30 1998-07-09 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
WO1999022744A1 (en) * 1997-11-05 1999-05-14 Geltex Pharmaceuticals, Inc. Use of aliphatic polyamines for reducing oxalate
WO1999022721A2 (en) * 1997-11-05 1999-05-14 Geltex Pharmaceuticals, Inc. Unsubstituted polydiallylamine for treating hypercholesterolemia
JP2000034325A (ja) * 1998-07-02 2000-02-02 Natl Starch & Chem Investment Holding Corp アリル化アミド化合物製のパッケ―ジ封入剤
JP2000143597A (ja) * 1998-07-02 2000-05-23 Natl Starch & Chem Investment Holding Corp アリル化アミド化合物および前記化合物から製造されるダイアタッチ接着剤
JP2002521531A (ja) * 1998-07-25 2002-07-16 イギリス国 ポリマー製造
JP2002521529A (ja) * 1998-07-25 2002-07-16 イギリス国 単量体及び、それらから得られる網状高分子

Also Published As

Publication number Publication date
ATE287911T1 (de) 2005-02-15
CA2391539C (en) 2009-08-11
EP1265942A2 (en) 2002-12-18
WO2001036510A3 (en) 2002-09-12
GB9927088D0 (en) 2000-01-12
US7767229B1 (en) 2010-08-03
EP1265942B1 (en) 2005-01-26
AU1289301A (en) 2001-05-30
WO2001036510A2 (en) 2001-05-25
DE60017805T2 (de) 2006-01-12
DE60017805D1 (de) 2005-03-03
AU772653B2 (en) 2004-05-06
CA2391539A1 (en) 2001-05-25

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