JP2003511014A5 - - Google Patents
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- Publication number
- JP2003511014A5 JP2003511014A5 JP2001526577A JP2001526577A JP2003511014A5 JP 2003511014 A5 JP2003511014 A5 JP 2003511014A5 JP 2001526577 A JP2001526577 A JP 2001526577A JP 2001526577 A JP2001526577 A JP 2001526577A JP 2003511014 A5 JP2003511014 A5 JP 2003511014A5
- Authority
- JP
- Japan
- Prior art keywords
- xaa
- ala
- arg
- leu
- unsure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15692799P | 1999-09-29 | 1999-09-29 | |
| US60/156,927 | 1999-09-29 | ||
| PCT/US2000/004716 WO2001023427A1 (en) | 1999-09-29 | 2000-02-25 | Polypeptide derivatives of parathyroid hormone (pth) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003511014A JP2003511014A (ja) | 2003-03-25 |
| JP2003511014A5 true JP2003511014A5 (https=) | 2010-12-24 |
| JP4723144B2 JP4723144B2 (ja) | 2011-07-13 |
Family
ID=22561687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001526577A Expired - Fee Related JP4723144B2 (ja) | 1999-09-29 | 2000-02-25 | 副甲状腺ホルモン（ｐｔｈ）のポリペプチド誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP2030986A1 (https=) |
| JP (1) | JP4723144B2 (https=) |
| AT (1) | ATE412670T1 (https=) |
| DE (1) | DE60040678D1 (https=) |
| ES (1) | ES2316354T3 (https=) |
| WO (1) | WO2001023427A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69942035D1 (de) | 1998-11-25 | 2010-04-01 | Gen Hospital Corp | Menschliches parathyroidhormon, modifikationen, herstellung und verwendung |
| AU4217299A (en) | 1998-11-30 | 2000-06-19 | General Hospital Corporation, The | Pth1r and pth3r receptors, methods and uses thereof |
| EP1141237B1 (en) | 1998-12-31 | 2005-11-02 | The General Hospital Corporation | Pth receptor and screening assay utilizing the same |
| US6756480B2 (en) | 2000-04-27 | 2004-06-29 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| CA2454275C (en) | 2001-07-23 | 2012-10-23 | The General Hospital Corporation | Conformationally constrained parathyroid hormone (pth) analogs |
| AU2003217243A1 (en) * | 2003-01-24 | 2004-08-23 | Thomas J. Gardella | Conformationally constrained parathyroid hormone (pth) analogs with lactam bridges |
| AU2008282805B2 (en) | 2007-08-01 | 2014-05-01 | Chugai Pharmaceutical Co., Ltd. | Screening methods using G-protein coupled receptors and related compositions |
| FR2940292B1 (fr) * | 2008-12-23 | 2013-05-10 | Isp Investments Inc | Peptides derives d'hmg-coa reductase et composition cosmetique et/ou pharmaceutique les contenant |
| EP2411038B1 (en) | 2009-03-27 | 2016-12-28 | Van Andel Research Institute | Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use |
| SG174532A1 (en) * | 2009-04-24 | 2011-10-28 | Cadila Healthcare Ltd | Short-chain peptides as parathyroid hormone (pth) receptor agonist |
| WO2011143406A2 (en) | 2010-05-13 | 2011-11-17 | The General Hospital Corporation | Parathyroid hormone analogs and uses thereof |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4086196A (en) * | 1975-03-28 | 1978-04-25 | Armour Pharmaceutical Company | Parathyroid hormone |
| US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US4620948A (en) | 1982-12-22 | 1986-11-04 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4512922A (en) | 1982-12-22 | 1985-04-23 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4511502A (en) | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4518526A (en) | 1982-12-22 | 1985-05-21 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4736866B1 (en) | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
| IL78342A (en) | 1985-04-04 | 1991-06-10 | Gen Hospital Corp | Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof |
| US4761406A (en) | 1985-06-06 | 1988-08-02 | The Procter & Gamble Company | Regimen for treating osteoporosis |
| WO1990009441A1 (en) | 1989-02-01 | 1990-08-23 | The General Hospital Corporation | Herpes simplex virus type i expression vector |
| ATE174058T1 (de) | 1989-11-06 | 1998-12-15 | Cell Genesys Inc | Herstellung von proteinen mittels homologer rekombination |
| IT1238348B (it) | 1989-11-16 | 1993-07-13 | Processo per la preparazione di costrutti genetici per l'espressione del fattore di crescita nervoso in cellule eucariote. | |
| US5266490A (en) | 1991-03-28 | 1993-11-30 | Regeneron Pharmaceuticals, Inc. | Mammalian expression vector |
| JPH0532696A (ja) * | 1990-09-28 | 1993-02-09 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
| NZ245015A (en) | 1991-11-05 | 1995-12-21 | Transkaryotic Therapies Inc | Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production |
| US5434246A (en) * | 1992-03-19 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Parathyroid hormone derivatives |
| US5814603A (en) * | 1992-06-12 | 1998-09-29 | Affymax Technologies N.V. | Compounds with PTH activity |
| US5589452A (en) | 1992-07-14 | 1996-12-31 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
| TW402639B (en) | 1992-12-03 | 2000-08-21 | Transkaryotic Therapies Inc | Protein production and protein delivery |
| US5871486A (en) | 1993-01-21 | 1999-02-16 | Acumed, Inc. | Variable pitch bone screw |
| JPH09500526A (ja) | 1993-06-14 | 1997-01-21 | ベーアーエスエフ アクツィエンゲゼルシャフト | テトラサイクリン反応性プロモーターによる真核細胞の遺伝子発現の厳密な制御 |
| US5763416A (en) | 1994-02-18 | 1998-06-09 | The Regent Of The University Of Michigan | Gene transfer into bone cells and tissues |
| US5656465A (en) | 1994-05-04 | 1997-08-12 | Therion Biologics Corporation | Methods of in vivo gene delivery |
| US5714353A (en) | 1994-05-24 | 1998-02-03 | Research Corporation Technologies, Inc. | Safe vectors for gene therapy |
| US5836905A (en) | 1994-06-20 | 1998-11-17 | Lemelson; Jerome H. | Apparatus and methods for gene therapy |
| JPH09157294A (ja) * | 1995-06-15 | 1997-06-17 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
| CA2178894A1 (en) * | 1995-06-15 | 1996-12-16 | Tsunehiko Fukuda | Parathyroid hormone derivatives and their use |
| US5723577A (en) * | 1995-07-13 | 1998-03-03 | Biomeasure Inc. | Analogs of parathyroid hormone |
| US5917123A (en) | 1997-03-14 | 1999-06-29 | University Of Pittsburgh | Transgenic mice containing a nucleic acid encoding tumor necrosis factor-α under the control of a cardiac specific regulatory region |
| DE69942035D1 (de) * | 1998-11-25 | 2010-04-01 | Gen Hospital Corp | Menschliches parathyroidhormon, modifikationen, herstellung und verwendung |
-
2000
- 2000-02-25 DE DE60040678T patent/DE60040678D1/de not_active Expired - Lifetime
- 2000-02-25 JP JP2001526577A patent/JP4723144B2/ja not_active Expired - Fee Related
- 2000-02-25 WO PCT/US2000/004716 patent/WO2001023427A1/en not_active Ceased
- 2000-02-25 AT AT00910323T patent/ATE412670T1/de not_active IP Right Cessation
- 2000-02-25 EP EP08018788A patent/EP2030986A1/en not_active Withdrawn
- 2000-02-25 EP EP00910323A patent/EP1222208B1/en not_active Expired - Lifetime
- 2000-02-25 ES ES00910323T patent/ES2316354T3/es not_active Expired - Lifetime
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