JP2003510243A5 - - Google Patents
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- Publication number
- JP2003510243A5 JP2003510243A5 JP2000517725A JP2000517725A JP2003510243A5 JP 2003510243 A5 JP2003510243 A5 JP 2003510243A5 JP 2000517725 A JP2000517725 A JP 2000517725A JP 2000517725 A JP2000517725 A JP 2000517725A JP 2003510243 A5 JP2003510243 A5 JP 2003510243A5
- Authority
- JP
- Japan
- Prior art keywords
- iodide
- iodate
- composition according
- anion
- aqueous composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 18
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 6
- 229910052740 iodine Inorganic materials 0.000 claims 6
- 239000011630 iodine Substances 0.000 claims 6
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 claims 6
- FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 claims 6
- 239000003638 chemical reducing agent Substances 0.000 claims 5
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 claims 5
- -1 iodate anion Chemical class 0.000 claims 5
- XMBWDFGMSWQBCA-UHFFFAOYSA-M iodide Chemical compound [I-] XMBWDFGMSWQBCA-UHFFFAOYSA-M 0.000 claims 5
- 239000007800 oxidant agent Substances 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 4
- ICIWUVCWSCSTAQ-UHFFFAOYSA-M iodate Chemical compound [O-]I(=O)=O ICIWUVCWSCSTAQ-UHFFFAOYSA-M 0.000 claims 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- XZXYQEHISUMZAT-UHFFFAOYSA-N 2-[(2-hydroxy-5-methylphenyl)methyl]-4-methylphenol Chemical compound CC1=CC=C(O)C(CC=2C(=CC=C(C)C=2)O)=C1 XZXYQEHISUMZAT-UHFFFAOYSA-N 0.000 claims 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims 2
- 239000004151 Calcium iodate Substances 0.000 claims 2
- UNMYWSMUMWPJLR-UHFFFAOYSA-L Calcium iodide Chemical compound [Ca+2].[I-].[I-] UNMYWSMUMWPJLR-UHFFFAOYSA-L 0.000 claims 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 2
- 229940107816 ammonium iodide Drugs 0.000 claims 2
- UHWJJLGTKIWIJO-UHFFFAOYSA-L calcium iodate Chemical compound [Ca+2].[O-]I(=O)=O.[O-]I(=O)=O UHWJJLGTKIWIJO-UHFFFAOYSA-L 0.000 claims 2
- 235000019390 calcium iodate Nutrition 0.000 claims 2
- 229910001640 calcium iodide Inorganic materials 0.000 claims 2
- 229940046413 calcium iodide Drugs 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 235000010980 cellulose Nutrition 0.000 claims 2
- 239000008121 dextrose Substances 0.000 claims 2
- 210000004051 gastric juice Anatomy 0.000 claims 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims 2
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims 2
- 239000001095 magnesium carbonate Substances 0.000 claims 2
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims 2
- BLQJIBCZHWBKSL-UHFFFAOYSA-L magnesium iodide Chemical compound [Mg+2].[I-].[I-] BLQJIBCZHWBKSL-UHFFFAOYSA-L 0.000 claims 2
- 229910001641 magnesium iodide Inorganic materials 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- NALMPLUMOWIVJC-UHFFFAOYSA-N n,n,4-trimethylbenzeneamine oxide Chemical compound CC1=CC=C([N+](C)(C)[O-])C=C1 NALMPLUMOWIVJC-UHFFFAOYSA-N 0.000 claims 2
- 102000013415 peroxidase activity proteins Human genes 0.000 claims 2
- 108040007629 peroxidase activity proteins Proteins 0.000 claims 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims 2
- JLKDVMWYMMLWTI-UHFFFAOYSA-M potassium iodate Chemical compound [K+].[O-]I(=O)=O JLKDVMWYMMLWTI-UHFFFAOYSA-M 0.000 claims 2
- 239000001230 potassium iodate Substances 0.000 claims 2
- 235000006666 potassium iodate Nutrition 0.000 claims 2
- 229940093930 potassium iodate Drugs 0.000 claims 2
- 229960004839 potassium iodide Drugs 0.000 claims 2
- 239000011697 sodium iodate Substances 0.000 claims 2
- 235000015281 sodium iodate Nutrition 0.000 claims 2
- 229940032753 sodium iodate Drugs 0.000 claims 2
- 235000009518 sodium iodide Nutrition 0.000 claims 2
- 229940083599 sodium iodide Drugs 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 1
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- 244000068988 Glycine max Species 0.000 claims 1
- 235000010469 Glycine max Nutrition 0.000 claims 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 claims 1
- 102100038609 Lactoperoxidase Human genes 0.000 claims 1
- 108010023244 Lactoperoxidase Proteins 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- 239000005913 Maltodextrin Substances 0.000 claims 1
- 229920002774 Maltodextrin Polymers 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- 102000003896 Myeloperoxidases Human genes 0.000 claims 1
- 108090000235 Myeloperoxidases Proteins 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 235000021355 Stearic acid Nutrition 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- VJHCJDRQFCCTHL-UHFFFAOYSA-N acetic acid 2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)=O.OCC(O)C(O)C(O)C(O)C=O VJHCJDRQFCCTHL-UHFFFAOYSA-N 0.000 claims 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims 1
- 239000004327 boric acid Substances 0.000 claims 1
- 229910000019 calcium carbonate Inorganic materials 0.000 claims 1
- 239000001506 calcium phosphate Substances 0.000 claims 1
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 1
- 235000011010 calcium phosphates Nutrition 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 1
- 229940105329 carboxymethylcellulose Drugs 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229960005168 croscarmellose Drugs 0.000 claims 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 239000008172 hydrogenated vegetable oil Substances 0.000 claims 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 229940057428 lactoperoxidase Drugs 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 229940035034 maltodextrin Drugs 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 231100000252 nontoxic Toxicity 0.000 claims 1
- 230000003000 nontoxic effect Effects 0.000 claims 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims 1
- 229940049964 oleate Drugs 0.000 claims 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229910000027 potassium carbonate Inorganic materials 0.000 claims 1
- 229910000160 potassium phosphate Inorganic materials 0.000 claims 1
- 235000011009 potassium phosphates Nutrition 0.000 claims 1
- 238000006479 redox reaction Methods 0.000 claims 1
- 229910000029 sodium carbonate Inorganic materials 0.000 claims 1
- 239000001488 sodium phosphate Substances 0.000 claims 1
- 229910000162 sodium phosphate Inorganic materials 0.000 claims 1
- 235000011008 sodium phosphates Nutrition 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000008117 stearic acid Substances 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 125000000185 sucrose group Chemical group 0.000 claims 1
- 239000000454 talc Substances 0.000 claims 1
- 229910052623 talc Inorganic materials 0.000 claims 1
- 235000012222 talc Nutrition 0.000 claims 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US960149 | 1997-10-29 | ||
| US08/960,149 US5885592A (en) | 1997-10-29 | 1997-10-29 | Methods and pharmaceutical compositions for oral delivery of molecular iodine |
| PCT/US1998/022720 WO1999021567A1 (en) | 1997-10-29 | 1998-10-27 | Pharmaceutical compositions for oral administration of molecular iodine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003510243A JP2003510243A (ja) | 2003-03-18 |
| JP2003510243A5 true JP2003510243A5 (https=) | 2005-05-26 |
| JP4187410B2 JP4187410B2 (ja) | 2008-11-26 |
Family
ID=25502851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000517725A Expired - Fee Related JP4187410B2 (ja) | 1997-10-29 | 1998-10-27 | 分子ヨウ素経口投与のための方法および医薬組成物 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5885592A (https=) |
| EP (1) | EP1024815B1 (https=) |
| JP (1) | JP4187410B2 (https=) |
| KR (1) | KR100412219B1 (https=) |
| CN (1) | CN1150904C (https=) |
| AT (1) | ATE231725T1 (https=) |
| AU (1) | AU750627B2 (https=) |
| BR (1) | BR9812588A (https=) |
| CA (1) | CA2301503C (https=) |
| DE (1) | DE69811105T2 (https=) |
| DK (1) | DK1024815T3 (https=) |
| ES (1) | ES2191973T3 (https=) |
| IL (1) | IL134778A0 (https=) |
| NO (1) | NO20001673L (https=) |
| PT (1) | PT1024815E (https=) |
| RU (1) | RU2213564C2 (https=) |
| WO (1) | WO1999021567A1 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6248335B1 (en) * | 1997-10-29 | 2001-06-19 | Symbollon Corporation | Stabilized oral pharmaceutical composition containing iodide and iodate and method |
| WO1999034809A1 (en) * | 1998-01-06 | 1999-07-15 | Fujisawa Pharmaceutical Co., Ltd. | Solid iodophor preparations and process for producing the same |
| KR20010083057A (ko) | 1998-06-19 | 2001-08-31 | 추후제출 | 항-감염 및 피임성을 갖는 의료 장치 |
| US6154672A (en) * | 1998-06-22 | 2000-11-28 | Pacesetter, Inc. | Method and apparatus for improving the probability of success of defibrillation shocks |
| GB2395901A (en) * | 1999-02-26 | 2004-06-09 | Symbollon Corp | Stabilised tablets containing iodide and iodate |
| ATE320831T1 (de) * | 2000-10-06 | 2006-04-15 | Dmg Italia Srl | Immunotrophische preparation zur behandlung von tonsilläre hypertrophie |
| RU2201229C1 (ru) * | 2002-03-26 | 2003-03-27 | Миронов Владимир Андреевич | Способ оздоровления организма |
| US8501223B2 (en) * | 2003-06-20 | 2013-08-06 | Hill's Pet Nutrition, Inc. | Methods for dietary management of cats to avoid hyperthyroidism |
| CN101416685A (zh) * | 2003-06-20 | 2009-04-29 | 希尔氏宠物营养品公司 | 用于预防猫的甲状腺机能亢进的方法和含有有限碘的组合物 |
| AU2007207991B2 (en) * | 2006-01-26 | 2011-08-04 | Hill's Pet Nutrition, Inc. | Methods and compositions for treating feline hyperthyroidism |
| AU2007249806B2 (en) * | 2006-05-12 | 2011-07-07 | Hill's Pet Nutrition, Inc. | Compositions and methods for preventing or treating chronic renal failure in felines with hyperthyroidism |
| US8303994B2 (en) * | 2006-06-22 | 2012-11-06 | Jack Howard Kessler | Method for the eradication of pathogens including S. aureus and antibiotic resistant microbes from the upper respiratory tract of mammals and for inhibiting the activation of immune cells |
| CN101511205A (zh) * | 2006-07-03 | 2009-08-19 | 希尔氏宠物营养品公司 | 用于在甲状腺机能亢进的猫科动物中预防或治疗心血管疾病的组合物和方法 |
| US8021610B2 (en) * | 2006-09-07 | 2011-09-20 | Biolargo Life Technologies, Inc. | Systems providing antimicrobial activity to an environment |
| US7867510B2 (en) * | 2006-09-07 | 2011-01-11 | BioLargo Life Technologies, Inc | Material having antimicrobial activity when wet |
| US7943158B2 (en) * | 2006-09-07 | 2011-05-17 | BioLargo Life Technologies, Inc | Absorbent systems providing antimicrobial activity |
| US20080063560A1 (en) * | 2006-09-07 | 2008-03-13 | Biolargo Life Technologies, Incorporated | Ground treatment for reducing microbial content |
| US8226964B2 (en) * | 2006-09-07 | 2012-07-24 | Biolargo Life Technologies, Inc. | Systems and methods for cleaning liquid carriers related applications data |
| US9414601B2 (en) * | 2006-09-07 | 2016-08-16 | Biolargo Life Technologies, Incorporated | Material having antimicrobial activity when wet |
| US8257749B2 (en) * | 2007-02-08 | 2012-09-04 | Biolargo Life Technologies, Incorporated | Systems providing at least pesticidal activity |
| WO2009087647A1 (en) * | 2008-01-07 | 2009-07-16 | Council Of Scientific & Industrial Research | A stabilized iodine-water concentrate formulation useful for protection against iodine deficiency disorders |
| MX340005B (es) * | 2010-04-23 | 2016-05-18 | Univ Nac Autónoma De México | Composicion de yodo molecular de uso humano para la prevencion y tratamiento de patologias prostaticas. |
| EA021496B1 (ru) * | 2011-05-16 | 2015-06-30 | Шокан Сабирханович БЕГАЛИЕВ | Лекарственный препарат, обладающий противовирусным и антибактериальным действием |
| CN102697804B (zh) * | 2012-06-07 | 2014-02-12 | 维尔信科技（潍坊）有限公司 | 一种固态分子碘消毒制剂及其制备方法 |
| US10034899B2 (en) * | 2013-11-27 | 2018-07-31 | BioPharmX, Inc. | Solid oral dosage form for breast symptoms |
| KR102304113B1 (ko) * | 2014-02-10 | 2021-09-24 | 프레드 헛친슨 켄서 리서치 센터 | 심장마비 및 허혈성 손상의 할로겐 치료 |
| JP2017517484A (ja) | 2014-03-31 | 2017-06-29 | イオテック インターナショナル， インコーポレイテッド | 非錯体化ヨウ素の安定な組成物及び使用方法 |
| EA031907B1 (ru) * | 2016-03-11 | 2019-03-29 | Тимур Хусаинович Измайлов | Шашка иодная дымовая |
| WO2017185060A1 (en) | 2016-04-21 | 2017-10-26 | BioPharmX, Inc. | Oral iodine dosage form |
| JP7516046B2 (ja) | 2016-07-21 | 2024-07-16 | アイ２ピュア・コーポレーション | エモリエント性の局所消毒剤 |
| CN106727683A (zh) * | 2016-12-23 | 2017-05-31 | 刘海涛 | 一种药物制剂在制备治疗幽门螺杆菌感染性疾病的药物中的应用 |
| TW202203900A (zh) * | 2020-03-31 | 2022-02-01 | 越南商泰明製藥股份有限公司 | 用於治療癌症、子宮內膜異位症以及癌症或子宮內膜異位症患者的疼痛之二異丙胺化合物以及碘 |
| CN116367845A (zh) | 2020-08-13 | 2023-06-30 | I2普乐公司 | 高浓度分子碘组合物，药物制剂，制备和用途 |
| CN116916939A (zh) * | 2020-12-12 | 2023-10-20 | Io医药股份有限公司 | 碘递送化合物 |
| WO2024201560A1 (en) * | 2023-03-24 | 2024-10-03 | Me.Link Co., Ltd. | Iodine containing colloidal liquid composition |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2540170C3 (de) * | 1975-09-10 | 1979-01-18 | Basf Ag, 6700 Ludwigshafen | Verwendung von in organischer Lösung hergestelltem Polyvinylpyrrolidon zur Herstellung von stabilen wäßrigen PoIyvinylpyrrolidon-Jod-Lösungen |
| US4259322A (en) * | 1978-03-20 | 1981-03-31 | Helong Lim | Method of treatment of tuberculosis |
| US4187294A (en) * | 1978-07-06 | 1980-02-05 | Nihon Nousan Kougyou Co., Ltd. | Method for producing eggs containing a high amount of iodinated amino acids |
| JPS5663919A (en) * | 1979-10-29 | 1981-05-30 | Nippon Nousan Kogyo Kk | Remedial composition for diabetes |
| JPS57140723A (en) * | 1981-02-25 | 1982-08-31 | Nippon Nousan Kogyo Kk | Preventing composition for hyperlipemia due to neutral fat |
| US5589198A (en) * | 1985-07-31 | 1996-12-31 | 943038 Ontario, Inc. | Treatment of iodine deficiency diseases |
| US4816255A (en) * | 1985-07-31 | 1989-03-28 | Ghent William R | Treatment of iodine deficiency breast syndrome |
| US5250304A (en) * | 1985-07-31 | 1993-10-05 | Ghent William R | Treatment of iodine deficiency diseases |
| US5171582A (en) * | 1985-07-31 | 1992-12-15 | Ghent William R | Treatment of iodine deficiency diseases |
| US4849237A (en) * | 1987-10-30 | 1989-07-18 | Hurst William D | Method for sanitizing poultry carcasses in a poultry processing plant utilizing ozonated water |
| US5629024A (en) * | 1994-08-22 | 1997-05-13 | Symbollon Corporation | Method of forming an iodine based germicide composition |
-
1997
- 1997-10-29 US US08/960,149 patent/US5885592A/en not_active Expired - Lifetime
-
1998
- 1998-10-21 IL IL13477898A patent/IL134778A0/xx not_active IP Right Cessation
- 1998-10-27 ES ES98954002T patent/ES2191973T3/es not_active Expired - Lifetime
- 1998-10-27 DE DE69811105T patent/DE69811105T2/de not_active Expired - Lifetime
- 1998-10-27 CA CA002301503A patent/CA2301503C/en not_active Expired - Fee Related
- 1998-10-27 JP JP2000517725A patent/JP4187410B2/ja not_active Expired - Fee Related
- 1998-10-27 CN CNB988097648A patent/CN1150904C/zh not_active Expired - Fee Related
- 1998-10-27 AT AT98954002T patent/ATE231725T1/de not_active IP Right Cessation
- 1998-10-27 PT PT98954002T patent/PT1024815E/pt unknown
- 1998-10-27 EP EP98954002A patent/EP1024815B1/en not_active Expired - Lifetime
- 1998-10-27 WO PCT/US1998/022720 patent/WO1999021567A1/en not_active Ceased
- 1998-10-27 BR BR9812588-5A patent/BR9812588A/pt not_active Application Discontinuation
- 1998-10-27 AU AU11227/99A patent/AU750627B2/en not_active Ceased
- 1998-10-27 RU RU2000107852/14A patent/RU2213564C2/ru not_active IP Right Cessation
- 1998-10-27 DK DK98954002T patent/DK1024815T3/da active
- 1998-10-27 KR KR10-2000-7003542A patent/KR100412219B1/ko not_active Expired - Fee Related
-
2000
- 2000-03-31 NO NO20001673A patent/NO20001673L/no not_active Application Discontinuation
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