TR200200710T2 - İlacın nahoş tadını önleyecek şekilde üretilmiş farmasötik sıvı terkipler. - Google Patents

İlacın nahoş tadını önleyecek şekilde üretilmiş farmasötik sıvı terkipler.

Info

Publication number
TR200200710T2
TR200200710T2 TR2002/00710T TR200200710T TR200200710T2 TR 200200710 T2 TR200200710 T2 TR 200200710T2 TR 2002/00710 T TR2002/00710 T TR 2002/00710T TR 200200710 T TR200200710 T TR 200200710T TR 200200710 T2 TR200200710 T2 TR 200200710T2
Authority
TR
Turkey
Prior art keywords
drug
prevent
mae
liquid compositions
unpleasant taste
Prior art date
Application number
TR2002/00710T
Other languages
English (en)
Inventor
Yu Danny
Roche Edward
Original Assignee
Ortho-Mcneil Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical, Inc. filed Critical Ortho-Mcneil Pharmaceutical, Inc.
Publication of TR200200710T2 publication Critical patent/TR200200710T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Bir sulu vasita madde içinde (a) dimetilaminoetil metakrilat ve nötr metakrilik asit esteri (MM/MAE) ve(b) bir selüloz esterinin bir polimer harmanindan, bir tad gizleyici etkili miktar ile bir farmasötik açidan kabul edilebilir aktif tibbi maddeyi içeren, agizdan tatbikat için bir sivi bilesim olup, bu sivi bilesimde, selüloz esterinin MM/MAE' ye polimer agirlik orani 40:60 ila 90:10, tercihan 60:40 kadardir. Sivi bilesim, midenin genellikle 1.0-4.0 kadar olan asit pH' larinda çözünür olan, ancak agzin asidik olmayan pH' larinda nispeten çözünmeyen bir ''ters enterik kaplama'' yi kullanmaktadir. Kaplamalar, genel olarak sivi dozaj biçimleri durumunda arzu edilebilen, ilacin hizli salinma ve emilmesini saglamaktadirlar.
TR2002/00710T 1999-07-09 2000-06-21 İlacın nahoş tadını önleyecek şekilde üretilmiş farmasötik sıvı terkipler. TR200200710T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14301999P 1999-07-09 1999-07-09

Publications (1)

Publication Number Publication Date
TR200200710T2 true TR200200710T2 (tr) 2002-08-21

Family

ID=22502238

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00710T TR200200710T2 (tr) 1999-07-09 2000-06-21 İlacın nahoş tadını önleyecek şekilde üretilmiş farmasötik sıvı terkipler.

Country Status (25)

Country Link
US (2) US6482823B1 (tr)
EP (1) EP1194153B1 (tr)
JP (1) JP2003504335A (tr)
KR (2) KR20020029668A (tr)
CN (1) CN1174740C (tr)
AR (1) AR027179A1 (tr)
AT (1) ATE265852T1 (tr)
AU (1) AU773555B2 (tr)
BR (1) BR0012326A (tr)
CA (1) CA2377916C (tr)
DE (1) DE60010464T2 (tr)
DK (1) DK1194153T3 (tr)
EE (1) EE05147B1 (tr)
ES (1) ES2219360T3 (tr)
HR (1) HRP20020119A2 (tr)
HU (1) HUP0201765A3 (tr)
IL (2) IL147510A0 (tr)
MX (1) MXPA02000331A (tr)
NO (1) NO20020086L (tr)
NZ (1) NZ516486A (tr)
PL (1) PL197812B1 (tr)
PT (1) PT1194153E (tr)
SK (1) SK322002A3 (tr)
TR (1) TR200200710T2 (tr)
WO (1) WO2001003698A1 (tr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001080826A2 (en) * 2000-04-20 2001-11-01 Bristol-Myers Squibb Company Taste masking coating composition
CA2440412A1 (en) * 2001-03-05 2002-09-19 Ortho-Mcneil Pharmaceutical, Inc. Taste masked liquid pharmaceutical compositions
US20040013737A1 (en) * 2002-07-19 2004-01-22 Philippe Becourt Taste masked oral composition of telithromycin
WO2004013047A2 (en) * 2002-08-02 2004-02-12 Eggs In The Pipeline, Llc. System for adding consumable enhancing additives to drinking water
US20080020096A1 (en) * 2003-08-01 2008-01-24 Blum Bradley J System for Adding Consumable Enhancing Additives to Drinking Water
WO2005025622A1 (ja) * 2003-09-12 2005-03-24 Ryukakusan Co. Ltd. 苦みマスキング粒状ゼリー飲料
US7713482B2 (en) 2003-12-18 2010-05-11 The Clorox Company Control scheme for enhanced filtered water systems
US7378015B2 (en) * 2003-12-18 2008-05-27 The Clorox Company Filtered water enhancements
ATE378042T1 (de) * 2004-04-12 2007-11-15 Pfizer Prod Inc Arzneiimittel mit verdecktem geschmack in aufbrechenden multipartikeln
JP2006232789A (ja) * 2005-02-28 2006-09-07 Sawai Pharmaceutical Co Ltd 経口製剤用組成物及びその製造方法
US20060216355A1 (en) * 2005-03-28 2006-09-28 Donald Spector Encapsulated pharmaceuticals in a medium having non-encapsulated flavoring agents
US8247018B2 (en) * 2005-06-20 2012-08-21 Authentiform Technologies, Llc Methods for quality control
WO2007002016A2 (en) * 2005-06-20 2007-01-04 Johnson & Johnson Systems and methods for product authentication
US7874489B2 (en) * 2005-06-20 2011-01-25 Authentiform Technologies, Llc Product authentication
US7973022B2 (en) * 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
US20070197469A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V Fluoroquinolone carboxylic acid salt compositions
EP2091519B1 (en) 2006-11-30 2015-06-24 Bend Research, Inc Multiparticulates of spray-coated drug and polymer on a meltable core
US20110038933A1 (en) * 2008-05-06 2011-02-17 Dexcell Ltd. Stable benzimidazole formulation
CN101618217B (zh) * 2009-07-27 2011-12-28 洛阳君山制药有限公司 一种安胃片的包衣方法
KR101636958B1 (ko) * 2009-09-11 2016-07-06 주식회사 대웅제약 우루소데옥시콜린산-합성하이드로탈사이트-유드라짓 혼성체, 이를 함유하는 약학 조성물 및 그 제조방법
EP2509631A4 (en) * 2009-12-10 2014-04-02 Monosol Rx Llc PH-SENSITIVE COMPOUNDS FOR MASKING THE TASTE OF ORAL STRIPS IN THE FORM OF THIN FILM
US9629920B2 (en) 2009-12-18 2017-04-25 Exodos Life Sciences Limited Partnership Methods and compositions for stable liquid drug formulations
EP2915098A4 (en) 2012-10-30 2016-07-06 Certirx Corp PRODUCT, IMAGE, OR DOCUMENT AUTHENTICATION AND VERIFICATION AND OBJECT IDENTIFICATION
WO2014144661A1 (en) 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Compny Rapidly dispersible dosage form of topiramate
ES2761265T3 (es) 2013-03-15 2020-05-19 Aprecia Pharmaceuticals LLC Forma de dosificación de oxcarbazepina rápidamente dispersable
CN117599029A (zh) 2016-03-17 2024-02-27 硫创治疗公司 用于控制释放半胱胺和系统治疗半胱胺敏感性病症的组合物
KR102088315B1 (ko) 2017-10-23 2020-03-13 주식회사 웅진릴리에뜨 장용성 캡슐의 이취 마스킹 방법 및 이를 이용한 이취의 마스킹 처리가 이루어진 장용성 캡슐
CN111629714A (zh) * 2018-01-22 2020-09-04 强生消费者公司 打孔胶囊
EP3883546A1 (en) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability
CN117503701A (zh) * 2023-12-08 2024-02-06 斯坦德医药研发(江苏)有限公司 左氧氟沙星口服混悬液制剂及制剂制造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62226926A (ja) 1986-03-27 1987-10-05 Teisan Seiyaku Kk 持続性複合顆粒剤
US5065094A (en) 1990-08-07 1991-11-12 Seagate Technology, Inc. Two terminal magnetoresistive sensor having DC blocking capacitor
FR2665635A1 (fr) 1990-08-10 1992-02-14 Merck Sharp & Dohme Composition pharmaceutique fluide a base d'un complexe metallique et son procede de preparation.
CA2068402C (en) * 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5599556A (en) 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
DE4200821A1 (de) 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
FR2694751B1 (fr) * 1992-08-14 1994-11-25 Bouchara Sa Nouveaux dérivés sulfonamides, leurs procédés de préparation et les compositions en renfermant.
US5614222A (en) * 1994-10-25 1997-03-25 Kaplan; Milton R. Stable aqueous drug suspensions and methods for preparation thereof

Also Published As

Publication number Publication date
DK1194153T3 (da) 2004-08-02
KR20020029668A (ko) 2002-04-19
AU5880200A (en) 2001-01-30
ES2219360T3 (es) 2004-12-01
IL147510A (en) 2007-06-03
AR027179A1 (es) 2003-03-19
US20030064107A1 (en) 2003-04-03
MXPA02000331A (es) 2002-06-21
ATE265852T1 (de) 2004-05-15
US6586012B2 (en) 2003-07-01
CA2377916A1 (en) 2001-01-18
SK322002A3 (en) 2003-02-04
NZ516486A (en) 2003-10-31
IL147510A0 (en) 2002-08-14
JP2003504335A (ja) 2003-02-04
US6482823B1 (en) 2002-11-19
EE200200012A (et) 2003-02-17
WO2001003698A1 (en) 2001-01-18
DE60010464D1 (de) 2004-06-09
HRP20020119A2 (en) 2003-12-31
EP1194153A1 (en) 2002-04-10
CN1174740C (zh) 2004-11-10
PL197812B1 (pl) 2008-04-30
KR100675809B1 (ko) 2007-02-01
BR0012326A (pt) 2002-03-12
EP1194153B1 (en) 2004-05-06
AU773555B2 (en) 2004-05-27
NO20020086L (no) 2002-03-05
EE05147B1 (et) 2009-04-15
HUP0201765A3 (en) 2004-05-28
HUP0201765A2 (hu) 2002-11-28
KR20020031382A (ko) 2002-05-01
NO20020086D0 (no) 2002-01-08
CN1360504A (zh) 2002-07-24
DE60010464T2 (de) 2005-05-12
CA2377916C (en) 2008-03-11
PT1194153E (pt) 2004-09-30
PL352761A1 (en) 2003-09-08

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