JP2003510050A5 - - Google Patents
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- Publication number
- JP2003510050A5 JP2003510050A5 JP2001525362A JP2001525362A JP2003510050A5 JP 2003510050 A5 JP2003510050 A5 JP 2003510050A5 JP 2001525362 A JP2001525362 A JP 2001525362A JP 2001525362 A JP2001525362 A JP 2001525362A JP 2003510050 A5 JP2003510050 A5 JP 2003510050A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- vaccine
- seq
- nucleic acid
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 description 24
- 102000004196 processed proteins & peptides Human genes 0.000 description 24
- 108090000765 processed proteins & peptides Proteins 0.000 description 24
- 229960005486 vaccine Drugs 0.000 description 17
- 102000039446 nucleic acids Human genes 0.000 description 12
- 108020004707 nucleic acids Proteins 0.000 description 12
- 150000007523 nucleic acids Chemical class 0.000 description 12
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 11
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- 230000005847 immunogenicity Effects 0.000 description 5
- 208000007190 Chlamydia Infections Diseases 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000013613 expression plasmid Substances 0.000 description 1
- 239000013604 expression vector Substances 0.000 description 1
- 108020001507 fusion proteins Proteins 0.000 description 1
- 102000037865 fusion proteins Human genes 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15465299P | 1999-09-20 | 1999-09-20 | |
| US60/154,652 | 1999-09-20 | ||
| PCT/CA2000/001088 WO2001021804A1 (en) | 1999-09-20 | 2000-09-15 | Chlamydia antigens and corresponding dna fragments and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003510050A JP2003510050A (ja) | 2003-03-18 |
| JP2003510050A5 true JP2003510050A5 (https=) | 2007-11-08 |
| JP4667694B2 JP4667694B2 (ja) | 2011-04-13 |
Family
ID=22552195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001525362A Expired - Fee Related JP4667694B2 (ja) | 1999-09-20 | 2000-09-15 | クラミジア抗原および対応するdna断片ならびにその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7314869B2 (https=) |
| EP (1) | EP1220925B8 (https=) |
| JP (1) | JP4667694B2 (https=) |
| AT (1) | ATE384793T1 (https=) |
| AU (1) | AU783547B2 (https=) |
| CA (1) | CA2385325C (https=) |
| DE (1) | DE60037900T2 (https=) |
| NZ (1) | NZ517952A (https=) |
| WO (1) | WO2001021804A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6686339B1 (en) | 1998-08-20 | 2004-02-03 | Aventis Pasteur Limited | Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia |
| EP1105489A1 (en) | 1998-08-20 | 2001-06-13 | Aventis Pasteur Limited | Nucleic acid molecules encoding pomp91a protein of chlamydia |
| WO2000011181A1 (en) | 1998-08-20 | 2000-03-02 | Connaught Laboratories Limited | NUCLEIC ACID MOLECULES ENCODING INCLUSION MEMBRANE PROTEIN C OF $i(CHLAMYDIA) |
| US6649370B1 (en) | 1998-10-28 | 2003-11-18 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6607730B1 (en) | 1998-11-02 | 2003-08-19 | Aventis Pasteur Limited/Aventis Pasteur Limitee | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| CA2353107A1 (en) | 1998-12-01 | 2000-06-08 | Andrew D. Murdin | Chlamydia antigens and corresponding dna fragments and uses thereof |
| EP1169465B1 (en) * | 1998-12-04 | 2006-03-01 | University Of Manitoba | Two-step immunization procedure against chlamydia infection |
| US20020061848A1 (en) | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| JP2002531129A (ja) | 1998-12-08 | 2002-09-24 | コリクサ コーポレイション | クラミジア感染の処置および診断のための化合物および方法 |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| US7297341B1 (en) | 1998-12-23 | 2007-11-20 | Sanofi Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6808713B1 (en) | 1998-12-28 | 2004-10-26 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| JP2002541766A (ja) | 1998-12-28 | 2002-12-10 | アベンティス、パストゥール、リミテッド | クラミジア抗原および対応するdna断片ならびにその使用 |
| GB9902555D0 (en) | 1999-02-05 | 1999-03-24 | Neutec Pharma Plc | Medicament |
| MXPA01009256A (es) | 1999-03-12 | 2003-07-14 | Aventis Pasteur | Antigenos de chlamydia y fragmentos de acido desoxirribonucleico correspondientes y usos de los mismos. |
| DE60036698T2 (de) | 1999-05-03 | 2008-07-24 | Sanofi Pasteur Ltd., Toronto | Chlamydia-antigene und entsprechende dna-fragmente und deren verwendungen |
| NZ517952A (en) | 1999-09-20 | 2004-01-30 | Aventis Pasteur | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6632663B1 (en) | 1999-09-22 | 2003-10-14 | Aventis Pasteur Limited | DNA immunization against chlamydia infection |
| EP1240331B1 (en) | 1999-12-22 | 2010-04-07 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| WO2001081379A2 (en) | 2000-04-21 | 2001-11-01 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US6919187B2 (en) * | 2000-04-21 | 2005-07-19 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| AU2001258105A1 (en) | 2000-05-08 | 2001-11-20 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| JP2004502415A (ja) | 2000-07-03 | 2004-01-29 | カイロン エセ.ピー.アー. | Chlamydiapneumoniaeに対する免疫化 |
| EP1687430A4 (en) * | 2003-11-21 | 2007-05-02 | Sanofi Pasteur Ltd | IMMUNIZATION AGAINST CHLAMYDIA INFECTION |
| US8568732B2 (en) | 2009-03-06 | 2013-10-29 | Novartis Ag | Chlamydia antigens |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE312920T1 (de) | 1996-07-12 | 2005-12-15 | Dna immunisierung gegen chlamydia infektion | |
| US6579854B1 (en) * | 1996-08-14 | 2003-06-17 | Vanderbilt University | Diagnosis and management of infection caused by chlamydia |
| JP4160640B2 (ja) * | 1997-06-23 | 2008-10-01 | スヴェンド バークランド | クラミジア・ニューモニエ由来の表面露出タンパク質 |
| DE69841894D1 (de) * | 1997-11-21 | 2010-10-21 | Merck Serono Biodevelopment Sa | Äusseres Membranpolypeptid von Chlamydia pneumoniae sowie Fragmente davon und deren Verwendung, insbesondere zur Diagnose, Prävention und Behandlung einer Infektion |
| JP2002536958A (ja) * | 1997-11-21 | 2002-11-05 | ジェンセット | Chlamydiapneumoniaeゲノム配列およびポリペプチド、それらのフラグメント、ならびに特に感染症の診断、予防および治療のためのそれらの使用 |
| EP2218731A1 (en) | 1997-11-28 | 2010-08-18 | Merck Serono Biodevelopment | Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection |
| US6541011B2 (en) * | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| WO2000011181A1 (en) * | 1998-08-20 | 2000-03-02 | Connaught Laboratories Limited | NUCLEIC ACID MOLECULES ENCODING INCLUSION MEMBRANE PROTEIN C OF $i(CHLAMYDIA) |
| US6693087B1 (en) * | 1998-08-20 | 2004-02-17 | Aventis Pasteur Limited | Nucleic acid molecules encoding POMP91A protein of Chlamydia |
| MXPA01004291A (es) | 1998-10-28 | 2003-06-09 | Aventis Pasteur | Antigenos de chlamydia y fragmentos de acido desoxirribonucleico correspondientes y usos de los mismos. |
| US6822071B1 (en) * | 1998-11-12 | 2004-11-23 | The Regents Of The University Of California | Polypeptides from Chlamydia pneumoniae and their use in the diagnosis, prevention and treatment of disease |
| CA2350775A1 (en) | 1998-11-12 | 2000-05-18 | The Regents Of The University Of California | Chlamydia pneumoniae genome sequence |
| CA2353107A1 (en) * | 1998-12-01 | 2000-06-08 | Andrew D. Murdin | Chlamydia antigens and corresponding dna fragments and uses thereof |
| JP2002531129A (ja) | 1998-12-08 | 2002-09-24 | コリクサ コーポレイション | クラミジア感染の処置および診断のための化合物および方法 |
| US6565856B1 (en) | 1998-12-08 | 2003-05-20 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20020061848A1 (en) | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| US6808713B1 (en) * | 1998-12-28 | 2004-10-26 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| GB9902555D0 (en) | 1999-02-05 | 1999-03-24 | Neutec Pharma Plc | Medicament |
| DE60036698T2 (de) | 1999-05-03 | 2008-07-24 | Sanofi Pasteur Ltd., Toronto | Chlamydia-antigene und entsprechende dna-fragmente und deren verwendungen |
| NZ517952A (en) | 1999-09-20 | 2004-01-30 | Aventis Pasteur | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6632663B1 (en) | 1999-09-22 | 2003-10-14 | Aventis Pasteur Limited | DNA immunization against chlamydia infection |
| AU2138501A (en) * | 1999-12-22 | 2001-07-03 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| EP1240331B1 (en) | 1999-12-22 | 2010-04-07 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US20030100706A1 (en) * | 2000-04-04 | 2003-05-29 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020071831A1 (en) * | 2000-04-04 | 2002-06-13 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020082402A1 (en) * | 2000-04-04 | 2002-06-27 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020132994A1 (en) * | 2000-04-04 | 2002-09-19 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020094965A1 (en) * | 2000-04-04 | 2002-07-18 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| WO2001081379A2 (en) | 2000-04-21 | 2001-11-01 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| AU2001258105A1 (en) | 2000-05-08 | 2001-11-20 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US20040254130A1 (en) * | 2000-05-08 | 2004-12-16 | Murdin Andrew D | Chlamydia antigens and corresponding dna fragments and uses thereof |
| JP2004502415A (ja) | 2000-07-03 | 2004-01-29 | カイロン エセ.ピー.アー. | Chlamydiapneumoniaeに対する免疫化 |
-
2000
- 2000-09-15 NZ NZ517952A patent/NZ517952A/en not_active IP Right Cessation
- 2000-09-15 AU AU73985/00A patent/AU783547B2/en not_active Ceased
- 2000-09-15 CA CA2385325A patent/CA2385325C/en not_active Expired - Fee Related
- 2000-09-15 JP JP2001525362A patent/JP4667694B2/ja not_active Expired - Fee Related
- 2000-09-15 EP EP00962125A patent/EP1220925B8/en not_active Expired - Lifetime
- 2000-09-15 DE DE60037900T patent/DE60037900T2/de not_active Expired - Lifetime
- 2000-09-15 AT AT00962125T patent/ATE384793T1/de active
- 2000-09-15 WO PCT/CA2000/001088 patent/WO2001021804A1/en not_active Ceased
-
2003
- 2003-12-29 US US10/746,251 patent/US7314869B2/en not_active Expired - Fee Related
-
2005
- 2005-06-02 US US11/142,306 patent/US7662391B2/en not_active Expired - Fee Related
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