JP2003509040A5 - - Google Patents
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- Publication number
- JP2003509040A5 JP2003509040A5 JP2001523623A JP2001523623A JP2003509040A5 JP 2003509040 A5 JP2003509040 A5 JP 2003509040A5 JP 2001523623 A JP2001523623 A JP 2001523623A JP 2001523623 A JP2001523623 A JP 2001523623A JP 2003509040 A5 JP2003509040 A5 JP 2003509040A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- milk
- protein
- secreted
- transgenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108020001507 fusion proteins Proteins 0.000 claims 21
- 102000037865 fusion proteins Human genes 0.000 claims 21
- 238000000034 method Methods 0.000 claims 14
- 108090000623 proteins and genes Proteins 0.000 claims 11
- 230000009261 transgenic effect Effects 0.000 claims 11
- 235000013336 milk Nutrition 0.000 claims 10
- 239000008267 milk Substances 0.000 claims 10
- 210000004080 milk Anatomy 0.000 claims 10
- 235000018102 proteins Nutrition 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 241000124008 Mammalia Species 0.000 claims 5
- 241001465754 Metazoa Species 0.000 claims 4
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 4
- 108700019146 Transgenes Proteins 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 108060003951 Immunoglobulin Proteins 0.000 claims 3
- 210000002919 epithelial cell Anatomy 0.000 claims 3
- 102000018358 immunoglobulin Human genes 0.000 claims 3
- 108010022366 Carcinoembryonic Antigen Proteins 0.000 claims 2
- 102100025475 Carcinoembryonic antigen-related cell adhesion molecule 5 Human genes 0.000 claims 2
- 108091026890 Coding region Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 102000006382 Ribonucleases Human genes 0.000 claims 2
- 108010083644 Ribonucleases Proteins 0.000 claims 2
- 108091036066 Three prime untranslated region Proteins 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 239000012212 insulator Substances 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 230000028327 secretion Effects 0.000 claims 2
- 102100022987 Angiogenin Human genes 0.000 claims 1
- 102000003670 Carboxypeptidase B Human genes 0.000 claims 1
- 108090000087 Carboxypeptidase B Proteins 0.000 claims 1
- 101710112752 Cytotoxin Proteins 0.000 claims 1
- 102000001301 EGF receptor Human genes 0.000 claims 1
- 108060006698 EGF receptor Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000012745 Immunoglobulin Subunits Human genes 0.000 claims 1
- 108010079585 Immunoglobulin Subunits Proteins 0.000 claims 1
- 108010011756 Milk Proteins Proteins 0.000 claims 1
- 108020002230 Pancreatic Ribonuclease Proteins 0.000 claims 1
- 102000005891 Pancreatic ribonuclease Human genes 0.000 claims 1
- 102000007238 Transferrin Receptors Human genes 0.000 claims 1
- 108010033576 Transferrin Receptors Proteins 0.000 claims 1
- 108010072788 angiogenin Proteins 0.000 claims 1
- 231100000599 cytotoxic agent Toxicity 0.000 claims 1
- 239000002619 cytotoxin Substances 0.000 claims 1
- 210000005075 mammary gland Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 101150047061 tag-72 gene Proteins 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39861099A | 1999-09-17 | 1999-09-17 | |
| US09/398,610 | 1999-09-17 | ||
| PCT/US2000/025560 WO2001019846A1 (en) | 1999-09-17 | 2000-09-18 | Transgenically produced fusion proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003509040A JP2003509040A (ja) | 2003-03-11 |
| JP2003509040A5 true JP2003509040A5 (pt) | 2005-09-02 |
Family
ID=23576046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001523623A Withdrawn JP2003509040A (ja) | 1999-09-17 | 2000-09-18 | 遺伝子導入により産生された融合タンパク質 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1220864A4 (pt) |
| JP (1) | JP2003509040A (pt) |
| KR (1) | KR20020073127A (pt) |
| CN (1) | CN1414970A (pt) |
| AU (1) | AU782840B2 (pt) |
| BR (1) | BR0014527A (pt) |
| CA (1) | CA2382725A1 (pt) |
| HU (1) | HUP0500423A2 (pt) |
| IL (1) | IL148550A0 (pt) |
| MX (1) | MXPA02002769A (pt) |
| NO (1) | NO20021275L (pt) |
| NZ (1) | NZ517666A (pt) |
| RU (1) | RU2002110121A (pt) |
| WO (1) | WO2001019846A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800462B2 (en) * | 2001-09-10 | 2004-10-05 | Abgenomics Corporation | Production of recombinant proteins in vivo and use for generating antibodies |
| US20030049694A1 (en) * | 2001-09-10 | 2003-03-13 | Chung-Hsiun Wu | Production of fusion proteins and use for identifying binding molecules |
| KR100603016B1 (ko) * | 2004-07-21 | 2006-07-24 | 황호연 | 라벨용 포장필름의 제조방법, 상기 제조방법으로 제조된라벨용 포장필름 및 상기 포장필름의 사용방법 |
| WO2007122511A2 (en) * | 2006-04-21 | 2007-11-01 | Mab-Factory Gmbh | Antibody-rnase-conjugate |
| KR100952960B1 (ko) * | 2007-12-31 | 2010-04-15 | 전남대학교산학협력단 | 돼지 β-카제인 게놈 ＤＮＡ를 이용하여 생리활성물질을생산하기 위한 넉-인 벡터 및 이를 이용하여생리활성물질을 생산하는 방법 |
| US9150880B2 (en) | 2008-09-25 | 2015-10-06 | Proteovec Holding, L.L.C. | Vectors for production of antibodies |
| US9157097B2 (en) | 2008-09-25 | 2015-10-13 | Proteovec Holding, L.L.C. | Vectors for production of growth hormone |
| WO2010118360A1 (en) | 2009-04-09 | 2010-10-14 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Production of proteins using transposon-based vectors |
| US20120331575A1 (en) * | 2009-11-18 | 2012-12-27 | Agriculture Victoria Services Pty Ltd | Transgenic non-human animals |
| CN102981002B (zh) * | 2012-11-29 | 2014-08-06 | 同昕生物技术（北京）有限公司 | 采用标签蛋白人源化嵌合抗体作为阳性对照物的间接免疫检测方法及试剂盒 |
| CN104862318A (zh) * | 2014-02-25 | 2015-08-26 | 南京杰蒙生物技术有限公司 | 利用转基因动物乳腺生物反应器生产单克隆抗体的方法 |
| AR113430A1 (es) * | 2017-12-22 | 2020-04-29 | Hanmi Pharm Ind Co Ltd | Proteína de fusión enzimática terapéutica que tiene una nueva estructura y su uso |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0832981A1 (en) * | 1987-02-17 | 1998-04-01 | Pharming B.V. | DNA sequences to target proteins to the mammary gland for efficient secretion |
| US5840840A (en) * | 1990-04-17 | 1998-11-24 | The United States Of America As Represented By The Department Of Health And Human Services | Selective RNase cytotoxic reagents |
| US5206161A (en) * | 1991-02-01 | 1993-04-27 | Genentech, Inc. | Human plasma carboxypeptidase B |
| IL111748A0 (en) * | 1993-12-03 | 1995-01-24 | Zeneca Ltd | Proteins |
| GB9406974D0 (en) * | 1994-04-08 | 1994-06-01 | Pharmaceutical Proteins Ltd | Transgenic production |
| US5959171A (en) * | 1994-08-17 | 1999-09-28 | Pharming B.V. | Method for the production of biologically active polypeptides in a mammal's |
| US5880327A (en) * | 1994-09-21 | 1999-03-09 | American National Red Cross | Transgenic mammals expressing human coagulation factor VIII |
| AU701916B2 (en) * | 1994-12-23 | 1999-02-11 | London Biotechnology Limited | Chemical compounds |
| IL116696A (en) * | 1995-01-25 | 1999-08-17 | Bio Technology General Corp | Production of enzymatically active recombinant carboxypeptidase b |
| EP0844885A2 (en) * | 1995-08-16 | 1998-06-03 | Zeneca Limited | Chemical compounds |
| JP2002512502A (ja) * | 1996-10-25 | 2002-04-23 | セル・ジェネシス・インコーポレイテッド | 癌細胞の標的細胞溶解 |
-
2000
- 2000-09-18 MX MXPA02002769A patent/MXPA02002769A/es unknown
- 2000-09-18 RU RU2002110121/13A patent/RU2002110121A/ru not_active Application Discontinuation
- 2000-09-18 KR KR1020027003529A patent/KR20020073127A/ko not_active Application Discontinuation
- 2000-09-18 WO PCT/US2000/025560 patent/WO2001019846A1/en active IP Right Grant
- 2000-09-18 AU AU38832/01A patent/AU782840B2/en not_active Ceased
- 2000-09-18 CN CN00814423A patent/CN1414970A/zh active Pending
- 2000-09-18 HU HU0500423A patent/HUP0500423A2/hu unknown
- 2000-09-18 BR BR0014527-0A patent/BR0014527A/pt not_active Expired - Fee Related
- 2000-09-18 JP JP2001523623A patent/JP2003509040A/ja not_active Withdrawn
- 2000-09-18 EP EP00963586A patent/EP1220864A4/en not_active Withdrawn
- 2000-09-18 CA CA002382725A patent/CA2382725A1/en not_active Abandoned
- 2000-09-18 NZ NZ517666A patent/NZ517666A/en unknown
- 2000-09-18 IL IL14855000A patent/IL148550A0/xx unknown
-
2002
- 2002-03-14 NO NO20021275A patent/NO20021275L/no not_active Application Discontinuation
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