JP2003501344A5 - - Google Patents

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Publication number
JP2003501344A5
JP2003501344A5 JP2000585197A JP2000585197A JP2003501344A5 JP 2003501344 A5 JP2003501344 A5 JP 2003501344A5 JP 2000585197 A JP2000585197 A JP 2000585197A JP 2000585197 A JP2000585197 A JP 2000585197A JP 2003501344 A5 JP2003501344 A5 JP 2003501344A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
venlafaxine
stereoisomer
substantially free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000585197A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003501344A (ja
Filing date
Publication date
Priority claimed from US09/450,691 external-priority patent/US6197828B1/en
Application filed filed Critical
Publication of JP2003501344A publication Critical patent/JP2003501344A/ja
Publication of JP2003501344A5 publication Critical patent/JP2003501344A5/ja
Pending legal-status Critical Current

Links

JP2000585197A 1998-12-01 1999-12-01 （＋）−ベンラファキシン誘導体並びにその製造方法および使用方法 Pending JP2003501344A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11048698P 1998-12-01 1998-12-01
US60/110,486 1998-12-01
US09/450,691 US6197828B1 (en) 1998-12-01 1999-11-30 Derivatives of (+)-venlafaxine and methods of preparing and using the same
US09/450,691 1999-11-30
PCT/US1999/028306 WO2000032555A1 (en) 1998-12-01 1999-12-01 Derivatives of (+)-venlafaxine and methods of preparing and using the same

Publications (2)

Publication Number Publication Date
JP2003501344A JP2003501344A (ja) 2003-01-14
JP2003501344A5 true JP2003501344A5 (https=) 2007-01-25

Family

ID=26808067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000585197A Pending JP2003501344A (ja) 1998-12-01 1999-12-01 （＋）−ベンラファキシン誘導体並びにその製造方法および使用方法

Country Status (5)

Country Link
US (1) US6197828B1 (https=)
EP (1) EP1135358A1 (https=)
JP (1) JP2003501344A (https=)
CA (1) CA2352321A1 (https=)
WO (1) WO2000032555A1 (https=)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
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DE60039132D1 (de) 1999-04-06 2008-07-17 Sepracor Inc O-Desmethylvenlafaxin-Succinat
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WO2000076955A1 (en) * 1999-06-15 2000-12-21 American Home Products Corporation Enantiomers of o-desmethyl venlafaxine
WO2000076956A2 (en) * 1999-06-15 2000-12-21 American Home Products Corporation Enantiomers of n-desmethyl venlafaxine
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US6348494B1 (en) 2000-11-21 2002-02-19 American Home Products Corporation Ethers of o-desmethyl venlafaxine
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SK5762003A3 (en) * 2000-10-19 2003-11-04 Teva Pharma Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
US20020183553A1 (en) 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
EP1864967A1 (en) 2001-02-12 2007-12-12 Wyeth Method for preparing O-desmethyl-venlafaxine
UA80543C2 (en) * 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine
EP1485344A1 (en) 2002-03-28 2004-12-15 Synthon B.V. Venlafaxine besylate
US6696496B2 (en) 2002-03-28 2004-02-24 Synthon Bv Low water-soluble venlafaxine salts
AU2003219117A1 (en) * 2002-03-28 2003-10-13 Synthon B.V. Extended release venlafaxine formulations
US20030190352A1 (en) * 2002-03-28 2003-10-09 Synthon Bv Compositions of venlafaxine base
NZ537142A (en) * 2002-06-10 2008-01-31 Wyeth Corp Novel formate salt of O-desmethyl-venlafaxine
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US20070077301A1 (en) * 2002-12-23 2007-04-05 Meyer Glenn A Venlafaxine osmotic device formulation
AU2003302147A1 (en) * 2002-12-23 2004-07-14 Osmotica Costa Rica Sociedad Anonima Delivery device containing venlafaxine and memantine and use method thereof
DE10350194B4 (de) * 2003-10-28 2005-11-10 Bioplanta Arzneimittel Gmbh Verwendung von Extrakten aus Opuntien zur Behandlung von depressiven Verstimmungen und Erkrankungen
US20050048118A1 (en) * 2003-07-25 2005-03-03 Joan Cucala Escoi Modified release venlafaxine hydrochloride tablets
CA2554559A1 (en) * 2004-02-06 2005-08-25 Wyeth Multiparticulate o-desmethylvenlafaxine salts and uses thereof
US20050226923A1 (en) * 2004-04-07 2005-10-13 Gassert Chad M Venlafaxine compositions in the form of microtablets
WO2005102366A2 (en) * 2004-04-19 2005-11-03 Philip Maxwell Satow Lithium combinations, and uses related thereto
US7776358B2 (en) * 2004-07-22 2010-08-17 Synthon Ip Inc. Extended release venlafaxine besylate tablets
US20060193912A1 (en) * 2005-02-28 2006-08-31 Penwest Pharmaceuticals Co. Controlled release O-desmethylvenlafaxine formulations
CA2614209A1 (en) * 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and o-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
US7687520B2 (en) 2005-07-15 2010-03-30 Wyeth Llc Serotonin and norepinephrine reuptake inhibitors and uses thereof
US7595340B2 (en) 2005-07-15 2009-09-29 Wyeth Serotonin and norepinephrine reuptake inhibitor and uses thereof
HUE027865T2 (en) * 2005-12-01 2016-11-28 Auspex Pharmaceuticals Inc Substituted phenyl ethylamines with serotonergic and / or norepinephrine activity
EP1973866A1 (en) 2005-12-20 2008-10-01 Synthon B.V. Process for making desvenlafaxine
WO2007120923A1 (en) * 2006-04-17 2007-10-25 Teva Pharmaceutical Industries Ltd. Substantially pure o-desmethylvenlafaxine and processes for preparing it
MX2007016179A (es) * 2006-04-17 2008-03-11 Teva Pharma Formas cristalinas de o-desmetilvenlafaxina.
TW200806282A (en) * 2006-05-05 2008-02-01 Wyeth Corp Solid dosage formulations
CN100506784C (zh) * 2006-05-22 2009-07-01 浙江苏泊尔制药有限公司 万拉法新的制备方法
US20090137846A1 (en) * 2006-07-26 2009-05-28 Valerie Niddam-Hildesheim Processes for the synthesis of O-Desmethylvenlafaxine
US20080221356A1 (en) * 2006-07-26 2008-09-11 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
WO2008013993A2 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
US20090062572A1 (en) * 2006-07-26 2009-03-05 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
US20090069601A1 (en) * 2006-07-26 2009-03-12 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
WO2008013995A2 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Tridesmethylvenlafaxine and processes for the synthesis of o-desmethylvenlafaxine
EP2061750A2 (en) * 2006-08-04 2009-05-27 Medichem, S.A. Improved process for synthesizing desvenlafaxine free base and salts or solvates thereof
CA2659295A1 (en) * 2006-08-08 2008-02-14 Generics [Uk] Limited Novel hydrate form of o-desmethyl venlafaxine succinate
IN2009DN05509A (https=) * 2007-03-14 2010-04-30 Teva Pharma
WO2009010990A2 (en) * 2007-07-16 2009-01-22 Matrix Laboratories Limited Process for the preparation of o-desmethylvenlafaxine succinate polymorphic forms
US20100330172A1 (en) * 2007-10-16 2010-12-30 Alphapharm Pty Ltd Controlled-release pharmaceutical formulation
AU2008315740A1 (en) 2007-10-26 2009-04-30 Generics [Uk] Limited Process for preparing O-desmethylvenlafaxine
WO2009070311A2 (en) * 2007-11-26 2009-06-04 Teva Pharmaceutical Industries Ltd. Crystal forms of o-desmethylvenlafaxine fumarate
EP2074993A1 (en) 2007-12-19 2009-07-01 Biovail Laboratories International S.r.l. Venlafaxine-containing film-coated modified-release tablets
WO2009084039A2 (en) * 2007-12-26 2009-07-09 Matrix Laboratories Limited Process for producing 1-[2-(dimethylamino)-1-(4-phenol)ethyl]cyclohexanol
EP2085377A1 (en) * 2008-01-29 2009-08-05 LEK Pharmaceuticals D.D. Novel salts of O-desmethyl-venlafaxine
WO2009151494A1 (en) * 2008-03-06 2009-12-17 Teva Pharmaceutical Industries Ltd. Processes for the preparation of o-desmethylvenlafaxine, free from its dimer impurities
KR100965527B1 (ko) 2008-05-08 2010-06-23 제일약품주식회사 신규(4-(2-(디메틸아미노)-1-(1-하이드록시사이클로헥실)에틸)페녹시)포스페이트 또는 이의 약학적으로 허용가능한 염,이의 제조방법 및 이를 유효성분으로 함유하는 중추신경계질환 예방 및 치료용 조성물
CA2720538A1 (en) * 2008-06-16 2010-01-21 Teva Pharmaceutical Industries Ltd. Solid states of o-desmethylvenlafaxine salts
WO2010062690A1 (en) * 2008-10-30 2010-06-03 Concert Pharmaceuticals Inc. Combination of morphinan compounds and antidepressant for the treatment of pseudobulbar affect, neurological diseases, intractable and chronic pain and brain injury
EP2191822A1 (en) 2008-11-26 2010-06-02 LEK Pharmaceuticals d.d. Controlled release pharmaceutical compositions comprising O-desmethyl-venlafaxine
US20110184067A1 (en) * 2010-01-25 2011-07-28 Intas Pharmaceuticals Ltd. O-desmethylvenlafaxine succinate polymorph & process for preparing thereof
WO2011121452A2 (en) 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate
MX2012010659A (es) 2010-03-31 2013-03-05 Wockhardt Ltd Composicion farmaceutica de liberacion modificada que comprende desvenlafaxina o sus sales.
CZ303249B6 (cs) 2010-04-06 2012-06-20 Zentiva, K.S. Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
CN102249936B (zh) * 2010-05-19 2014-09-17 江苏豪森医药集团有限公司 O-去甲基文拉法辛盐酸盐的水合物及其制备方法
US8933123B2 (en) 2010-10-08 2015-01-13 Cadila Healthcare Limited Polymorphic forms of O-desmethyl-venlafaxine succinate
BR112013025766A2 (pt) 2011-04-12 2016-12-20 Lupin Ltd composições farmacêuticas de liberação modificada de desvenlafaxina
CN104529797A (zh) * 2014-12-05 2015-04-22 南昌市博泽康医药科技有限公司 盐酸文拉法辛手性晶型的制备
MX367362B (es) 2016-06-29 2019-08-16 Alparis Sa De Cv Nuevas formas solidas de desvenlafaxina.

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AU4542893A (en) 1992-06-23 1994-01-24 Sepracor, Inc. Methods and compositions for treating depression and other disorders using optically pure (-) sibutramine
AU4542993A (en) 1992-06-23 1994-01-24 Sepracor, Inc. Methods and compositions for treating depression and other disorders using optically pure (+) sibutramine
TW344661B (en) 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
US5554383A (en) 1995-04-06 1996-09-10 Trustees Of Tufts College Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression

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