JP2003524613A5 - - Google Patents

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Publication number
JP2003524613A5
JP2003524613A5 JP2000585198A JP2000585198A JP2003524613A5 JP 2003524613 A5 JP2003524613 A5 JP 2003524613A5 JP 2000585198 A JP2000585198 A JP 2000585198A JP 2000585198 A JP2000585198 A JP 2000585198A JP 2003524613 A5 JP2003524613 A5 JP 2003524613A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
venlafaxine
acceptable salt
substantially free
stereoisomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000585198A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003524613A (ja
Filing date
Publication date
Priority claimed from US09/450,690 external-priority patent/US6342533B1/en
Application filed filed Critical
Publication of JP2003524613A publication Critical patent/JP2003524613A/ja
Publication of JP2003524613A5 publication Critical patent/JP2003524613A5/ja
Pending legal-status Critical Current

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JP2000585198A 1998-12-01 1999-12-01 (−)−ベンラファキシン誘導体並びにその製造方法および使用方法 Pending JP2003524613A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11048898P 1998-12-01 1998-12-01
US60/110,488 1998-12-01
US09/450,690 1999-11-30
US09/450,690 US6342533B1 (en) 1998-12-01 1999-11-30 Derivatives of (−)-venlafaxine and methods of preparing and using the same
PCT/US1999/028303 WO2000032556A1 (en) 1998-12-01 1999-12-01 Derivatives of (-)-venlafaxine and methods of preparing and using the same

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2011001270A Division JP2011093924A (ja) 1998-12-01 2011-01-06 (−)−ベンラファキシン誘導体並びにその製造方法および使用方法
JP2013172984A Division JP2013256526A (ja) 1998-12-01 2013-08-23 (−)−ベンラファキシン誘導体並びにその製造方法および使用方法

Publications (2)

Publication Number Publication Date
JP2003524613A JP2003524613A (ja) 2003-08-19
JP2003524613A5 true JP2003524613A5 (https=) 2007-01-25

Family

ID=26808068

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000585198A Pending JP2003524613A (ja) 1998-12-01 1999-12-01 (−)−ベンラファキシン誘導体並びにその製造方法および使用方法
JP2011001270A Pending JP2011093924A (ja) 1998-12-01 2011-01-06 (−)−ベンラファキシン誘導体並びにその製造方法および使用方法
JP2013172984A Pending JP2013256526A (ja) 1998-12-01 2013-08-23 (−)−ベンラファキシン誘導体並びにその製造方法および使用方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2011001270A Pending JP2011093924A (ja) 1998-12-01 2011-01-06 (−)−ベンラファキシン誘導体並びにその製造方法および使用方法
JP2013172984A Pending JP2013256526A (ja) 1998-12-01 2013-08-23 (−)−ベンラファキシン誘導体並びにその製造方法および使用方法

Country Status (6)

Country Link
US (9) US6342533B1 (https=)
EP (2) EP1953136A1 (https=)
JP (3) JP2003524613A (https=)
AU (1) AU774408B2 (https=)
CA (1) CA2352324C (https=)
WO (1) WO2000032556A1 (https=)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6241762B1 (en) * 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6342533B1 (en) 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
WO2000076956A2 (en) * 1999-06-15 2000-12-21 American Home Products Corporation Enantiomers of n-desmethyl venlafaxine
US20020035158A1 (en) * 1999-06-15 2002-03-21 American Home Products Corporation Enantiomers of N-desmethyl venlafaxine
WO2000076955A1 (en) * 1999-06-15 2000-12-21 American Home Products Corporation Enantiomers of o-desmethyl venlafaxine
US20020022662A1 (en) * 1999-06-15 2002-02-21 American Home Products Corporation Enantiomers of O-desmethyl venlafaxine
US6348494B1 (en) * 2000-11-21 2002-02-19 American Home Products Corporation Ethers of o-desmethyl venlafaxine
US7291646B2 (en) 1999-11-24 2007-11-06 Wyeth Ethers of O-desmethyl venlafaxine
AU4529101A (en) * 2000-03-07 2001-09-17 Eli Lilly And Company Treatment of psoriasis
DE10042412B4 (de) * 2000-08-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Abgabe von Venlafaxin, und seine Verwendung
ES2243556T3 (es) 2000-10-16 2005-12-01 Conor Medsystems, Inc. Dispositivo medico expandible para proporcionar un agente beneficioso.
JP2004534724A (ja) * 2000-11-01 2004-11-18 センション,インコーポレイテッド 記憶固化を調節するための方法および組成物
US7619005B2 (en) 2000-11-01 2009-11-17 Cognition Pharmaceuticals Llc Methods for treating cognitive impairment in humans with Multiple Sclerosis
US20030232890A1 (en) 2000-11-01 2003-12-18 Sention, Inc. Methods for treating an impairment in memory consolidation
EP1864967A1 (en) * 2001-02-12 2007-12-12 Wyeth Method for preparing O-desmethyl-venlafaxine
US7842083B2 (en) * 2001-08-20 2010-11-30 Innovational Holdings, Llc. Expandable medical device with improved spatial distribution
UA80543C2 (en) * 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine
US7005138B2 (en) * 2001-12-21 2006-02-28 Duramed Pharmaceuticals, Inc. Method of systematically delivering SSRIs
WO2003055475A1 (en) * 2002-01-03 2003-07-10 Lek Pharmaceutical And Chemical Company D.D. Controlled release pharmaceutical formulation containing venlafaxine
US6696496B2 (en) 2002-03-28 2004-02-24 Synthon Bv Low water-soluble venlafaxine salts
EP1485344A1 (en) 2002-03-28 2004-12-15 Synthon B.V. Venlafaxine besylate
NZ537142A (en) * 2002-06-10 2008-01-31 Wyeth Corp Novel formate salt of O-desmethyl-venlafaxine
AU2003281158A1 (en) * 2002-07-12 2004-02-02 Arakis Ltd. The treatment of emesis
CN1232501C (zh) * 2002-11-29 2005-12-21 重庆凯林制药有限公司 用于制备万拉法新中间体的环己醇衍生物的制备工艺
AU2003302147A1 (en) * 2002-12-23 2004-07-14 Osmotica Costa Rica Sociedad Anonima Delivery device containing venlafaxine and memantine and use method thereof
US20070077301A1 (en) * 2002-12-23 2007-04-05 Meyer Glenn A Venlafaxine osmotic device formulation
US7470435B2 (en) * 2003-11-17 2008-12-30 Andrx Pharmaceuticals, Llc Extended release venlafaxine formulation
US20050176680A1 (en) * 2003-12-11 2005-08-11 Sepracor, Inc. Combination of sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
CA2554559A1 (en) * 2004-02-06 2005-08-25 Wyeth Multiparticulate o-desmethylvenlafaxine salts and uses thereof
US7417009B2 (en) * 2004-03-26 2008-08-26 Nalco Company Paraffin inhibitors
US7776358B2 (en) 2004-07-22 2010-08-17 Synthon Ip Inc. Extended release venlafaxine besylate tablets
US20060193912A1 (en) * 2005-02-28 2006-08-31 Penwest Pharmaceuticals Co. Controlled release O-desmethylvenlafaxine formulations
CN101257907A (zh) * 2005-07-06 2008-09-03 塞普拉科公司 左旋佐匹克隆和抗抑郁剂的组合
CA2614209A1 (en) * 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and o-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
GT200600397A (es) * 2005-09-07 2007-08-28 Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales
CA2625832A1 (en) * 2005-10-19 2007-04-26 Vinod Kumar Kansal Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
EP1965780B1 (en) * 2005-12-19 2017-03-08 The University Of Liverpool Propofol derivatives as analgesics
EP1973866A1 (en) 2005-12-20 2008-10-01 Synthon B.V. Process for making desvenlafaxine
JPWO2007086493A1 (ja) * 2006-01-27 2009-06-25 旭化成ファーマ株式会社 経鼻投与用薬剤
TW200806282A (en) * 2006-05-05 2008-02-01 Wyeth Corp Solid dosage formulations
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
EP2121574A1 (en) * 2007-01-09 2009-11-25 Pharmathen S.A. Improved process for the preparation of phenethylamine derivatives
KR101528326B1 (ko) * 2007-02-21 2015-06-11 선오비온 파마슈티컬스 인코포레이티드 (―)o―데스메틸벤라팍신을 포함하는 고체 형태들 및 그들의 용도
US20100330172A1 (en) * 2007-10-16 2010-12-30 Alphapharm Pty Ltd Controlled-release pharmaceutical formulation
AU2008315740A1 (en) 2007-10-26 2009-04-30 Generics [Uk] Limited Process for preparing O-desmethylvenlafaxine
EP2074993A1 (en) 2007-12-19 2009-07-01 Biovail Laboratories International S.r.l. Venlafaxine-containing film-coated modified-release tablets
WO2009084037A2 (en) * 2007-12-20 2009-07-09 Calyx Chemicals And Pharmaceuticals Ltd. Novel process for preparation of o-desmethylvenlafaxine
WO2009144517A1 (en) * 2008-04-14 2009-12-03 Egis Gyógyszergyár Nyilvánosan Müködö Process for the preparation of cyclohexanol derivatives
WO2010090991A1 (en) * 2009-02-04 2010-08-12 Supernus Pharmaceuticals, Inc. Formulations of desvenlafaxine
CZ303249B6 (cs) 2010-04-06 2012-06-20 Zentiva, K.S. Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
US8933123B2 (en) 2010-10-08 2015-01-13 Cadila Healthcare Limited Polymorphic forms of O-desmethyl-venlafaxine succinate
CN104529797A (zh) * 2014-12-05 2015-04-22 南昌市博泽康医药科技有限公司 盐酸文拉法辛手性晶型的制备
CN106692118A (zh) * 2016-11-18 2017-05-24 广州军区广州总医院 文拉法辛在制备预防或治疗轻型脑损伤后认知功能障碍的药物中的应用

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
IE56324B1 (en) 1982-12-13 1991-06-19 American Home Prod Phenethylamine derivatives and intermediates therefor
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US4761501A (en) 1983-10-26 1988-08-02 American Home Products Corporation Substituted phenylacetamides
ATE64735T1 (de) * 1984-05-10 1991-07-15 Ciba Geigy Ag Benzo-(pyrano und thiopyrano)-pyridine.
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
GB8902209D0 (en) 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5733566A (en) 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
US5281624A (en) 1991-09-27 1994-01-25 Eli Lilly And Company N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
AU4542893A (en) 1992-06-23 1994-01-24 Sepracor, Inc. Methods and compositions for treating depression and other disorders using optically pure (-) sibutramine
AU4542993A (en) 1992-06-23 1994-01-24 Sepracor, Inc. Methods and compositions for treating depression and other disorders using optically pure (+) sibutramine
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
DE4319939C2 (de) * 1993-06-16 1996-08-14 Heitz Peter Feuchtwischtuch
PT639374E (pt) * 1993-06-28 2002-07-31 American Home Prod Novos tratamentos utilizado derivados fenetilo
TW344661B (en) 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
CA2176722A1 (en) * 1993-12-28 1995-07-06 Ruth E. Ten Brink Heterocyclic compounds for the treatment of cns and cardiovascular disorders
ATE229328T1 (de) * 1994-02-14 2002-12-15 Wyeth Corp Venlafaxin und seine analoga zum herbeiführen einer verbesserung der kognitiven funktionen
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US5506270A (en) * 1995-01-30 1996-04-09 American Home Products Corporation Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women
US5554383A (en) 1995-04-06 1996-09-10 Trustees Of Tufts College Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
JPH08333340A (ja) * 1995-06-06 1996-12-17 Fujirebio Inc アミノエチルピペリジン誘導体の製造方法
US6274171B1 (en) * 1996-03-25 2001-08-14 American Home Products Corporation Extended release formulation of venlafaxine hydrochloride
WO1997040027A1 (en) * 1996-04-19 1997-10-30 Akzo Nobel N.V. Substituted benzylamines and their use for the treatment of depression
AU3075197A (en) 1996-05-21 1997-12-09 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Novel methods of o-demethylation and n-deprotection
AU4894697A (en) 1997-10-01 1999-04-23 Flemington Pharmaceutical Corporation Buccal, polar and non-polar spray or capsule
US6197828B1 (en) 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
DE60039132D1 (de) 1999-04-06 2008-07-17 Sepracor Inc O-Desmethylvenlafaxin-Succinat
CA2371836C (en) 1999-05-27 2006-01-31 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
WO2000076955A1 (en) 1999-06-15 2000-12-21 American Home Products Corporation Enantiomers of o-desmethyl venlafaxine
US20020022662A1 (en) * 1999-06-15 2002-02-21 American Home Products Corporation Enantiomers of O-desmethyl venlafaxine
CA2375498A1 (en) 1999-06-18 2000-12-28 Biotherapies, Inc. Epithelial cell growth inhibitors
EP1864967A1 (en) * 2001-02-12 2007-12-12 Wyeth Method for preparing O-desmethyl-venlafaxine
UA80543C2 (en) * 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine
NZ537142A (en) * 2002-06-10 2008-01-31 Wyeth Corp Novel formate salt of O-desmethyl-venlafaxine
TWI306092B (en) * 2003-03-11 2009-02-11 Wyeth Corp Process for preparation of phenethylamine derivatives
CA2554559A1 (en) * 2004-02-06 2005-08-25 Wyeth Multiparticulate o-desmethylvenlafaxine salts and uses thereof

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