JP2003524613A5 - - Google Patents
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- Publication number
- JP2003524613A5 JP2003524613A5 JP2000585198A JP2000585198A JP2003524613A5 JP 2003524613 A5 JP2003524613 A5 JP 2003524613A5 JP 2000585198 A JP2000585198 A JP 2000585198A JP 2000585198 A JP2000585198 A JP 2000585198A JP 2003524613 A5 JP2003524613 A5 JP 2003524613A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- venlafaxine
- acceptable salt
- substantially free
- stereoisomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11048898P | 1998-12-01 | 1998-12-01 | |
| US60/110,488 | 1998-12-01 | ||
| US09/450,690 | 1999-11-30 | ||
| US09/450,690 US6342533B1 (en) | 1998-12-01 | 1999-11-30 | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
| PCT/US1999/028303 WO2000032556A1 (en) | 1998-12-01 | 1999-12-01 | Derivatives of (-)-venlafaxine and methods of preparing and using the same |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011001270A Division JP2011093924A (ja) | 1998-12-01 | 2011-01-06 | (−)−ベンラファキシン誘導体並びにその製造方法および使用方法 |
| JP2013172984A Division JP2013256526A (ja) | 1998-12-01 | 2013-08-23 | (−)−ベンラファキシン誘導体並びにその製造方法および使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003524613A JP2003524613A (ja) | 2003-08-19 |
| JP2003524613A5 true JP2003524613A5 (https=) | 2007-01-25 |
Family
ID=26808068
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000585198A Pending JP2003524613A (ja) | 1998-12-01 | 1999-12-01 | (−)−ベンラファキシン誘導体並びにその製造方法および使用方法 |
| JP2011001270A Pending JP2011093924A (ja) | 1998-12-01 | 2011-01-06 | (−)−ベンラファキシン誘導体並びにその製造方法および使用方法 |
| JP2013172984A Pending JP2013256526A (ja) | 1998-12-01 | 2013-08-23 | (−)−ベンラファキシン誘導体並びにその製造方法および使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011001270A Pending JP2011093924A (ja) | 1998-12-01 | 2011-01-06 | (−)−ベンラファキシン誘導体並びにその製造方法および使用方法 |
| JP2013172984A Pending JP2013256526A (ja) | 1998-12-01 | 2013-08-23 | (−)−ベンラファキシン誘導体並びにその製造方法および使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (9) | US6342533B1 (https=) |
| EP (2) | EP1953136A1 (https=) |
| JP (3) | JP2003524613A (https=) |
| AU (1) | AU774408B2 (https=) |
| CA (1) | CA2352324C (https=) |
| WO (1) | WO2000032556A1 (https=) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6241762B1 (en) * | 1998-03-30 | 2001-06-05 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
| US7208010B2 (en) | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
| US6342533B1 (en) | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
| WO2000076956A2 (en) * | 1999-06-15 | 2000-12-21 | American Home Products Corporation | Enantiomers of n-desmethyl venlafaxine |
| US20020035158A1 (en) * | 1999-06-15 | 2002-03-21 | American Home Products Corporation | Enantiomers of N-desmethyl venlafaxine |
| WO2000076955A1 (en) * | 1999-06-15 | 2000-12-21 | American Home Products Corporation | Enantiomers of o-desmethyl venlafaxine |
| US20020022662A1 (en) * | 1999-06-15 | 2002-02-21 | American Home Products Corporation | Enantiomers of O-desmethyl venlafaxine |
| US6348494B1 (en) * | 2000-11-21 | 2002-02-19 | American Home Products Corporation | Ethers of o-desmethyl venlafaxine |
| US7291646B2 (en) | 1999-11-24 | 2007-11-06 | Wyeth | Ethers of O-desmethyl venlafaxine |
| AU4529101A (en) * | 2000-03-07 | 2001-09-17 | Eli Lilly And Company | Treatment of psoriasis |
| DE10042412B4 (de) * | 2000-08-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Abgabe von Venlafaxin, und seine Verwendung |
| ES2243556T3 (es) | 2000-10-16 | 2005-12-01 | Conor Medsystems, Inc. | Dispositivo medico expandible para proporcionar un agente beneficioso. |
| JP2004534724A (ja) * | 2000-11-01 | 2004-11-18 | センション,インコーポレイテッド | 記憶固化を調節するための方法および組成物 |
| US7619005B2 (en) | 2000-11-01 | 2009-11-17 | Cognition Pharmaceuticals Llc | Methods for treating cognitive impairment in humans with Multiple Sclerosis |
| US20030232890A1 (en) | 2000-11-01 | 2003-12-18 | Sention, Inc. | Methods for treating an impairment in memory consolidation |
| EP1864967A1 (en) * | 2001-02-12 | 2007-12-12 | Wyeth | Method for preparing O-desmethyl-venlafaxine |
| US7842083B2 (en) * | 2001-08-20 | 2010-11-30 | Innovational Holdings, Llc. | Expandable medical device with improved spatial distribution |
| UA80543C2 (en) * | 2001-12-04 | 2007-10-10 | Wyeth Corp | Method for the preparation of o-desmethylvenlafaxine |
| US7005138B2 (en) * | 2001-12-21 | 2006-02-28 | Duramed Pharmaceuticals, Inc. | Method of systematically delivering SSRIs |
| WO2003055475A1 (en) * | 2002-01-03 | 2003-07-10 | Lek Pharmaceutical And Chemical Company D.D. | Controlled release pharmaceutical formulation containing venlafaxine |
| US6696496B2 (en) | 2002-03-28 | 2004-02-24 | Synthon Bv | Low water-soluble venlafaxine salts |
| EP1485344A1 (en) | 2002-03-28 | 2004-12-15 | Synthon B.V. | Venlafaxine besylate |
| NZ537142A (en) * | 2002-06-10 | 2008-01-31 | Wyeth Corp | Novel formate salt of O-desmethyl-venlafaxine |
| AU2003281158A1 (en) * | 2002-07-12 | 2004-02-02 | Arakis Ltd. | The treatment of emesis |
| CN1232501C (zh) * | 2002-11-29 | 2005-12-21 | 重庆凯林制药有限公司 | 用于制备万拉法新中间体的环己醇衍生物的制备工艺 |
| AU2003302147A1 (en) * | 2002-12-23 | 2004-07-14 | Osmotica Costa Rica Sociedad Anonima | Delivery device containing venlafaxine and memantine and use method thereof |
| US20070077301A1 (en) * | 2002-12-23 | 2007-04-05 | Meyer Glenn A | Venlafaxine osmotic device formulation |
| US7470435B2 (en) * | 2003-11-17 | 2008-12-30 | Andrx Pharmaceuticals, Llc | Extended release venlafaxine formulation |
| US20050176680A1 (en) * | 2003-12-11 | 2005-08-11 | Sepracor, Inc. | Combination of sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| CA2554559A1 (en) * | 2004-02-06 | 2005-08-25 | Wyeth | Multiparticulate o-desmethylvenlafaxine salts and uses thereof |
| US7417009B2 (en) * | 2004-03-26 | 2008-08-26 | Nalco Company | Paraffin inhibitors |
| US7776358B2 (en) | 2004-07-22 | 2010-08-17 | Synthon Ip Inc. | Extended release venlafaxine besylate tablets |
| US20060193912A1 (en) * | 2005-02-28 | 2006-08-31 | Penwest Pharmaceuticals Co. | Controlled release O-desmethylvenlafaxine formulations |
| CN101257907A (zh) * | 2005-07-06 | 2008-09-03 | 塞普拉科公司 | 左旋佐匹克隆和抗抑郁剂的组合 |
| CA2614209A1 (en) * | 2005-07-06 | 2007-01-11 | Sepracor Inc. | Combinations of eszopiclone and o-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
| GT200600397A (es) * | 2005-09-07 | 2007-08-28 | Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales | |
| CA2625832A1 (en) * | 2005-10-19 | 2007-04-26 | Vinod Kumar Kansal | Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride |
| EP1965780B1 (en) * | 2005-12-19 | 2017-03-08 | The University Of Liverpool | Propofol derivatives as analgesics |
| EP1973866A1 (en) | 2005-12-20 | 2008-10-01 | Synthon B.V. | Process for making desvenlafaxine |
| JPWO2007086493A1 (ja) * | 2006-01-27 | 2009-06-25 | 旭化成ファーマ株式会社 | 経鼻投与用薬剤 |
| TW200806282A (en) * | 2006-05-05 | 2008-02-01 | Wyeth Corp | Solid dosage formulations |
| US20080081067A1 (en) * | 2006-10-03 | 2008-04-03 | Gupta Manishkumar | Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof |
| EP2121574A1 (en) * | 2007-01-09 | 2009-11-25 | Pharmathen S.A. | Improved process for the preparation of phenethylamine derivatives |
| KR101528326B1 (ko) * | 2007-02-21 | 2015-06-11 | 선오비온 파마슈티컬스 인코포레이티드 | (―)o―데스메틸벤라팍신을 포함하는 고체 형태들 및 그들의 용도 |
| US20100330172A1 (en) * | 2007-10-16 | 2010-12-30 | Alphapharm Pty Ltd | Controlled-release pharmaceutical formulation |
| AU2008315740A1 (en) | 2007-10-26 | 2009-04-30 | Generics [Uk] Limited | Process for preparing O-desmethylvenlafaxine |
| EP2074993A1 (en) | 2007-12-19 | 2009-07-01 | Biovail Laboratories International S.r.l. | Venlafaxine-containing film-coated modified-release tablets |
| WO2009084037A2 (en) * | 2007-12-20 | 2009-07-09 | Calyx Chemicals And Pharmaceuticals Ltd. | Novel process for preparation of o-desmethylvenlafaxine |
| WO2009144517A1 (en) * | 2008-04-14 | 2009-12-03 | Egis Gyógyszergyár Nyilvánosan Müködö | Process for the preparation of cyclohexanol derivatives |
| WO2010090991A1 (en) * | 2009-02-04 | 2010-08-12 | Supernus Pharmaceuticals, Inc. | Formulations of desvenlafaxine |
| CZ303249B6 (cs) | 2010-04-06 | 2012-06-20 | Zentiva, K.S. | Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu |
| US8933123B2 (en) | 2010-10-08 | 2015-01-13 | Cadila Healthcare Limited | Polymorphic forms of O-desmethyl-venlafaxine succinate |
| CN104529797A (zh) * | 2014-12-05 | 2015-04-22 | 南昌市博泽康医药科技有限公司 | 盐酸文拉法辛手性晶型的制备 |
| CN106692118A (zh) * | 2016-11-18 | 2017-05-24 | 广州军区广州总医院 | 文拉法辛在制备预防或治疗轻型脑损伤后认知功能障碍的药物中的应用 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| IE56324B1 (en) | 1982-12-13 | 1991-06-19 | American Home Prod | Phenethylamine derivatives and intermediates therefor |
| US4535186A (en) * | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| US4761501A (en) | 1983-10-26 | 1988-08-02 | American Home Products Corporation | Substituted phenylacetamides |
| ATE64735T1 (de) * | 1984-05-10 | 1991-07-15 | Ciba Geigy Ag | Benzo-(pyrano und thiopyrano)-pyridine. |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| GB8902209D0 (en) | 1989-02-01 | 1989-03-22 | Wyeth John And Brother Limited | Preparation of cyclohexanol derivatives and novel thioamide intermediates |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5281624A (en) | 1991-09-27 | 1994-01-25 | Eli Lilly And Company | N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| AU4542893A (en) | 1992-06-23 | 1994-01-24 | Sepracor, Inc. | Methods and compositions for treating depression and other disorders using optically pure (-) sibutramine |
| AU4542993A (en) | 1992-06-23 | 1994-01-24 | Sepracor, Inc. | Methods and compositions for treating depression and other disorders using optically pure (+) sibutramine |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| DE4319939C2 (de) * | 1993-06-16 | 1996-08-14 | Heitz Peter | Feuchtwischtuch |
| PT639374E (pt) * | 1993-06-28 | 2002-07-31 | American Home Prod | Novos tratamentos utilizado derivados fenetilo |
| TW344661B (en) | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
| CA2176722A1 (en) * | 1993-12-28 | 1995-07-06 | Ruth E. Ten Brink | Heterocyclic compounds for the treatment of cns and cardiovascular disorders |
| ATE229328T1 (de) * | 1994-02-14 | 2002-12-15 | Wyeth Corp | Venlafaxin und seine analoga zum herbeiführen einer verbesserung der kognitiven funktionen |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US5506270A (en) * | 1995-01-30 | 1996-04-09 | American Home Products Corporation | Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women |
| US5554383A (en) | 1995-04-06 | 1996-09-10 | Trustees Of Tufts College | Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression |
| US5541199A (en) * | 1995-06-02 | 1996-07-30 | American Home Products Corporation | Chroman-2-ylmethylamino derivatives |
| JPH08333340A (ja) * | 1995-06-06 | 1996-12-17 | Fujirebio Inc | アミノエチルピペリジン誘導体の製造方法 |
| US6274171B1 (en) * | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
| WO1997040027A1 (en) * | 1996-04-19 | 1997-10-30 | Akzo Nobel N.V. | Substituted benzylamines and their use for the treatment of depression |
| AU3075197A (en) | 1996-05-21 | 1997-12-09 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Novel methods of o-demethylation and n-deprotection |
| AU4894697A (en) | 1997-10-01 | 1999-04-23 | Flemington Pharmaceutical Corporation | Buccal, polar and non-polar spray or capsule |
| US6197828B1 (en) | 1998-12-01 | 2001-03-06 | Sepracor, Inc. | Derivatives of (+)-venlafaxine and methods of preparing and using the same |
| US6342533B1 (en) * | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
| DE60039132D1 (de) | 1999-04-06 | 2008-07-17 | Sepracor Inc | O-Desmethylvenlafaxin-Succinat |
| CA2371836C (en) | 1999-05-27 | 2006-01-31 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| WO2000076955A1 (en) | 1999-06-15 | 2000-12-21 | American Home Products Corporation | Enantiomers of o-desmethyl venlafaxine |
| US20020022662A1 (en) * | 1999-06-15 | 2002-02-21 | American Home Products Corporation | Enantiomers of O-desmethyl venlafaxine |
| CA2375498A1 (en) | 1999-06-18 | 2000-12-28 | Biotherapies, Inc. | Epithelial cell growth inhibitors |
| EP1864967A1 (en) * | 2001-02-12 | 2007-12-12 | Wyeth | Method for preparing O-desmethyl-venlafaxine |
| UA80543C2 (en) * | 2001-12-04 | 2007-10-10 | Wyeth Corp | Method for the preparation of o-desmethylvenlafaxine |
| NZ537142A (en) * | 2002-06-10 | 2008-01-31 | Wyeth Corp | Novel formate salt of O-desmethyl-venlafaxine |
| TWI306092B (en) * | 2003-03-11 | 2009-02-11 | Wyeth Corp | Process for preparation of phenethylamine derivatives |
| CA2554559A1 (en) * | 2004-02-06 | 2005-08-25 | Wyeth | Multiparticulate o-desmethylvenlafaxine salts and uses thereof |
-
1999
- 1999-11-30 US US09/450,690 patent/US6342533B1/en not_active Expired - Lifetime
- 1999-12-01 JP JP2000585198A patent/JP2003524613A/ja active Pending
- 1999-12-01 WO PCT/US1999/028303 patent/WO2000032556A1/en not_active Ceased
- 1999-12-01 EP EP07120208A patent/EP1953136A1/en not_active Ceased
- 1999-12-01 EP EP99968056A patent/EP1135359A1/en not_active Ceased
- 1999-12-01 CA CA2352324A patent/CA2352324C/en not_active Expired - Fee Related
- 1999-12-01 AU AU24749/00A patent/AU774408B2/en not_active Ceased
-
2001
- 2001-12-14 US US10/014,592 patent/US6441048B1/en not_active Expired - Lifetime
-
2002
- 2002-08-19 US US10/222,815 patent/US6911479B2/en not_active Expired - Lifetime
-
2004
- 2004-03-23 US US10/806,423 patent/US20040180952A1/en not_active Abandoned
-
2006
- 2006-05-05 US US11/418,138 patent/US20060199861A1/en not_active Abandoned
- 2006-05-05 US US11/418,137 patent/US20060199860A1/en not_active Abandoned
-
2011
- 2011-01-06 JP JP2011001270A patent/JP2011093924A/ja active Pending
-
2012
- 2012-05-25 US US13/481,584 patent/US8642662B2/en not_active Expired - Fee Related
-
2013
- 2013-08-23 JP JP2013172984A patent/JP2013256526A/ja active Pending
- 2013-12-23 US US14/139,339 patent/US9072700B2/en not_active Expired - Fee Related
-
2015
- 2015-07-01 US US14/789,327 patent/US20150299102A1/en not_active Abandoned
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