JP2003501081A5 - - Google Patents
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- Publication number
- JP2003501081A5 JP2003501081A5 JP2001502556A JP2001502556A JP2003501081A5 JP 2003501081 A5 JP2003501081 A5 JP 2003501081A5 JP 2001502556 A JP2001502556 A JP 2001502556A JP 2001502556 A JP2001502556 A JP 2001502556A JP 2003501081 A5 JP2003501081 A5 JP 2003501081A5
- Authority
- JP
- Japan
- Prior art keywords
- stem cells
- cell
- cells
- human
- cell growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000130 stem cell Anatomy 0.000 description 25
- 238000000034 method Methods 0.000 description 22
- 239000003112 inhibitor Substances 0.000 description 19
- 230000010261 cell growth Effects 0.000 description 16
- 210000004027 cell Anatomy 0.000 description 13
- 239000002609 medium Substances 0.000 description 9
- 210000001988 somatic stem cell Anatomy 0.000 description 9
- 210000001671 embryonic stem cell Anatomy 0.000 description 8
- 230000032823 cell division Effects 0.000 description 7
- 108090000695 Cytokines Proteins 0.000 description 6
- 102000004127 Cytokines Human genes 0.000 description 6
- 230000004663 cell proliferation Effects 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 230000002401 inhibitory effect Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 210000005260 human cell Anatomy 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 108090000266 Cyclin-dependent kinases Proteins 0.000 description 2
- 102000003903 Cyclin-dependent kinases Human genes 0.000 description 2
- 102000014150 Interferons Human genes 0.000 description 2
- 108010050904 Interferons Proteins 0.000 description 2
- 102000004887 Transforming Growth Factor beta Human genes 0.000 description 2
- 108090001012 Transforming Growth Factor beta Proteins 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000006907 apoptotic process Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000024245 cell differentiation Effects 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 2
- 210000002216 heart Anatomy 0.000 description 2
- 229940079322 interferon Drugs 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000001537 neural effect Effects 0.000 description 2
- 238000006386 neutralization reaction Methods 0.000 description 2
- 210000000496 pancreas Anatomy 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 230000000392 somatic effect Effects 0.000 description 2
- 241000894007 species Species 0.000 description 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 2
- 102000015696 Interleukins Human genes 0.000 description 1
- 108010063738 Interleukins Proteins 0.000 description 1
- 230000011712 cell development Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000004992 fission Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003966 growth inhibitor Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000003394 haemopoietic effect Effects 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 229940047122 interleukins Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR99/07011 | 1999-06-03 | ||
| FR9907011A FR2794473B1 (fr) | 1999-06-03 | 1999-06-03 | Procede de multiplication de cellules souches |
| PCT/FR2000/001486 WO2000075290A1 (fr) | 1999-06-03 | 2000-05-30 | Procede de multiplication de cellules souches |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003501081A JP2003501081A (ja) | 2003-01-14 |
| JP2003501081A5 true JP2003501081A5 (https=) | 2007-06-14 |
Family
ID=9546326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001502556A Pending JP2003501081A (ja) | 1999-06-03 | 2000-05-30 | 幹細胞の増殖工程 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7601534B1 (https=) |
| EP (1) | EP1181354A1 (https=) |
| JP (1) | JP2003501081A (https=) |
| CA (1) | CA2375485A1 (https=) |
| FR (1) | FR2794473B1 (https=) |
| WO (1) | WO2000075290A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005077404A1 (en) | 2004-02-13 | 2005-08-25 | Stem Cell Therapeutics Corp. | Use of luteinizing hormone (lh) and chorionic gonadotropin (hcg) for proliferation of neural stem cells and neurogenesis |
| CA2582567A1 (en) * | 2004-10-07 | 2006-04-13 | Stem Cell Therapeutics Corp. | Stimulation of proliferation of pluripotential stem cells through administration of pregnancy associated compounds |
| KR20080103108A (ko) * | 2006-03-17 | 2008-11-26 | 스템 셀 테라퓨틱스 코포레이션 | 신경 장애 치료를 위한 ｌｈ 또는 ｈｃｇ 및 ｅｐｏ의 투여방법 |
| GB201111244D0 (en) * | 2011-06-30 | 2011-08-17 | Konink Nl Akademie Van Wetenschappen Knaw | Culture media for stem cells |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| ES2579909T3 (es) | 2009-02-03 | 2016-08-17 | Koninklijke Nederlandse Akademie Van Wetenschappen | Medio de cultivo para células madre epiteliales y organoides que comprenden dichas células madre |
| WO2011069091A1 (en) | 2009-12-04 | 2011-06-09 | Boston Biomedical Research Institute, Inc. | Method for cloning pluripotent stem cells |
| US9164079B2 (en) * | 2011-03-17 | 2015-10-20 | Greyledge Technologies Llc | Systems for autologous biological therapeutics |
| US9249394B2 (en) | 2011-03-25 | 2016-02-02 | Kyoto University | Method for producing epithelial stem cells |
| GB201721615D0 (en) | 2017-12-21 | 2018-02-07 | Koninklijke Nederlandse Akademie Van Wetenschappen | Immune cell organoid co-cultures |
| WO2024259127A2 (en) * | 2023-06-13 | 2024-12-19 | The Children's Medical Center Corporation | Methods for generating human amniotic membrane and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08205860A (ja) * | 1994-01-21 | 1996-08-13 | Usa Government | 造血細胞の膨大化および移植方法 |
| DE4422667A1 (de) * | 1994-06-30 | 1996-01-04 | Boehringer Ingelheim Int | Verfahren zur Herstellung und Züchtung hämatopoetischer Vorläuferzellen |
| EP0891419A4 (en) * | 1996-03-12 | 2000-03-01 | Life Technologies Inc | NUTRIENT ADDITIVE FOR HEMATOPOETIC CELL CULTURES |
| EP0834556A1 (en) * | 1996-09-25 | 1998-04-08 | Academisch Ziekenhuis Leiden | Methods for culturing cells |
| JPH10136978A (ja) * | 1996-11-08 | 1998-05-26 | Otsuka Pharmaceut Co Ltd | 造血幹細胞の培養方法 |
| US6084060A (en) * | 1996-12-09 | 2000-07-04 | Imclone Systems Incorporated | Composition and method for preserving progenitor cells |
| JPH10295369A (ja) * | 1997-02-26 | 1998-11-10 | Japan Tobacco Inc | 造血幹細胞の製造方法 |
-
1999
- 1999-06-03 FR FR9907011A patent/FR2794473B1/fr not_active Expired - Fee Related
-
2000
- 2000-05-30 EP EP00936985A patent/EP1181354A1/fr not_active Withdrawn
- 2000-05-30 JP JP2001502556A patent/JP2003501081A/ja active Pending
- 2000-05-30 WO PCT/FR2000/001486 patent/WO2000075290A1/fr not_active Ceased
- 2000-05-30 CA CA002375485A patent/CA2375485A1/fr not_active Abandoned
- 2000-05-30 US US09/980,484 patent/US7601534B1/en not_active Expired - Fee Related
-
2009
- 2009-09-08 US US12/555,062 patent/US20090325289A1/en not_active Abandoned
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