|
US4487934A
(en)
|
1980-06-06 |
1984-12-11 |
Hoechst-Roussel Pharmaceuticals Inc. |
Method of preparing poly-substituted acylbenzenes
|
|
US4501729A
(en)
*
|
1982-12-13 |
1985-02-26 |
Research Corporation |
Aerosolized amiloride treatment of retained pulmonary secretions
|
|
DE3326472A1
(de)
|
1983-07-22 |
1985-02-14 |
Hoechst Ag, 6230 Frankfurt |
Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
|
|
ATE39691T1
(de)
|
1984-04-06 |
1989-01-15 |
Zambon Spa |
Optisch wirksame ketale, verfahren zu deren herstellung und deren verwendung in der synthese von alpha-arylalkansaeuren.
|
|
KR930701992A
(ko)
*
|
1990-10-05 |
1993-09-08 |
웨인 알.조운즈 |
환자의 폐에 잔존하는 점액 분비물의 제거 방법
|
|
US5173414A
(en)
*
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
US5292498A
(en)
*
|
1991-06-19 |
1994-03-08 |
The University Of North Carolina At Chapel Hill |
Method of treating lung disease with uridine triphosphates
|
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
|
US5686436A
(en)
|
1993-05-13 |
1997-11-11 |
Hiv Diagnostics, Inc. |
Multi-faceted method to repress reproduction of latent viruses in humans and animals
|
|
US5512269A
(en)
*
|
1993-06-09 |
1996-04-30 |
Burroughs Wellcome, Co. |
Method of treating retained pulmonary secretions
|
|
US5498531A
(en)
|
1993-09-10 |
1996-03-12 |
President And Fellows Of Harvard College |
Intron-mediated recombinant techniques and reagents
|
|
US5750398A
(en)
*
|
1993-11-30 |
1998-05-12 |
David C. Johnson |
Vector, element and method for inhibiting immune recognition
|
|
US5604090A
(en)
*
|
1994-06-06 |
1997-02-18 |
Fred Hutchinson Cancer Research Center |
Method for increasing transduction of cells by adeno-associated virus vectors
|
|
US5656256A
(en)
*
|
1994-12-14 |
1997-08-12 |
The University Of North Carolina At Chapel Hill |
Methods of treating lung disease by an aerosol containing benzamil or phenamil
|
|
US5843742A
(en)
*
|
1994-12-16 |
1998-12-01 |
Avigen Incorporated |
Adeno-associated derived vector systems for gene delivery and integration into target cells
|
|
US6281010B1
(en)
*
|
1995-06-05 |
2001-08-28 |
The Trustees Of The University Of Pennsylvania |
Adenovirus gene therapy vehicle and cell line
|
|
US5635160A
(en)
*
|
1995-06-07 |
1997-06-03 |
The University Of North Carolina At Chapel Hill |
Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
|
|
US5628984A
(en)
*
|
1995-07-31 |
1997-05-13 |
University Of North Carolina At Chapel Hill |
Method of detecting lung disease
|
|
CA2230195A1
(en)
*
|
1995-08-21 |
1997-02-27 |
Duke University |
A method to increase the density of antigen on antigen presenting cells
|
|
US5801030A
(en)
*
|
1995-09-01 |
1998-09-01 |
Genvec, Inc. |
Methods and vectors for site-specific recombination
|
|
US5855918A
(en)
*
|
1995-09-12 |
1999-01-05 |
Genentech, Inc. |
Cystic fibrosis therapy
|
|
US6083702A
(en)
*
|
1995-12-15 |
2000-07-04 |
Intronn Holdings Llc |
Methods and compositions for use in spliceosome mediated RNA trans-splicing
|
|
ATE354957T1
(de)
|
1995-12-15 |
2006-03-15 |
Intronn Inc |
Durch trans-spaltung erhaltene therapeutische molekule
|
|
US6420347B1
(en)
*
|
1997-03-27 |
2002-07-16 |
Inspire Pharmaceuticals, Inc. |
Method of treating ciliary dyskinesia with uridine triphosphates and related compounds
|
|
JP2001500497A
(ja)
|
1996-09-06 |
2001-01-16 |
トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスに指図される遺伝子治療の方法
|
|
AU5588298A
(en)
|
1996-12-02 |
1998-06-29 |
Cell Genesys, Inc. |
Adeno-associated viral vector-mediated delivery of dna to cells of the liver
|
|
US6287569B1
(en)
*
|
1997-04-10 |
2001-09-11 |
The Regents Of The University Of California |
Vaccines with enhanced intracellular processing
|
|
FR2763845B1
(fr)
|
1997-05-30 |
2003-04-18 |
Centre Nat Rech Scient |
Produits anti-cancereux pour le traitement de la mucoviscidose
|
|
US6156303A
(en)
*
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6037177A
(en)
|
1997-08-08 |
2000-03-14 |
Cell Genesys, Inc. |
Method for increasing the efficiency of recombinant AAV production
|
|
EP1011688B1
(en)
*
|
1997-08-29 |
2005-02-02 |
The University of North Carolina at Chapel Hill |
Use of uridine 5'-diphosphate and analogs thereof for the treatment of lung diseases
|
|
US6436392B1
(en)
|
1998-05-20 |
2002-08-20 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors
|
|
JP4633927B2
(ja)
*
|
1998-05-22 |
2011-02-16 |
インスパイアー ファーマシューティカルズ，インコーポレイティド |
治療用ジヌクレオチドおよび誘導体
|
|
US6290951B1
(en)
*
|
1998-08-01 |
2001-09-18 |
Alfacell Corporation |
Alteration of the cell cycle in vivo, and particularly for inducing apoptosis of tumor cells
|
|
US6200560B1
(en)
*
|
1998-10-20 |
2001-03-13 |
Avigen, Inc. |
Adeno-associated virus vectors for expression of factor VIII by target cells
|
|
EP1143896B1
(en)
*
|
1998-10-20 |
2006-12-13 |
The University of North Carolina at Chapel Hill |
Methods of hydrating the nasal mucosal surface
|
|
US6221349B1
(en)
*
|
1998-10-20 |
2001-04-24 |
Avigen, Inc. |
Adeno-associated vectors for expression of factor VIII by target cells
|
|
US6855549B1
(en)
*
|
1998-11-23 |
2005-02-15 |
The University Of Iowa Research Foundation |
Methods and compositions for increasing the infectivity of gene transfer vectors
|
|
US6926911B1
(en)
*
|
1998-12-22 |
2005-08-09 |
The University Of North Carolina At Chapel Hill |
Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs
|
|
EP1153612A4
(en)
|
1999-02-10 |
2003-06-18 |
Takashi Tsuruo |
Anticancer agent potentiators
|
|
US6306663B1
(en)
*
|
1999-02-12 |
2001-10-23 |
Proteinex, Inc. |
Controlling protein levels in eucaryotic organisms
|
|
JP4969002B2
(ja)
|
1999-06-08 |
2012-07-04 |
ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン |
ｒＡＡＶ形質導入を増加するための化合物および方法
|
|
US7122335B1
(en)
*
|
1999-06-08 |
2006-10-17 |
University Of Iowa Research Foundation |
Compounds and methods to enhance rAAV transduction
|
|
HK1047091B
(en)
*
|
1999-07-19 |
2008-07-04 |
University Of North Carolina At Chapel Hill |
Pharmacologically active compounds with two covalently linked active principles (sodium channel blocker/p2y2 receptor agonist) for the treatment of mucosal surfaces
|
|
US6475537B1
(en)
*
|
2000-07-27 |
2002-11-05 |
Rhodia Inc. |
Hops acid antibacterial compositions
|
|
US6416759B1
(en)
*
|
1999-09-30 |
2002-07-09 |
The Regents Of The University Of California |
Antiproliferative Sgk reagents and methods
|
|
EP1224313A1
(en)
|
1999-10-07 |
2002-07-24 |
University of Iowa Research Foundation |
Adeno-associated viruses and uses thereof
|
|
JP2003511082A
(ja)
*
|
1999-10-12 |
2003-03-25 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
第ｖｉｉｉ因子をコードするアデノ随伴ウィルスベクターとその使用法
|
|
AU7895700A
(en)
*
|
1999-10-15 |
2001-04-30 |
Dalhousie University |
Method and vector for producing and transferring trans-spliced peptides
|
|
US20020132770A1
(en)
*
|
1999-10-27 |
2002-09-19 |
Caplan Michael T. |
Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
|
|
AU2001240018A1
(en)
*
|
2000-03-03 |
2001-09-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Adeno-associated viral compositions and methods
|
|
CA2302627A1
(en)
|
2000-03-23 |
2001-09-23 |
Rashmi Kothary |
Constructs comprising the enac promoter sequence and a reporter gene for screening pharmaceuticals
|
|
US20020076754A1
(en)
*
|
2000-04-20 |
2002-06-20 |
Liangwu Sun |
Overcoming AAV vector size limitation through viral DNA hetero-dimerization
|
|
US7056502B2
(en)
|
2000-04-28 |
2006-06-06 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav vectors with AAV5 capsids and AAV5 vectors pseudotyped in heterologous capsids
|
|
US20020128203A1
(en)
*
|
2000-09-20 |
2002-09-12 |
Laurent Schild |
Methods of identifying inhibitory compounds and uses thereof
|
|
AU2001289438A1
(en)
|
2000-09-22 |
2002-04-02 |
Galephar M/F |
Pharmaceutical semi-solid composition of isotretinoin
|
|
WO2002028348A2
(en)
*
|
2000-10-04 |
2002-04-11 |
The Children's Hospital Of Philadelphia |
Compositions and methods for treatment of cystic fibrosis
|
|
AU2002251844A1
(en)
*
|
2001-02-02 |
2002-10-03 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of colon cancer
|
|
US20030013137A1
(en)
|
2001-03-13 |
2003-01-16 |
Barak Larry S. |
Automated methods of detecting receptor activity
|
|
CA2482124C
(en)
*
|
2001-04-19 |
2008-10-07 |
Uab Research Foundation |
Methods of treatment using an epithelial sodium channel blocker and an inhibitor of the mineralocorticoid receptor
|
|
AU2002308481A1
(en)
|
2001-05-01 |
2002-11-11 |
Senomyx, Inc. |
High throughput cell-based assay for monitoring sodium channel activity and discovery of salty taste modulating compounds
|
|
US20030003583A1
(en)
*
|
2001-06-08 |
2003-01-02 |
Raphael Hirsch |
Regulation of transgene expression following AAV transduction
|
|
CA2453405A1
(en)
*
|
2001-07-13 |
2003-01-23 |
University Of Iowa Research Foundation |
Pseudotyped adeno-associated viruses and uses thereof
|
|
US8241622B2
(en)
*
|
2001-07-13 |
2012-08-14 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors with intravector heterologous terminal palindromic sequences
|
|
EP1478655A4
(en)
|
2001-12-31 |
2006-05-10 |
Algos Therapeutics Inc |
METHODS AND SUBSTANCES FOR ENAC-BETA MODULATION
|
|
ATE405670T1
(de)
|
2002-05-13 |
2008-09-15 |
Arexis Ab |
Autoimmunerkrankungen und nadph-oxidase-defekte
|
|
AU2004227358B8
(en)
|
2003-03-31 |
2009-12-10 |
Targeted Genetics Corporation |
Compounds and methods to enhance rAAV transduction
|
|
EP1486567A1
(en)
|
2003-06-11 |
2004-12-15 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Improved adeno-associated virus (AAV) vector for gene therapy
|
|
SI1633772T1
(sl)
|
2003-06-19 |
2016-06-30 |
Genzyme Corporation |
AAV virioni z zmanjšano imunoreaktivnostjo in uporaba za ta namen
|
|
US7655467B2
(en)
|
2003-11-14 |
2010-02-02 |
The University Of Washington |
Compositions and methods for systemic nucleic acid sequence delivery
|
|
WO2005116224A2
(en)
|
2004-05-18 |
2005-12-08 |
Children's Memorial Hospital |
Tetracycline-regulated adeno-associated viral (aav) vectors for gene delivery to the nervous system
|
|
EP1602926A1
(en)
|
2004-06-04 |
2005-12-07 |
University of Geneva |
Novel means and methods for the treatment of hearing loss and phantom hearing
|
|
WO2007127464A2
(en)
|
2006-04-28 |
2007-11-08 |
University Of Iowa Research Foundation |
Methods and compounds to modulate parvovirus transduction of mammalian cells or to alter virus infection, method to identify a viral receptor or co-receptor
|
|
EP2184073A4
(en)
*
|
2007-08-24 |
2010-10-20 |
Kyowa Hakko Kirin Co Ltd |
AGAINST PROTEASE HEMMER RESISTANT CANCER THERAPEUTICS
|