JP2004521123A5 - - Google Patents
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- Publication number
- JP2004521123A5 JP2004521123A5 JP2002562375A JP2002562375A JP2004521123A5 JP 2004521123 A5 JP2004521123 A5 JP 2004521123A5 JP 2002562375 A JP2002562375 A JP 2002562375A JP 2002562375 A JP2002562375 A JP 2002562375A JP 2004521123 A5 JP2004521123 A5 JP 2004521123A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- amino acid
- group
- acid residues
- glycine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26595501P | 2001-02-02 | 2001-02-02 | |
| PCT/US2002/003201 WO2002062369A2 (en) | 2001-02-02 | 2002-02-04 | Uroguanylin and cyclooxygenase-2 inhibitor combinations for inhibition of intestinal cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004521123A JP2004521123A (ja) | 2004-07-15 |
| JP2004521123A5 true JP2004521123A5 (https=) | 2005-12-22 |
Family
ID=23012573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002562375A Withdrawn JP2004521123A (ja) | 2001-02-02 | 2002-02-04 | 腸癌阻害のためのウログアニリンおよびシクロオキシゲナーゼ−２阻害薬の組合わせ |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1365753A2 (https=) |
| JP (1) | JP2004521123A (https=) |
| AU (1) | AU2002235520A1 (https=) |
| CA (1) | CA2435835A1 (https=) |
| WO (1) | WO2002062369A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2905585C (en) * | 2001-03-29 | 2020-02-18 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for the treatment and/or prevention of cancer or polyps |
| EP1911763B1 (en) | 2003-01-28 | 2010-08-11 | Ironwood Pharmaceuticals, Inc. | Compositions for the treatment of gastrointestinal disorders |
| US7371727B2 (en) | 2003-01-28 | 2008-05-13 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US7304036B2 (en) | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| JP2007501866A (ja) | 2003-06-13 | 2007-02-01 | マイクロバイア インコーポレイテッド | 胃腸疾患の治療のための方法および組成物 |
| US7494979B2 (en) | 2003-06-13 | 2009-02-24 | Ironwood Pharmaceuticals, Inc. | Method for treating congestive heart failure and other disorders |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| WO2009149278A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2522968T3 (es) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| AU2009270833B2 (en) | 2008-07-16 | 2015-02-19 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| PE20110543A1 (es) | 2008-08-15 | 2011-08-04 | Ironwood Pharmaceuticals Inc | Formulacion solida oral que comprende linaclotida, cation de calcio y leucina |
| WO2010027405A2 (en) * | 2008-09-04 | 2010-03-11 | Ironwood Pharmaceuticals, Inc. | Stable solid formulations of gc-c receptor agonist polypeptides suitable for oral administration |
| US20100221329A1 (en) | 2008-12-03 | 2010-09-02 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase c agonists and methods of use |
| CA2770077A1 (en) | 2009-08-06 | 2011-02-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprising linaclotide |
| UA108636C2 (xx) | 2010-02-17 | 2015-05-25 | Пептид | |
| EP2603232B1 (en) | 2010-08-11 | 2019-09-25 | Ironwood Pharmaceuticals, Inc. | Stable formulations of linaclotide |
| WO2012037380A2 (en) | 2010-09-15 | 2012-03-22 | Synergy Pharmaceuticals Inc. | Formulations of guanylate cyclase c agonists and methods of use |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| MX347354B (es) | 2011-08-17 | 2017-04-24 | Ironwood Pharmaceuticals Inc | Tratamientos para trastornos gastrointestinales. |
| AU2014235215A1 (en) | 2013-03-15 | 2015-10-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6034256A (en) * | 1997-04-21 | 2000-03-07 | G.D. Searle & Co. | Substituted benzopyran derivatives for the treatment of inflammation |
| US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
-
2002
- 2002-02-04 CA CA002435835A patent/CA2435835A1/en not_active Abandoned
- 2002-02-04 EP EP02702137A patent/EP1365753A2/en not_active Withdrawn
- 2002-02-04 JP JP2002562375A patent/JP2004521123A/ja not_active Withdrawn
- 2002-02-04 AU AU2002235520A patent/AU2002235520A1/en not_active Abandoned
- 2002-02-04 WO PCT/US2002/003201 patent/WO2002062369A2/en not_active Ceased
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