JP2003501038A - 蛋白質キナーゼ - Google Patents

蛋白質キナーゼ

Info

Publication number
JP2003501038A
JP2003501038A JP2001500781A JP2001500781A JP2003501038A JP 2003501038 A JP2003501038 A JP 2003501038A JP 2001500781 A JP2001500781 A JP 2001500781A JP 2001500781 A JP2001500781 A JP 2001500781A JP 2003501038 A JP2003501038 A JP 2003501038A
Authority
JP
Japan
Prior art keywords
sequence number
seq
sequence
polypeptide
kinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2001500781A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003501038A5 (enExample
Inventor
プラウマン,グレゴリー・ディー
マルティネス,リカルド
ホワイト,デイビッド
シュダーサナム,スチャ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sugen LLC
Original Assignee
Sugen LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sugen LLC filed Critical Sugen LLC
Publication of JP2003501038A publication Critical patent/JP2003501038A/ja
Publication of JP2003501038A5 publication Critical patent/JP2003501038A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2001500781A 1999-05-28 2000-05-26 蛋白質キナーゼ Withdrawn JP2003501038A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13650399P 1999-05-28 1999-05-28
US60/136,503 1999-05-28
PCT/US2000/014842 WO2000073469A2 (en) 1999-05-28 2000-05-26 Protein kinases

Publications (2)

Publication Number Publication Date
JP2003501038A true JP2003501038A (ja) 2003-01-14
JP2003501038A5 JP2003501038A5 (enExample) 2007-06-14

Family

ID=22473127

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001500781A Withdrawn JP2003501038A (ja) 1999-05-28 2000-05-26 蛋白質キナーゼ

Country Status (6)

Country Link
US (1) US20060234344A1 (enExample)
EP (1) EP1180151A2 (enExample)
JP (1) JP2003501038A (enExample)
AU (1) AU5173400A (enExample)
CA (1) CA2383244A1 (enExample)
WO (1) WO2000073469A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008522596A (ja) * 2004-12-10 2008-07-03 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 血清/糖質コルチコイド調節キナーゼの使用

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US20020028772A1 (en) * 1997-05-21 2002-03-07 Children's Med. Corporation, Modulators of activity of G-protein-coupled receptor kinases
US7037891B2 (en) 1997-05-21 2006-05-02 Children's Medical Center Corporation Methods of modulating G-protein-coupled receptor kinase-associated signal transduction
AU5254399A (en) 1998-08-04 2000-02-28 Immunex Corporation Human cdnas encoding polypeptides having kinase functions
AU5252799A (en) 1998-08-04 2000-02-28 Immunex Corporation Ikr-1 and ikr-2, protein kinases which are related to the i kappa b kinases
US20030028004A1 (en) * 2000-12-22 2003-02-06 Millennium Pharmaceuticals, Inc. 68730 and 69112, protein kinase molecules and uses therefor
US20020077312A1 (en) * 2000-09-25 2002-06-20 Millennium Pharmaceuticals, Inc. 3700, a novel human protein kinase and uses therefor
US6660490B2 (en) * 1998-12-11 2003-12-09 Millennnium Pharmaceuticals, Inc. CARK protein and nucleic acid molecules and uses therefor
US6261818B1 (en) * 1998-12-11 2001-07-17 Millennium Pharmaceuticals, Inc. CARK protein and nucleic acid molecules and uses therefor
EP1181374A4 (en) 1999-05-28 2003-04-23 Immunex Corp NEW HUMAN AND MURINE KINASES
US7001752B1 (en) 1999-05-28 2006-02-21 Immunex Corporation Murine and human kinases
US6656698B1 (en) * 1999-06-30 2003-12-02 Millennium Pharmaceuticals, Inc. 12832, a novel human kinase-like molecule and uses thereof
EP1484408A1 (en) * 1999-09-28 2004-12-08 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
JP2003510082A (ja) * 1999-09-28 2003-03-18 レキシコン・ジェネティクス・インコーポレーテッド ヒトキナーゼタンパク質およびそれをコードするポリヌクレオチド
US6716616B1 (en) 1999-09-28 2004-04-06 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
JP2003511028A (ja) * 1999-10-07 2003-03-25 ジェネンテック・インコーポレーテッド 新規ポリペプチド、その核酸および新脈管形成および血管新生におけるその使用のための方法
US6428980B1 (en) 1999-11-16 2002-08-06 Rigel Pharmaceuticals, Inc. Nucleic acids encoding RIP3 associated cell cycle proteins
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EP1255819A2 (en) * 2000-02-17 2002-11-13 Incyte Genomics, Inc. Human kinases
US6864078B2 (en) 2000-02-29 2005-03-08 Millennium Pharmaceuticals, Inc. 14790, novel protein kinase molecule and uses therefor
US7198930B2 (en) 2000-02-29 2007-04-03 Millennium Pharmaceuticals, Inc. Human protein kinase, phosphatase, and protease family members and uses thereof
US20020192204A1 (en) * 2000-08-21 2002-12-19 Rosana Kapeller-Libermann 15985, a novel human serine/threonine protein kinase family member and uses thereof
WO2001066762A1 (en) * 2000-03-08 2001-09-13 Merck Patent Gmbh Human extracellular signal regulated kinases
US6458561B1 (en) 2000-03-13 2002-10-01 Incyte Genomics, Inc. Human NIM1 kinase
EP1272640A2 (en) 2000-03-24 2003-01-08 Millennium Pharmaceuticals, Inc. 3714, 16742, 23546, and 13887 novel protein kinase molecules and uses therefor
US20030198953A1 (en) * 2000-03-30 2003-10-23 Spytek Kimberly A. Novel proteins and nucleic acids encoding same
US20020090701A1 (en) * 2000-04-13 2002-07-11 Rosana Kapeller-Libermann 14257 novel protein kinase molecules and their uses therefor
EP1276873A2 (en) 2000-04-25 2003-01-22 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
WO2001081558A2 (en) * 2000-04-25 2001-11-01 Millennium Pharmaceuticals, Inc. 13295 novel protein kinase molecules and uses therefor
JP2003532412A (ja) * 2000-05-12 2003-11-05 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 新規セリン−トレオニン・キナーゼ−4
CA2408468A1 (en) * 2000-05-12 2001-11-15 Merck Patent Gesellschaft Mit Beschraenkter Haftung Serine-threonine kinase-3
WO2001090160A2 (en) * 2000-05-26 2001-11-29 Bayer Aktiengesellschaft REGULATION OF HUMAN p78-LIKE SERINE/THREONINE KINASE
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US6413756B2 (en) * 2000-06-06 2002-07-02 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
US6323016B1 (en) 2000-06-09 2001-11-27 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
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AU2001279106A1 (en) * 2000-07-28 2002-02-13 Chiron Corporation Isolation of drosophila and human polynucleotides encoding par-1 kinase, polypeptides encoded by the polynucleotides and methods utilizing the polynucleotides and polypeptides
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AU2002220630A1 (en) * 2000-10-16 2002-04-29 Bayer Aktiengesellschaft Regulation of human serine-threonine protein kinase
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EP1443117B1 (en) * 2000-11-09 2010-08-11 University Of Virginia Patent Foundation Human testis specific serine/threonine kinase
EP1339866B1 (en) * 2000-11-09 2010-09-01 University Of Virginia Patent Foundation Human testis specific serine/threonine kinase
CA2430624A1 (en) * 2000-12-08 2002-06-13 Ming-Hui Wei Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
JP2004530417A (ja) 2000-12-12 2004-10-07 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
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US6410294B1 (en) * 2000-12-13 2002-06-25 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
WO2002048328A2 (en) * 2000-12-14 2002-06-20 Pe Corporation (Ny) Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof
US7119185B2 (en) * 2000-12-21 2006-10-10 Trustees Of The University Of Pennsylvania Hormonally up-regulated, neu-tumor-associated kinase
US7049118B2 (en) 2001-01-03 2006-05-23 Bayer Healthcare Ag Regulation of human serine-threonine protein kinase
WO2002055681A2 (en) * 2001-01-11 2002-07-18 Bayer Ag Regulation of human tau-tubulin kinase
DE10102797A1 (de) * 2001-01-22 2003-05-08 Deutsches Krebsforsch HIPK-Kinasen und deren Verwendung zur Beeinflussung der Zellteilung und Zellproliferation
US6686176B2 (en) * 2001-01-23 2004-02-03 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
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AU2002359869A1 (en) * 2001-12-28 2003-07-24 The Trustees Of Columbia University In The City Of New York Pak5-related compositions and methods
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CN1674929B (zh) 2002-08-14 2013-07-17 赛伦斯治疗公司 蛋白激酶Nβ的应用
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JPWO2004018669A1 (ja) * 2002-08-21 2005-12-08 株式会社プロテイン・エクスプレス 塩誘導性キナーゼ2及びその用途
WO2004032877A2 (en) 2002-10-10 2004-04-22 Wyeth Compositions, organisms and methodologies employing a novel human kinase
US20040096890A1 (en) * 2002-10-10 2004-05-20 Wyeth Compositions, organisms and methodologies employing a novel human kinase
EP1554385A2 (en) 2002-10-24 2005-07-20 Wyeth Calcineurin-like human phoshphoesterase
WO2004050831A2 (en) 2002-11-27 2004-06-17 Wyeth Compositions, organisms and methodologies employing a novel human kinase
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US8399637B2 (en) * 2006-08-24 2013-03-19 The Trustees Of The University Of Pennsylvania Nucleic acids encoding proteins for modulating Na,K-ATPase
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
JP2008522596A (ja) * 2004-12-10 2008-07-03 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 血清/糖質コルチコイド調節キナーゼの使用

Also Published As

Publication number Publication date
AU5173400A (en) 2000-12-18
US20060234344A1 (en) 2006-10-19
WO2000073469A2 (en) 2000-12-07
CA2383244A1 (en) 2000-12-07
EP1180151A2 (en) 2002-02-20
WO2000073469A3 (en) 2001-11-29

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