CA2383244A1 - Protein kinases - Google Patents

Protein kinases Download PDF

Info

Publication number
CA2383244A1
CA2383244A1 CA002383244A CA2383244A CA2383244A1 CA 2383244 A1 CA2383244 A1 CA 2383244A1 CA 002383244 A CA002383244 A CA 002383244A CA 2383244 A CA2383244 A CA 2383244A CA 2383244 A1 CA2383244 A1 CA 2383244A1
Authority
CA
Canada
Prior art keywords
seq
polypeptide
kinase
group
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002383244A
Other languages
English (en)
French (fr)
Inventor
Gregory D. Plowman
Ricardo Martinez
David Whyte
Sucha Sudersanam
Gerard Manning
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sugen LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2383244A1 publication Critical patent/CA2383244A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002383244A 1999-05-28 2000-05-26 Protein kinases Abandoned CA2383244A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13650399P 1999-05-28 1999-05-28
US60/136,503 1999-05-28
PCT/US2000/014842 WO2000073469A2 (en) 1999-05-28 2000-05-26 Protein kinases

Publications (1)

Publication Number Publication Date
CA2383244A1 true CA2383244A1 (en) 2000-12-07

Family

ID=22473127

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002383244A Abandoned CA2383244A1 (en) 1999-05-28 2000-05-26 Protein kinases

Country Status (6)

Country Link
US (1) US20060234344A1 (enExample)
EP (1) EP1180151A2 (enExample)
JP (1) JP2003501038A (enExample)
AU (1) AU5173400A (enExample)
CA (1) CA2383244A1 (enExample)
WO (1) WO2000073469A2 (enExample)

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US20030028004A1 (en) * 2000-12-22 2003-02-06 Millennium Pharmaceuticals, Inc. 68730 and 69112, protein kinase molecules and uses therefor
US6660490B2 (en) * 1998-12-11 2003-12-09 Millennnium Pharmaceuticals, Inc. CARK protein and nucleic acid molecules and uses therefor
US6261818B1 (en) * 1998-12-11 2001-07-17 Millennium Pharmaceuticals, Inc. CARK protein and nucleic acid molecules and uses therefor
AU5446900A (en) 1999-05-28 2000-12-18 Immunex Corporation Novel murine and human kinases
US7001752B1 (en) 1999-05-28 2006-02-21 Immunex Corporation Murine and human kinases
US6656698B1 (en) * 1999-06-30 2003-12-02 Millennium Pharmaceuticals, Inc. 12832, a novel human kinase-like molecule and uses thereof
WO2001023579A1 (en) * 1999-09-28 2001-04-05 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US6579710B2 (en) 2000-12-12 2003-06-17 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
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EP1484408A1 (en) * 1999-09-28 2004-12-08 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
CA2382859A1 (en) * 1999-10-07 2001-04-12 Genentech, Inc. Novel polypeptides, their nucleic acids, and methods for their use in angiogenesis and vascularization
US6428980B1 (en) 1999-11-16 2002-08-06 Rigel Pharmaceuticals, Inc. Nucleic acids encoding RIP3 associated cell cycle proteins
JP2003514583A (ja) * 1999-11-24 2003-04-22 スージェン・インコーポレーテッド 新規ヒト蛋白質キナーゼおよび蛋白質キナーゼ様酵素
JP2005503751A (ja) * 1999-12-10 2005-02-10 インサイト・ゲノミックス・インコーポレイテッド 細胞外マトリックスおよび細胞接着分子
GB9929542D0 (en) * 1999-12-14 2000-02-09 Glaxo Wellcome Kk Ikk4
WO2001059081A2 (en) * 2000-02-09 2001-08-16 Millennium Pharmaceuticals, Inc. Methods for using 20893, a human protein kinase
JP2004502404A (ja) * 2000-02-17 2004-01-29 インサイト・ゲノミックス・インコーポレイテッド ヒトキナーゼ
US6864078B2 (en) * 2000-02-29 2005-03-08 Millennium Pharmaceuticals, Inc. 14790, novel protein kinase molecule and uses therefor
US7198930B2 (en) 2000-02-29 2007-04-03 Millennium Pharmaceuticals, Inc. Human protein kinase, phosphatase, and protease family members and uses thereof
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US6458561B1 (en) 2000-03-13 2002-10-01 Incyte Genomics, Inc. Human NIM1 kinase
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US20030198953A1 (en) * 2000-03-30 2003-10-23 Spytek Kimberly A. Novel proteins and nucleic acids encoding same
WO2001079488A2 (en) * 2000-04-13 2001-10-25 Millennium Pharmaceuticals, Inc. 14257,protein kinase molecules and uses therefor
WO2001081558A2 (en) * 2000-04-25 2001-11-01 Millennium Pharmaceuticals, Inc. 13295 novel protein kinase molecules and uses therefor
AU2001257195B2 (en) 2000-04-25 2006-10-05 Lexicon Pharmaceuticals, Inc. Novel human kinase proteins and polynucleotides encoding the same
EP1278864A2 (en) * 2000-05-12 2003-01-29 MERCK PATENT GmbH Serine-threonine kinase-3
EP1278863A2 (en) * 2000-05-12 2003-01-29 MERCK PATENT GmbH Human serine-threonine kinase-4
WO2001090160A2 (en) * 2000-05-26 2001-11-29 Bayer Aktiengesellschaft REGULATION OF HUMAN p78-LIKE SERINE/THREONINE KINASE
US6413756B2 (en) 2000-06-06 2002-07-02 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
US6416990B2 (en) 2000-06-06 2002-07-09 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
US6323016B1 (en) 2000-06-09 2001-11-27 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
EP1290187A2 (en) * 2000-06-15 2003-03-12 Incyte Genomics, Inc. Humain kinases
EP1358336A2 (en) * 2000-07-05 2003-11-05 MERCK PATENT GmbH Human serine-threonine kinase
EP1322768A2 (en) * 2000-07-28 2003-07-02 Chiron Corporation Isolation of drosophila and human polynucleotides encoding par-1 kinase, polypeptides encoded by the polynucleotides and methods utilizing the polynucleotides and polypeptides
EP1307546A2 (en) * 2000-08-03 2003-05-07 1149336 Ontario Inc. Ampk-related serine/threonine kinase, designated snark
US6759221B1 (en) * 2000-08-18 2004-07-06 Millennium Pharmaceuticals, Inc. 14189, a novel human kinase and uses thereof
EP1320592A2 (en) * 2000-08-21 2003-06-25 Millennium Pharmaceuticals, Inc. "15985", a human serine/threonine protein kinase family member and uses thereof
US6455291B1 (en) * 2000-08-24 2002-09-24 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
US6555352B2 (en) * 2000-08-31 2003-04-29 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
US6372468B1 (en) * 2000-09-14 2002-04-16 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
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AU2001294741A1 (en) * 2000-09-25 2002-04-02 Millennium Pharmaceuticals, Inc. 3700, a novel human protein kinase and uses therefor
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AU2002220630A1 (en) * 2000-10-16 2002-04-29 Bayer Aktiengesellschaft Regulation of human serine-threonine protein kinase
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EP1443117B1 (en) * 2000-11-09 2010-08-11 University Of Virginia Patent Foundation Human testis specific serine/threonine kinase
AU2002239483A1 (en) * 2000-12-08 2002-06-18 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
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US6410294B1 (en) * 2000-12-13 2002-06-25 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
WO2002048328A2 (en) * 2000-12-14 2002-06-20 Pe Corporation (Ny) Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof
US7119185B2 (en) * 2000-12-21 2006-10-10 Trustees Of The University Of Pennsylvania Hormonally up-regulated, neu-tumor-associated kinase
US7049118B2 (en) 2001-01-03 2006-05-23 Bayer Healthcare Ag Regulation of human serine-threonine protein kinase
WO2002055681A2 (en) * 2001-01-11 2002-07-18 Bayer Ag Regulation of human tau-tubulin kinase
DE10102797A1 (de) * 2001-01-22 2003-05-08 Deutsches Krebsforsch HIPK-Kinasen und deren Verwendung zur Beeinflussung der Zellteilung und Zellproliferation
US6686176B2 (en) * 2001-01-23 2004-02-03 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
EP1227156A3 (en) * 2001-01-30 2004-01-02 Aeomica, Inc. A human protein kinase domain-containing protein
US6492154B2 (en) * 2001-01-31 2002-12-10 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
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US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same
US20030036183A1 (en) * 2001-05-10 2003-02-20 Boylan John F. Serine threonine kinase member, h2520-40
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AU2002312976A1 (en) * 2001-06-07 2002-12-16 Bayer Aktiengesellschaft Human serine/threonine protein kinase-like enzyme
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US20040096890A1 (en) * 2002-10-10 2004-05-20 Wyeth Compositions, organisms and methodologies employing a novel human kinase
US7208306B2 (en) 2002-10-24 2007-04-24 Wyeth Compositions employing a novel human protein phosphatase
AU2003290664A1 (en) 2002-11-27 2004-06-23 Wei Liu Compositions, organisms and methodologies employing a novel human kinase
US7829682B1 (en) * 2003-04-30 2010-11-09 Incyte Corporation Human β-adrenergic receptor kinase nucleic acid molecule
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CN101490253A (zh) 2006-07-21 2009-07-22 赛伦斯治疗公司 用于抑制蛋白激酶3表达的方法
US8399637B2 (en) * 2006-08-24 2013-03-19 The Trustees Of The University Of Pennsylvania Nucleic acids encoding proteins for modulating Na,K-ATPase
EP2486130A1 (en) * 2009-10-06 2012-08-15 Tallinn University Of Technology Inhibition or activation of serine/threonine ulk3 kinase activity
WO2025006571A1 (en) * 2023-06-26 2025-01-02 University Of Kentucky Research Foundation Targeted destruction of pask by peptide-based degron

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Also Published As

Publication number Publication date
WO2000073469A2 (en) 2000-12-07
EP1180151A2 (en) 2002-02-20
WO2000073469A3 (en) 2001-11-29
AU5173400A (en) 2000-12-18
US20060234344A1 (en) 2006-10-19
JP2003501038A (ja) 2003-01-14

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