JP2003500457A5 - - Google Patents
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- JP2003500457A5 JP2003500457A5 JP2000620991A JP2000620991A JP2003500457A5 JP 2003500457 A5 JP2003500457 A5 JP 2003500457A5 JP 2000620991 A JP2000620991 A JP 2000620991A JP 2000620991 A JP2000620991 A JP 2000620991A JP 2003500457 A5 JP2003500457 A5 JP 2003500457A5
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- pdx
- cells
- expression
- cell
- insulin
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| US6774120B1 (en) | 1999-06-01 | 2004-08-10 | Sarah Ferber | Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues |
| US8778899B2 (en) | 1999-06-01 | 2014-07-15 | Sarah Ferber | Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues |
| US7567870B1 (en) * | 2000-07-31 | 2009-07-28 | Institute For Systems Biology | Multiparameter analysis for predictive medicine |
| WO2002079457A1 (en) | 2001-03-29 | 2002-10-10 | Ixion Biotechnology, Inc. | Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway |
| US7343247B2 (en) * | 2001-07-30 | 2008-03-11 | The Institute For Systems Biology | Methods of classifying drug responsiveness using multiparameter analysis |
| US20050053588A1 (en) * | 2001-10-18 | 2005-03-10 | Li Yin | Conversion of liver stem and progenitor cells to pancreatic functional cells |
| GB2399823B (en) | 2001-12-07 | 2006-02-15 | Geron Corp | Islet cells from primate pluripotent stem cells |
| CA2468335C (en) | 2001-12-07 | 2014-07-08 | Geron Corporation | Chondrocyte precursors derived from human embryonic stem cells |
| JP2003189875A (ja) * | 2001-12-28 | 2003-07-08 | Japan Science & Technology Corp | 膵β細胞関連転写因子の遺伝子導入によるインスリン産生細胞の形成誘導 |
| GB0206357D0 (en) * | 2002-03-18 | 2002-05-01 | Univ Bath | Cells |
| JP4136434B2 (ja) * | 2002-04-17 | 2008-08-20 | 進 清野 | インスリン産生細胞の誘導 |
| GB0300208D0 (en) * | 2003-01-06 | 2003-02-05 | Oxford Biomedica Ltd | Insulin producing cells |
| CA2820537C (en) | 2003-04-23 | 2015-10-20 | Valeritas, Inc. | Hydraulically actuated pump for fluid administration |
| EP1624898A1 (en) * | 2003-05-12 | 2006-02-15 | Sarah Ferber | Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues |
| US20080267928A1 (en) * | 2004-02-23 | 2008-10-30 | Lijun Yang | Compositions and Methods for Making Insulin-Producing Cells |
| US9089636B2 (en) | 2004-07-02 | 2015-07-28 | Valeritas, Inc. | Methods and devices for delivering GLP-1 and uses thereof |
| WO2006010531A1 (en) * | 2004-07-28 | 2006-02-02 | F. Hoffmann-La Roche Ag | Prohormone convertase i as target/marker for beta cell failure |
| EP1833494B1 (en) * | 2005-01-07 | 2016-05-18 | Wake Forest University Health Sciences | Regeneration of pancreatic islets by amniotic fluid stem cell therapy |
| JP2007061096A (ja) * | 2005-08-31 | 2007-03-15 | Lifescan Inc | 細胞分化を促進する方法 |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| WO2007071339A1 (en) | 2005-12-21 | 2007-06-28 | Universite Catholique De Louvain | Isolated liver stem cells |
| JP5302012B2 (ja) | 2006-03-08 | 2013-10-02 | タケダ カリフォルニア インコーポレイテッド | グルコキナーゼ活性剤 |
| ES2656675T3 (es) | 2006-03-30 | 2018-02-28 | Valeritas, Inc. | Dispositivo de suministro de fluidos de múltiples cartuchos |
| JP5386350B2 (ja) | 2006-05-31 | 2014-01-15 | タケダ カリフォルニア インコーポレイテッド | グルコキナーゼ活性剤としての、インダゾールおよびイソインドール誘導体 |
| US8415153B2 (en) | 2006-06-19 | 2013-04-09 | Geron Corporation | Differentiation and enrichment of islet-like cells from human pluripotent stem cells |
| JP5419706B2 (ja) | 2006-12-20 | 2014-02-19 | タケダ カリフォルニア インコーポレイテッド | グルコキナーゼアクチベーター |
| US8173645B2 (en) | 2007-03-21 | 2012-05-08 | Takeda San Diego, Inc. | Glucokinase activators |
| CN102154210A (zh) * | 2010-12-28 | 2011-08-17 | 沈达青 | 一种胰岛素基因修饰的肝干细胞制法及其应用和制剂 |
| SG11201510209SA (en) | 2013-06-13 | 2016-01-28 | Orgenesis Ltd | Cell populations, methods of transdifferention and methods of use thereof |
| DK3016665T3 (da) | 2013-07-05 | 2019-11-25 | Univ Catholique Louvain | Konditioneret medium fra humane voksne leverstamceller og dets anvendelse i behandlingen af leverlidelser |
| MA41296A (fr) | 2014-12-30 | 2017-11-07 | Orgenesis Ltd | Procédés de transdifférenciation et procédés d'utilisation de ceux-ci |
| EP3635106A4 (en) | 2017-05-08 | 2021-01-06 | Orgenesis Ltd. | POPULATIONS OF TRANSDIFFERENTIATED CELLS AND THEIR METHODS OF USE |
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