|
WO2000028020A2
(en)
*
|
1998-11-10 |
2000-05-18 |
Board Of Regents, The University Of Texas System |
Methods for preventing cardiac hypertrophy and heart failure by inhibition of mef2 transcription factor
|
|
JP2001149081A
(ja)
*
|
1999-11-29 |
2001-06-05 |
Cyclex Co Ltd |
脱アセチル化酵素の活性測定方法、並びにこれら酵素の阻害剤もしくは促進剤のスクリーニング方法
|
|
PE20020354A1
(es)
*
|
2000-09-01 |
2002-06-12 |
Novartis Ag |
Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
|
|
US6706686B2
(en)
*
|
2001-09-27 |
2004-03-16 |
The Regents Of The University Of Colorado |
Inhibition of histone deacetylase as a treatment for cardiac hypertrophy
|
|
US7154002B1
(en)
|
2002-10-08 |
2006-12-26 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US20040077083A1
(en)
*
|
2002-10-17 |
2004-04-22 |
Isis Pharmaceuticals Inc. |
Antisense modulation of histone deacetylase 4 expression
|
|
US7250514B1
(en)
|
2002-10-21 |
2007-07-31 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US20070104688A1
(en)
*
|
2003-02-13 |
2007-05-10 |
City Of Hope |
Small interfering RNA mediated transcriptional gene silencing in mammalian cells
|
|
US20040171118A1
(en)
*
|
2003-02-13 |
2004-09-02 |
City Of Hope |
Methods for directing DNA methylation in mammalian cells using homologous short double stranded RNAs
|
|
US7375228B2
(en)
*
|
2003-03-17 |
2008-05-20 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
MXPA05012619A
(es)
*
|
2003-05-21 |
2006-02-08 |
Univ Texas |
Inhibicion de la proteina cinasa c-mu como un tratamiento para la hipertrofia cardiaca y la falla cardiaca.
|
|
JP2007504131A
(ja)
*
|
2003-08-29 |
2007-03-01 |
エートン ファーマ インコーポレーティッド |
癌の組み合わせ処置法
|
|
WO2005065681A1
(en)
*
|
2003-12-19 |
2005-07-21 |
Takeda San Diego, Inc. |
N- hydroxy-3-(3-(1h-imidazol-2-yl)-phenyl)-acrylamide derivatives and related compounds as histone deacetylase (hdac) inhibitors for the treatment of cancer
|
|
WO2005066151A2
(en)
*
|
2003-12-19 |
2005-07-21 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US20050283841A1
(en)
*
|
2004-02-02 |
2005-12-22 |
Mckinsey Timothy A |
Inhibition of protein kinase C-related kinase (PRK) as a treatment for cardiac hypertrophy and heart failure
|
|
US20050197336A1
(en)
*
|
2004-03-08 |
2005-09-08 |
Miikana Therapeutics Corporation |
Inhibitors of histone deacetylase
|
|
US7345043B2
(en)
*
|
2004-04-01 |
2008-03-18 |
Miikana Therapeutics |
Inhibitors of histone deacetylase
|
|
US20050288215A1
(en)
*
|
2004-04-05 |
2005-12-29 |
Mckinsey Timothy A |
Inhibition of nuclear export as a treatment for cardiac hypertrophy and heart failure
|
|
EP1740945B1
(en)
|
2004-04-07 |
2018-09-19 |
Ncardia AG |
Non-invasive, in vitro functional tissue assay systems
|
|
ES2354997T3
(es)
|
2004-05-11 |
2011-03-21 |
Axiogenesis Ag |
Ensayo para el descubrimiento de fármacos basado en células diferenciadas in vitro.
|
|
FI20040675A0
(fi)
*
|
2004-05-12 |
2004-05-12 |
Orion Corp |
Menetelmä sydämen hypertrofian hoitoon ja estoon
|
|
US20060110390A1
(en)
*
|
2004-08-25 |
2006-05-25 |
Myogen, Inc. |
Inhibition of Ku as a treatment for cardiovascular diseases
|
|
WO2006060382A2
(en)
*
|
2004-11-30 |
2006-06-08 |
Trustees Of The University Of Pennsylvania |
Use of hdac and/or dnmt inhibitors for treatment of ischemic injury
|
|
WO2006066133A2
(en)
*
|
2004-12-16 |
2006-06-22 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US7772245B2
(en)
|
2005-02-14 |
2010-08-10 |
Miikana Therapeutics, Inc. |
Inhibitors of histone deacetylase
|
|
WO2006094068A2
(en)
*
|
2005-03-01 |
2006-09-08 |
The Regents Of The University Of Michigan |
Hdac inhibitors that promote brm expression and brm related diagnostics
|
|
US20100087328A1
(en)
*
|
2005-03-01 |
2010-04-08 |
The Regents Of The University Of Michigan |
Brm expression and related diagnostics
|
|
JP2008540574A
(ja)
*
|
2005-05-11 |
2008-11-20 |
タケダ サン ディエゴ インコーポレイテッド |
ヒストンデアセチラーゼ阻害剤
|
|
EP1901764A1
(en)
*
|
2005-07-14 |
2008-03-26 |
Myogen, Inc. |
Use of inhibitors of the ubiquitin proteasome pathway for increasing contractility of the heart
|
|
WO2007011626A2
(en)
*
|
2005-07-14 |
2007-01-25 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US20090012066A1
(en)
*
|
2005-08-10 |
2009-01-08 |
Novartis Ag |
Method of Use of Deacetylase Inhibitors
|
|
US20070129290A1
(en)
*
|
2005-11-18 |
2007-06-07 |
Or Yat S |
Metabolite derivatives of the HDAC inhibitor FK228
|
|
US7863414B2
(en)
|
2005-11-18 |
2011-01-04 |
The Board Of Regents Of The University Of Texas Systems |
Methods of treatment and uses for CaMKII and its interaction with HDACs and calpain
|
|
US20070207950A1
(en)
*
|
2005-12-21 |
2007-09-06 |
Duke University |
Methods and compositions for regulating HDAC6 activity
|
|
JP2009525955A
(ja)
*
|
2006-01-13 |
2009-07-16 |
タケダ サン ディエゴ インコーポレイテッド |
ヒストンデアセチラーゼ阻害剤
|
|
US20100226857A1
(en)
*
|
2006-03-29 |
2010-09-09 |
Jeannine Strobl |
Tumor cell differentiation agents as chemical inhibitors and treatments for intracellular parasites
|
|
KR20080108156A
(ko)
*
|
2006-04-06 |
2008-12-11 |
노파르티스 아게 |
유기 화합물의 조합물
|
|
AU2007238600B2
(en)
*
|
2006-04-13 |
2012-01-19 |
Wake Forest University Health Sciences |
C-nitroso-derived nitroxyl donors
|
|
WO2007145704A2
(en)
*
|
2006-04-24 |
2007-12-21 |
Gloucester Pharmaceuticals |
Gemcitabine combination therapy
|
|
US8957027B2
(en)
*
|
2006-06-08 |
2015-02-17 |
Celgene Corporation |
Deacetylase inhibitor therapy
|
|
CN101801994A
(zh)
*
|
2006-12-29 |
2010-08-11 |
格洛斯特制药公司 |
制备Romidepsin
|
|
AU2007342030B2
(en)
*
|
2006-12-29 |
2013-08-15 |
Celgene Corporation |
Romidepsin-based treatments for cancer
|
|
US9884031B2
(en)
*
|
2007-05-09 |
2018-02-06 |
The Trustees Of The University Of Pennsylvania |
Use of HDAC inhibitors for treatment of cardiac rhythm disorders
|
|
US7737175B2
(en)
*
|
2007-06-01 |
2010-06-15 |
Duke University |
Methods and compositions for regulating HDAC4 activity
|
|
WO2009048540A1
(en)
*
|
2007-10-05 |
2009-04-16 |
U.S. Department Of Veterans Affairs Office Of General Counsel - Psg Iv (024) |
Method and composition for treating heart failure
|
|
WO2009089598A2
(en)
*
|
2008-01-18 |
2009-07-23 |
Katholieke Universiteit Leuven |
Msmb-gene methylation based diagnosis, staging and prognosis of prostate cancer
|
|
WO2010039697A2
(en)
*
|
2008-09-30 |
2010-04-08 |
Gilead Sciences, Inc. |
Selective inhibition of histone deacetylases 1 and 2 as a treatment for cardiac hypertrophy
|
|
WO2011032088A1
(en)
|
2009-09-11 |
2011-03-17 |
Arca Biopharma, Inc. |
Polymorphisms in the pde3a gene
|
|
EP2593123B1
(en)
|
2010-07-12 |
2019-09-04 |
Celgene Corporation |
Romidepsin solid forms and uses thereof
|
|
US8859502B2
(en)
|
2010-09-13 |
2014-10-14 |
Celgene Corporation |
Therapy for MLL-rearranged leukemia
|
|
RS58895B1
(sr)
|
2010-10-13 |
2019-08-30 |
Medivir Ab |
Farmaceutska formulacija za inhibitore histonske deacetilaze
|
|
AU2013202506B2
(en)
|
2012-09-07 |
2015-06-18 |
Celgene Corporation |
Resistance biomarkers for hdac inhibitors
|
|
AU2013202507B9
(en)
|
2012-11-14 |
2015-08-13 |
Celgene Corporation |
Inhibition of drug resistant cancer cells
|
|
NZ630311A
(en)
|
2013-12-27 |
2016-03-31 |
Celgene Corp |
Romidepsin formulations and uses thereof
|
|
TWI808055B
(zh)
|
2016-05-11 |
2023-07-11 |
美商滬亞生物國際有限公司 |
Hdac 抑制劑與 pd-1 抑制劑之組合治療
|
|
TWI794171B
(zh)
|
2016-05-11 |
2023-03-01 |
美商滬亞生物國際有限公司 |
Hdac抑制劑與pd-l1抑制劑之組合治療
|
|
CA3156303A1
(en)
*
|
2019-10-03 |
2021-04-08 |
Tenaya Therapeutics, Inc. |
5-fluoronicotinamide derivatives and uses thereof
|
|
WO2021127643A1
(en)
|
2019-12-20 |
2021-06-24 |
Tenaya Therapeutics, Inc. |
Fluoroalkyl-oxadiazoles and uses thereof
|
|
US20240252502A1
(en)
|
2021-05-04 |
2024-08-01 |
Tenaya Therapeutics, Inc. |
Hdac6 inhibitors for treatment of metabolic disease and hfpef
|
|
CN116942822A
(zh)
*
|
2023-06-12 |
2023-10-27 |
深圳大学 |
Hdac2在治疗室性心律失常中的应用
|
|
CN118766882B
(zh)
*
|
2024-09-12 |
2025-02-21 |
北京大学第三医院(北京大学第三临床医学院) |
用于治疗心血管疾病的制剂及其应用和制备方法
|